Contents: July 2001, Volume 45, Issue 7        Guest Commentary        Pharmacology        Susceptibility        Mechanisms of Resistance        Clinical Therapeutics        Experimental Therapeutics        Mechanisms of Action        Antiviral Agents        Letters Other Issues

Table of Contents

[Index by Author]

To see an article, click its [Full Text], [Abstract] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

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Guest Commentary:

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Search for New Drugs for Treatment of Tuberculosis Tuberculosis Drug Screening Program Antimicrob. Agents Chemother. July 2001 45: 1943-1946; [Full Text] [PDF] [Reprints and Permissions]

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Pharmacology:

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Effects of Renal Function on Pharmacokinetics of Recombinant Human Granulocyte Colony-Stimulating Factor in Lung Cancer Patients Masaaki Fukuda, Mikio Oka, Yoshimasa Ishida, Haruki Kinoshita, Kenji Terashi, Minoru Fukuda, Shigeru Kawabata, Akitoshi Kinoshita, Hiroshi Soda, and Shigeru Kohno Antimicrob. Agents Chemother. July 2001 45: 1947-1951; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Influence of Human Serum on Antifungal Pharmacodynamics with Candida albicans George G. Zhanel, David G. Saunders, Daryl J. Hoban, and James A. Karlowsky Antimicrob. Agents Chemother. July 2001 45: 2018-2022; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Heat Treatment of Amphotericin B Modifies Its Serum Pharmacokinetics, Tissue Distribution, and Renal Toxicity following Administration of a Single Intravenous Dose to Rabbits Evan H. Kwong, Manisha Ramaswamy, Emily A. Bauer, Scott C. Hartsel, and Kishor M. Wasan Antimicrob. Agents Chemother. July 2001 45: 2060-2063; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Safety and Pharmacokinetics of Multiple 750-Milligram Doses of Intravenous Levofloxacin in Healthy Volunteers Andrew T. Chow, Cynthia Fowler, R. Rex Williams, Nancy Morgan, Susan Kaminski, and Jaya Natarajan Antimicrob. Agents Chemother. July 2001 45: 2122-2125; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Fluoroquinolone Resistance in Anaerobic Bacteria following Exposure to Levofloxacin, Trovafloxacin, and Sparfloxacin in an In Vitro Pharmacodynamic Model Gigi H. Ross, David H. Wright, Laurie Baeker Hovde, Marnie L. Peterson, and John C. Rotschafer Antimicrob. Agents Chemother. July 2001 45: 2136-2140; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pharmacokinetic Evaluation of Oral Levofloxacin in Human Immunodeficiency Virus-Infected Subjects Receiving Concomitant Antiretroviral Therapy P. Villani, P. Viale, L. Signorini, B. Cadeo, F. Marchetti, A. Villani, C. Fiocchi, M. B. Regazzi, and G. Carosi Antimicrob. Agents Chemother. July 2001 45: 2160-2162; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Domestic Cat Model for Predicting Human Nucleoside Analogue Pharmacokinetics in Blood and Seminal Plasma Holly L. Jordan, Arlene S. Pereira, Myron S. Cohen, and Angela D. M. Kashuba Antimicrob. Agents Chemother. July 2001 45: 2173-2176; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Susceptibility:

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In Vitro Activities of Linezolid, Meropenem, and Quinupristin-Dalfopristin against Group C and G Streptococci, Including Vancomycin-Tolerant Isolates Theoklis Zaoutis, Lynn Steele Moore, Kathleen Furness, and Joel D. Klein Antimicrob. Agents Chemother. July 2001 45: 1952-1954; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Comparison of Hydrogen Peroxide Contact Lens Disinfection Systems and Solutions against Acanthamoeba polyphaga Reanne Hughes and Simon Kilvington Antimicrob. Agents Chemother. July 2001 45: 2038-2043; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Detection of Resistance to Amphotericin B in Candida Isolates by Using Iso-Sensitest Broth Manuel Cuenca-Estrella, Teresa M. Díaz-Guerra, Emilia Mellado, and Juan L. Rodríguez-Tudela Antimicrob. Agents Chemother. July 2001 45: 2070-2074; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Desbutyl-Benflumetol, a Novel Antimalarial Compound: In Vitro Activity in Fresh Isolates of Plasmodium falciparum from Thailand Harald Noedl, Thomas Allmendinger, Somsak Prajakwong, Gunther Wernsdorfer, and Walther H. Wernsdorfer Antimicrob. Agents Chemother. July 2001 45: 2106-2109; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Antibiotic Susceptibilities of Burkholderia mallei (Causative Agent of Glanders) Determined by Broth Microdilution and E-Test Henry S. Heine, Marilyn J. England, David M. Waag, and W. Russell Byrne Antimicrob. Agents Chemother. July 2001 45: 2119-2121; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antimicrobial Activities of Gatifloxacin against Nosocomial Isolates of Stenotrophomonas maltophilia Measured by MIC and Time-Kill Studies Michael L. Cohn and Ken B. Waites Antimicrob. Agents Chemother. July 2001 45: 2126-2128; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Macrolide-Resistant Streptococcus pneumoniae in Canada during 1998-1999: Prevalence of mef(A) and erm(B) and Susceptibilities to Ketolides Daryl J. Hoban, Aleksandra K. Wierzbowski, Kim Nichol, and George G. Zhanel Antimicrob. Agents Chemother. July 2001 45: 2147-2150; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activities of Four Novel Triazoles against Scedosporium spp. A. J. Carrillo and J. Guarro Antimicrob. Agents Chemother. July 2001 45: 2151-2153; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Comparative In Vitro Activity of ABT-773, a Novel Antibacterial Ketolide A. M. Nilius, M. H. Bui, L. Almer, D. Hensey-Rudloff, J. Beyer, Z. Ma, Y. S. Or, and R. K. Flamm Antimicrob. Agents Chemother. July 2001 45: 2163-2168; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Mechanisms of Resistance:

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Genetic Organization of the Chromosome Region Surrounding mecA in Clinical Staphylococcal Strains: Role of IS431-Mediated mecI Deletion in Expression of Resistance in mecA-Carrying, Low-Level Methicillin- Resistant Staphylococcus haemolyticus Yuki Katayama, Teruyo Ito, and Keiichi Hiramatsu Antimicrob. Agents Chemother. July 2001 45: 1955-1963; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pseudomonas aeruginosa Reveals High Intrinsic Resistance to Penem Antibiotics: Penem Resistance Mechanisms and Their Interplay Kiyomi Okamoto, Naomasa Gotoh, and Takeshi Nishino Antimicrob. Agents Chemother. July 2001 45: 1964-1971; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

gyrA Mutations Associated with Quinolone Resistance in Bacteroides fragilis Group Strains Herin Oh, Nagwa El Amin, Todd Davies, Peter C. Appelbaum, and Charlotta Edlund Antimicrob. Agents Chemother. July 2001 45: 1977-1981; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Inducible Macrolide Resistance in Corynebacterium jeikeium Adriana E. Rosato, Bonnie S. Lee, and Kevin A. Nash Antimicrob. Agents Chemother. July 2001 45: 1982-1989; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Interaction between DNA Gyrase and Quinolones: Effects of Alanine Mutations at GyrA Subunit Residues Ser83 and Asp87 Faye M. Barnard and Anthony Maxwell Antimicrob. Agents Chemother. July 2001 45: 1994-2000; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

MexXY-OprM Efflux Pump Is Required for Antagonism of Aminoglycosides by Divalent Cations in Pseudomonas aeruginosa Weimin Mao, Mark S. Warren, Angela Lee, Anita Mistry, and Olga Lomovskaya Antimicrob. Agents Chemother. July 2001 45: 2001-2007; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Identification of Proteus mirabilis Mutants with Increased Sensitivity to Antimicrobial Peptides Andrea J. McCoy, Hongjian Liu, Timothy J. Falla, and John S. Gunn Antimicrob. Agents Chemother. July 2001 45: 2030-2037; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Effect of Abolishment of the Use of Antimicrobial Agents for Growth Promotion on Occurrence of Antimicrobial Resistance in Fecal Enterococci from Food Animals in Denmark Frank Møller Aarestrup, Anne Mette Seyfarth, Hanne-Dorthe Emborg, Karl Pedersen, René S. Hendriksen, and Flemming Bager Antimicrob. Agents Chemother. July 2001 45: 2054-2059; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

All Detectable High-Molecular-Mass Penicillin-Binding Proteins Are Modified in a High-Level -Lactam-Resistant Clinical Isolate of Streptococcus mitis Ana Amoroso, Diego Demares, Marta Mollerach, Gabriel Gutkind, and Jacques Coyette Antimicrob. Agents Chemother. July 2001 45: 2075-2081; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

DNA Gyrase-Mediated Natural Resistance to Fluoroquinolones in Ehrlichia spp. M. Maurin, C. Abergel, and D. Raoult Antimicrob. Agents Chemother. July 2001 45: 2098-2105; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Discrimination of SHV -Lactamase Genes by Restriction Site Insertion-PCR Aroonwadee Chanawong, Fatima Hannachi M'Zali, John Heritage, Aroonlug Lulitanond, and Peter Michael Hawkey Antimicrob. Agents Chemother. July 2001 45: 2110-2114; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Molecular Characterization of a Novel Plasmid-Encoded Cefotaximase (CTX-M-12) Found in Clinical Klebsiella pneumoniae Isolates from Kenya S. Kariuki, J. E. Corkill, G. Revathi, R. Musoke, and C. A. Hart Antimicrob. Agents Chemother. July 2001 45: 2141-2143; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Resistance to Linezolid: Characterization of Mutations in rRNA and Comparison of Their Occurrences in Vancomycin-Resistant Enterococci Jason Prystowsky, Farida Siddiqui, John Chosay, Dean L. Shinabarger, John Millichap, Lance R. Peterson, and Gary A. Noskin Antimicrob. Agents Chemother. July 2001 45: 2154-2156; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Novel Mutations in ndh in Isoniazid-Resistant Mycobacterium tuberculosis Isolates Ann S. G. Lee, Audrey S. M. Teo, and Sin-Yew Wong Antimicrob. Agents Chemother. July 2001 45: 2157-2159; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Clinical Therapeutics:

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Safety and Bactericidal Activity of Rifalazil in Patients with Pulmonary Tuberculosis Reynaldo Dietze, Luciléia Teixeira, Lia Márcia Canedo Rocha, Moisés Palaci, John L. Johnson, Charles Wells, Lynn Rose, Kathleen Eisenach, and Jerrold J. Ellner Antimicrob. Agents Chemother. July 2001 45: 1972-1976; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Prospective Study of Candida Species in Patients at a Comprehensive Cancer Center Amar Safdar, Vishnu Chaturvedi, Emily W. Cross, Steven Park, Edward M. Bernard, Donald Armstrong, and David S. Perlin Antimicrob. Agents Chemother. July 2001 45: 2129-2133; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Clarithromycin Resistance and Eradication of Helicobacter pylori in Children N. Kalach, P. H. Benhamou, F. Campeotto, M. Bergeret, C. Dupont, and J. Raymond Antimicrob. Agents Chemother. July 2001 45: 2134-2135; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Experimental Therapeutics:

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Durability of Anti-Infective Effect of Long-Term Silicone Sheath Catheters Impregnated with Antimicrobial Agents Robert K. Tcholakian and Issam I. Raad Antimicrob. Agents Chemother. July 2001 45: 1990-1993; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pharmacodynamic Assessment of Gatifloxacin against Streptococcus pneumoniae Holly M. Mattoes, Maryanne Banevicius, Dadong Li, Christina Turley, Dawei Xuan, Charles H. Nightingale, and David P. Nicolau Antimicrob. Agents Chemother. July 2001 45: 2092-2097; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Activity of LY333328 in Experimental Meningitis Caused by a Streptococcus pneumoniae Strain Susceptible to Penicillin Joachim Gerber, Alexander Smirnov, Andreas Wellmer, Jasmin Ragheb, Juliane Prange, Eckhardt Schütz, Klaus Wettich, Siegfried Kalich, and Roland Nau Antimicrob. Agents Chemother. July 2001 45: 2169-2172; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Mechanisms of Action:

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Novel Bifunctional Inhibitor of Xylanase and Aspartic Protease: Implications for Inhibition of Fungal Growth Chandravanu Dash, Absar Ahmad, Devyani Nath, and Mala Rao Antimicrob. Agents Chemother. July 2001 45: 2008-2017; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Inhibition of Fumarate Reductase in Leishmania major and L. donovani by Chalcones Ming Chen, Lin Zhai, Søren Brøgger Christensen, Thor G. Theander, and Arsalan Kharazmi Antimicrob. Agents Chemother. July 2001 45: 2023-2029; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antimonial-Mediated DNA Fragmentation in Leishmania infantum Amastigotes Denis Sereno, Philippe Holzmuller, Isabelle Mangot, Gérard Cuny, Ali Ouaissi, and Jean-Loup Lemesre Antimicrob. Agents Chemother. July 2001 45: 2064-2069; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Antiviral Agents:

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Effect of Famciclovir on Herpes Simplex Virus Type 1 Corneal Disease and Establishment of Latency in Rabbits Jeannette M. Loutsch, Bruno Sainz, Jr., Mary E. Marquart, Xiaodong Zheng, Prabakaran Kesavan, Shiro Higaki, James M. Hill, and Ruth Tal-Singer Antimicrob. Agents Chemother. July 2001 45: 2044-2053; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Induction of Epstein-Barr Virus Kinases To Sensitize Tumor Cells to Nucleoside Analogues Stacy M. Moore, Jennifer S. Cannon, Yvette C. Tanhehco, Fayez M. Hamzeh, and Richard F. Ambinder Antimicrob. Agents Chemother. July 2001 45: 2082-2091; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pharmacodynamic Evaluation of RWJ-270201, a Novel Neuraminidase Inhibitor, in a Lethal Murine Model of Influenza Predicts Efficacy for Once-Daily Dosing G. L. Drusano, S. L. Preston, D. Smee, K. Bush, K. Bailey, and R. W. Sidwell Antimicrob. Agents Chemother. July 2001 45: 2115-2118; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Biochemical Mechanism of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Resistance to Stavudine Johan Lennerstrand, David K. Stammers, and Brendan A. Larder Antimicrob. Agents Chemother. July 2001 45: 2144-2146; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Letters:

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Vancomycin Resistance Plasmid in Enterococcus faecalis That Encodes Sensitivity to a Sex Pheromone Also Produced by Staphylococcus aureus Sasha A. Showsh, Erika H. De Boever, and Don B. Clewell Antimicrob. Agents Chemother. July 2001 45: 2177-2178; [Full Text] [PDF] [Reprints and Permissions]

Inhibitor-Resistant TEM-33 -Lactamase in a Shigella sonnei Isolate D. Sirot, C. Chanal, R. Bonnet, C. De Champs, J. Sirot, and L. Bret Antimicrob. Agents Chemother. July 2001 45: 2179-2180; [Full Text] [PDF] [Reprints and Permissions]

Update on Rifampin Resistance in the Legionellaceae Annerose Serr, Barbara F. Koenig, Markus Heep, Kim Nielsen, and Jette Marie Bangsborg Antimicrob. Agents Chemother. July 2001 45: 2181-2182; [Full Text] [PDF] [Reprints and Permissions]

Levofloxacin-Resistant Streptococcus pneumoniae: Second Look Clyde Thornsberry, James A. Karlowsky, Daniel F. Sahm, James H. Jorgensen, L. M. Weigel, J. M. Swenson, C. G. Whitney, F. C. Tenover, and M. J. Ferraro Antimicrob. Agents Chemother. July 2001 45: 2183-2184; [Full Text] [PDF] [Reprints and Permissions]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.