Contents: October 2001, Volume 45, Issue 10        Guest Commentary        Mechanisms of Resistance        Experimental Therapeutics        Mechanisms of Action        Pharmacology        Antiviral Agents        Susceptibility        Clinical Therapeutics        Letters Other Issues

Table of Contents

[Index by Author]

To see an article, click its [Full Text], [Abstract] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

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Guest Commentary:

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Autolysis Control Hypotheses for Tolerance to Wall Antibiotics Arthur L. Koch Antimicrob. Agents Chemother. October 2001 45: 2671-2675; [Full Text] [PDF] [Reprints and Permissions]

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Mechanisms of Resistance:

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Prevalence of Molecular Mechanisms of Resistance to Azole Antifungal Agents in Candida albicans Strains Displaying High-Level Fluconazole Resistance Isolated from Human Immunodeficiency Virus-Infected Patients Sofia Perea, José L. López-Ribot, William R. Kirkpatrick, Robert K. McAtee, Rebecca A. Santillán, Marcos Martínez, David Calabrese, Dominique Sanglard, and Thomas F. Patterson Antimicrob. Agents Chemother. October 2001 45: 2676-2684; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Aminoglycoside Resistance Genes aph(2")-Ib and aac(6')-Im Detected Together in Strains of both Escherichia coli and Enterococcus faecium Joseph W. Chow, Vivek Kak, Il You, Susan J. Kao, Joanne Petrin, Don B. Clewell, Stephen A. Lerner, George H. Miller, and Karen J. Shaw Antimicrob. Agents Chemother. October 2001 45: 2691-2694; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Evidence for Transfer of CMY-2 AmpC -Lactamase Plasmids between Escherichia coli and Salmonella Isolates from Food Animals and Humans P. L. Winokur, D. L. Vonstein, L. J. Hoffman, E. K. Uhlenhopp, and G. V. Doern Antimicrob. Agents Chemother. October 2001 45: 2716-2722; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mechanisms and Frequency of Resistance to Gatifloxacin in Comparison to AM-1121 and Ciprofloxacin in Staphylococcus aureus Dilek Ince and David C. Hooper Antimicrob. Agents Chemother. October 2001 45: 2755-2764; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

-Lactamase Inhibitors Derived from Single-Domain Antibody Fragments Elicited in the Camelidae Katja E. Conrath, Marc Lauwereys, Moreno Galleni, André Matagne, Jean-Marie Frère, Jörg Kinne, Lode Wyns, and Serge Muyldermans Antimicrob. Agents Chemother. October 2001 45: 2807-2812; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

SHV-1 -Lactamase Is Mainly a Chromosomally Encoded Species-Specific Enzyme in Klebsiella pneumoniae José Chaves, Margarita G. Ladona, Concepción Segura, Amparo Coira, Roser Reig, and Coral Ampurdanés Antimicrob. Agents Chemother. October 2001 45: 2856-2861; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Selection and Genetic Characterization of Streptococcus pneumoniae Mutants Resistant to the Des-F(6) Quinolone BMS-284756 Sandra Hartman-Neumann, Kenneth DenBleyker, Lenore A. Pelosi, Laura E. Lawrence, John F. Barrett, and Thomas J. Dougherty Antimicrob. Agents Chemother. October 2001 45: 2865-2870; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mechanisms of Streptomycin Resistance: Selection of Mutations in the 16S rRNA Gene Conferring Resistance Burkhard Springer, Yishak G. Kidan, Therdsak Prammananan, Kerstin Ellrott, Erik C. Böttger, and Peter Sander Antimicrob. Agents Chemother. October 2001 45: 2877-2884; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Molecular Analysis of Tetracycline Resistance in Pasteurella aerogenes Corinna Kehrenberg and Stefan Schwarz Antimicrob. Agents Chemother. October 2001 45: 2885-2890; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

AmpD Is Required for Regulation of Expression of NmcA, a Carbapenem-Hydrolyzing -Lactamase of Enterobacter cloacae Thierry Naas, Sandrine Massuard, Fabien Garnier, and Patrice Nordmann Antimicrob. Agents Chemother. October 2001 45: 2908-2915; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Variation within the vat(E) Allele of Enterococcus faecium Isolates from Retail Poultry Samples S. Simjee, P. F. McDermott, D. D. Wagner, and D. G. White Antimicrob. Agents Chemother. October 2001 45: 2931-2932; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Transfer of Tn916-Like Elements in Microcosm Dental Plaques Adam P. Roberts, Grace Cheah, Derren Ready, Jonathan Pratten, Michael Wilson, and Peter Mullany Antimicrob. Agents Chemother. October 2001 45: 2943-2946; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Sequences of the NPS-1 and TLE-1 -Lactamase Genes Hyunjoo Pai and George A. Jacoby Antimicrob. Agents Chemother. October 2001 45: 2947-2948; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Streptococcus pneumoniae Isolates with Reduced Susceptibility to Ciprofloxacin in Spain: Clonal Diversity and Appearance of Ciprofloxacin-Resistant Epidemic Clones Luis Alou, Mario Ramirez, César García-Rey, José Prieto, and Hermínia de Lencastre Antimicrob. Agents Chemother. October 2001 45: 2955-2957; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Two New Point Mutations at A2062 Associated with Resistance to 16-Membered Macrolide Antibiotics in Mutant Strains of Mycoplasma hominis Pio Maria Furneri, Giancarlo Rappazzo, Maria Pia Musumarra, Patrizia Di Pietro, Lucrezia S. Catania, and Lucia Silvana Roccasalva Antimicrob. Agents Chemother. October 2001 45: 2958-2960; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Novel Gene Cassettes and Integrons E. D. J. Peters, M. A. Leverstein-van Hall, A. T. A. Box, J. Verhoef, and A. C. Fluit Antimicrob. Agents Chemother. October 2001 45: 2961-2964; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Biochemical-Genetic Characterization of the Chromosomally Encoded Extended-Spectrum Class A -Lactamase from Rahnella aquatilis Samuel Bellais, Laurent Poirel, Nicolas Fortineau, Jean W. Decousser, and Patrice Nordmann Antimicrob. Agents Chemother. October 2001 45: 2965-2968; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Experimental Therapeutics:

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In Vitro Activity of ABT-773 against Legionella pneumophila, Its Pharmacokinetics in Guinea Pigs, and Its Use to Treat Guinea Pigs with L. pneumophila Pneumonia Paul H. Edelstein, F. Higa, and Martha A. C. Edelstein Antimicrob. Agents Chemother. October 2001 45: 2685-2690; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Correlation between In Vitro and In Vivo Activities of GM 237354, a New Sordarin Derivative, against Candida albicans in an In Vitro Pharmacokinetic-Pharmacodynamic Model and Influence of Protein Binding P. Aviles, C. Falcoz, M. J. Guillén, R. San Roman, F. Gómez De Las Heras, and D. Gargallo-Viola Antimicrob. Agents Chemother. October 2001 45: 2746-2754; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Consequences of VanE-Type Resistance on Efficacy of Glycopeptides In Vitro and in Experimental Endocarditis Due to Enterococcus faecalis Matthieu Lafaurie, Bruno Perichon, Agnes Lefort, Claude Carbon, Patrice Courvalin, and Bruno Fantin Antimicrob. Agents Chemother. October 2001 45: 2826-2830; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pharmacokinetic and Pharmacodynamic Modeling of Anidulafungin (LY303366): Reappraisal of Its Efficacy in Neutropenic Animal Models of Opportunistic Mycoses Using Optimal Plasma Sampling Andreas H. Groll, Diana Mickiene, Ruta Petraitiene, Vidmantas Petraitis, Caron A. Lyman, John S. Bacher, Stephen C. Piscitelli, and Thomas J. Walsh Antimicrob. Agents Chemother. October 2001 45: 2845-2855; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antimalarial Drugs Clear Resistant Parasites from Partially Immune Hosts Pedro Cravo, Richard Culleton, Paul Hunt, David Walliker, and Margaret J. Mackinnon Antimicrob. Agents Chemother. October 2001 45: 2897-2901; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pharmacodynamics of Gemifloxacin against Streptococcus pneumoniae in an In Vitro Pharmacokinetic Model of Infection Alasdair P. MacGowan, Chris A. Rogers, H. Alan Holt, Mandy Wootton, and Karen E. Bowker Antimicrob. Agents Chemother. October 2001 45: 2916-2921; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Comparison of Once-Daily versus Twice-Daily Administration of Cefdinir against Typical Bacterial Respiratory Tract Pathogens Gigi H. Ross, Laurie Baeker Hovde, Khalid H. Ibrahim, Yasir H. Ibrahim, and John C. Rotschafer Antimicrob. Agents Chemother. October 2001 45: 2936-2938; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Mechanisms of Action:

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RL-37, an Alpha-Helical Antimicrobial Peptide of the Rhesus Monkey Chengquan Zhao, Tung Nguyen, Lee Ming Boo, Teresa Hong, Cesar Espiritu, Dmitri Orlov, Wei Wang, Alan Waring, and Robert I. Lehrer Antimicrob. Agents Chemother. October 2001 45: 2695-2702; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Enhancement of Fluoroquinolone Activity by C-8 Halogen and Methoxy Moieties: Action against a Gyrase Resistance Mutant of Mycobacterium smegmatis and a Gyrase-Topoisomerase IV Double Mutant of Staphylococcus aureus Tao Lu, Xilin Zhao, Xinying Li, Alex Drlica-Wagner, Jian-Ying Wang, John Domagala, and Karl Drlica Antimicrob. Agents Chemother. October 2001 45: 2703-2709; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

A Ribosomal ATPase Is a Target for Hygromycin B Inhibition on Escherichia coli Ribosomes M. Clelia Ganoza and Michael C. Kiel Antimicrob. Agents Chemother. October 2001 45: 2813-2819; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Inhibition of Trypsin-Like Cysteine Proteinases (Gingipains) from Porphyromonas gingivalis by Tetracycline and Its Analogues Takahisa Imamura, Kenji Matsushita, James Travis, and Jan Potempa Antimicrob. Agents Chemother. October 2001 45: 2871-2876; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antioxidant Functions Required for Insusceptibility of Saccharomyces cerevisiae to Tetracycline Antibiotics Fiona E. Angrave and Simon V. Avery Antimicrob. Agents Chemother. October 2001 45: 2939-2942; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Pharmacology:

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Pharmacokinetic Profile and Tolerability of Indinavir-Ritonavir Combinations in Healthy Volunteers Alfred J. Saah, Gregory A. Winchell, Michael L. Nessly, Melissa A. Seniuk, Rand R. Rhodes, and Paul J. Deutsch Antimicrob. Agents Chemother. October 2001 45: 2710-2715; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Animal Pharmacokinetics and Interspecies Scaling of Sordarin Derivatives following Intravenous Administration P. Aviles, A. Pateman, R. San Roman, M. J. Guillén, F. Gómez De Las Heras, and D. Gargallo-Viola Antimicrob. Agents Chemother. October 2001 45: 2787-2792; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Cellular Uptake of Two Fluoroketolides, HMR 3562 and HMR 3787, by Human Polymorphonuclear Neutrophils In Vitro H. Abdelghaffar, D. Vazifeh, and M. T. Labro Antimicrob. Agents Chemother. October 2001 45: 2798-2806; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Effects of AIDS and Gender on Steady-State Plasma and Intrapulmonary Ethambutol Concentrations John E. Conte, Jr., Jeffrey A. Golden, Juliana Kipps, Emil T. Lin, and Elisabeth Zurlinden Antimicrob. Agents Chemother. October 2001 45: 2891-2896; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pharmacokinetic Profiles of Nevirapine and Indinavir in Various Fractions of Seminal Plasma Rieneke M. E. van Praag, Sjoerd Repping, Jan W. A. de Vries, Joep M. A. Lange, Richard M. W. Hoetelmans, and Jan M. Prins Antimicrob. Agents Chemother. October 2001 45: 2902-2907; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Effects of New Quinolones on Transepithelial Electrical Potential Difference of Tracheal Mucosa In Vivo Soichiro Kanoh, Jun Tamaoki, Mitsuko Kondo, Yuko Nagano, and Atsushi Nagai Antimicrob. Agents Chemother. October 2001 45: 2928-2930; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pharmacokinetics of Levofloxacin and Ciprofloxacin during Continuous Renal Replacement Therapy in Critically Ill Patients Rebecca S. Malone, Douglas N. Fish, Edward Abraham, and Isaac Teitelbaum Antimicrob. Agents Chemother. October 2001 45: 2949-2954; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Antiviral Agents:

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Comparison of Efficacies of RWJ-270201, Zanamivir, and Oseltamivir against H5N1, H9N2, and Other Avian Influenza Viruses Elena A. Govorkova, Irina A. Leneva, Olga G. Goloubeva, Karen Bush, and Robert G. Webster Antimicrob. Agents Chemother. October 2001 45: 2723-2732; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Phase I/II Trial of the Pharmacokinetics, Safety, and Antiretroviral Activity of Tenofovir Disoproxil Fumarate in Human Immunodeficiency Virus-Infected Adults Patricia Barditch-Crovo, Steven G. Deeks, Ann Collier, Sharon Safrin, Dion F. Coakley, Michael Miller, Brian P. Kearney, Rebecca L. Coleman, Patrick D. Lamy, James O. Kahn, Ian McGowan, and Paul S. Lietman Antimicrob. Agents Chemother. October 2001 45: 2733-2739; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antiviral Efficacy and Pharmacokinetics of Oral Adefovir Dipivoxil in Chronically Woodchuck Hepatitis Virus-Infected Woodchucks John M. Cullen, Daniel H. Li, Cynthia Brown, Eugene J. Eisenberg, Kenneth C. Cundy, Julie Wolfe, Jay Toole, and Craig Gibbs Antimicrob. Agents Chemother. October 2001 45: 2740-2745; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Acyclovir for Treatment of Postherpetic Neuralgia: Efficacy and Pharmacokinetics Edward P. Acosta and Henry H. Balfour, Jr. Antimicrob. Agents Chemother. October 2001 45: 2771-2774; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Sequencing of Cytomegalovirus UL97 Gene for Genotypic Antiviral Resistance Testing Nell S. Lurain, Adriana Weinberg, Clyde S. Crumpacker, and Sunwen Chou Antimicrob. Agents Chemother. October 2001 45: 2775-2780; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Susceptibilities of Human Cytomegalovirus Clinical Isolates to BAY38-4766, BAY43-9695, and Ganciclovir James J. McSharry, Ann McDonough, Betty Olson, Sabine Hallenberger, Juergen Reefschlaeger, Wolfgang Bender, and George L. Drusano Antimicrob. Agents Chemother. October 2001 45: 2925-2927; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Susceptibility:

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Nasopharyngeal Carriage of Antimicrobial-Resistant Streptococcus pneumoniae among Young Children Attending 79 Kindergartens and Day Care Centers in Hong Kong Susan S. Chiu, Pak Leung Ho, Frankie K. H. Chow, Kwok Yung Yuen, and Yu Lung Lau Antimicrob. Agents Chemother. October 2001 45: 2765-2770; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Differential Antifungal Activity of Isomeric Forms of Nystatin Luis Ostrosky-Zeichner, Scott Bazemore, Victor L. Paetznick, Jose R. Rodriguez, Enuo Chen, Tom Wallace, Paul Cossum, and John H. Rex Antimicrob. Agents Chemother. October 2001 45: 2781-2786; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

High Therapeutic Index of Factor C Sushi Peptides: Potent Antimicrobials against Pseudomonas aeruginosa Yin Hoe Yau, Bow Ho, Nguan Soon Tan, Miang Lon Ng, and Jeak Ling Ding Antimicrob. Agents Chemother. October 2001 45: 2820-2825; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Activity of Ertapenem (MK-0826) versus Enterobacteriaceae with Potent -Lactamases David M. Livermore, Karen J. Oakton, Michael W. Carter, and Marina Warner Antimicrob. Agents Chemother. October 2001 45: 2831-2837; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Cathelicidin Peptides Inhibit Multiply Antibiotic-Resistant Pathogens from Patients with Cystic Fibrosis Lisa Saiman, Setareh Tabibi, Timothy D. Starner, Pablo San Gabriel, Patricia L. Winokur, Hong Peng Jia, Paul B. McCray, Jr., and Brian F. Tack Antimicrob. Agents Chemother. October 2001 45: 2838-2844; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activities of Posaconazole (Sch 56592) Compared with Those of Itraconazole and Fluconazole against 3,685 Clinical Isolates of Candida spp. and Cryptococcus neoformans M. A. Pfaller, S. A. Messer, R. J. Hollis, and R. N. Jones Antimicrob. Agents Chemother. October 2001 45: 2862-2864; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activity of the Ketolide ABT-773 Arthur L. Barry, Peter C. Fuchs, and Steven D. Brown Antimicrob. Agents Chemother. October 2001 45: 2922-2924; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antimicrobial Susceptibilities of Clinical Desulfovibrio Isolates A. Lozniewski, R. Labia, X. Haristoy, and F. Mory Antimicrob. Agents Chemother. October 2001 45: 2933-2935; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Clinical Therapeutics:

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Pharmacodynamics of Fluoroquinolones against Streptococcus pneumoniae in Patients with Community-Acquired Respiratory Tract Infections Paul G. Ambrose, Dennis M. Grasela, Thaddeus H. Grasela, Julie Passarell, Howard B. Mayer, and Phillip F. Pierce Antimicrob. Agents Chemother. October 2001 45: 2793-2797; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Letters:

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Susceptibilities of Propionibacterium acnes Ophthalmic Isolates to Moxifloxacin Pilu Dali, Edmund R. Giugliano, Ernestine M. Vellozzi, and Miriam A. Smith Antimicrob. Agents Chemother. October 2001 45: 2969-2970; [Full Text] [PDF] [Reprints and Permissions]

Plasmid-Mediated Rifampin Resistance Encoded by an arr-2-Like Gene Cassette in Klebsiella pneumoniae Producing an ACC-1 Class C -Lactamase Guillaume Arlet, David Nadjar, Jean-Louis Herrmann, Jean-Luc Donay, Martine Rouveau, Philippe H. Lagrange, and Alain Philippon Antimicrob. Agents Chemother. October 2001 45: 2971-2972; [Full Text] [PDF] [Reprints and Permissions]

Natural Rifampin Resistance in Treponema spp. Correlates with Presence of N531 in RpoB Rif Cluster I L. V. Stamm, H. L. Bergen, and K. A. Shangraw Antimicrob. Agents Chemother. October 2001 45: 2973-2974; [Full Text] [PDF] [Reprints and Permissions]

Interspecies Transfer of Antibiotic Resistance between Helicobacter pylori and Helicobacter acinonychis R. G. J. Pot, J. G. Kusters, L. C. Smeets, W. Van Tongeren, C. M. J. E. Vandenbroucke-Grauls, and A. Bart Antimicrob. Agents Chemother. October 2001 45: 2975-2976; [Full Text] [PDF] [Reprints and Permissions]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.