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Mechanisms of Action:

Gisbert Schumann and Ute Möllmann

Screening System for Xenosiderophores as Potential Drug Delivery Agents in Mycobacteria
Antimicrob. Agents Chemother. 2001 45: 1317-1322. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Aleksander Patrzykat, Lijuan Zhang, Valentina Mendoza, George K. Iwama, and Robert E. W. Hancock

Synergy of Histone-Derived Peptides of Coho Salmon with Lysozyme and Flounder Pleurocidin
Antimicrob. Agents Chemother. 2001 45: 1337-1342. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jan Carlo Delorenzi, Márcia Attias, Cerli R. Gattass, Marcelo Andrade, Cláudia Rezende, Ângelo da Cunha Pinto, Amélia T. Henriques, Dumith C. Bou-Habib, and Elvira M. B. Saraiva

Antileishmanial Activity of an Indole Alkaloid from Peschiera australis
Antimicrob. Agents Chemother. 2001 45: 1349-1354. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Yufang Ma, Richard J. Stern, Michael S. Scherman, Varalakshmi D. Vissa, Wenxin Yan, Victoria Cox Jones, Fangqiu Zhang, Scott G. Franzblau, Walter H. Lewis, and Michael R. McNeil

Drug Targeting Mycobacterium tuberculosis Cell Wall Synthesis: Genetics of dTDP-Rhamnose Synthetic Enzymes and Development of a Microtiter Plate-Based Screen for Inhibitors of Conversion of dTDP-Glucose to dTDP-Rhamnose
Antimicrob. Agents Chemother. 2001 45: 1407-1416. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

M. D. Ball, M. S. Bartlett, M. Shaw, J. W. Smith, M. Nasr, and S. R. Meshnick

Activities and Conformational Fitting of 1,4-Naphthoquinone Derivatives and Other Cyclic 1,4-Diones Tested In Vitro against Pneumocystis carinii
Antimicrob. Agents Chemother. 2001 45: 1473-1479. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kumiko Nagata, Nobuhito Sone, and Toshihide Tamura

Inhibitory Activities of Lansoprazole against Respiration in Helicobacter pylori
Antimicrob. Agents Chemother. 2001 45: 1522-1527. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Carlos A. Stella and Hilda I. Burgos

Effect of Potassium on Saccharomyces cerevisiae Resistance to Fluconazole
Antimicrob. Agents Chemother. 2001 45: 1589-1590. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Resistance:

Teruyo Ito, Yuki Katayama, Kazumi Asada, Namiko Mori, Kanae Tsutsumimoto, Chuntima Tiensasitorn, and Keiichi Hiramatsu

Structural Comparison of Three Types of Staphylococcal Cassette Chromosome mec Integrated in the Chromosome in Methicillin-Resistant Staphylococcus aureus
Antimicrob. Agents Chemother. 2001 45: 1323-1336. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hisakazu Yano, Akio Kuga, Ryoichi Okamoto, Hidero Kitasato, Toshimitsu Kobayashi, and Matsuhisa Inoue

Plasmid-Encoded Metallo--Lactamase (IMP-6) Conferring Resistance to Carbapenems, Especially Meropenem
Antimicrob. Agents Chemother. 2001 45: 1343-1348. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Patrick Butaye, Luc A. Devriese, and Freddy Haesebrouck

Differences in Antibiotic Resistance Patterns of Enterococcus faecalis and Enterococcus faecium Strains Isolated from Farm and Pet Animals
Antimicrob. Agents Chemother. 2001 45: 1374-1378. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

A. S. Jellen-Ritter and W. V. Kern

Enhanced Expression of the Multidrug Efflux Pumps AcrAB and AcrEF Associated with Insertion Element Transposition in Escherichia coli Mutants Selected with a Fluoroquinolone
Antimicrob. Agents Chemother. 2001 45: 1467-1472. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Louis B. Rice, Lenore L. Carias, Rebecca Hutton-Thomas, Farid Sifaoui, Laurent Gutmann, and Susan D. Rudin

Penicillin-Binding Protein 5 and Expression of Ampicillin Resistance in Enterococcus faecium
Antimicrob. Agents Chemother. 2001 45: 1480-1486. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Leen-Jan van Doorn, Youri Glupczynski, Johannes G. Kusters, Francis Mégraud, Peter Midolo, Nadia Maggi-Solcà, Dulciene M. M. Queiroz, Nathalie Nouhan, Els Stet, and Wim G. V. Quint

Accurate Prediction of Macrolide Resistance in Helicobacter pylori by a PCR Line Probe Assay for Detection of Mutations in the 23S rRNA Gene: Multicenter Validation Study
Antimicrob. Agents Chemother. 2001 45: 1500-1504. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hui Wang, Joann L. Dzink-Fox, Minjun Chen, and Stuart B. Levy

Genetic Characterization of Highly Fluoroquinolone-Resistant Clinical Escherichia coli Strains from China: Role of acrR Mutations
Antimicrob. Agents Chemother. 2001 45: 1515-1521. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Patrícia A. Nunes, Sandra Tenreiro, and Isabel Sá-Correia

Resistance and Adaptation to Quinidine in Saccharomyces cerevisiae: Role of QDR1 (YIL120w), Encoding a Plasma Membrane Transporter of the Major Facilitator Superfamily Required for Multidrug Resistance
Antimicrob. Agents Chemother. 2001 45: 1528-1534. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mark A. Webber and Laura J. V. Piddock

Absence of Mutations in marRAB or soxRS in acrB-Overexpressing Fluoroquinolone-Resistant Clinical and Veterinary Isolates of Escherichia coli
Antimicrob. Agents Chemother. 2001 45: 1550-1552. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hans-Jörg Linde, Mario Schmidt, Emmi Fuchs, Udo Reischl, Hans-Helmut Niller, and Norbert Lehn

In Vitro Activities of Six Quinolones and Mechanisms of Resistance in Staphylococcus aureus and Coagulase-Negative Staphylococci
Antimicrob. Agents Chemother. 2001 45: 1553-1557. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Margaret Ip, Donald J. Lyon, Raymond W. H. Yung, Colin Chan, and Augustine F. B. Cheng

Macrolide Resistance in Streptococcus pneumoniae in Hong Kong
Antimicrob. Agents Chemother. 2001 45: 1578-1580. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Lesley McGee, Keith P. Klugman, Avril Wasas, Thora Capper, Adrian Brink, and The Antibiotics Surveillance Forum Of South Africa

Serotype 19F Multiresistant Pneumococcal Clone Harboring Two Erythromycin Resistance Determinants [erm(B) and mef(A)] in South Africa
Antimicrob. Agents Chemother. 2001 45: 1595-1598. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Susceptibility:

Francesco Barchiesi, Anna Maria Schimizzi, Laura K. Najvar, Rosie Bocanegra, Francesca Caselli, Simona Di Cesare, Daniele Giannini, Luigi Falconi Di Francesco, Andrea Giacometti, Flavia Carle, Giorgio Scalise, and John R. Graybill

Interactions of Posaconazole and Flucytosine against Cryptococcus neoformans
Antimicrob. Agents Chemother. 2001 45: 1355-1359. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

John M. Kelly, Guenter Quack, and Michael M. Miles

In Vitro and In Vivo Activities of Aminoadamantane and Aminoalkylcyclohexane Derivatives against Trypanosoma brucei
Antimicrob. Agents Chemother. 2001 45: 1360-1366. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Daniel F. Sahm, Clyde Thornsberry, David C. Mayfield, Mark E. Jones, and James A. Karlowsky

Multidrug-Resistant Urinary Tract Isolates of Escherichia coli: Prevalence and Patient Demographics in the United States in 2000
Antimicrob. Agents Chemother. 2001 45: 1402-1406. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Philip Domenico, Lucilla Baldassarri, Paul E. Schoch, Kristina Kaehler, Masanori Sasatsu, and Burke A. Cunha

Activities of Bismuth Thiols against Staphylococci and Staphylococcal Biofilms
Antimicrob. Agents Chemother. 2001 45: 1417-1421. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Suzanne Chamberland, Johanne Blais, Monica Hoang, Cynthia Dinh, Dylan Cotter, Emmett Bond, Carla Gannon, Craig Park, Francois Malouin, and Michael N. Dudley

In Vitro Activities of RWJ-54428 (MC-02,479) against Multiresistant Gram-Positive Bacteria
Antimicrob. Agents Chemother. 2001 45: 1422-1430. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Donatella Taramelli, Clara Tognazioli, F. Ravagnani, O. Leopardi, G. Giannulis, and J. R. Boelaert

Inhibition of Intramacrophage Growth of Penicillium marneffei by 4-Aminoquinolines
Antimicrob. Agents Chemother. 2001 45: 1450-1455. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

J. Mosquera, P. A. Warn, J. Morrissey, C. B. Moore, C. Gil-Lamaignere, and D. W. Denning

Susceptibility Testing of Aspergillus flavus: Inoculum Dependence with Itraconazole and Lack of Correlation between Susceptibility to Amphotericin B In Vitro and Outcome In Vivo
Antimicrob. Agents Chemother. 2001 45: 1456-1462. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ana Gales, Helio Sader, and Ronald N. Jones

Activities of BMS 284756 (T-3811) against Haemophilus influenzae, Moraxella catarrhalis, and Streptococcus pneumoniae Isolates from SENTRY Antimicrobial Surveillance Program Medical Centers in Latin America (1999)
Antimicrob. Agents Chemother. 2001 45: 1463-1466. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Karin Seifert, Michael Duchêne, Walther H. Wernsdorfer, Herwig Kollaritsch, Otto Scheiner, Gerhard Wiedermann, Thomas Hottkowitz, and Hansjörg Eibl

Effects of Miltefosine and Other Alkylphosphocholines on Human Intestinal Parasite Entamoeba histolytica
Antimicrob. Agents Chemother. 2001 45: 1505-1510. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Michael Tracy, Anna Wanahita, Yevgeny Shuhatovich, Elizabeth A. Goldsmith, Jill E. Clarridge, III, and Daniel M. Musher

Antibiotic Susceptibilities of Genetically Characterized Streptococcus milleri Group Strains
Antimicrob. Agents Chemother. 2001 45: 1511-1514. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hong Yan and Robert E. W. Hancock

Synergistic Interactions between Mammalian Antimicrobial Defense Peptides
Antimicrob. Agents Chemother. 2001 45: 1558-1560. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Raffaele Piccolomini, Giovanni Di Bonaventura, Carla Picciani, Francesco Laterza, Jacopo Vecchiet, and Matteo Neri

In Vitro Activity of Clarithromycin against Intracellular Helicobacter pylori
Antimicrob. Agents Chemother. 2001 45: 1568-1571. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sylvia Valdezate, Ana Vindel, Elena Loza, Fernando Baquero, and Rafael Cantón

Antimicrobial Susceptibilities of Unique Stenotrophomonas maltophilia Clinical Strains
Antimicrob. Agents Chemother. 2001 45: 1581-1584. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Arthur L. Barry, Peter C. Fuchs, and Steven D. Brown

Identification of -Lactamase-Negative, Ampicillin-Resistant Strains of Haemophilus influenzae with Four Methods and Eight Media
Antimicrob. Agents Chemother. 2001 45: 1585-1588. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Chemistry; Biosynthesis:

David M. Rothstein, Peter Spacciapoli, Linh T. Tran, Tao Xu, F. Donald Roberts, Mauro Dalla Serra, Deborah K. Buxton, Frank G. Oppenheim, and Phillip Friden

Anticandida Activity Is Retained in P-113, a 12-Amino-Acid Fragment of Histatin 5
Antimicrob. Agents Chemother. 2001 45: 1367-1373. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pharmacology:

Terri Creagh, Jon L. Ruckle, Dwain T. Tolbert, Jeremy Giltner, David A. Eiznhamer, Bipul Dutta, Michael T. Flavin, and Ze-Qi Xu

Safety and Pharmacokinetics of Single Doses of (+)-Calanolide A, a Novel, Naturally Occurring Nonnucleoside Reverse Transcriptase Inhibitor, in Healthy, Human Immunodeficiency Virus-Negative Human Subjects
Antimicrob. Agents Chemother. 2001 45: 1379-1386. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Claudine Schmitt, Yves Perel, Jean-luc Harousseau, Sophie Lemerle, Elisabeth Chwetzoff, Jean-Pierre le Moing, and Jean-Claude Levron

Pharmacokinetics of Itraconazole Oral Solution in Neutropenic Children during Long-Term Prophylaxis
Antimicrob. Agents Chemother. 2001 45: 1561-1564. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Yishai Haimi-Cohen, Neghma Husain, Jerry Meenan, Gungor Karayalcin, Michael Lehrer, and Lorry G. Rubin

Vancomycin and Ceftazidime Bioactivities Persist for at Least 2 Weeks in the Lumen in Ports: Simplifying Treatment of Port-Associated Bloodstream Infections by Using the Antibiotic Lock Technique
Antimicrob. Agents Chemother. 2001 45: 1565-1567. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Richard Hafner, James Bethel, Harold C. Standiford, Stephen Follansbee, David L. Cohn, Ronald E. Polk, Larry Mole, Ralph Raasch, Princy Kumar, David Mushatt, and George Drusano

Tolerance and Pharmacokinetic Interactions of Rifabutin and Azithromycin
Antimicrob. Agents Chemother. 2001 45: 1572-1577. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Experimental Therapeutics:

Pedro López, Joan Gavaldà, M. Teresa Martin, Benito Almirante, Xavier Gomis, Carlos Azuaje, Nuria Borrell, Leonor Pou, Vicenç Falcó, Carles Pigrau, and Albert Pahissa

Efficacy of Teicoplanin-Gentamicin Given Once a Day on the Basis of Pharmacokinetics in Humans for Treatment of Enterococcal Experimental Endocarditis
Antimicrob. Agents Chemother. 2001 45: 1387-1393. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Lorna E. T. Stearne, Inge C. Gyssens, Wil H. F. Goessens, Johan W. Mouton, Wim J. G. Oyen, Jos W. M. van der Meer, and Henri A. Verbrugh

In Vivo Efficacy of Trovafloxacin against Bacteroides fragilis in Mixed Infection with either Escherichia coli or a Vancomycin-Resistant Strain of Enterococcus faecium in an Established-Abscess Murine Model
Antimicrob. Agents Chemother. 2001 45: 1394-1401. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Michael W. Climo, Kerstin Ehlert, and Gordon L. Archer

Mechanism and Suppression of Lysostaphin Resistance in Oxacillin-Resistant Staphylococcus aureus
Antimicrob. Agents Chemother. 2001 45: 1431-1437. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Irma A. J. M. Bakker-Woudenberg, Marian T. ten Kate, Luke Guo, Peter Working, and Johan W. Mouton

Improved Efficacy of Ciprofloxacin Administered in Polyethylene Glycol-Coated Liposomes for Treatment of Klebsiella pneumoniae Pneumonia in Rats
Antimicrob. Agents Chemother. 2001 45: 1487-1492. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Yoshiyuki Tatsumi, Mamoru Yokoo, Tadashi Arika, and Hideyo Yamaguchi

In Vitro Antifungal Activity of KP-103, a Novel Triazole Derivative, and Its Therapeutic Efficacy against Experimental Plantar Tinea Pedis and Cutaneous Candidiasis in Guinea Pigs
Antimicrob. Agents Chemother. 2001 45: 1493-1499. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Stefano Bassetti, Jean Hu, Ralph B. D'Agostino, Jr., and Robert J. Sherertz

Prolonged Antimicrobial Activity of a Catheter Containing Chlorhexidine-Silver Sulfadiazine Extends Protection against Catheter Infections In Vivo
Antimicrob. Agents Chemother. 2001 45: 1535-1538. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Antiviral Agents:

John Mittler, Paulina Essunger, Geoffrey J. Yuen, Neil Clendeninn, Martin Markowitz, and Alan S. Perelson

Short-Term Measures of Relative Efficacy Predict Longer-Term Reductions in Human Immunodeficiency Virus Type 1 RNA Levels following Nelfinavir Monotherapy
Antimicrob. Agents Chemother. 2001 45: 1438-1443. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jason C. Lenzo, Geoffrey R. Shellam, and Cassandra M. Lawson

Ganciclovir and Cidofovir Treatment of Cytomegalovirus-Induced Myocarditis in Mice
Antimicrob. Agents Chemother. 2001 45: 1444-1449. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ei-Ichi Kodama, Satoru Kohgo, Kenji Kitano, Haruhiko Machida, Hiroyuki Gatanaga, Shiro Shigeta, Masao Matsuoka, Hiroshi Ohrui, and Hiroaki Mitsuya

4'-Ethynyl Nucleoside Analogs: Potent Inhibitors of Multidrug-Resistant Human Immunodeficiency Virus Variants In Vitro
Antimicrob. Agents Chemother. 2001 45: 1539-1546. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Biologic Response Modifiers:

Nicole P. Juffermans, Annelies Verbon, Marc J. Schultz, C. Erik Hack, Sander J. H. van Deventer, Peter Speelman, and Tom van der Poll

Thalidomide Inhibits Granulocyte Responses in Healthy Humans after Ex Vivo Stimulation with Bacterial Antigens
Antimicrob. Agents Chemother. 2001 45: 1547-1549. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ferdinando Nicoletti, Roberto Di Marco, Paola Sacerdote, PierLuigi Meroni, Katia Mangano, Carl Edwards, III, Alberto Bartorelli, Klaus Bendtzen, and Alberto Panerai

Prevention and Treatment of Lethal Murine Endotoxemia by the Novel Immunomodulatory Agent MFP-14
Antimicrob. Agents Chemother. 2001 45: 1591-1594. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Letters:

Alexander John O'Neill, Ian Chopra, José L. Martínez, and Fernando Baquero

Use of Mutator Strains for Characterization of Novel Antimicrobial Agents
Antimicrob. Agents Chemother. 2001 45: 1599-1600. [Full Text] [PDF] [Reprints and Permissions]  

L. K. Siu, J. Kamile Rasheed, Luis Martínez-Martínez, and George A. Jacoby

Is OmpK35 Specific for Ceftazadime Penetration?
Antimicrob. Agents Chemother. 2001 45: 1601-1602. [Full Text] [PDF] [Reprints and Permissions]  

Franz-Josef Schmitz, Jasmina Petridou, Nadine Astfalk, Sibylle Scheuring, Karl Köhrer, Jan Verhoef, Ad C. Fluit, and Stefan Schwarz

Structural Alterations in the Translational Attenuator of Constitutively Expressed erm(A) Genes in Staphylococcus aureus
Antimicrob. Agents Chemother. 2001 45: 1603-1604. [Full Text] [PDF] [Reprints and Permissions]  

Pallavi Garg, Sutapa Sinha, Rupa Chakraborty, S. K. Bhattacharya, G. Balakrish Nair, T. Ramamurthy, and Yoshifumi Takeda

Emergence of Fluoroquinolone-Resistant Strains of Vibrio cholerae O1 Biotype El Tor among Hospitalized Patients with Cholera in Calcutta, India
Antimicrob. Agents Chemother. 2001 45: 1605-1606. [Full Text] [PDF] [Reprints and Permissions]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.