Contents: July 2000, Volume 44, Issue 7        Minireviews        Mechanisms of Resistance        Antiviral Agents        Experimental Therapeutics        Clinical Therapeutics        Susceptibility        Mechanisms of Action        Pharmacology        Letters Other Issues

Table of Contents

[Index by Author]

To see an article, click its [Full Text], [Abstract] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

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Minireviews:

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Mutation Frequencies and Antibiotic Resistance J. L. Martinez and F. Baquero Antimicrob. Agents Chemother. July 2000 44: 1771-1777; [Full Text] [PDF] [Reprints and Permissions]

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Mechanisms of Resistance:

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Stenotrophomonas maltophilia D457R Contains a Cluster of Genes from Gram-Positive Bacteria Involved in Antibiotic and Heavy Metal Resistance Ana Alonso, Patricia Sanchez, and José L. Martínez Antimicrob. Agents Chemother. July 2000 44: 1778-1782; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Role of Antibiotic Penetration Limitation in Klebsiella pneumoniae Biofilm Resistance to Ampicillin and Ciprofloxacin Jeff N. Anderl, Michael J. Franklin, and Philip S. Stewart Antimicrob. Agents Chemother. July 2000 44: 1818-1824; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Peptide Deformylase in Staphylococcus aureus: Resistance to Inhibition Is Mediated by Mutations in the Formyltransferase Gene Peter S. Margolis, Corinne J. Hackbarth, Dennis C. Young, Wen Wang, Dawn Chen, Zhengyu Yuan, Richard White, and Joaquim Trias Antimicrob. Agents Chemother. July 2000 44: 1825-1831; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Roles of gyrA Mutations in Resistance of Clinical Isolates and In Vitro Mutants of Bacteroides fragilis to the New Fluoroquinolone Trovafloxacin Rafik Bachoual, Luc Dubreuil, Claude-James Soussy, and Jacques Tankovic Antimicrob. Agents Chemother. July 2000 44: 1842-1845; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Rapid Discriminatory Detection of Genes Coding for SHV -Lactamases by Ligase Chain Reaction Jungmin Kim and Hoan-Jong Lee Antimicrob. Agents Chemother. July 2000 44: 1860-1864; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vivo Increase in Resistance to Ciprofloxacin in Escherichia coli Associated with Deletion of the C-Terminal Part of MarR Hans-Jörg Linde, Frank Notka, Michaela Metz, Bernd Kochanowski, Peter Heisig, and Norbert Lehn Antimicrob. Agents Chemother. July 2000 44: 1865-1868; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Molecular and Biochemical Heterogeneity of Class B Carbapenem-Hydrolyzing -Lactamases in Chryseobacterium meningosepticum Samuel Bellais, Daniel Aubert, Thierry Naas, and Patrice Nordmann Antimicrob. Agents Chemother. July 2000 44: 1878-1886; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Genetic Organization of the Downstream Region of the mecA Element in Methicillin-Resistant Staphylococcus aureus Isolates Carrying Different Polymorphisms of This Region Duarte C. Oliveira, Shang W. Wu, and Hermínia de Lencastre Antimicrob. Agents Chemother. July 2000 44: 1906-1910; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Amphotericin B Resistance and Membrane Fluidity in Kluyveromyces lactis Strains Mohamed Younsi, Elise Ramanandraibe, Roger Bonaly, Mireille Donner, and Joël Coulon Antimicrob. Agents Chemother. July 2000 44: 1911-1916; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Prevalence of -Lactamases among 1,072 Clinical Strains of Proteus mirabilis: a 2-Year Survey in a French Hospital C. Chanal, R. Bonnet, C. De Champs, D. Sirot, R. Labia, and J. Sirot Antimicrob. Agents Chemother. July 2000 44: 1930-1935; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

A Novel CTX-M -Lactamase (CTX-M-8) in Cefotaxime-Resistant Enterobacteriaceae Isolated in Brazil R. Bonnet, J. L. M. Sampaio, R. Labia, C. De Champs, D. Sirot, C. Chanal, and J. Sirot Antimicrob. Agents Chemother. July 2000 44: 1936-1942; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Modulation of Erm Methyltransferase Activity by Peptides Derived from Phage Display Robert B. Giannattasio and Bernard Weisblum Antimicrob. Agents Chemother. July 2000 44: 1961-1963; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Cloning and Sequence of the Gene Encoding a Novel Cefotaxime-Hydrolyzing -Lactamase (CTX-M-9) from Escherichia coli in Spain Montserrat Sabaté, Raül Tarragó, Ferran Navarro, Elisenda Miró, Clara Vergés, Jordi Barbé, and Guillermo Prats Antimicrob. Agents Chemother. July 2000 44: 1970-1973; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Antiviral Agents:

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In Vitro Selection of Mutations in the Human Immunodeficiency Virus Type 1 Reverse Transcriptase That Decrease Susceptibility to ()--D-Dioxolane-Guanosine and Suppress Resistance to 3'-Azido-3'-Deoxythymidine Holly Z. Bazmi, Jennifer L. Hammond, Socrates C. H. Cavalcanti, Chung K. Chu, Raymond F. Schinazi, and John W. Mellors Antimicrob. Agents Chemother. July 2000 44: 1783-1788; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Correlation between Pretreatment Levels of Interferon Response Genes and Clinical Responses to an Immune Response Modifier (Imiquimod) in Genital Warts I. Arany, S. K. Tyring, M. M. Brysk, M. A. Stanley, M. A. Tomai, R. L. Miller, M. H. Smith, D. J. McDermott, and H. B. Slade Antimicrob. Agents Chemother. July 2000 44: 1869-1873; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Effect of Zidovudine on the Primary Cytolytic T-Lymphocyte Response and T-Cell Effector Function Sabine Francke, Charles G. Orosz, Kathleen A. Hayes, and Lawrence E. Mathes Antimicrob. Agents Chemother. July 2000 44: 1900-1905; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Sodium Dodecyl Sulfate and C31G as Microbicidal Alternatives to Nonoxynol 9: Comparative Sensitivity of Primary Human Vaginal Keratinocytes Fred C. Krebs, Shendra R. Miller, Bradley J. Catalone, Patricia A. Welsh, Daniel Malamud, Mary K. Howett, and Brian Wigdahl Antimicrob. Agents Chemother. July 2000 44: 1954-1960; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antiviral Activities of Oral 1-O-Hexadecylpropanediol-3-Phosphoacyclovir and Acyclovir in Woodchucks with Chronic Woodchuck Hepatitis Virus Infection Karl Y. Hostetler, James R. Beadle, William E. Hornbuckle, Christine A. Bellezza, Ilia A. Tochkov, Paul J. Cote, John L. Gerin, Brent E. Korba, and Bud C. Tennant Antimicrob. Agents Chemother. July 2000 44: 1964-1969; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Experimental Therapeutics:

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Quinupristin-Dalfopristin Combined with -Lactams for Treatment of Experimental Endocarditis Due to Staphylococcus aureus Constitutively Resistant to Macrolide-Lincosamide-Streptogramin B Antibiotics J. Vouillamoz, J. M. Entenza, C. Féger, M. P. Glauser, and P. Moreillon Antimicrob. Agents Chemother. July 2000 44: 1789-1795; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Comparison of the Echinocandin Caspofungin with Amphotericin B for Treatment of Histoplasmosis following Pulmonary Challenge in a Murine Model Steve Kohler, L. Joseph Wheat, Patricia Connolly, Carol Schnizlein-Bick, Michelle Durkin, Melinda Smedema, Janet Goldberg, and Edward Brizendine Antimicrob. Agents Chemother. July 2000 44: 1850-1854; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Efficacies of Sordarin Derivatives GM193663, GM211676, and GM237354 in a Murine Model of Systemic Coccidioidomycosis Karl V. Clemons and David A. Stevens Antimicrob. Agents Chemother. July 2000 44: 1874-1877; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Comparison of a Rabbit Model of Bacterial Endocarditis and an In Vitro Infection Model with Simulated Endocardial Vegetations Ellie Hershberger, Elizabeth A. Coyle, Glenn W. Kaatz, Marcus J. Zervos, and Michael J. Rybak Antimicrob. Agents Chemother. July 2000 44: 1921-1924; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activities of Daptomycin, Arbekacin, Vancomycin, and Gentamicin Alone and/or in Combination against Glycopeptide Intermediate-Resistant Staphylococcus aureus in an Infection Model Ronda L. Akins and Michael J. Rybak Antimicrob. Agents Chemother. July 2000 44: 1925-1929; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mycobacterium avium Grown in Acanthamoeba castellanii Is Protected from the Effects of Antimicrobials Elizabeth C. Miltner and Luiz E. Bermudez Antimicrob. Agents Chemother. July 2000 44: 1990-1994; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Combination Antifungal Therapy in Treatment of Murine Pulmonary Mucormycosis: Roles of Quinolones and Azoles Alan M. Sugar and Xiu-Ping Liu Antimicrob. Agents Chemother. July 2000 44: 2004-2006; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Clinical Therapeutics:

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Clinical Efficacy of Intravenous followed by Oral Azithromycin Monotherapy in Hospitalized Patients with Community-Acquired Pneumonia Joseph Plouffe, Douglas B. Schwartz, Antonia Kolokathis, Bruce W. Sherman, Paul M. Arnow, John A. Gezon, Byungse Suh, Antonio Anzuetto, Richard N. Greenberg, Michael Niederman, Joseph A. Paladino, Julio A. Ramirez, Jill Inverso, Charles A. Knirsch, and the Azithromycin Intravenous Clinical Trials Group Antimicrob. Agents Chemother. July 2000 44: 1796-1802; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

A Randomized Controlled Comparison of Azithromycin and Ofloxacin for Treatment of Multidrug-Resistant or Nalidixic Acid-Resistant Enteric Fever Nguyen Tran Chinh, Christopher M. Parry, Nguyen Thi Ly, Huynh Duy Ha, Mai Xuan Thong, To Song Diep, John Wain, Nicholas J. White, and Jeremy J. Farrar Antimicrob. Agents Chemother. July 2000 44: 1855-1859; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Itraconazole Oral Solution for Primary Prophylaxis of Fungal Infections in Patients with Hematological Malignancy and Profound Neutropenia: a Randomized, Double-Blind, Double-Placebo, Multicenter Trial Comparing Itraconazole and Amphotericin B J. L. Harousseau, A. W. Dekker, A. Stamatoullas-Bastard, A. Fassas, W. Linkesch, J. Gouveia, R. De Bock, M. Rovira, W. F. Seifert, H. Joosen, M. Peeters, and K. De Beule Antimicrob. Agents Chemother. July 2000 44: 1887-1893; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Susceptibility:

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IB-367, a Protegrin Peptide with In Vitro and In Vivo Activities against the Microflora Associated with Oral Mucositis Deborah A. Mosca, Malinda A. Hurst, Wendy So, Beverly S. C. Viajar, Craig A. Fujii, and Timothy J. Falla Antimicrob. Agents Chemother. July 2000 44: 1803-1808; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Comparative In Vitro Activities of Linezolid, Quinupristin-Dalfopristin, Moxifloxacin, and Trovafloxacin against Erythromycin-Susceptible and -Resistant Streptococci Carmen Betriu, Montserrat Redondo, M. Luisa Palau, Ana Sánchez, María Gómez, Esther Culebras, Ana Boloix, and Juan J. Picazo Antimicrob. Agents Chemother. July 2000 44: 1838-1841; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Pharmacodynamics of the New Ketolides HMR 3004 and HMR 3647 (Telithromycin) against Chlamydia pneumoniae I. Gustafsson, E. Hjelm, and O. Cars Antimicrob. Agents Chemother. July 2000 44: 1846-1849; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antipneumococcal Activity of ABT-773 Compared to Those of 10 Other Agents Todd A. Davies, Lois M. Ednie, Dianne M. Hoellman, Glenn A. Pankuch, Michael R. Jacobs, and Peter C. Appelbaum Antimicrob. Agents Chemother. July 2000 44: 1894-1899; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activities of Linezolid Alone and in Combination with Amoxicillin, Clarithromycin, and Metronidazole against Helicobacter pylori Alexander M. Hirschl, Petra Apfalter, Athanasios Makristathis, Manfred L. Rotter, and Margit Wimmer Antimicrob. Agents Chemother. July 2000 44: 1977-1979; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Comparative Activities of Telithromycin (HMR 3647), Levofloxacin, and Other Antimicrobial Agents against Human Mycoplasmas C. M. Bebear, H. Renaudin, A. Bryskier, and C. Bebear Antimicrob. Agents Chemother. July 2000 44: 1980-1982; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Susceptibilities of Yersinia pestis Strains to 12 Antimicrobial Agents Jane D. Wong, Jason R. Barash, Rebecca F. Sandfort, and J. Michael Janda Antimicrob. Agents Chemother. July 2000 44: 1995-1996; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antimicrobial Susceptibility and Clinical Sources of Dolosigranulum pigrum Cultures L. Laclaire and R. Facklam Antimicrob. Agents Chemother. July 2000 44: 2001-2003; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Mechanisms of Action:

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Genetic Localization and Molecular Characterization of the nonS Gene Required for Macrotetrolide Biosynthesis in Streptomyces griseus DSM40695 Wyatt C. Smith, Longkuan Xiang, and Ben Shen Antimicrob. Agents Chemother. July 2000 44: 1809-1817; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Effect of Polygodial on the Mitochondrial ATPase of Saccharomyces cerevisiae Christopher S. Lunde and Isao Kubo Antimicrob. Agents Chemother. July 2000 44: 1943-1953; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Role of Putative Loops 2 and 3 in Imipenem Passage through the Specific Porin OprD of Pseudomonas aeruginosa Martina M. Ochs, Manjeet Bains, and Robert E. W. Hancock Antimicrob. Agents Chemother. July 2000 44: 1983-1985; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Effects of Amphotericin B and Three Azole Derivatives on the Lipids of Yeast Cells of Paracoccidioides brasiliensis Rosane Christine Hahn and Júnia Soares Hamdan Antimicrob. Agents Chemother. July 2000 44: 1997-2000; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Pharmacology:

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A Population Pharmacokinetic Analysis of Nelfinavir Mesylate in Human Immunodeficiency Virus-Infected Patients Enrolled in a Phase III Clinical Trial Kimberley A. Jackson, Sara E. Rosenbaum, Bradley M. Kerr, Yazdi K. Pithavala, Geoffrey Yuen, and Michael N. Dudley Antimicrob. Agents Chemother. July 2000 44: 1832-1837; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Evaluation of Voriconazole Pharmacodynamics Using Time-Kill Methodology Michael E. Klepser, Dennis Malone, Russell E. Lewis, Erika J. Ernst, and Michael A. Pfaller Antimicrob. Agents Chemother. July 2000 44: 1917-1920; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Direct Measurement of the Anti-Influenza Agent Zanamivir in the Respiratory Tract following Inhalation Amy W. Peng, Stefano Milleri, and Daniel S. Stein Antimicrob. Agents Chemother. July 2000 44: 1974-1976; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pharmacokinetics of Zidovudine Phosphorylation in Human Immunodeficiency Virus-Positive Thai Patients and Healthy Volunteers Yupaporn Wattanagoon, Kesara Na Bangchang, Patrick G. Hoggard, Saye H. Khoo, Sara E. Gibbons, Danabhand Phiboonbhanakit, Juntra Karbwang, and David J. Back Antimicrob. Agents Chemother. July 2000 44: 1986-1989; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Letters:

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Novel Fosfomycin Resistance of Pseudomonas aeruginosa Clinical Isolates Recovered in Japan in 1996 Masaki Shimizu, Fritz Shigenobu, Izumi Miyakozawa, Akio Nakamura, Kyoko Nakazawa, Masato Suzuki, Satoko Mizukoshi, Koji O'Hara, Tetsuo Sawai, and Division of Microbial Chemistry Antimicrob. Agents Chemother. July 2000 44: 2007-2008; [Full Text] [PDF] [Reprints and Permissions]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.