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Mechanisms of Action:

Daisuke Kobayashi, Kei Kondo, Nobuyuki Uehara, Seiko Otokozawa, Naoki Tsuji, Atsuhito Yagihashi, and Naoki Watanabe

Endogenous Reactive Oxygen Species Is an Important Mediator of Miconazole Antifungal Effect
Antimicrob. Agents Chemother. 2002 46: 3113-3117. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

David J. Payne, William H. Miller, Valerie Berry, John Brosky, Walter J. Burgess, Emile Chen, Walter E. DeWolf, Jr., Andrew P. Fosberry, Rebecca Greenwood, Martha S. Head, Dirk A. Heerding, Cheryl A. Janson, Deborah D. Jaworski, Paul M. Keller, Peter J. Manley, Terrance D. Moore, Kenneth A. Newlander, Stewart Pearson, Brian J. Polizzi, Xiayang Qiu, Stephen F. Rittenhouse, Courtney Slater-Radosti, Kevin L. Salyers, Mark A. Seefeld, Martin G. Smyth, Dennis T. Takata, Irene N. Uzinskas, Kalindi Vaidya, Nicola G. Wallis, Scott B. Winram, Catherine C. K. Yuan, and William F. Huffman

Discovery of a Novel and Potent Class of FabI-Directed Antibacterial Agents
Antimicrob. Agents Chemother. 2002 46: 3118-3124. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

John T. Hancock, Vyv Salisbury, Maria Cristina Ovejero-Boglione, Robert Cherry, Catherine Hoare, Robert Eisenthal, and Roger Harrison

Antimicrobial Properties of Milk: Dependence on Presence of Xanthine Oxidase and Nitrite
Antimicrob. Agents Chemother. 2002 46: 3308-3310. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Resistance:

Ireena Dutta and Peter E. Reynolds

Biochemical and Genetic Characterization of the vanC-2 Vancomycin Resistance Gene Cluster of Enterococcus casseliflavus ATCC 25788
Antimicrob. Agents Chemother. 2002 46: 3125-3132. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

George Tegos, Frank R. Stermitz, Olga Lomovskaya, and Kim Lewis

Multidrug Pump Inhibitors Uncover Remarkable Activity of Plant Antimicrobials
Antimicrob. Agents Chemother. 2002 46: 3133-3141. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

S. Pereyre, P. Gonzalez, B. de Barbeyrac, A. Darnige, H. Renaudin, A. Charron, S. Raherison, C. Bébéar, and C. M. Bébéar

Mutations in 23S rRNA Account for Intrinsic Resistance to Macrolides in Mycoplasma hominis and Mycoplasma fermentans and for Acquired Resistance to Macrolides in M. hominis
Antimicrob. Agents Chemother. 2002 46: 3142-3150. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Boudewijn L. M. de Jonge, Douglas Gage,, and Naxing Xu

The Carboxyl Terminus of Peptidoglycan Stem Peptides Is a Determinant for Methicillin Resistance in Staphylococcus aureus
Antimicrob. Agents Chemother. 2002 46: 3151-3155. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Laura Briñas, Myriam Zarazaga, Yolanda Sáenz, Fernanda Ruiz-Larrea, and Carmen Torres

ß-Lactamases in Ampicillin-Resistant Escherichia coli Isolates from Foods, Humans, and Healthy Animals
Antimicrob. Agents Chemother. 2002 46: 3156-3163. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Anne-Sophie Morin, Laurent Poirel, Francine Mory, Roger Labia, and Patrice Nordmann

Biochemical-Genetic Analysis and Distribution of DES-1, an Ambler Class A Extended-Spectrum ß-Lactamase from Desulfovibrio desulfuricans
Antimicrob. Agents Chemother. 2002 46: 3215-3222. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Samuel Bellais, Delphine Girlich, Amal Karim, and Patrice Nordmann

EBR-1, a Novel Ambler Subclass B1 ß-Lactamase from Empedobacter brevis
Antimicrob. Agents Chemother. 2002 46: 3223-3227. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kenji Hirose, Ai Hashimoto, Kazumichi Tamura, Yoshiaki Kawamura, Takayuki Ezaki, Hiroko Sagara, and Haruo Watanabe

DNA Sequence Analysis of DNA Gyrase and DNA Topoisomerase IV Quinolone Resistance-Determining Regions of Salmonella enterica Serovar Typhi and Serovar Paratyphi A
Antimicrob. Agents Chemother. 2002 46: 3249-3252. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hae Kyung Lee, Sergei B. Vakulenko, Don B. Clewell, Stephen A. Lerner, and Joseph W. Chow

Mutations in the aph(2")-Ic Gene Are Responsible for Increased Levels of Aminoglycoside Resistance
Antimicrob. Agents Chemother. 2002 46: 3253-3256. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Takeshi Ikeda and Fuminobu Yoshimura

A Resistance-Nodulation-Cell Division Family Xenobiotic Efflux Pump in an Obligate Anaerobe, Porphyromonas gingivalis
Antimicrob. Agents Chemother. 2002 46: 3257-3260. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kimberly A. Nichol, George G. Zhanel, and Daryl J. Hoban

Penicillin-Binding Protein 1A, 2B, and 2X Alterations in Canadian Isolates of Penicillin-Resistant Streptococcus pneumoniae
Antimicrob. Agents Chemother. 2002 46: 3261-3264. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

S. Corvec, N. Caroff, E. Espaze, J. Marraillac, and A. Reynaud

-11 Mutation in the ampC Promoter Increasing Resistance to ß-Lactams in a Clinical Escherichia coli Strain
Antimicrob. Agents Chemother. 2002 46: 3265-3267. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Siaw Eng Ho, Geetha Subramaniam, Selvi Palasubramaniam, and Parasakthi Navaratnam

Carbapenem-Resistant Pseudomonas aeruginosa in Malaysia Producing IMP-7 ß-Lactamase
Antimicrob. Agents Chemother. 2002 46: 3286-3287. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Richard Bonnet, Catherine Chanal, Elisabeth Ageron, Danielle Sirot, Christophe De Champs, Patrick Grimont, and Jacques Sirot

Inducible AmpC ß-Lactamase of a New Member Enterobacteriaceae
Antimicrob. Agents Chemother. 2002 46: 3316-3319. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

S. H. Marshall, C. J. Donskey, R. Hutton-Thomas, R. A. Salata, and L. B. Rice

Gene Dosage and Linezolid Resistance in Enterococcus faecium and Enterococcus faecalis
Antimicrob. Agents Chemother. 2002 46: 3334-3336. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Susceptibility:

Richard J. Wallace, Jr., Barbara A. Brown-Elliott, Christopher J. Crist, Linda Mann, and Rebecca W. Wilson

Comparison of the In Vitro Activity of the Glycylcycline Tigecycline (Formerly GAR-936) with Those of Tetracycline, Minocycline, and Doxycycline against Isolates of Nontuberculous Mycobacteria
Antimicrob. Agents Chemother. 2002 46: 3164-3167. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Yigong Ge, Stacey Difuntorum, Sofia Touami, Ian Critchley, Roland Bürli, Vernon Jiang, Ken Drazan, and Heinz Moser

In Vitro Antimicrobial Activity of GSQ1530, a New Heteroaromatic Polycyclic Compound
Antimicrob. Agents Chemother. 2002 46: 3168-3174. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kodjo Ayi, Giuliana Giribaldi, Aleksei Skorokhod, Evelin Schwarzer, Patrick T. Prendergast, and Paolo Arese

16-Bromoepiandrosterone, an Antimalarial Analogue of the Hormone Dehydroepiandrosterone, Enhances Phagocytosis of Ring Stage Parasitized Erythrocytes: a Novel Mechanism for Antimalarial Activity
Antimicrob. Agents Chemother. 2002 46: 3180-3184. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Florence Dzierszinski, Alexandra Coppin, Marlene Mortuaire, Etienne Dewailly, Christian Slomianny, Jean-Claude Ameisen, Frederic DeBels, and Stanislas Tomavo

Ligands of the Peripheral Benzodiazepine Receptor Are Potent Inhibitors of Plasmodium falciparum and Toxoplasma gondii In Vitro
Antimicrob. Agents Chemother. 2002 46: 3197-3207. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Robert S. Liao, Robert P. Rennie, and James A. Talbot

Comparative Evaluation of a New Fluorescent Carboxyfluorescein Diacetate-Modified Microdilution Method for Antifungal Susceptibility Testing of Candida albicans Isolates
Antimicrob. Agents Chemother. 2002 46: 3236-3242. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Amar Safdar, Vishnu Chaturvedi, Brian S. Koll, Davise H. Larone, David S. Perlin, and Donald Armstrong

Prospective, Multicenter Surveillance Study of Candida glabrata: Fluconazole and Itraconazole Susceptibility Profiles in Bloodstream, Invasive, and Colonizing Strains and Differences between Isolates from Three Urban Teaching Hospitals in New York City (Candida Susceptibility Trends Study, 1998 to 1999)
Antimicrob. Agents Chemother. 2002 46: 3268-3272. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

G. M. Eliopoulos, C. B. Wennersten, and R. C. Moellering, Jr.

In Vitro Activity of the New Oxazolidinone AZD2563 against Enterococci
Antimicrob. Agents Chemother. 2002 46: 3273-3275. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

D. R. Snydman, N. V. Jacobus, L. A. McDermott, R. Ruthazer, E. Goldstein, S. Finegold, L. Harrell, D. W. Hecht, S. Jenkins, C. Pierson, R. Venezia, J. Rihs, and S. L. Gorbach

In Vitro Activities of Newer Quinolones against Bacteroides Group Organisms
Antimicrob. Agents Chemother. 2002 46: 3276-3279. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Barbara A. Brown-Elliott, Richard J. Wallace, Jr., Christopher J. Crist, Linda Mann, and Rebecca W. Wilson

Comparison of In Vitro Activities of Gatifloxacin and Ciprofloxacin against Four Taxa of Rapidly Growing Mycobacteria
Antimicrob. Agents Chemother. 2002 46: 3283-3285. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Niki I. Paphitou, Luis Ostrosky-Zeichner, Victor L. Paetznick, Jose R. Rodriguez, Enuo Chen, and John H. Rex

In Vitro Activities of Investigational Triazoles against Fusarium Species: Effects of Inoculum Size and Incubation Time on Broth Microdilution Susceptibility Test Results
Antimicrob. Agents Chemother. 2002 46: 3298-3300. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Shin-ichi Yokota, Kiyoshi Sato, Osamu Kuwahara, Satoshi Habadera, Naoyuki Tsukamoto, Hironori Ohuchi, Hirotsugu Akizawa, Tetsuo Himi, and Nobuhiro Fujii

Fluoroquinolone-Resistant Streptococcus pneumoniae Strains Occur Frequently in Elderly Patients in Japan
Antimicrob. Agents Chemother. 2002 46: 3311-3315. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Javier Afeltra, Eric Dannaoui, Jacques F. G. M. Meis, Juan L. Rodriguez-Tudela, and Paul E. Verweij

In Vitro Synergistic Interaction between Amphotericin B and Pentamidine against Scedosporium prolificans
Antimicrob. Agents Chemother. 2002 46: 3323-3326. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Experimental Therapeutics:

Peter G. Sohnle and Beth L. Hahn

Effect of Prolonged Fluconazole Treatment on Candida albicans in Diffusion Chambers Implanted into Mice
Antimicrob. Agents Chemother. 2002 46: 3175-3179. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Myo-Kyoung Kim, Wen Zhou, Pamela R. Tessier, Dawei Xuan, Min Ye, Charles H. Nightingale, and David P. Nicolau

Bactericidal Effect and Pharmacodynamics of Cethromycin (ABT-773) in a Murine Pneumococcal Pneumonia Model
Antimicrob. Agents Chemother. 2002 46: 3185-3192. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Herve Dega, Abdelhalim Bentoucha, Jerome Robert, Vincent Jarlier, and Jacques Grosset

Bactericidal Activity of Rifampin-Amikacin against Mycobacterium ulcerans in Mice
Antimicrob. Agents Chemother. 2002 46: 3193-3196. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Russell E. Lewis, Randall A. Prince, Jingduan Chi, and Dimitrios P. Kontoyiannis

Itraconazole Preexposure Attenuates the Efficacy of Subsequent Amphotericin B Therapy in a Murine Model of Acute Invasive Pulmonary Aspergillosis
Antimicrob. Agents Chemother. 2002 46: 3208-3214. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Katsunori Yanagihara, Yukihiro Kaneko, Toyomitsu Sawai, Yoshitsugu Miyazaki, Kazuhiro Tsukamoto, Yoichi Hirakata, Kazunori Tomono, Jun-Ichi Kadota, Takayoshi Tashiro, Ikuo Murata, and Shigeru Kohno

Efficacy of Linezolid against Methicillin-Resistant or Vancomycin-Insensitive Staphylococcus aureus in a Model of Hematogenous Pulmonary Infection
Antimicrob. Agents Chemother. 2002 46: 3288-3291. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Fausto G. Araujo, Teri L. Slifer, and Jack S. Remington

Inhibition of Secretion of Interleukin-1 and Tumor Necrosis Factor Alpha by the Ketolide Antibiotic Telithromycin
Antimicrob. Agents Chemother. 2002 46: 3327-3330. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Antiviral Agents:

Saye H. Khoo, Patrick G. Hoggard, Ian Williams, E. Rhiannon Meaden, Philippa Newton, Edmund G. Wilkins, Alan Smith, John F. Tjia, Judy Lloyd, Kevin Jones, Nick Beeching, Peter Carey, Barry Peters, and David J. Back

Intracellular Accumulation of Human Immunodeficiency Virus Protease Inhibitors
Antimicrob. Agents Chemother. 2002 46: 3228-3235. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

H. Kojima, K. D. E. Kaita, K. Hawkins, J. Uhanova, and G. Y. Minuk

Use of Fluoroquinolones in Patients with Chronic Hepatitis C Virus-Induced Liver Failure
Antimicrob. Agents Chemother. 2002 46: 3280-3282. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Wim Pluymers, Godwin Pais, Bénédicte Van Maele, Christophe Pannecouque, Valery Fikkert, Terrence R. Burke, Jr., Erik De Clercq, Myriam Witvrouw, Nouri Neamati, and Zeger Debyser

Inhibition of Human Immunodeficiency Virus Type 1 Integration by Diketo Derivatives
Antimicrob. Agents Chemother. 2002 46: 3292-3297. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ryan Reinke, Deborah J. Lee, and W. Edward Robinson, Jr.

Inhibition of Human Immunodeficiency Virus Type 1 Isolates by the Integrase Inhibitor L-731,988, a Diketo Acid
Antimicrob. Agents Chemother. 2002 46: 3301-3303. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Clinical Therapeutics:

Timothy W. Schacker, Marcus Conant, Christopher Thoming, Tamara Stanczak, Zengri Wang, and Michael Smith

Imiquimod 5-Percent Cream Does Not Alter the Natural History of Recurrent Herpes Genitalis: a Phase II, Randomized, Double-Blind, Placebo-Controlled Study
Antimicrob. Agents Chemother. 2002 46: 3243-3248. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pharmacology:

Jian Li, Robert W. Milne, Roger L. Nation, John D. Turnidge, Kingsley Coulthard, and Jason Valentine

Simple Method for Assaying Colistin Methanesulfonate in Plasma and Urine Using High-Performance Liquid Chromatography
Antimicrob. Agents Chemother. 2002 46: 3304-3307. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Eva Maria Kappel, Mehdi Shakibaei, Akintunde Bello, and Ralf Stahlmann

Effects of the Des-F(6)-Quinolone Garenoxacin (BMS-284756), in Comparison to Those of Ciprofloxacin and Ofloxacin, on Joint Cartilage in Immature Rats
Antimicrob. Agents Chemother. 2002 46: 3320-3322. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hiromi Endo, Hideo Yoshida, Yoshiro Kohno, and Tetsuya Suga

Effects of Clarithromycin and Amoxicillin on Gastric Emptying in Rats
Antimicrob. Agents Chemother. 2002 46: 3331-3333. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Letters:

Masaya Takei, Hideyuki Fukuda, Ryuta Kishii, Youko Kadowaki, Yukiko Atobe, and Masaki Hosaka

Contribution of the C-8-Methoxy Group of Gatifloxacin to Inhibition of Type II Topoisomerases of Staphylococcus aureus
Antimicrob. Agents Chemother. 2002 46: 3337-3338. [Full Text] [PDF] [Reprints and Permissions]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.