Contents: November 2001, Volume 45, Issue 11        Minireviews        Guest Commentary        Mechanisms of Resistance        Susceptibility        Antiviral Agents        Pharmacology        Analytical Procedures        Mechanisms of Action        Experimental Therapeutics        Clinical Therapeutics Other Issues

Table of Contents

[Index by Author]

To see an article, click its [Full Text], [Abstract] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

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Minireviews:

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Use of Aminoglycosides in Treatment of Infections Due to Intracellular Bacteria M. Maurin and D. Raoult Antimicrob. Agents Chemother. November 2001 45: 2977-2986; [Full Text] [PDF] [Reprints and Permissions]

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Guest Commentary:

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Critical Annotations to the Use of Azole Antifungals for Plant Protection Herbert Hof Antimicrob. Agents Chemother. November 2001 45: 2987-2990; [Full Text] [PDF] [Reprints and Permissions]

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Mechanisms of Resistance:

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Molecular Analysis of Antibiotic Resistance Gene Clusters in Vibrio cholerae O139 and O1 SXT Constins Bianca Hochhut, Yasmin Lotfi, Didier Mazel, Shah M. Faruque, Roger Woodgate, and Matthew K. Waldor Antimicrob. Agents Chemother. November 2001 45: 2991-3000; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Family of Class 1 Integrons Related to In4 from Tn1696 Sally R. Partridge, Gavin D. Recchia, H. W. Stokes, and Ruth M. Hall Antimicrob. Agents Chemother. November 2001 45: 3014-3020; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro and In Vivo Effects of 14-Demethylase (ERG11) Depletion in Candida glabrata Hironobu Nakayama, Noboru Nakayama, Mikio Arisawa, and Yuko Aoki Antimicrob. Agents Chemother. November 2001 45: 3037-3045; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Rifampin Resistance in Mycobacterium kansasii Is Associated with rpoB Mutations John L. Klein, Timothy J. Brown, and Gary L. French Antimicrob. Agents Chemother. November 2001 45: 3056-3058; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Role of Penicillin-Binding Protein 4 in Expression of Vancomycin Resistance among Clinical Isolates of Oxacillin-Resistant Staphylococcus aureus J. E. Finan, Gordon L. Archer, Michael J. Pucci, and Michael W. Climo Antimicrob. Agents Chemother. November 2001 45: 3070-3075; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Association of Genetic Mutations in Plasmodium vivax dhfr with Resistance to Sulfadoxine-Pyrimethamine: Geographical and Clinical Correlates Mallika Imwong, Sasithon Pukrittakayamee, Sornchai Looareesuwan, Geoffrey Pasvol, Jean Poirreiz, Nicholas J. White, and Georges Snounou Antimicrob. Agents Chemother. November 2001 45: 3122-3127; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Quinolone Resistance Mutations in Streptococcus pneumoniae GyrA and ParC Proteins: Mechanistic Insights into Quinolone Action from Enzymatic Analysis, Intracellular Levels, and Phenotypes of Wild-Type and Mutant Proteins Xiao-Su Pan, Genoveva Yague, and L. Mark Fisher Antimicrob. Agents Chemother. November 2001 45: 3140-3147; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Reversal of Chloroquine Resistance in Plasmodium falciparum Using Combinations of Chemosensitizers Donelly A. van Schalkwyk, Jason C. Walden, and Peter J. Smith Antimicrob. Agents Chemother. November 2001 45: 3171-3174; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Cloning and Biochemical Characterization of FOX-5, an AmpC-Type Plasmid-Encoded -Lactamase from a New York City Klebsiella pneumoniae Clinical Isolate Anne Marie Queenan, Stephen Jenkins, and Karen Bush Antimicrob. Agents Chemother. November 2001 45: 3189-3194; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Genetic Analysis of Multiple Loci Suggests that Mutations in the Pneumocystis carinii f. sp. hominis Dihydropteroate Synthase Gene Arose Independently in Multiple Strains Liang Ma and Joseph A. Kovacs Antimicrob. Agents Chemother. November 2001 45: 3213-3215; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Indication of Transposition of a Mobile DNA Element Containing the vat(D) and erm(B) Genes in Enterococcus faecium Anette M. Hammerum, Susan E. Flannagan, Don B. Clewell, and Lars Bogø Jensen Antimicrob. Agents Chemother. November 2001 45: 3223-3225; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Novel Tetracycline Resistance Gene, tet(32), in the Clostridium-Related Human Colonic Anaerobe K10 and Its Transmission In Vitro to the Rumen Anaerobe Butyrivibrio fibrisolvens Claire M. Melville, Karen P. Scott, Derry K. Mercer, and Harry J. Flint Antimicrob. Agents Chemother. November 2001 45: 3246-3249; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Aminoglycoside-Streptothricin Resistance Gene Cluster aadE-sat4-aphA-3 Disseminated among Multiresistant Isolates of Enterococcus faecium Guido Werner, Bianca Hildebrandt, and Wolfgang Witte Antimicrob. Agents Chemother. November 2001 45: 3267-3269; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Staphylococcus aureus Mutants Selected by BMS-284756 L. F. Discotto, L. E. Lawrence, K. L. Denbleyker, and J. F. Barrett Antimicrob. Agents Chemother. November 2001 45: 3273-3275; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Susceptibility:

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Effects of Azithromycin and Rifampin on Chlamydia trachomatis Infection In Vitro Ute Dreses-Werringloer, Ingrid Padubrin, Henning Zeidler, and Lars Köhler Antimicrob. Agents Chemother. November 2001 45: 3001-3008; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Antimicrobial Activities of Bakuchiol against Oral Microorganisms Harumi Katsura, Ryo-Ichi Tsukiyama, Akiko Suzuki, and Makio Kobayashi Antimicrob. Agents Chemother. November 2001 45: 3009-3013; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Trends in Antifungal Drug Susceptibility of Cryptococcus neoformans Isolates in the United States: 1992 to 1994 and 1996 to 1998 Mary E. Brandt, Michael A. Pfaller, Rana A. Hajjeh, Richard J. Hamill, Peter G. Pappas, Arthur L. Reingold, David Rimland, and David W. Warnock Antimicrob. Agents Chemother. November 2001 45: 3065-3069; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Emergence of Reduced Susceptibility and Resistance to Fluoroquinolones in Escherichia coli in Taiwan and Contributions of Distinct Selective Pressures L. Clifford McDonald, Feng-Jui Chen, Hsiu-Jung Lo, Hsiao-Chuan Yin, Po-Liang Lu, Cheng-Hua Huang, Pei Chen, Tsai-Ling Lauderdale, and Monto Ho Antimicrob. Agents Chemother. November 2001 45: 3084-3091; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antibacterial Activities and Pharmacokinetics of E-4767 and E-5065, Two New 8-Chlorofluoroquinolones with a 7-Azetidin Ring Substituent Domingo Gargallo-Viola, Santiago Ferrer, Encarna Tudela, Marta Robert, Ramon Coll, Roberto Roser, and Jesus Guinea Antimicrob. Agents Chemother. November 2001 45: 3113-3121; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antifungal Activities and Cytotoxicity Studies of Six New Azasordarins Esperanza Herreros, Maria Jesus Almela, Sonia Lozano, Federico Gomez De Las Heras, and Domingo Gargallo-Viola Antimicrob. Agents Chemother. November 2001 45: 3132-3139; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Anti-Helicobacter pylori Activity of the Probiotic Strain Bacillus subtilis 3 Is Due to Secretion of Antibiotics Irina V. Pinchuk, Philippe Bressollier, Bernard Verneuil, Bernard Fenet, Irina B. Sorokulova, Francis Mégraud, and Maria C. Urdaci Antimicrob. Agents Chemother. November 2001 45: 3156-3161; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Analysis of Antimalarial Synergy between Bestatin and Endoprotease Inhibitors Using Statistical Response-Surface Modelling Clare S. Gavigan, Stella G. Machado, John P. Dalton, and Angus Bell Antimicrob. Agents Chemother. November 2001 45: 3175-3181; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Marked Potentiation of Activity of -Lactams against Methicillin-Resistant Staphylococcus aureus by Corilagin Masato Shimizu, Sumiko Shiota, Tohru Mizushima, Hideyuki Ito, Tsutomu Hatano, Takashi Yoshida, and Tomofusa Tsuchiya Antimicrob. Agents Chemother. November 2001 45: 3198-3201; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

High Incidence of Erythromycin Resistance among Clinical Isolates of Streptococcus agalactiae in Taiwan Po-Ren Hsueh, Lee-Jene Teng, Li-Na Lee, Shen-Wu Ho, Pan-Chyr Yang, and Kwen-Tay Luh Antimicrob. Agents Chemother. November 2001 45: 3205-3208; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Killing of Candida albicans by Fatty Acids and Monoglycerides Gudmundur Bergsson, Jóhann Arnfinnsson, Ólafur Steingrímsson, and Halldor Thormar Antimicrob. Agents Chemother. November 2001 45: 3209-3212; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Susceptibilities of Oral Bacteria and Yeast to Mammalian Cathelicidins Janet M. Guthmiller, Kaaren G. Vargas, Rupasree Srikantha, Lori L. Schomberg, Paula L. Weistroffer, Paul B. McCray, Jr., and Brian F. Tack Antimicrob. Agents Chemother. November 2001 45: 3216-3219; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Synergistic Activities of Gatifloxacin in Combination with Other Antimicrobial Agents against Pseudomonas aeruginosa and Related Species Elizabeth Gradelski, Lourdes Valera, Daniel Bonner, and Joan Fung-Tomc Antimicrob. Agents Chemother. November 2001 45: 3220-3222; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antimicrobial Susceptibilities of 1,730 Haemophilus influenzae Respiratory Tract Isolates in Spain in 1998-1999 Francesc Marco, Juan García-de-Lomas, César García-Rey, Emilio Bouza, Lorenzo Aguilar, and Carlos Fernández-Mazarrasa Antimicrob. Agents Chemother. November 2001 45: 3226-3228; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Activities of a New Fluoroketolide, HMR 3787, and Its (Des)-Fluor Derivative RU 64399 Compared to Those of Telithromycin, Erythromycin A, Azithromycin, Clarithromycin, and Clindamycin against Macrolide-Susceptible or -Resistant Streptococcus pneumoniae and S. pyogenes Kensuke Nagai, Todd A. Davies, Lois M. Ednie, Andre Bryskier, Elizabeth Palavecino, Michael R. Jacobs, and Peter C. Appelbaum Antimicrob. Agents Chemother. November 2001 45: 3242-3245; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Susceptibilities of Eikenella corrodens, Prevotella intermedia, and Prevotella nigrescens Clinical Isolates to Amoxicillin and Tetracycline N. Luong, J. Tsai, and C. Chen Antimicrob. Agents Chemother. November 2001 45: 3253-3255; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro and In Vivo Activities of Sitafloxacin against Chlamydia spp. Naoyuki Miyashita, Yoshihito Niki, and Toshiharu Matsushima Antimicrob. Agents Chemother. November 2001 45: 3270-3272; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Susceptibility of Coxiella burnetii to Linezolid in Comparison with Its Susceptibilities to Quinolones, Doxycycline, and Clarithromycin Achilleas Gikas, Ioanna Spyridaki, Efstathia Scoulica, Anna Psaroulaki, and Yannis Tselentis Antimicrob. Agents Chemother. November 2001 45: 3276-3278; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Antiviral Agents:

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DPC 681 and DPC 684: Potent, Selective Inhibitors of Human Immunodeficiency Virus Protease Active against Clinically Relevant Mutant Variants Robert F. Kaltenbach, III, George Trainor, Daniel Getman, Greg Harris, Sena Garber, Beverly Cordova, Lee Bacheler, Susan Jeffrey, Kelly Logue, Pamela Cawood, Ronald Klabe, Sharon Diamond, Marc Davies, Joanne Saye, Janan Jona, and Susan Erickson-Viitanen Antimicrob. Agents Chemother. November 2001 45: 3021-3028; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Pharmacology:

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Development and Validation of Limited-Sampling Strategies for Predicting Amoxicillin Pharmacokinetic and Pharmacodynamic Parameters Guilherme Suarez-Kurtz, Frederico Mota Ribeiro, Flávio L. Vicente, and Claudio J. Struchiner Antimicrob. Agents Chemother. November 2001 45: 3029-3036; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Bronchopulmonary Disposition of the Ketolide Telithromycin (HMR 3647) Claudette Muller-Serieys, Paul Soler, Cathy Cantalloube, Françoise Lemaitre, Hai Pham Gia, Françoise Brunner, and Antoine Andremont Antimicrob. Agents Chemother. November 2001 45: 3104-3108; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pharmacokinetics of Cefepime during Continuous Renal Replacement Therapy in Critically Ill Patients Rebecca S. Malone, Douglas N. Fish, Edward Abraham, and Isaac Teitelbaum Antimicrob. Agents Chemother. November 2001 45: 3148-3155; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Rifampin Reduces Concentrations of Trimethoprim and Sulfamethoxazole in Serum in Human Immunodeficiency Virus-Infected Patients Esteban Ribera, Leonor Pou, Antoni Fernandez-Sola, Francisco Campos, Rosa M. Lopez, Imma Ocaña, Isabel Ruiz, and Albert Pahissa Antimicrob. Agents Chemother. November 2001 45: 3238-3241; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Analytical Procedures:

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Single Ribosomal Protein Mutations in Antibiotic-Resistant Bacteria Analyzed by Mass Spectrometry Sheri K. Wilcox, Gregory S. Cavey, and James D. Pearson Antimicrob. Agents Chemother. November 2001 45: 3046-3055; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Mechanisms of Action:

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Clearance of Infection with Mycobacterium bovis BCG in Mice Is Enhanced by Treatment with S28463 (R-848), and Its Efficiency Depends on Expression of Wild-Type Nramp1 (Resistance Allele) Jacques Moisan, Wojciech Wojciechowski, Claudine Guilbault, Claude Lachance, Sergio Di Marco, Emil Skamene, Greg Matlashewski, and Danuta Radzioch Antimicrob. Agents Chemother. November 2001 45: 3059-3064; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

ATP Synthase Is Necessary for Microcin H47 Antibiotic Action Mónica Trujillo, Eliana Rodríguez, and Magela Laviña Antimicrob. Agents Chemother. November 2001 45: 3128-3131; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Rapamycin and Less Immunosuppressive Analogs Are Toxic to Candida albicans and Cryptococcus neoformans via FKBP12-Dependent Inhibition of TOR M. Cristina Cruz, Alan L. Goldstein, Jill Blankenship, Maurizio Del Poeta, John R. Perfect, John H. McCusker, Youssef L. Bennani, Maria E. Cardenas, and Joseph Heitman Antimicrob. Agents Chemother. November 2001 45: 3162-3170; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Identification and Characterization of New Inhibitors of the Escherichia coli MurA Enzyme Ellen Z. Baum, Deborah A. Montenegro, Lisa Licata, Ignatius Turchi, Glenda C. Webb, Barbara D. Foleno, and Karen Bush Antimicrob. Agents Chemother. November 2001 45: 3182-3188; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Fungal Phospholipase Activity and Susceptibility to Lipid Preparations of Amphotericin B Magnus Gottfredsson, Chad J. Jessup, Gary M. Cox, John R. Perfect, and Mahmoud A. Ghannoum Antimicrob. Agents Chemother. November 2001 45: 3231-3233; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Congeners of SMAP29 Kill Ovine Pathogens and Induce Ultrastructural Damage in Bacterial Cells V. C. Kalfa, H. P. Jia, R. A. Kunkle, P. B. McCray, Jr., B. F. Tack, and K. A. Brogden Antimicrob. Agents Chemother. November 2001 45: 3256-3261; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Eradication of Biofilm-Forming Staphylococcus epidermidis (RP62A) by a Combination of Sodium Salicylate and Vancomycin Roy E. Polonio, Leonard A. Mermel, Gregory E. Paquette, and Jay F. Sperry Antimicrob. Agents Chemother. November 2001 45: 3262-3266; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Experimental Therapeutics:

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Efficacies of Moxifloxacin, Ciprofloxacin, and Vancomycin against Experimental Endocarditis Due to Methicillin-Resistant Staphylococcus aureus Expressing Various Degrees of Ciprofloxacin Resistance J. M. Entenza, Y. A. Que, J. Vouillamoz, M. P. Glauser, and P. Moreillon Antimicrob. Agents Chemother. November 2001 45: 3076-3083; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pharmacodynamics and Bactericidal Activity of Moxifloxacin in Experimental Escherichia coli Meningitis Violeta Rodriguez-Cerrato, Cynthia C. McCoig, Ian C. Michelow, Faryal Ghaffar, Hasan S. Jafri, Robert D. Hardy, Chetan Patel, Kurt Olsen, and George H. McCracken, Jr. Antimicrob. Agents Chemother. November 2001 45: 3092-3097; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

BMS-284756 in Experimental Cephalosporin-Resistant Pneumococcal Meningitis Violeta Rodriguez-Cerrato, Faryal Ghaffar, Jesus Saavedra, Ian C. Michelow, Robert D. Hardy, Janie Iglehart, Kurt Olsen, and George H. McCracken, Jr. Antimicrob. Agents Chemother. November 2001 45: 3098-3103; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Activities of New Macrolides and Fluoroquinolones against Mycobacterium ulcerans Infection in Mice Abdelhalim Bentoucha, Jérôme Robert, Hervé Dega, Nacer Lounis, Vincent Jarlier, and Jacques Grosset Antimicrob. Agents Chemother. November 2001 45: 3109-3112; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

New Model of Oropharyngeal Candidiasis in Mice Yasuki Kamai, Mikie Kubota, Yoko Kamai, Tsunemichi Hosokawa, Takashi Fukuoka, and Scott G. Filler Antimicrob. Agents Chemother. November 2001 45: 3195-3197; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Efficacies of Clarithromycin Regimens against Mycobacterium xenopi in Mice Nacer Lounis, Chantal Truffot-Pernot, Abdelhalim Bentoucha, Jerome Robert, Baohong Ji, and Jacques Grosset Antimicrob. Agents Chemother. November 2001 45: 3229-3230; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro and In Vivo Effects of Quinupristin-Dalfopristin against Pneumocystis carinii Peter D. Walzer, Alan Ashbaugh, Margaret Collins, and Melanie T. Cushion Antimicrob. Agents Chemother. November 2001 45: 3234-3237; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vivo Efficacy of Telithromycin (HMR3647) against Streptococcus pneumoniae and Haemophilus influenzae Hiroki Okamoto, Shuichi Miyazaki, Kazuhiro Tateda, Yoshikazu Ishii, and Keizo Yamaguchi Antimicrob. Agents Chemother. November 2001 45: 3250-3252; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Clinical Therapeutics:

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Treatment of Vancomycin-Resistant Enterococcal Infections in the Immunocompromised Host: Quinupristin-Dalfopristin in Combination with Minocycline Issam Raad, Ray Hachem, Hend Hanna, Essam Girgawy, Kenneth Rolston, Estella Whimbey, Rola Husni, and Gerald Bodey Antimicrob. Agents Chemother. November 2001 45: 3202-3204; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.