Contents: January 2002, Volume 46, Issue 1        Minireviews        Experimental Therapeutics        Mechanisms of Resistance        Pharmacology        Susceptibility        Mechanisms of Action        Antiviral Agents        Clinical Therapeutics        Errata Other Issues

Table of Contents

[Index by Author]

To see an article, click its [Full Text], [Abstract] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

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Minireviews:

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Plasmid-Determined AmpC-Type ß-Lactamases Alain Philippon, Guillaume Arlet, and George A. Jacoby Antimicrob. Agents Chemother. January 2002 46: 1-11; [Full Text] [PDF] [Reprints and Permissions]

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Experimental Therapeutics:

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Antifungal Efficacy of Caspofungin (MK-0991) in Experimental Pulmonary Aspergillosis in Persistently Neutropenic Rabbits: Pharmacokinetics, Drug Disposition, and Relationship to Galactomannan Antigenemia Ruta Petraitiene, Vidmantas Petraitis, Andreas H. Groll, Tin Sein, Robert L. Schaufele, Andrea Francesconi, John Bacher, Nilo A. Avila, and Thomas J. Walsh Antimicrob. Agents Chemother. January 2002 46: 12-23; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Novel Synthetic Polyamines Are Effective in the Treatment of Experimental Microsporidiosis, an Opportunistic AIDS-Associated Infection Cyrus J. Bacchi, Louis M. Weiss, Schenella Lane, Benjamin Frydman, Aldonia Valasinas, Venodhar Reddy, Jerry S. Sun, Laurence J. Marton, Imitiaz A. Khan, Magali Moretto, Nigel Yarlett, and Murray Wittner Antimicrob. Agents Chemother. January 2002 46: 55-61; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pharmacodynamics of Gatifloxacin against Streptococcus pneumoniae in an In Vitro Pharmacokinetic Model: Impact of Area under the Curve/MIC Ratios on Eradication Philip D. Lister Antimicrob. Agents Chemother. January 2002 46: 69-74; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Single-Dose Intraperitoneal Magainins Improve Survival in a Gram-Negative-Pathogen Septic Shock Rat Model Oscar Cirioni, Andrea Giacometti, Roberto Ghiselli, Federico Mocchegiani, Anna Fineo, Fiorenza Orlando, Maria Simona Del Prete, Marco Rocchi, Vittorio Saba, and Giorgio Scalise Antimicrob. Agents Chemother. January 2002 46: 101-104; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Carrier-Mediated Partitioning of Artemisinin into Plasmodium falciparum-Infected Erythrocytes Nehal Vyas, Bonnie A. Avery, Mitchell A. Avery, and Christy M. Wyandt Antimicrob. Agents Chemother. January 2002 46: 105-109; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Effects of Flavophospholipol on Resistance in Fecal Escherichia coli and Enterococci of Fattening P A. E. van den Bogaard, M. Hazen, M. Hoyer, P. Oostenbach, and E. E. Stobberingh Antimicrob. Agents Chemother. January 2002 46: 110-118; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Efficacy of Short-Course Ceftriaxone Therapy for Borrelia burgdorferi Infection in C3H Mice Charles Pavia, Mario A. Inchiosa, Jr, and Gary P. Wormser Antimicrob. Agents Chemother. January 2002 46: 132-134; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Optimization of Xanthones for Antimalarial Activity: the 3,6-Bis--Diethylaminoalkoxyxanthone Series Jane Xu Kelly, Rolf Winter, David H. Peyton, David J. Hinrichs, and Michael Riscoe Antimicrob. Agents Chemother. January 2002 46: 144-150; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

BAL9141, a Novel Extended-Spectrum Cephalosporin Active against Methicillin-Resistant Staphylococcus aureus in Treatment of Experimental Endocarditis J. M. Entenza, P. Hohl, I. Heinze-Krauss, M. P. Glauser, and P. Moreillon Antimicrob. Agents Chemother. January 2002 46: 171-177; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Efficacies of BMS 284756 against Penicillin-Sensitive, Penicillin-Resistant, and Quinolone-Resistant Pneumococci in Experimental Meningitis Philippe Cottagnoud, Fernando Acosta, Marianne Cottagnoud, Marc Pfister, and Martin G. Täuber Antimicrob. Agents Chemother. January 2002 46: 184-187; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Gentamicin Increases the Efficacy of Vancomycin against Penicillin-Resistant Pneumococci in the Rabbit Meningitis Model Philippe Cottagnoud, Cynthia M. Gerber, Marianne Cottagnoud, and Martin G. Täuber Antimicrob. Agents Chemother. January 2002 46: 188-190; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Gatifloxacin Efficacy in Treatment of Experimental Methicillin-Sensitive Staphylococcus aureus-Induced Osteomyelitis in Rabbits Mark E. Shirtliff, Jason H. Calhoun, and Jon T. Mader Antimicrob. Agents Chemother. January 2002 46: 231-233; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Combination Therapy with Indolylquinoline Derivative and Sodium Antimony Gluconate Cures Established Visceral Leishmaniasis in Hamsters Chiranjib Pal, Mousumi Raha, Anirban Basu, Keshab Chandra Roy, Anasuya Gupta, Monidipa Ghosh, Niranjan Prasad Sahu, Sukdeb Banerjee, Nirup Bikash Mandal, and Santu Bandyopadhyay Antimicrob. Agents Chemother. January 2002 46: 259-261; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pharmacodynamic Interaction of Doxycycline and Artemisinin in Plasmodium falciparum Ulrike Sponer, Somsak Prajakwong, Gerhard Wiedermann, Herwig Kollaritsch, Gunther Wernsdorfer, and Walther H. Wernsdorfer Antimicrob. Agents Chemother. January 2002 46: 262-264; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Mechanisms of Resistance:

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Conversion of Oxacillin-Resistant Staphylococci from Heterotypic to Homotypic Resistance Expression J. E. Finan, A. E. Rosato, T. M. Dickinson, D. Ko, and Gordon L. Archer Antimicrob. Agents Chemother. January 2002 46: 24-30; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Increased Glycan Chain Length Distribution and Decreased Susceptibility to Moenomycin in a Vancomycin-Resistant Staphylococcus aureus Mutant Hitoshi Komatsuzawa, Kouji Ohta, Sakuo Yamada, Kerstin Ehlert, Harald Labischinski, Junko Kajimura, Tamaki Fujiwara, and Motoyuki Sugai Antimicrob. Agents Chemother. January 2002 46: 75-81; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

D-Ala:D-Ala Ligase Gene Flanking the vanC Cluster: Evidence for Presence of Three Ligase Genes in Vancomycin-Resistant Enterococcus gallinarum BM4174 Ole-Herman Ambúr, Peter E. Reynolds, and Cesar A. Arias Antimicrob. Agents Chemother. January 2002 46: 95-100; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Diversity of Ribosomal Mutations Conferring Resistance to Macrolides, Clindamycin, Streptogramin, and Telithromycin in Streptococcus pneumoniae Annie Canu, Brigitte Malbruny, Maëlle Coquemont, Todd A. Davies, Peter C. Appelbaum, and Roland Leclercq Antimicrob. Agents Chemother. January 2002 46: 125-131; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Countrywide Spread of CTX-M-3 Extended-Spectrum ß-Lactamase-Producing Microorganisms of the Family Enterobacteriaceae in Poland Anna Baraniak, Janusz Fiett, Agnieszka Sulikowska, Waleria Hryniewicz, and Marek Gniadkowski Antimicrob. Agents Chemother. January 2002 46: 151-159; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Interaction of Common Azole Antifungals with P Glycoprotein Er-jia Wang, Karen Lew, Christopher N. Casciano, Robert P. Clement, and William W. Johnson Antimicrob. Agents Chemother. January 2002 46: 160-165; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pfmdr1 Alleles and Response to Ultralow-Dose Mefloquine Treatment in Gabonese Patients Denise P. Mawili-Mboumba, Jürgen F. J. Kun, Bertrand Lell, Peter G. Kremsner, and Francine Ntoumi Antimicrob. Agents Chemother. January 2002 46: 166-170; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Differential Expression of Methicillin Resistance by Different Biofilm-Negative Staphylococcus epidermidis Transposon Mutant Classes Dietrich Mack, Axel Sabottke, Sabine Dobinsky, Holger Rohde, Matthias A. Horstkotte, and Johannes K.-M. Knobloch Antimicrob. Agents Chemother. January 2002 46: 178-183; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Occurrence of Extended-Spectrum ß-Lactamases in Members of the Family Enterobacteriaceae in Italy: Implications for Resistance to ß-Lactams and Other Antimicrobial Drugs T. Spanu, F. Luzzaro, M. Perilli, G. Amicosante, A. Toniolo, and G. Fadda Antimicrob. Agents Chemother. January 2002 46: 196-202; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

New erm Gene in Staphylococcus aureus Clinical Isolates Mayumi Matsuoka, Matsuhisa Inoue, Yoshinori Nakajima, and Yoshihiro Endo Antimicrob. Agents Chemother. January 2002 46: 211-215; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Postneurosurgical Meningitis Due to Proteus penneri with Selection of a Ceftriaxone-Resistant Isolate: Analysis of Chromosomal Class A ß-Lactamase HugA and its LysR-Type Regulatory Protein HugR Nadia Liassine, Stéphanie Madec, Béatrice Ninet, Catherine Metral, Martine Fouchereau-Peron, Roger Labia, and Raymond Auckenthaler Antimicrob. Agents Chemother. January 2002 46: 216-219; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Multicenter Study on Spreading of the tet(M) Gene in Tetracycline-Resistant Streptococcus Group G and C Isolates in Argentina P. E. Jeric, H. Lopardo, P. Vidal, S. Arduino, A. Fernandez, B. E. Orman, D. O. Sordelli, and D. Centrón Antimicrob. Agents Chemother. January 2002 46: 239-241; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Nosocomial Outbreak of Carbapenem-Resistant Pseudomonas aeruginosa with a New blaIMP Allele, blaIMP-7 Alan Patrick Gibb, Chanwit Tribuddharat, Richard A. Moore, Thomas J. Louie, Wally Krulicki, David M. Livermore, Marie-France I. Palepou, and Neil Woodford Antimicrob. Agents Chemother. January 2002 46: 255-258; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Pharmacology:

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Pharmacokinetics and Inflammatory Fluid Penetration of Intravenous Daptomycin in Volunteers R. Wise, T. Gee, J. M. Andrews, B. Dvorchik, and G. Marshall Antimicrob. Agents Chemother. January 2002 46: 31-33; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pharmacodynamics of Trovafloxacin and Levofloxacin against Bacteroides fragilis in an In Vitro Pharmacodynamic Model M. L. Peterson, L. B. Hovde, D. H. Wright, G. H. Brown, A. D. Hoang, and J. C. Rotschafer Antimicrob. Agents Chemother. January 2002 46: 203-210; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Single-Dose Pharmacokinetics and Penetration of BMS 284756 into an Inflammatory Exudate R. Wise, T. Gee, G. Marshall, and J. M. Andrews Antimicrob. Agents Chemother. January 2002 46: 242-244; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Susceptibility:

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In Vitro Microbicidal Activities of Cecropin Peptides D2A21 and D4E1 and Gel Formulations Containing 0.1 to 2% D2A21 against Chlamydia trachomatis L. M. Ballweber, J. E. Jaynes, W. E. Stamm, and M. F. Lampe Antimicrob. Agents Chemother. January 2002 46: 34-41; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antipneumococcal Activity of Ertapenem (MK-0826) Compared to Those of Other Agents Glenn A. Pankuch, Todd A. Davies, Michael R. Jacobs, and Peter C. Appelbaum Antimicrob. Agents Chemother. January 2002 46: 42-46; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activities of New and Conventional Antifungal Agents against Clinical Scedosporium Isolates Joseph Meletiadis, Jacques F. G. M. Meis, Johan W. Mouton, Juan Luis Rodriquez-Tudela, J. Peter Donnelly, and Paul E. Verweij Antimicrob. Agents Chemother. January 2002 46: 62-68; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Prevalence of Single Mutations in Topoisomerase Type II Genes among Levofloxacin-Susceptible Clinical Strains of Streptococcus pneumoniae Isolated in the United States in 1992 to 1996 and 1999 to 2000 Todd A. Davies, Alan Evangelista, Sharon Pfleger, Karen Bush, Daniel F. Sahm, and Raul Goldschmidt Antimicrob. Agents Chemother. January 2002 46: 119-124; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Bactericidal Activities of BMS-284756, a Novel Des-F(6)-Quinolone, against Staphylococcus aureus Strains with Topoisomerase Mutations Laura E. Lawrence, MaryBeth Frosco, Brenda Ryan, Susan Chaniewski, Hyekyung Yang, David C. Hooper, and John F. Barrett Antimicrob. Agents Chemother. January 2002 46: 191-195; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Antianaerobic Activity of Ertapenem (MK-0826) Compared to Seven Other Compounds Dianne B. Hoellman, Linda M. Kelly, Kim Credito, Lauren Anthony, Lois M. Ednie, Michael R. Jacobs, and Peter C. Appelbaum Antimicrob. Agents Chemother. January 2002 46: 220-224; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Potentiation of Antibiotic Activities by a Catecholate Iron Chelator against Chloroquine-Resistant Plasmodium falciparum Bruno Pradines, Florence Ramiandrasoa, Jean Marc Rolain, Christophe Rogier, Joel Mosnier, William Daries, Thierry Fusai, Gerhard Kunesch, Jacques Le Bras, and Daniel Parzy Antimicrob. Agents Chemother. January 2002 46: 225-228; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antimicrobial Activities of BMS-284756 Compared with Those of Fluoroquinolones and ß-Lactams against Gram-Positive Clinical Isolates Matteo Bassetti, Louise M. Dembry, Patricia A. Farrel, Deborah A. Callan, and Vincent T. Andriole Antimicrob. Agents Chemother. January 2002 46: 234-238; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Synergy of Caspofungin and Amphotericin B against Aspergillus and Fusarium spp. Sevtap Arikan, Mario Lozano-Chiu, Victor Paetznick, and John H. Rex Antimicrob. Agents Chemother. January 2002 46: 245-247; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antipneumococcal Activity of BMS 284756 Compared to Those of Six Other Agents Glenn A. Pankuch, Kensuke Nagai, Todd A. Davies, Michael R. Jacobs, and Peter C. Appelbaum Antimicrob. Agents Chemother. January 2002 46: 251-254; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Mechanisms of Action:

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Mycobacterium smegmatis D-Alanine Racemase Mutants Are Not Dependent on D-Alanine for Growth Ofelia Chacon, Zhengyu Feng, N. Beth Harris, Nancy E. Cáceres, L. Garry Adams, and Raúl G. Barletta Antimicrob. Agents Chemother. January 2002 46: 47-54; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Microcin E492 Is an Unmodified Peptide Related in Structure to Colicin V Anne-Marie Pons, Nathalie Zorn, David Vignon, François Delalande, Alain Van Dorsselaer, and Gilles Cottenceau Antimicrob. Agents Chemother. January 2002 46: 229-230; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Antiviral Agents:

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Potent Efficacy of Entecavir (BMS-200475) in a Duck Model of Hepatitis B Virus Replication Patricia L. Marion, Felix H. Salazar, Mark A. Winters, and Richard J. Colonno Antimicrob. Agents Chemother. January 2002 46: 82-88; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Prediction of Abacavir Resistance from Genotypic Data: Impact of Zidovudine and Lamivudine Resistance In Vitro and In Vivo Hauke Walter, Barbara Schmidt, Marianne Werwein, Eva Schwingel, and Klaus Korn Antimicrob. Agents Chemother. January 2002 46: 89-94; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Development of Enzymatic Assays for Quantification of Intracellular Lamivudine and Carbovir Triphosphate Levels in Peripheral Blood Mononuclear Cells from Human Immunodeficiency Virus-Infected Patients Stephen Kewn, Patrick G. Hoggard, Sean D. Sales, Kevin Jones, Bridget Maher, Saye H. Khoo, and David J. Back Antimicrob. Agents Chemother. January 2002 46: 135-143; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Clinical Therapeutics:

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Antigen Clearance during Treatment of Disseminated Histoplasmosis with Itraconazole versus Fluconazole in Patients with AIDS L. Joseph Wheat, Patricia Connolly, Nicholas Haddad, Ann Le Monte, Edward Brizendine, and Richard Hafner Antimicrob. Agents Chemother. January 2002 46: 248-250; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Errata:

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ATP Synthase Is Necessary for Microcin H47 Antibiotic Action Mónica Trujillo, Eliana Rodríguez, and Magela Laviña Antimicrob. Agents Chemother. January 2002 46: 265 [Full Text] [PDF] [Reprints and Permissions]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.