Contents: August 2001, Volume 45, Issue 8        Minireviews        Mechanisms of Resistance        Experimental Therapeutics        Susceptibility        Antiviral Agents        Mechanisms of Action        Clinical Therapeutics        Letters        Author's Correction Other Issues

Table of Contents

[Index by Author]

To see an article, click its [Full Text], [Abstract] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

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Minireviews:

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Clinical and Experimental Advances in Treatment of Visceral Leishmaniasis Henry W. Murray Antimicrob. Agents Chemother. August 2001 45: 2185-2197; [Full Text] [PDF] [Reprints and Permissions]

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Mechanisms of Resistance:

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Growth and Development of Tetracycline-Resistant Chlamydia suis J. Lenart, A. A. Andersen, and D. D. Rockey Antimicrob. Agents Chemother. August 2001 45: 2198-2203; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Metallo--Lactamases in Clinical Pseudomonas Isolates in Taiwan and Identification of VIM-3, a Novel Variant of the VIM-2 Enzyme Jing-Jou Yan, Po-Ren Hsueh, Wen-Chien Ko, Kwen-Tay Luh, Shu-Huei Tsai, Hsiu-Mei Wu, and Jiunn-Jong Wu Antimicrob. Agents Chemother. August 2001 45: 2224-2228; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Type II Topoisomerase Mutations in Fluoroquinolone-Resistant Clinical Strains of Pseudomonas aeruginosa Isolated in 1998 and 1999: Role of Target Enzyme in Mechanism of Fluoroquinolone Resistance Takaaki Akasaka, Mayumi Tanaka, Akihito Yamaguchi, and Kenichi Sato Antimicrob. Agents Chemother. August 2001 45: 2263-2268; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Novel Cefotaximase (CTX-M-16) with Increased Catalytic Efficiency Due to Substitution Asp-240Gly R. Bonnet, C. Dutour, J. L. M. Sampaio, C. Chanal, D. Sirot, R. Labia, C. De Champs, and J. Sirot Antimicrob. Agents Chemother. August 2001 45: 2269-2275; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Macrolide Resistance Gene mreA of Streptococcus agalactiae Encodes a Flavokinase Gervais Clarebout, Corinne Villers, and Roland Leclercq Antimicrob. Agents Chemother. August 2001 45: 2280-2286; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Novel Class A -Lactamase Sed-1 from Citrobacter sedlakii: Genetic Diversity of -Lactamases within the Citrobacter Genus Stephanie Petrella, Dominique Clermont, Isabelle Casin, Vincent Jarlier, and Wladimir Sougakoff Antimicrob. Agents Chemother. August 2001 45: 2287-2298; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Large Drug Resistance Virulence Plasmids of Clinical Isolates of Salmonella enterica Serovar Choleraesuis Chishih Chu, Cheng-Hsun Chiu, Wan-Yu Wu, Chi-Hong Chu, Tsui-Ping Liu, and Jonathan T. Ou Antimicrob. Agents Chemother. August 2001 45: 2299-2303; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Molecular Characterization of Chromosomal Class C -Lactamase and Its Regulatory Gene in Ochrobactrum anthropi David Nadjar, Roger Labia, Claude Cerceau, Chantal Bizet, Alain Philippon, and Guillaume Arlet Antimicrob. Agents Chemother. August 2001 45: 2324-2330; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mutation in Serratia marcescens AmpC -Lactamase Producing High-Level Resistance to Ceftazidime and Cefpirome Alessandro Raimondi, Francesca Sisto, and Hiroshi Nikaido Antimicrob. Agents Chemother. August 2001 45: 2331-2339; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Resistance to Moxifloxacin in Toxigenic Clostridium difficile Isolates Is Associated with Mutations in gyrA Grit Ackermann, Yajarayma J. Tang, Robert Kueper, Peter Heisig, Arne C. Rodloff, Joseph Silva, Jr., and Stuart H. Cohen Antimicrob. Agents Chemother. August 2001 45: 2348-2353; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Identification of a Plasmid Encoding SHV-12, TEM-1, and a Variant of IMP-2 Metallo--Lactamase, IMP-8, from a Clinical Isolate of Klebsiella pneumoniae Jing-Jou Yan, Wen-Chien Ko, and Jiunn-Jong Wu Antimicrob. Agents Chemother. August 2001 45: 2368-2371; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Prevalence of Macrolide Resistance Genes in Clinical Isolates of the Streptococcus anginosus ("S. milleri") Group Jan A. Jacobs, Gilles J. van Baar, Nancy H. H. J. London, Jeroen H. T. Tjhie, Leo M. Schouls, and Ellen E. Stobberingh Antimicrob. Agents Chemother. August 2001 45: 2375-2377; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mutation in the DNA Gyrase A Gene of Escherichia coli That Expands the Quinolone Resistance-Determining Region S. Marvin Friedman, Tao Lu, and Karl Drlica Antimicrob. Agents Chemother. August 2001 45: 2378-2380; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Nonenzymatic Chloramphenicol Resistance Mediated by IncC Plasmid R55 Is Encoded by a floR Gene Variant Axel Cloeckaert, Sylvie Baucheron, and Elisabeth Chaslus-Dancla Antimicrob. Agents Chemother. August 2001 45: 2381-2382; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Cloning and Biochemical Characterization of a Class A -Lactamase from Prevotella intermedia I. Madinier, T. Fosse, J. Giudicelli, and R. Labia Antimicrob. Agents Chemother. August 2001 45: 2386-2389; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Alterations in MurM, a Cell Wall Muropeptide Branching Enzyme, Increase High-Level Penicillin and Cephalosporin Resistance in Streptococcus pneumoniae Anthony M. Smith and Keith P. Klugman Antimicrob. Agents Chemother. August 2001 45: 2393-2396; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antibiotic Susceptibility and Mechanisms of Erythromycin Resistance in Clinical Isolates of Streptococcus agalactiae: French Multicenter Study Dany De Mouy, Jean-Didier Cavallo, Roland Leclercq, Roland Fabre, and The Aforcopi-Bio Network Antimicrob. Agents Chemother. August 2001 45: 2400-2402; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Experimental Therapeutics:

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In Vitro Activity of Gemifloxacin (SB-265805, LB20304a) against Legionella pneumophila and Its Pharmacokinetics in Guinea Pigs with L. pneumophila Pneumonia Paul H. Edelstein, Takashi Shinzato, Edward Doyle, and Martha A. C. Edelstein Antimicrob. Agents Chemother. August 2001 45: 2204-2209; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Telithromycin Is Active against Mycobacterium avium in Mice despite Lacking Significant Activity in Standard In Vitro and Macrophage Assays and Is Associated with Low Frequency of Resistance during Treatment Luiz E. Bermudez, Clark B. Inderlied, Peter Kolonoski, Martin Wu, Priscilla Aralar, and Lowell S. Young Antimicrob. Agents Chemother. August 2001 45: 2210-2214; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Efficacy of Linezolid in Treatment of Experimental Endocarditis Caused by Methicillin-Resistant Staphylococcus aureus Charlene F. Dailey, Christine L. Dileto-Fang, Lewis V. Buchanan, Martha P. Oramas-Shirey, Donald H. Batts, Charles W. Ford, and John K. Gibson Antimicrob. Agents Chemother. August 2001 45: 2304-2308; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

GT160-246, a Toxin Binding Polymer for Treatment of Clostridium difficile Colitis Caroline B. Kurtz, E. Pat Cannon, Alex Brezzani, Mary Pitruzzello, Carol Dinardo, Emilie Rinard, David W. K. Acheson, Richard Fitzpatrick, Pamela Kelly, Keith Shackett, Andrew T. Papoulis, Philip J. Goddard, Robert H. Barker, Jr., Gerard P. Palace, and Jeffrey D. Klinger Antimicrob. Agents Chemother. August 2001 45: 2340-2347; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Influence of Liposomal Amphotericin B on CD8 T-Cell Function Marianne Kretschmar, Gernot Geginat, Thomas Bertsch, Simon Walter, Herbert Hof, and Thomas Nichterlein Antimicrob. Agents Chemother. August 2001 45: 2383-2385; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Susceptibility:

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Kinetic Study of Two Novel Enantiomeric Tricyclic -Lactams Which Efficiently Inactivate Class C -Lactamases Mateja Vilar, Moreno Galleni, Tom Solmajer, Boris Turk, Jean-Marie Frère, and André Matagne Antimicrob. Agents Chemother. August 2001 45: 2215-2223; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Natural Antibiotic Susceptibilities of Edwardsiella tarda, E. ictaluri, and E. hoshinae Ingo Stock and Bernd Wiedemann Antimicrob. Agents Chemother. August 2001 45: 2245-2255; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Echinococcus multilocularis Alkaline Phosphatase as a Marker for Metacestode Damage Induced by In Vitro Drug Treatment with Albendazole Sulfoxide and Albendazole Sulfone Marianne Stettler, Mar Siles-Lucas, Elisabeth Sarciron, Philippe Lawton, Bruno Gottstein, and Andrew Hemphill Antimicrob. Agents Chemother. August 2001 45: 2256-2262; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Kappacin, a Novel Antibacterial Peptide from Bovine Milk Marina Malkoski, Stuart G. Dashper, Neil M. O'Brien-Simpson, Gert H. Talbo, Mary Macris, Keith J. Cross, and Eric C. Reynolds Antimicrob. Agents Chemother. August 2001 45: 2309-2315; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activities of ABT-773, a New Ketolide, against Aerobic and Anaerobic Pathogens Isolated from Antral Sinus Puncture Specimens from Patients with Sinusitis Ellie J. C. Goldstein, Georg Conrads, Diane M. Citron, C. Vreni Merriam, Yumi Warren, and Kerin Tyrrell Antimicrob. Agents Chemother. August 2001 45: 2363-2367; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activities of MK-0826 and 16 Other Antimicrobials against Bacteroides fragilis Group Strains Carmen Betriu, Ana Sánchez, María Luisa Palau, María Gómez, and Juan J. Picazo Antimicrob. Agents Chemother. August 2001 45: 2372-2374; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Activities of Gemifloxacin and Five Other Antimicrobial Agents against Listeria monocytogenes and Coryneform Bacteria Isolated from Clinical Samples Luis Martínez-Martínez, Providencia Joyanes, Ana I. Suárez, and Evelio J. Perea Antimicrob. Agents Chemother. August 2001 45: 2390-2392; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Antiviral Agents:

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Sodium Lauryl Sulfate Abrogates Human Immunodeficiency Virus Infectivity by Affecting Viral Attachment Julie Bestman-Smith, Jocelyne Piret, André Désormeaux, Michel J. Tremblay, Rabeea F. Omar, and Michel G. Bergeron Antimicrob. Agents Chemother. August 2001 45: 2229-2237; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Variants Other than Aspartic Acid at Codon 69 of the Human Immunodeficiency Virus Type 1 Reverse Transcriptase Gene Affect Susceptibility to Nucleoside Analogs Mark A. Winters and Thomas C. Merigan Antimicrob. Agents Chemother. August 2001 45: 2276-2279; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Intravenous Infusion of Cereport Increases Uptake and Efficacy of Acyclovir in Herpes Simplex Virus-Infected Rat Brains Deborah J. Bidanset, Laurent Placidi, Rachel Rybak, Joyce Palmer, Jean-Pierre Sommadossi, and Earl R. Kern Antimicrob. Agents Chemother. August 2001 45: 2316-2323; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Mechanisms of Action:

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Overexpression and Characterization of the Chromosomal Aminoglycoside 2'-N-Acetyltransferase of Providencia stuartii Kristyn Franklin and Anthony J. Clarke Antimicrob. Agents Chemother. August 2001 45: 2238-2244; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Immunoprecipitation of [3H]Dihydroartemisinin Translationally Controlled Tumor Protein (TCTP) Adducts from Plasmodium falciparum-Infected Erythrocytes by Using Anti-TCTP Antibodies Jamaree Bhisutthibhan and Steven R. Meshnick Antimicrob. Agents Chemother. August 2001 45: 2397-2399; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Clinical Therapeutics:

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Clearance of Fungal Burden during Treatment of Disseminated Histoplasmosis with Liposomal Amphotericin B versus Itraconazole L. Joseph Wheat, Gretchen Cloud, Philip C. Johnson, Patricia Connolly, Mitchell Goldman, Ann Le Monte, Deanna E. Fuller, Thomas E. Davis, Richard Hafner, The AIDS Clinical Trials Group, and The Mycoses Study Group Of NIAID Antimicrob. Agents Chemother. August 2001 45: 2354-2357; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Once-Daily Oral Gatifloxacin versus Oral Levofloxacin in Treatment of Uncomplicated Skin and Soft Tissue Infections: Double-Blind, Multicenter, Randomized Study Gary A. Tarshis, Barry M. Miskin, Terry M. Jones, John Champlin, Kevin J. Wingert, Jeanne D. Breen, and Michael J. Brown Antimicrob. Agents Chemother. August 2001 45: 2358-2362; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Letters:

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In Vitro Activities of Mitomycin C against Growing and Hypoxic Dormant Tubercle Bacilli H. L. Peh, A. Toh, B. Murugasu-Oei, and T. Dick Antimicrob. Agents Chemother. August 2001 45: 2403-2404; [Full Text] [PDF] [Reprints and Permissions]

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Author's Correction:

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Circulating Metabolites of the Human Immunodeficiency Virus Protease Inhibitor Nelfinavir in Humans: Structural Identification, Levels in Plasma, and Antiviral Activities Kanyin E. Zhang, Ellen Wu, Amy K. Patick, Bradley Kerr, Mark Zorbas, Angela Lankford, Takuo Kobayashi, Yuki Maeda, Bhasker Shetty, and Stephanie Webber Antimicrob. Agents Chemother. August 2001 45: 2405 [Full Text] [PDF] [Reprints and Permissions]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.