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Minireviews:

Michel Arthur and Richard Quintiliani, Jr.

Regulation of VanA- and VanB-Type Glycopeptide Resistance in Enterococci
Antimicrob. Agents Chemother. 2001 45: 375-381. [Full Text] [PDF] [Reprints and Permissions]  

Pharmacology:

Zeruesenay Desta, Nadia V. Soukhova, and David A. Flockhart

Inhibition of Cytochrome P450 (CYP450) Isoforms by Isoniazid: Potent Inhibition of CYP2C19 and CYP3A
Antimicrob. Agents Chemother. 2001 45: 382-392. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ronald E. Polk, Donald F. Brophy, Debra S. Israel, Roberto Patron, Brian M. Sadler, Gregory E. Chittick, William T. Symonds, Yu Lou, Debbie Kristoff, and D. S. Stein

Pharmacokinetic Interaction between Amprenavir and Rifabutin or Rifampin in Healthy Males
Antimicrob. Agents Chemother. 2001 45: 502-508. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sanjeev Krishna, Tim Planche, Tsiri Agbenyega, Charles Woodrow, Dan Agranoff, George Bedu-Addo, Alex K. Owusu-Ofori, John Adabie Appiah, Surash Ramanathan, Sharif M. Mansor, and Visweswaran Navaratnam

Bioavailability and Preliminary Clinical Efficacy of Intrarectal Artesunate in Ghanaian Children with Moderate Malaria
Antimicrob. Agents Chemother. 2001 45: 509-516. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jeffrey M. Jacobson, Lawrence Feinman, Leonard Liebes, Nancy Ostrow, Victoria Koslowski, Alfonso Tobia, Bernard E. Cabana, Dong-Hun Lee, John Spritzler, and Alfred M. Prince

Pharmacokinetics, Safety, and Antiviral Effects of Hypericin, a Derivative of St. John's Wort Plant, in Patients with Chronic Hepatitis C Virus Infection
Antimicrob. Agents Chemother. 2001 45: 517-524. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ann Allen, Elizabeth Bygate, Marika Vousden, Stuart Oliver, Martin Johnson, Christopher Ward, Ae-Jin Cheon, Youn Sung Choo, and In-Chull Kim

Multiple-Dose Pharmacokinetics and Tolerability of Gemifloxacin Administered Orally to Healthy Volunteers
Antimicrob. Agents Chemother. 2001 45: 540-545. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Andreas H. Groll, Bryan M. Gullick, Ruta Petraitiene, Vidmantas Petraitis, Myrna Candelario, Stephen C. Piscitelli, and Thomas J. Walsh

Compartmental Pharmacokinetics of the Antifungal Echinocandin Caspofungin (MK-0991) in Rabbits
Antimicrob. Agents Chemother. 2001 45: 596-600. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Karl V. Clemons, Raymond A. Sobel, Paul L. Williams, and David A. Stevens

Comparative Toxicities and Pharmacokinetics of Intrathecal Lipid (Amphotericin B Colloidal Dispersion) and Conventional Deoxycholate Formulations of Amphotericin B in Rabbits
Antimicrob. Agents Chemother. 2001 45: 612-615. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Antiviral Agents:

Robert W. Buckheit, Jr., Karen Watson, Valerie Fliakas-Boltz, Julie Russell, Tracy L. Loftus, Mark C. Osterling, Jim A. Turpin, Luke A. Pallansch, E. Lucile White, J.-W. Lee, S.-H. Lee, J.-W. Oh, H.-S. Kwon, S.-G. Chung, and E.-H. Cho

SJ-3366, a Unique and Highly Potent Nonnucleoside Reverse Transcriptase Inhibitor of Human Immunodeficiency Virus Type 1 (HIV-1) That Also Inhibits HIV-2
Antimicrob. Agents Chemother. 2001 45: 393-400. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Atsuko Hachiya, Saori Aizawa-Matsuoka, Mari Tanaka, Yukiko Takahashi, Setsuko Ida, Hiroyuki Gatanaga, Yoshihiro Hirabayashi, Asato Kojima, Masashi Tatsumi, and Shinichi Oka

Rapid and Simple Phenotypic Assay for Drug Susceptibility of Human Immunodeficiency Virus Type 1 Using CCR5-Expressing HeLa/CD4⁺ Cell Clone 1-10 (MAGIC-5)
Antimicrob. Agents Chemother. 2001 45: 495-501. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

P. G. Hoggard, S. D. Sales, D. Phiboonbanakit, J. Lloyd, B. A. Maher, S. H. Khoo, E. Wilkins, P. Carey, C. A. Hart, and D. J. Back

Influence of Prior Exposure to Zidovudine on Stavudine Phosphorylation In Vivo and Ex Vivo
Antimicrob. Agents Chemother. 2001 45: 577-582. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Dana G. Wolf, Isaac Yaniv, Shai Ashkenazi, and Alik Honigman

Emergence of Multiple Human Cytomegalovirus Ganciclovir-Resistant Mutants with Deletions and Substitutions within the UL97 Gene in a Patient with Severe Combined Immunodeficiency
Antimicrob. Agents Chemother. 2001 45: 593-595. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Biologic Response Modifiers:

Etsuro Sato, Dan K. Nelson, Sekiya Koyama, Jeffrey C. Hoyt, and Richard A. Robbins

Erythromycin Modulates Eosinophil Chemotactic Cytokine Production by Human Lung Fibroblasts in Vitro
Antimicrob. Agents Chemother. 2001 45: 401-406. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ross D. LeClaire and Sina Bavari

Human Antibodies to Bacterial Superantigens and Their Ability To Inhibit T-Cell Activation and Lethality
Antimicrob. Agents Chemother. 2001 45: 460-463. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Malika Larabi, Philippe Legrand, Martine Appel, Sophie Gil, Michel Lepoivre, Jean-Philippe Devissaguet, Francis Puisieux, and Gillian Barratt

Reduction of NO Synthase Expression and Tumor Necrosis Factor Alpha Production in Macrophages by Amphotericin B Lipid Carriers
Antimicrob. Agents Chemother. 2001 45: 553-562. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sudhir Sharma, Indu Verma, and G. K. Khuller

Therapeutic Potential of Human Neutrophil Peptide 1 against Experimental Tuberculosis
Antimicrob. Agents Chemother. 2001 45: 639-640. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Action:

Gesine Schrader-Fischer and Brigitte Berger-Bächi

The AbcA Transporter of Staphylococcus aureus Affects Cell Autolysis
Antimicrob. Agents Chemother. 2001 45: 407-412. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

José M. Pérez-Victoria, F. Javier Pérez-Victoria, Gwenaëlle Conseil, Mathias Maitrejean, Gilles Comte, Denis Barron, Attilio Di Pietro, Santiago Castanys, and Francisco Gamarro

High-Affinity Binding of Silybin Derivatives to the Nucleotide-Binding Domain of a Leishmania tropica P-Glycoprotein-Like Transporter and Chemosensitization of a Multidrug-Resistant Parasite to Daunomycin
Antimicrob. Agents Chemother. 2001 45: 439-446. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Brunello Oliva, Alexander O'Neill, Jenny M. Wilson, Peter J. O'Hanlon, and Ian Chopra

Antimicrobial Properties and Mode of Action of the Pyrrothine Holomycin
Antimicrob. Agents Chemother. 2001 45: 532-539. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Resistance:

Matthew B. Avison, Catherine S. Higgins, Charlotte J. von Heldreich, Peter M. Bennett, and Timothy R. Walsh

Plasmid Location and Molecular Heterogeneity of the L1 and L2 -Lactamase Genes of Stenotrophomonas maltophilia
Antimicrob. Agents Chemother. 2001 45: 413-419. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jianping Xu, Chiatogu Onyewu, Heather J. Yoell, Rabia Y. Ali, Rytas J. Vilgalys, and Thomas G. Mitchell

Dynamic and Heterogeneous Mutations to Fluconazole Resistance in Cryptococcus neoformans
Antimicrob. Agents Chemother. 2001 45: 420-427. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Rungtip Chuanchuen, Kerry Beinlich, Tung T. Hoang, Anna Becher, RoxAnn R. Karkhoff-Schweizer, and Herbert P. Schweizer

Cross-Resistance between Triclosan and Antibiotics in Pseudomonas aeruginosa Is Mediated by Multidrug Efflux Pumps: Exposure of a Susceptible Mutant Strain to Triclosan Selects nfxB Mutants Overexpressing MexCD-OprJ
Antimicrob. Agents Chemother. 2001 45: 428-432. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Joseph M. Blondeau, Xilin Zhao, Glen Hansen, and Karl Drlica

Mutant Prevention Concentrations of Fluoroquinolones for Clinical Isolates of Streptococcus pneumoniae
Antimicrob. Agents Chemother. 2001 45: 433-438. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Laurent Poirel, Delphine Girlich, Thierry Naas, and Patrice Nordmann

OXA-28, an Extended-Spectrum Variant of OXA-10 -Lactamase from Pseudomonas aeruginosa and Its Plasmid- and Integron-Located Gene
Antimicrob. Agents Chemother. 2001 45: 447-453. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hyunjoo Pai, Jong-Won Kim, Jungmin Kim, Ji Hyang Lee, Kang Won Choe, and Naomasa Gotoh

Carbapenem Resistance Mechanisms in Pseudomonas aeruginosa Clinical Isolates
Antimicrob. Agents Chemother. 2001 45: 480-484. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Laurent Poirel, Thierry Lambert, Salih Türkoglü, Esthel Ronco, Jean-Louis Gaillard, and Patrice Nordmann

Characterization of Class 1 Integrons from Pseudomonas aeruginosa That Contain the bla_VIM-2 Carbapenem-Hydrolyzing -Lactamase Gene and of Two Novel Aminoglycoside Resistance Gene Cassettes
Antimicrob. Agents Chemother. 2001 45: 546-552. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mariya Afzal-Shah, Neil Woodford, and David M. Livermore

Characterization of OXA-25, OXA-26, and OXA-27, Molecular Class D -Lactamases Associated with Carbapenem Resistance in Clinical Isolates of Acinetobacter baumannii
Antimicrob. Agents Chemother. 2001 45: 583-588. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Antonio Oliver, José Claudio Pérez-Díaz, Teresa M. Coque, Fernando Baquero, and Rafael Cantón

Nucleotide Sequence and Characterization of a Novel Cefotaxime-Hydrolyzing -Lactamase (CTX-M-10) Isolated in Spain
Antimicrob. Agents Chemother. 2001 45: 616-620. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Milagro Reig, Juan-Carlos Galan, Fernando Baquero, and Jose Claudio Perez-Diaz

Macrolide Resistance in Peptostreptococcus spp. Mediated by ermTR: Possible Source of Macrolide-Lincosamide-Streptogramin B Resistance in Streptococcus pyogenes
Antimicrob. Agents Chemother. 2001 45: 630-632. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Frederic Fitoussi, Catherine Doit, Pierre Geslin, Naima Brahimi, and Edouard Bingen

Mechanisms of Macrolide Resistance in Clinical Pneumococcal Isolates in France
Antimicrob. Agents Chemother. 2001 45: 636-638. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Experimental Therapeutics:

Ronda L. Akins and Michael J. Rybak

Bactericidal Activities of Two Daptomycin Regimens against Clinical Strains of Glycopeptide Intermediate-Resistant Staphylococcus aureus, Vancomycin-Resistant Enterococcus faecium, and Methicillin-Resistant Staphylococcus aureus Isolates in an In Vitro Pharmacodynamic Model with Simulated Endocardial Vegetations
Antimicrob. Agents Chemother. 2001 45: 454-459. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Raymond M. Schiffelers, Gert Storm, Marian T. ten Kate, and Irma A. J. M. Bakker-Woudenberg

Therapeutic Efficacy of Liposome-Encapsulated Gentamicin in Rat Klebsiella pneumoniae Pneumonia in Relation to Impaired Host Defense and Low Bacterial Susceptibility to Gentamicin
Antimicrob. Agents Chemother. 2001 45: 464-470. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Vidmantas Petraitis, Ruta Petraitiene, Andreas H. Groll, Tin Sein, Robert L. Schaufele, Caron A. Lyman, Andrea Francesconi, John Bacher, Stephen C. Piscitelli, and Thomas J. Walsh

Dosage-Dependent Antifungal Efficacy of V-Echinocandin (LY303366) against Experimental Fluconazole-Resistant Oropharyngeal and Esophageal Candidiasis
Antimicrob. Agents Chemother. 2001 45: 471-479. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Arnold Louie, Pamela Kaw, Partha Banerjee, Weiguo Liu, George Chen, and Michael H. Miller

Impact of the Order of Initiation of Fluconazole and Amphotericin B in Sequential or Combination Therapy on Killing of Candida albicans In Vitro and in a Rabbit Model of Endocarditis and Pyelonephritis
Antimicrob. Agents Chemother. 2001 45: 485-494. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

John M. Clements, R. Paul Beckett, Anthony Brown, Graham Catlin, Mario Lobell, Shilpa Palan, Wayne Thomas, Mark Whittaker, Stephen Wood, Sameeh Salama, Patrick J. Baker, H. Fiona Rodgers, Vladimir Barynin, David W. Rice, and Michael G. Hunter

Antibiotic Activity and Characterization of BB-3497, a Novel Peptide Deformylase Inhibitor
Antimicrob. Agents Chemother. 2001 45: 563-570. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

O. F. Join-Lambert, M. Michéa-Hamzehpour, T. Köhler, F. Chau, F. Faurisson, S. Dautrey, C. Vissuzaine, C. Carbon, and J.-C. Pechère

Differential Selection of Multidrug Efflux Mutants by Trovafloxacin and Ciprofloxacin in an Experimental Model of Pseudomonas aeruginosa Acute Pneumonia in Rats
Antimicrob. Agents Chemother. 2001 45: 571-576. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Alan M. Sugar and Xiu-Ping Liu

Efficacy of Voriconazole in Treatment of Murine Pulmonary Blastomycosis
Antimicrob. Agents Chemother. 2001 45: 601-604. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Robin Patel, Mark S. Rouse, Kerryl E. Piper, and James M. Steckelberg

Linezolid Therapy of Vancomycin-Resistant Enterococcus faecium Experimental Endocarditis
Antimicrob. Agents Chemother. 2001 45: 621-623. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Clinical Therapeutics:

G. Siami, N. Christou, I. Eiseman, K. J. Tack, and the Clinafloxacin Severe Skin And Soft Tissue Infections Study Group

Clinafloxacin versus Piperacillin-Tazobactam in Treatment of Patients with Severe Skin and Soft Tissue Infections
Antimicrob. Agents Chemother. 2001 45: 525-531. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Gloria Garcia-Calvo, Ana Molleja, Maria J. Giménez, Araceli Parra, Eva Nieto, Carmen Ponte, Lorenzo Aguilar, and Francisco Soriano

Effects of Single Oral Doses of Gemifloxacin (320 Milligrams) versus Trovafloxacin (200 Milligrams) on Fecal Flora in Healthy Volunteers
Antimicrob. Agents Chemother. 2001 45: 608-611. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Susceptibility:

Dianne B. Hoellman, Linda M. Kelly, Michael R. Jacobs, and Peter C. Appelbaum

Comparative Antianaerobic Activity of BMS 284756
Antimicrob. Agents Chemother. 2001 45: 589-592. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

A. Espinel-Ingroff

Germinated and Nongerminated Conidial Suspensions for Testing of Susceptibilities of Aspergillus spp. to Amphotericin B, Itraconazole, Posaconazole, Ravuconazole, and Voriconazole
Antimicrob. Agents Chemother. 2001 45: 605-607. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Fernando Alcaide, Miguel Angel Benítez, Jordi Carratalà, Francesc Gudiol, Josefina Liñares, and Rogelio Martín

In Vitro Activities of the New Ketolide HMR 3647 (Telithromycin) in Comparison with Those of Eight Other Antibiotics against Viridans Group Streptococci Isolated from Blood of Neutropenic Patients with Cancer
Antimicrob. Agents Chemother. 2001 45: 624-626. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mohamed Benbachir, Saida Benredjeb, Cheick Saadbouh Boye, Mireille Dosso, Houria Belabbes, Aouatef Kamoun, Omar Kaire, and Naima Elmdaghri

Two-Year Surveillance of Antibiotic Resistance in Streptococcus pneumoniae in Four African Cities
Antimicrob. Agents Chemother. 2001 45: 627-629. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Gloria M. González, Deanna A. Sutton, Elizabeth Thompson, Rolando Tijerina, and Michael G. Rinaldi

In Vitro Activities of Approved and Investigational Antifungal Agents against 44 Clinical Isolates of Basidiomycetous Fungi
Antimicrob. Agents Chemother. 2001 45: 633-635. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Letters:

Shigeru Fujimura, Akira Watanabe, and David Beighton

Characterization of the mupA Gene in Strains of Methicillin-Resistant Staphylococcus aureus with a Low Level of Resistance to Mupirocin
Antimicrob. Agents Chemother. 2001 45: 641-642. [Full Text] [PDF] [Reprints and Permissions]  

Josep M. Sierra, Joaquin Ruiz, Margarita M. Navia, Martha Vargas, Joaquim Gascon, and Jordi Vila

In Vitro Activity of Rifaximin against Enteropathogens Producing Traveler's Diarrhea
Antimicrob. Agents Chemother. 2001 45: 643-644. [Full Text] [PDF] [Reprints and Permissions]  

Mehnam Soltani, David Beighton, John Philpott-Howard, and Neil Woodford

Identification of vat(E-3), a Novel Gene Encoding Resistance to Quinupristin-Dalfopristin in a Strain of Enterococcus faecium from a Hospital Patient in the United Kingdom
Antimicrob. Agents Chemother. 2001 45: 645-646. [Full Text] [PDF] [Reprints and Permissions]  

Errata:

Diana L. Williams, Laynette Spring, Eugene Harris, Paul Roche, and Thomas P. Gillis

Dihydropteroate Synthase of Mycobacterium leprae and Dapsone Resistance
Antimicrob. Agents Chemother. 2001 45: 647. [Full Text] [PDF] [Reprints and Permissions]  

Annarita Mazzariol, Yutaka Tokue, Tiffany M. Kanegawa, Giuseppe Cornaglia, and Hiroshi Nikaido

High-Level Fluoroquinolone-Resistant Clinical Isolates of Escherichia coli Overproduce Multidrug Efflux Protein AcrA
Antimicrob. Agents Chemother. 2001 45: 647. [Full Text] [PDF] [Reprints and Permissions]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.