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Minireviews:

Morton N. Swartz

Impact of Antimicrobial Agents and Chemotherapy from 1972 to 1998
Antimicrob. Agents Chemother. 2000 44: 2009-2016. [Full Text] [PDF] [Reprints and Permissions]  

Experimental Therapeutics:

Anthony Cacciapuoti, David Loebenberg, Erik Corcoran, Fred Menzel, Jr., Eugene L. Moss, Jr., Christine Norris, Monika Michalski, Kimberly Raynor, Judith Halpern, Cara Mendrick, Brian Arnold, Barry Antonacci, Raulo Parmegiani, Taisa Yarosh-Tomaine, George H. Miller, and Roberta S. Hare

In Vitro and In Vivo Activities of SCH 56592 (Posaconazole), a New Triazole Antifungal Agent, against Aspergillus and Candida
Antimicrob. Agents Chemother. 2000 44: 2017-2022. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Agnès Lefort, Michel Arthur, Louis Garry, Claude Carbon, Patrice Courvalin, and Bruno Fantin

Bactericidal Activity of Gentamicin against Enterococcus faecalis In Vitro and In Vivo
Antimicrob. Agents Chemother. 2000 44: 2077-2080. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Philippe Cottagnoud, Fernando Acosta, Marianne Cottagnoud, Klaus Neftel, and Martin G. Täuber

Synergy between Trovafloxacin and Ceftriaxone against Penicillin-Resistant Pneumococci in the Rabbit Meningitis Model and In Vitro
Antimicrob. Agents Chemother. 2000 44: 2179-2181. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Resistance:

Shizuko Iyobe, Haruko Kusadokoro, Junko Ozaki, Naoki Matsumura, Shinzaburo Minami, Shin Haruta, Tetsuo Sawai, and Koji O'Hara

Amino Acid Substitutions in a Variant of IMP-1 Metallo--Lactamase
Antimicrob. Agents Chemother. 2000 44: 2023-2027. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

L. K. Siu, J. Y. C. Lo, K. Y. Yuen, P. Y. Chau, M. H. Ng, and P. L. Ho

-Lactamases in Shigella flexneri Isolates from Hong Kong and Shanghai and a Novel OXA-1-Like -Lactamase, OXA-30
Antimicrob. Agents Chemother. 2000 44: 2034-2038. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Michael Korsinczky, Nanhua Chen, Barbara Kotecka, Allan Saul, Karl Rieckmann, and Qin Cheng

Mutations in Plasmodium falciparum Cytochrome b That Are Associated with Atovaquone Resistance Are Located at a Putative Drug-Binding Site
Antimicrob. Agents Chemother. 2000 44: 2100-2108. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

A. Tait-Kamradt, T. Davies, M. Cronan, M. R. Jacobs, P. C. Appelbaum, and J. Sutcliffe

Mutations in 23S rRNA and Ribosomal Protein L4 Account for Resistance in Pneumococcal Strains Selected In Vitro by Macrolide Passage
Antimicrob. Agents Chemother. 2000 44: 2118-2125. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Dong-Hyeon Kwon, Fouad A. K. El-Zaatari, Mototsugu Kato, Michael S. Osato, Rita Reddy, Yoshio Yamaoka, and David Y. Graham

Analysis of rdxA and Involvement of Additional Genes Encoding NAD(P)H Flavin Oxidoreductase (FrxA) and Ferredoxin-Like Protein (FdxB) in Metronidazole Resistance of Helicobacter pylori
Antimicrob. Agents Chemother. 2000 44: 2133-2142. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Beatriz Guerra, Sara Soto, Santiago Cal, and M. Carmen Mendoza

Antimicrobial Resistance and Spread of Class 1 Integrons among Salmonella Serotypes
Antimicrob. Agents Chemother. 2000 44: 2166-2169. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jesús Blazquez, María-Isabel Morosini, María-Cristina Negri, and Fernando Baquero

Selection of Naturally Occurring Extended-Spectrum TEM -Lactamase Variants by Fluctuating -Lactam Pressure
Antimicrob. Agents Chemother. 2000 44: 2182-2184. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

François Guerin, Emmanuelle Varon, Annie Buu Hoï, Laurent Gutmann, and Isabelle Podglajen

Fluoroquinolone Resistance Associated with Target Mutations and Active Efflux in Oropharyngeal Colonizing Isolates of Viridans Group Streptococci
Antimicrob. Agents Chemother. 2000 44: 2197-2200. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Patrice Nordmann, Laurent Poirel, Maryline Kubina, Anne Casetta, and Thierry Naas

Biochemical-Genetic Characterization and Distribution of OXA-22, a Chromosomal and Inducible Class D -Lactamase from Ralstonia (Pseudomonas) pickettii
Antimicrob. Agents Chemother. 2000 44: 2201-2204. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Nadia Maggi Solcà, Marco Valerio Bernasconi, and Jean-Claude Piffaretti

Mechanism of Metronidazole Resistance in Helicobacter pylori: Comparison of the rdxA Gene Sequences in 30 Strains
Antimicrob. Agents Chemother. 2000 44: 2207-2210. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Clinical Therapeutics:

H. Dupont and C. Carbon

Monotherapy with a Broad-Spectrum Beta-Lactam Is as Effective as Its Combination with an Aminoglycoside in Treatment of Severe Generalized Peritonitis: a Multicenter Randomized Controlled Trial
Antimicrob. Agents Chemother. 2000 44: 2028-2033. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Susceptibility:

Alexander M. Cole, Rabih O. Darouiche, Diana Legarda, Nancy Connell, and Gill Diamond

Characterization of a Fish Antimicrobial Peptide: Gene Expression, Subcellular Localization, and Spectrum of Activity
Antimicrob. Agents Chemother. 2000 44: 2039-2045. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

L. LaClaire and R. Facklam

Antimicrobial Susceptibilities and Clinical Sources of Facklamia Species
Antimicrob. Agents Chemother. 2000 44: 2130-2132. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

M. P. Singh, P. J. Petersen, W. J. Weiss, F. Kong, and M. Greenstein

Saccharomicins, Novel Heptadecaglycoside Antibiotics Produced by Saccharothrix espanaensis: Antibacterial and Mechanistic Activities
Antimicrob. Agents Chemother. 2000 44: 2154-2159. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

M. T. García, C. Pelaz, M. J. Giménez, and L. Aguilar

In Vitro Activities of Gemifloxacin versus Five Quinolones and Two Macrolides against 271 Spanish Isolates of Legionella pneumophila: Influence of Charcoal on Susceptibility Test Results
Antimicrob. Agents Chemother. 2000 44: 2176-2178. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Yuka Nakamura, Rui Kano, Tae Murai, Shinichi Watanabe, and Atsuhiko Hasegawa

Susceptibility Testing of Malassezia Species Using the Urea Broth Microdilution Method
Antimicrob. Agents Chemother. 2000 44: 2185-2186. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

E. J. Giamarellos-Bourboulis, P. Grecka, A. Dionyssiou-Asteriou, and H. Giamarellou

Impact of n-6 Polyunsaturated Fatty Acids on Growth of Multidrug-Resistant Pseudomonas aeruginosa: Interactions with Amikacin and Ceftazidime
Antimicrob. Agents Chemother. 2000 44: 2187-2189. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

S. Espuelas, P. Legrand, P. M. Loiseau, C. Bories, G. Barratt, and J. M. Irache

In Vitro Reversion of Amphotericin B Resistance in Leishmania donovani by Poloxamer 188
Antimicrob. Agents Chemother. 2000 44: 2190-2192. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Shirlena Wee-Ling Soh, Chit Laa Poh, and Raymond V. Tzer Pin Lin

Serotype Distribution and Antimicrobial Resistance of Streptococcus pneumoniae Isolates from Pediatric Patients in Singapore
Antimicrob. Agents Chemother. 2000 44: 2193-2196. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Barbara Heinemann, Hilmar Wisplinghoff, Michael Edmond, and Harald Seifert

Comparative Activities of Ciprofloxacin, Clinafloxacin, Gatifloxacin, Gemifloxacin, Levofloxacin, Moxifloxacin, and Trovafloxacin against Epidemiologically Defined Acinetobacter baumannii Strains
Antimicrob. Agents Chemother. 2000 44: 2211-2213. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mototsugu Kato, Yoshio Yamaoka, Jae J. Kim, Rita Reddy, Masahiro Asaka, Kei Kashima, Michael S. Osato, Fouad A. K. El-Zaatari, David Y. Graham, and Dong H. Kwon

Regional Differences in Metronidazole Resistance and Increasing Clarithromycin Resistance among Helicobacter pylori Isolates from Japan
Antimicrob. Agents Chemother. 2000 44: 2214-2216. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jennifer S. Daly, Theodore J. Giehl, Neal C. Brown, Chengxin Zhi, George E. Wright, and Richard T. Ellison, III

In Vitro Antimicrobial Activities of Novel Anilinouracils Which Selectively Inhibit DNA Polymerase III of Gram-Positive Bacteria
Antimicrob. Agents Chemother. 2000 44: 2217-2221. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hannah M. Wexler, Denise Molitoris, and Sydney M. Finegold

In Vitro Activities of MK-826 (L-749,345) against 363 Strains of Anaerobic Bacteria
Antimicrob. Agents Chemother. 2000 44: 2222-2224. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Helen W. Boucher, Christine B. Wennersten, and George M. Eliopoulos

In Vitro Activities of the Glycylcycline GAR-936 against Gram-Positive Bacteria
Antimicrob. Agents Chemother. 2000 44: 2225-2229. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pharmacology:

G. L. Drusano, S. L. Preston, M. Van Guilder, D. North, M. Gombert, M. Oefelein, L. Boccumini, B. Weisinger, M. Corrado, and J. Kahn

A Population Pharmacokinetic Analysis of the Penetration of the Prostate by Levofloxacin
Antimicrob. Agents Chemother. 2000 44: 2046-2051. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Thomas J. Walsh, Andre J. Jackson, James W. Lee, Michael Amantea, Tin Sein, John Bacher, and Loren Zech

Dose-Dependent Pharmacokinetics of Amphotericin B Lipid Complex in Rabbits
Antimicrob. Agents Chemother. 2000 44: 2068-2076. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Dennis M. Grasela, Randall R. Stoltz, Michael Barry, Michael Bone, Bernhard Mangold, Padraig O'Grady, Ralph Raymond, and Stephen J. Haworth

Pharmacokinetics of Single-Dose Oral Stavudine in Subjects with Renal Impairment and in Subjects Requiring Hemodialysis
Antimicrob. Agents Chemother. 2000 44: 2149-2153. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

M. Kelli Jordan, Michael A. Polis, Grace Kelly, Prem K. Narang, Henry Masur, and Stephen C. Piscitelli

Effects of Fluconazole and Clarithromycin on Rifabutin and 25-O-Desacetylrifabutin Pharmacokinetics
Antimicrob. Agents Chemother. 2000 44: 2170-2172. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Scott L. Letendre, Edmund V. Capparelli, Ronald J. Ellis, J. Allen McCutchan, and The HIV NEUROBEHAVIORAL RESEARCH CENTER GROUP

Indinavir Population Pharmacokinetics in Plasma and Cerebrospinal Fluid
Antimicrob. Agents Chemother. 2000 44: 2173-2175. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Zhi-Dong Jiang, Shi Ke, Ernesto Palazzini, Lise Riopel, and Herbert Dupont

In Vitro Activity and Fecal Concentration of Rifaximin after Oral Administration
Antimicrob. Agents Chemother. 2000 44: 2205-2206. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Antiviral Agents:

Stephen Weller, Kristine M. Radomski, Yu Lou, and Daniel S. Stein

Population Pharmacokinetics and Pharmacodynamic Modeling of Abacavir (1592U89) from a Dose-Ranging, Double-Blind, Randomized Monotherapy Trial with Human Immunodeficiency Virus-Infected Subjects
Antimicrob. Agents Chemother. 2000 44: 2052-2060. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

James A. McDowell, Yu Lou, William S. Symonds, and Daniel S. Stein

Multiple-Dose Pharmacokinetics and Pharmacodynamics of Abacavir Alone and in Combination with Zidovudine in Human Immunodeficiency Virus-Infected Adults
Antimicrob. Agents Chemother. 2000 44: 2061-2067. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Brett S. Robinson, Keith A. Riccardi, Yi-fei Gong, Qi Guo, David A. Stock, Wade S. Blair, Brian J. Terry, Carol A. Deminie, Fred Djang, Richard J. Colonno, and Pin-fang Lin

BMS-232632, a Highly Potent Human Immunodeficiency Virus Protease Inhibitor That Can Be Used in Combination with Other Available Antiretroviral Agents
Antimicrob. Agents Chemother. 2000 44: 2093-2099. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kristien Van Vaerenbergh, Kristel Van Laethem, Jan Albert, Charles A. B. Boucher, Bonaventura Clotet, Marco Floridia, Jan Gerstoft, Bo Hejdeman, Claus Nielsen, Christophe Pannecouque, Luc Perrin, Maria F. Pirillo, Lidia Ruiz, Jean-Claude Schmit, François Schneider, Anne Schoolmeester, Rob Schuurman, Hans J. Stellbrink, Lieven Stuyver, Jan Van Lunzen, Barbara Van Remoortel, Eric Van Wijngaerden, Stefano Vella, Myriam Witvrouw, Sabine Yerly, Erik De Clercq, Jan Desmyter, and Anne-Mieke Vandamme

Prevalence and Characteristics of Multinucleoside-Resistant Human Immunodeficiency Virus Type 1 among European Patients Receiving Combinations of Nucleoside Analogues
Antimicrob. Agents Chemother. 2000 44: 2109-2117. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mark M. Huycke, M. Tarek Naguib, Mathias M. Stroemmel, Kenneth Blick, Katherine Monti, Sarah Martin-Munley, and Chris Kaufman

A Double-Blind Placebo-Controlled Crossover Trial of Intravenous Magnesium Sulfate for Foscarnet-Induced Ionized Hypocalcemia and Hypomagnesemia in Patients with AIDS and Cytomegalovirus Infection
Antimicrob. Agents Chemother. 2000 44: 2143-2148. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Action:

Beth A. Arthington-Skaggs, David W. Warnock, and Christine J. Morrison

Quantitation of Candida albicans Ergosterol Content Improves the Correlation between In Vitro Antifungal Susceptibility Test Results and In Vivo Outcome after Fluconazole Treatment in a Murine Model of Invasive Candidiasis
Antimicrob. Agents Chemother. 2000 44: 2081-2085. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Carol L. Friedrich, Dianne Moyles, Terry J. Beveridge, and Robert E. W. Hancock

Antibacterial Action of Structurally Diverse Cationic Peptides on Gram-Positive Bacteria
Antimicrob. Agents Chemother. 2000 44: 2086-2092. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Katsuhiro Kawakami, Kenji Namba, Mayumi Tanaka, Norikazu Matsuhashi, Kenichi Sato, and Makoto Takemura

Antimycobacterial Activities of Novel Levofloxacin Analogues
Antimicrob. Agents Chemother. 2000 44: 2126-2129. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Bénédicte Fournier, Xilin Zhao, Tao Lu, Karl Drlica, and David C. Hooper

Selective Targeting of Topoisomerase IV and DNA Gyrase in Staphylococcus aureus: Different Patterns of Quinolone- Induced Inhibition of DNA Synthesis
Antimicrob. Agents Chemother. 2000 44: 2160-2165. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Letters:

Gioia S. Babini and David M. Livermore

Are SHV -Lactamases Universal in Klebsiella pneumoniae?
Antimicrob. Agents Chemother. 2000 44: 2230. [Full Text] [PDF] [Reprints and Permissions]  

Lars Bogø Jensen, Anette M. Hammerum, and Frank M. Aarestrup

Linkage of vat(E) and erm(B) in Streptogramin-Resistant Enterococcus faecium Isolates from Europe
Antimicrob. Agents Chemother. 2000 44: 2231-2232. [Full Text] [PDF] [Reprints and Permissions]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.