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Guest Commentary:

Arthur L. Koch

Autolysis Control Hypotheses for Tolerance to Wall Antibiotics
Antimicrob. Agents Chemother. 2001 45: 2671-2675. [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Resistance:

Sofia Perea, José L. López-Ribot, William R. Kirkpatrick, Robert K. McAtee, Rebecca A. Santillán, Marcos Martínez, David Calabrese, Dominique Sanglard, and Thomas F. Patterson

Prevalence of Molecular Mechanisms of Resistance to Azole Antifungal Agents in Candida albicans Strains Displaying High-Level Fluconazole Resistance Isolated from Human Immunodeficiency Virus-Infected Patients
Antimicrob. Agents Chemother. 2001 45: 2676-2684. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Joseph W. Chow, Vivek Kak, Il You, Susan J. Kao, Joanne Petrin, Don B. Clewell, Stephen A. Lerner, George H. Miller, and Karen J. Shaw

Aminoglycoside Resistance Genes aph(2")-Ib and aac(6')-Im Detected Together in Strains of both Escherichia coli and Enterococcus faecium
Antimicrob. Agents Chemother. 2001 45: 2691-2694. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

P. L. Winokur, D. L. Vonstein, L. J. Hoffman, E. K. Uhlenhopp, and G. V. Doern

Evidence for Transfer of CMY-2 AmpC -Lactamase Plasmids between Escherichia coli and Salmonella Isolates from Food Animals and Humans
Antimicrob. Agents Chemother. 2001 45: 2716-2722. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Dilek Ince and David C. Hooper

Mechanisms and Frequency of Resistance to Gatifloxacin in Comparison to AM-1121 and Ciprofloxacin in Staphylococcus aureus
Antimicrob. Agents Chemother. 2001 45: 2755-2764. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Katja E. Conrath, Marc Lauwereys, Moreno Galleni, André Matagne, Jean-Marie Frère, Jörg Kinne, Lode Wyns, and Serge Muyldermans

-Lactamase Inhibitors Derived from Single-Domain Antibody Fragments Elicited in the Camelidae
Antimicrob. Agents Chemother. 2001 45: 2807-2812. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

José Chaves, Margarita G. Ladona, Concepción Segura, Amparo Coira, Roser Reig, and Coral Ampurdanés

SHV-1 -Lactamase Is Mainly a Chromosomally Encoded Species-Specific Enzyme in Klebsiella pneumoniae
Antimicrob. Agents Chemother. 2001 45: 2856-2861. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sandra Hartman-Neumann, Kenneth DenBleyker, Lenore A. Pelosi, Laura E. Lawrence, John F. Barrett, and Thomas J. Dougherty

Selection and Genetic Characterization of Streptococcus pneumoniae Mutants Resistant to the Des-F(6) Quinolone BMS-284756
Antimicrob. Agents Chemother. 2001 45: 2865-2870. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Burkhard Springer, Yishak G. Kidan, Therdsak Prammananan, Kerstin Ellrott, Erik C. Böttger, and Peter Sander

Mechanisms of Streptomycin Resistance: Selection of Mutations in the 16S rRNA Gene Conferring Resistance
Antimicrob. Agents Chemother. 2001 45: 2877-2884. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Corinna Kehrenberg and Stefan Schwarz

Molecular Analysis of Tetracycline Resistance in Pasteurella aerogenes
Antimicrob. Agents Chemother. 2001 45: 2885-2890. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Thierry Naas, Sandrine Massuard, Fabien Garnier, and Patrice Nordmann

AmpD Is Required for Regulation of Expression of NmcA, a Carbapenem-Hydrolyzing -Lactamase of Enterobacter cloacae
Antimicrob. Agents Chemother. 2001 45: 2908-2915. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

S. Simjee, P. F. McDermott, D. D. Wagner, and D. G. White

Variation within the vat(E) Allele of Enterococcus faecium Isolates from Retail Poultry Samples
Antimicrob. Agents Chemother. 2001 45: 2931-2932. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Adam P. Roberts, Grace Cheah, Derren Ready, Jonathan Pratten, Michael Wilson, and Peter Mullany

Transfer of Tn916-Like Elements in Microcosm Dental Plaques
Antimicrob. Agents Chemother. 2001 45: 2943-2946. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hyunjoo Pai and George A. Jacoby

Sequences of the NPS-1 and TLE-1 -Lactamase Genes
Antimicrob. Agents Chemother. 2001 45: 2947-2948. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Luis Alou, Mario Ramirez, César García-Rey, José Prieto, and Hermínia de Lencastre

Streptococcus pneumoniae Isolates with Reduced Susceptibility to Ciprofloxacin in Spain: Clonal Diversity and Appearance of Ciprofloxacin-Resistant Epidemic Clones
Antimicrob. Agents Chemother. 2001 45: 2955-2957. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pio Maria Furneri, Giancarlo Rappazzo, Maria Pia Musumarra, Patrizia Di Pietro, Lucrezia S. Catania, and Lucia Silvana Roccasalva

Two New Point Mutations at A2062 Associated with Resistance to 16-Membered Macrolide Antibiotics in Mutant Strains of Mycoplasma hominis
Antimicrob. Agents Chemother. 2001 45: 2958-2960. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

E. D. J. Peters, M. A. Leverstein-van Hall, A. T. A. Box, J. Verhoef, and A. C. Fluit

Novel Gene Cassettes and Integrons
Antimicrob. Agents Chemother. 2001 45: 2961-2964. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Samuel Bellais, Laurent Poirel, Nicolas Fortineau, Jean W. Decousser, and Patrice Nordmann

Biochemical-Genetic Characterization of the Chromosomally Encoded Extended-Spectrum Class A -Lactamase from Rahnella aquatilis
Antimicrob. Agents Chemother. 2001 45: 2965-2968. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Experimental Therapeutics:

Paul H. Edelstein, F. Higa, and Martha A. C. Edelstein

In Vitro Activity of ABT-773 against Legionella pneumophila, Its Pharmacokinetics in Guinea Pigs, and Its Use to Treat Guinea Pigs with L. pneumophila Pneumonia
Antimicrob. Agents Chemother. 2001 45: 2685-2690. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

P. Aviles, C. Falcoz, M. J. Guillén, R. San Roman, F. Gómez De Las Heras, and D. Gargallo-Viola

Correlation between In Vitro and In Vivo Activities of GM 237354, a New Sordarin Derivative, against Candida albicans in an In Vitro Pharmacokinetic-Pharmacodynamic Model and Influence of Protein Binding
Antimicrob. Agents Chemother. 2001 45: 2746-2754. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Matthieu Lafaurie, Bruno Perichon, Agnes Lefort, Claude Carbon, Patrice Courvalin, and Bruno Fantin

Consequences of VanE-Type Resistance on Efficacy of Glycopeptides In Vitro and in Experimental Endocarditis Due to Enterococcus faecalis
Antimicrob. Agents Chemother. 2001 45: 2826-2830. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Andreas H. Groll, Diana Mickiene, Ruta Petraitiene, Vidmantas Petraitis, Caron A. Lyman, John S. Bacher, Stephen C. Piscitelli, and Thomas J. Walsh

Pharmacokinetic and Pharmacodynamic Modeling of Anidulafungin (LY303366): Reappraisal of Its Efficacy in Neutropenic Animal Models of Opportunistic Mycoses Using Optimal Plasma Sampling
Antimicrob. Agents Chemother. 2001 45: 2845-2855. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pedro Cravo, Richard Culleton, Paul Hunt, David Walliker, and Margaret J. Mackinnon

Antimalarial Drugs Clear Resistant Parasites from Partially Immune Hosts
Antimicrob. Agents Chemother. 2001 45: 2897-2901. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Alasdair P. MacGowan, Chris A. Rogers, H. Alan Holt, Mandy Wootton, and Karen E. Bowker

Pharmacodynamics of Gemifloxacin against Streptococcus pneumoniae in an In Vitro Pharmacokinetic Model of Infection
Antimicrob. Agents Chemother. 2001 45: 2916-2921. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Gigi H. Ross, Laurie Baeker Hovde, Khalid H. Ibrahim, Yasir H. Ibrahim, and John C. Rotschafer

Comparison of Once-Daily versus Twice-Daily Administration of Cefdinir against Typical Bacterial Respiratory Tract Pathogens
Antimicrob. Agents Chemother. 2001 45: 2936-2938. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Action:

Chengquan Zhao, Tung Nguyen, Lee Ming Boo, Teresa Hong, Cesar Espiritu, Dmitri Orlov, Wei Wang, Alan Waring, and Robert I. Lehrer

RL-37, an Alpha-Helical Antimicrobial Peptide of the Rhesus Monkey
Antimicrob. Agents Chemother. 2001 45: 2695-2702. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Tao Lu, Xilin Zhao, Xinying Li, Alex Drlica-Wagner, Jian-Ying Wang, John Domagala, and Karl Drlica

Enhancement of Fluoroquinolone Activity by C-8 Halogen and Methoxy Moieties: Action against a Gyrase Resistance Mutant of Mycobacterium smegmatis and a Gyrase-Topoisomerase IV Double Mutant of Staphylococcus aureus
Antimicrob. Agents Chemother. 2001 45: 2703-2709. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

M. Clelia Ganoza and Michael C. Kiel

A Ribosomal ATPase Is a Target for Hygromycin B Inhibition on Escherichia coli Ribosomes
Antimicrob. Agents Chemother. 2001 45: 2813-2819. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Takahisa Imamura, Kenji Matsushita, James Travis, and Jan Potempa

Inhibition of Trypsin-Like Cysteine Proteinases (Gingipains) from Porphyromonas gingivalis by Tetracycline and Its Analogues
Antimicrob. Agents Chemother. 2001 45: 2871-2876. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Fiona E. Angrave and Simon V. Avery

Antioxidant Functions Required for Insusceptibility of Saccharomyces cerevisiae to Tetracycline Antibiotics
Antimicrob. Agents Chemother. 2001 45: 2939-2942. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pharmacology:

Alfred J. Saah, Gregory A. Winchell, Michael L. Nessly, Melissa A. Seniuk, Rand R. Rhodes, and Paul J. Deutsch

Pharmacokinetic Profile and Tolerability of Indinavir-Ritonavir Combinations in Healthy Volunteers
Antimicrob. Agents Chemother. 2001 45: 2710-2715. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

P. Aviles, A. Pateman, R. San Roman, M. J. Guillén, F. Gómez De Las Heras, and D. Gargallo-Viola

Animal Pharmacokinetics and Interspecies Scaling of Sordarin Derivatives following Intravenous Administration
Antimicrob. Agents Chemother. 2001 45: 2787-2792. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

H. Abdelghaffar, D. Vazifeh, and M. T. Labro

Cellular Uptake of Two Fluoroketolides, HMR 3562 and HMR 3787, by Human Polymorphonuclear Neutrophils In Vitro
Antimicrob. Agents Chemother. 2001 45: 2798-2806. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

John E. Conte, Jr., Jeffrey A. Golden, Juliana Kipps, Emil T. Lin, and Elisabeth Zurlinden

Effects of AIDS and Gender on Steady-State Plasma and Intrapulmonary Ethambutol Concentrations
Antimicrob. Agents Chemother. 2001 45: 2891-2896. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Rieneke M. E. van Praag, Sjoerd Repping, Jan W. A. de Vries, Joep M. A. Lange, Richard M. W. Hoetelmans, and Jan M. Prins

Pharmacokinetic Profiles of Nevirapine and Indinavir in Various Fractions of Seminal Plasma
Antimicrob. Agents Chemother. 2001 45: 2902-2907. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Soichiro Kanoh, Jun Tamaoki, Mitsuko Kondo, Yuko Nagano, and Atsushi Nagai

Effects of New Quinolones on Transepithelial Electrical Potential Difference of Tracheal Mucosa In Vivo
Antimicrob. Agents Chemother. 2001 45: 2928-2930. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Rebecca S. Malone, Douglas N. Fish, Edward Abraham, and Isaac Teitelbaum

Pharmacokinetics of Levofloxacin and Ciprofloxacin during Continuous Renal Replacement Therapy in Critically Ill Patients
Antimicrob. Agents Chemother. 2001 45: 2949-2954. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Antiviral Agents:

Elena A. Govorkova, Irina A. Leneva, Olga G. Goloubeva, Karen Bush, and Robert G. Webster

Comparison of Efficacies of RWJ-270201, Zanamivir, and Oseltamivir against H5N1, H9N2, and Other Avian Influenza Viruses
Antimicrob. Agents Chemother. 2001 45: 2723-2732. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Patricia Barditch-Crovo, Steven G. Deeks, Ann Collier, Sharon Safrin, Dion F. Coakley, Michael Miller, Brian P. Kearney, Rebecca L. Coleman, Patrick D. Lamy, James O. Kahn, Ian McGowan, and Paul S. Lietman

Phase I/II Trial of the Pharmacokinetics, Safety, and Antiretroviral Activity of Tenofovir Disoproxil Fumarate in Human Immunodeficiency Virus-Infected Adults
Antimicrob. Agents Chemother. 2001 45: 2733-2739. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

John M. Cullen, Daniel H. Li, Cynthia Brown, Eugene J. Eisenberg, Kenneth C. Cundy, Julie Wolfe, Jay Toole, and Craig Gibbs

Antiviral Efficacy and Pharmacokinetics of Oral Adefovir Dipivoxil in Chronically Woodchuck Hepatitis Virus-Infected Woodchucks
Antimicrob. Agents Chemother. 2001 45: 2740-2745. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Edward P. Acosta and Henry H. Balfour, Jr.

Acyclovir for Treatment of Postherpetic Neuralgia: Efficacy and Pharmacokinetics
Antimicrob. Agents Chemother. 2001 45: 2771-2774. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Nell S. Lurain, Adriana Weinberg, Clyde S. Crumpacker, and Sunwen Chou

Sequencing of Cytomegalovirus UL97 Gene for Genotypic Antiviral Resistance Testing
Antimicrob. Agents Chemother. 2001 45: 2775-2780. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

James J. McSharry, Ann McDonough, Betty Olson, Sabine Hallenberger, Juergen Reefschlaeger, Wolfgang Bender, and George L. Drusano

Susceptibilities of Human Cytomegalovirus Clinical Isolates to BAY38-4766, BAY43-9695, and Ganciclovir
Antimicrob. Agents Chemother. 2001 45: 2925-2927. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Susceptibility:

Susan S. Chiu, Pak Leung Ho, Frankie K. H. Chow, Kwok Yung Yuen, and Yu Lung Lau

Nasopharyngeal Carriage of Antimicrobial-Resistant Streptococcus pneumoniae among Young Children Attending 79 Kindergartens and Day Care Centers in Hong Kong
Antimicrob. Agents Chemother. 2001 45: 2765-2770. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Luis Ostrosky-Zeichner, Scott Bazemore, Victor L. Paetznick, Jose R. Rodriguez, Enuo Chen, Tom Wallace, Paul Cossum, and John H. Rex

Differential Antifungal Activity of Isomeric Forms of Nystatin
Antimicrob. Agents Chemother. 2001 45: 2781-2786. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Yin Hoe Yau, Bow Ho, Nguan Soon Tan, Miang Lon Ng, and Jeak Ling Ding

High Therapeutic Index of Factor C Sushi Peptides: Potent Antimicrobials against Pseudomonas aeruginosa
Antimicrob. Agents Chemother. 2001 45: 2820-2825. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

David M. Livermore, Karen J. Oakton, Michael W. Carter, and Marina Warner

Activity of Ertapenem (MK-0826) versus Enterobacteriaceae with Potent -Lactamases
Antimicrob. Agents Chemother. 2001 45: 2831-2837. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Lisa Saiman, Setareh Tabibi, Timothy D. Starner, Pablo San Gabriel, Patricia L. Winokur, Hong Peng Jia, Paul B. McCray, Jr., and Brian F. Tack

Cathelicidin Peptides Inhibit Multiply Antibiotic-Resistant Pathogens from Patients with Cystic Fibrosis
Antimicrob. Agents Chemother. 2001 45: 2838-2844. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

M. A. Pfaller, S. A. Messer, R. J. Hollis, and R. N. Jones

In Vitro Activities of Posaconazole (Sch 56592) Compared with Those of Itraconazole and Fluconazole against 3,685 Clinical Isolates of Candida spp. and Cryptococcus neoformans
Antimicrob. Agents Chemother. 2001 45: 2862-2864. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Arthur L. Barry, Peter C. Fuchs, and Steven D. Brown

In Vitro Activity of the Ketolide ABT-773
Antimicrob. Agents Chemother. 2001 45: 2922-2924. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

A. Lozniewski, R. Labia, X. Haristoy, and F. Mory

Antimicrobial Susceptibilities of Clinical Desulfovibrio Isolates
Antimicrob. Agents Chemother. 2001 45: 2933-2935. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Clinical Therapeutics:

Paul G. Ambrose, Dennis M. Grasela, Thaddeus H. Grasela, Julie Passarell, Howard B. Mayer, and Phillip F. Pierce

Pharmacodynamics of Fluoroquinolones against Streptococcus pneumoniae in Patients with Community-Acquired Respiratory Tract Infections
Antimicrob. Agents Chemother. 2001 45: 2793-2797. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Letters:

Pilu Dali, Edmund R. Giugliano, Ernestine M. Vellozzi, and Miriam A. Smith

Susceptibilities of Propionibacterium acnes Ophthalmic Isolates to Moxifloxacin
Antimicrob. Agents Chemother. 2001 45: 2969-2970. [Full Text] [PDF] [Reprints and Permissions]  

Guillaume Arlet, David Nadjar, Jean-Louis Herrmann, Jean-Luc Donay, Martine Rouveau, Philippe H. Lagrange, and Alain Philippon

Plasmid-Mediated Rifampin Resistance Encoded by an arr-2-Like Gene Cassette in Klebsiella pneumoniae Producing an ACC-1 Class C -Lactamase
Antimicrob. Agents Chemother. 2001 45: 2971-2972. [Full Text] [PDF] [Reprints and Permissions]  

L. V. Stamm, H. L. Bergen, and K. A. Shangraw

Natural Rifampin Resistance in Treponema spp. Correlates with Presence of N531 in RpoB Rif Cluster I
Antimicrob. Agents Chemother. 2001 45: 2973-2974. [Full Text] [PDF] [Reprints and Permissions]  

R. G. J. Pot, J. G. Kusters, L. C. Smeets, W. Van Tongeren, C. M. J. E. Vandenbroucke-Grauls, and A. Bart

Interspecies Transfer of Antibiotic Resistance between Helicobacter pylori and Helicobacter acinonychis
Antimicrob. Agents Chemother. 2001 45: 2975-2976. [Full Text] [PDF] [Reprints and Permissions]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.