AAC -- Table of Contents (April 1 2002, 46 [4])

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Contents: April 2002, Volume 46, Issue 4

       Mechanisms of Action

       Mechanisms of Resistance

       Susceptibility

       Antiviral Agents

       Experimental Therapeutics

       Pharmacology

       Biologic Response Modifiers

       Letters

       Recent Approvals

       Errata

Other Issues

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Table of Contents

[Index by Author]

To see an article, click its [Full Text], [Abstract] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

Mechanisms of Action:

Development of a Whole-Cell Assay for Peptidoglycan Biosynthesis Inhibitors
Maria D. F. S. Barbosa, Gaoyun Yang, Jie Fang, Michael G. Kurilla, and David L. Pompliano
Antimicrob. Agents Chemother. April 2002 46: 943-946;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Interaction between Polyamines and Bacterial Outer Membranes as Investigated with Ion-Selective Electrodes
Takashi Katsu, Hideki Nakagawa, and Keiko Yasuda
Antimicrob. Agents Chemother. April 2002 46: 1073-1079;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Oxazolidinone Antibiotics Target the P Site on Escherichia coli Ribosomes
Hiroyuki Aoki, Lizhu Ke, Susan M. Poppe, Toni J. Poel, Elizabeth A. Weaver, Robert C. Gadwood, Richard C. Thomas, Dean L. Shinabarger, and M. Clelia Ganoza
Antimicrob. Agents Chemother. April 2002 46: 1080-1085;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Lack of Catheter Infection by the efg1/efg1 cph1/cph1 Double-Null Mutant, a Candida albicans Strain That Is Defective in Filamentous Growth
Russell E. Lewis, Hsiu-Jung Lo, Issam I. Raad, and Dimitrios P. Kontoyiannis
Antimicrob. Agents Chemother. April 2002 46: 1153-1155;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mechanisms of Resistance:

Candida albicans Sterol C-14 Reductase, Encoded by the ERG24 Gene, as a Potential Antifungal Target Site
N. Jia, B. Arthington-Skaggs, W. Lee, C. A. Pierson, N. D. Lees, J. Eckstein, R. Barbuch, and M. Bard
Antimicrob. Agents Chemother. April 2002 46: 947-957;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Malaria Parasites Giving Rise to Recrudescence In Vitro
Shusuke Nakazawa, Takashi Maoka, Haruki Uemura, Yoshihiro Ito, and Hiroji Kanbara
Antimicrob. Agents Chemother. April 2002 46: 958-965;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Molecular and Biochemical Characterization of Ambler Class A Extended-Spectrum ß-Lactamase CGA-1 from Chryseobacterium gleum
Samuel Bellais, Thierry Naas, and Patrice Nordmann
Antimicrob. Agents Chemother. April 2002 46: 966-970;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Genetic Determinants of Tetracycline Resistance in Vibrio harveyi
Jeanette W. P. Teo, Theresa M. C. Tan, and Chit Laa Poh
Antimicrob. Agents Chemother. April 2002 46: 1038-1045;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Low-Level Resistance to Azoles in Candida albicans Is Associated with Changes in Membrane Lipid Fluidity and Asymmetry
Avmeet Kohli, NFN Smriti, Kasturi Mukhopadhyay, Ashok Rattan, and Rajendra Prasad
Antimicrob. Agents Chemother. April 2002 46: 1046-1052;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

bla_VIM-2 Cassette-Containing Novel Integrons in Metallo-ß-Lactamase-Producing Pseudomonas aeruginosa and Pseudomonas putida Isolates Disseminated in a Korean Hospital
Kyungwon Lee, Jong Back Lim, Jong Hwa Yum, Dongeun Yong, Yunsop Chong, June Myung Kim, and David M. Livermore
Antimicrob. Agents Chemother. April 2002 46: 1053-1058;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

mar Operon Involved in Multidrug Resistance of Enterobacter aerogenes
Renaud Chollet, Claude Bollet, Jacqueline Chevalier, Monique Malléa, Jean-Marie Pagès, and Anne Davin-Regli
Antimicrob. Agents Chemother. April 2002 46: 1093-1097;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

First Description of Klebsiella pneumoniae Harboring CTX-M ß-Lactamases (CTX-M-14 and CTX-M-3) in Taiwan
Wen Liang Yu, Patricia L. Winokur, Diana L. Von Stein, Michael A. Pfaller, Jen Hsien Wang, and Ronald N. Jones
Antimicrob. Agents Chemother. April 2002 46: 1098-1100;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

TEM Derivative-Producing Enterobacter aerogenes Strains: Dissemination of a Prevalent Clone
P. Dumarche, C. De Champs, D. Sirot, C. Chanal, R. Bonnet, and J. Sirot
Antimicrob. Agents Chemother. April 2002 46: 1128-1131;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Cloning and Expression of Class A ß-Lactamase Gene blaA_BPS in Burkholderia pseudomallei
Terence K. M. Cheung, P. L. Ho, Patrick C. Y. Woo, K. Y. Yuen, and P. Y. Chau
Antimicrob. Agents Chemother. April 2002 46: 1132-1135;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Novel Type of Staphylococcal Cassette Chromosome mec Identified in Community-Acquired Methicillin-Resistant Staphylococcus aureus Strains
Xiao Xue Ma, Teruyo Ito, Chuntima Tiensasitorn, Mantana Jamklang, Piriyaporn Chongtrakool, Susan Boyle-Vavra, Robert S. Daum, and Keiichi Hiramatsu
Antimicrob. Agents Chemother. April 2002 46: 1147-1152;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Susceptibility:

In Vitro and In Vivo Activities of a Novel Cephalosporin, BMS-247243, against Methicillin-Resistant and -Susceptible Staphylococci
Joan C. Fung-Tomc, Junius Clark, Beatrice Minassian, Michael Pucci, Yuan-Hwang Tsai, Elizabeth Gradelski, Lucinda Lamb, Ivette Medina, Elizabeth Huczko, Benjamin Kolek, Susan Chaniewski, Cheryl Ferraro, Thomas Washo, and Daniel P. Bonner
Antimicrob. Agents Chemother. April 2002 46: 971-976;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antifungal Activities of Posaconazole, Ravuconazole, and Voriconazole Compared to Those of Itraconazole and Amphotericin B against 239 Clinical Isolates of Aspergillus spp. and Other Filamentous Fungi: Report from SENTRY Antimicrobial Surveillance Program, 2000
M. A. Pfaller, S. A. Messer, R. J. Hollis, and R. N. Jones
Antimicrob. Agents Chemother. April 2002 46: 1032-1037;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Antiplasmodium Effects of Dermaseptin S4 Derivatives
Arie Dagan, Leah Efron, Leonid Gaidukov, Amram Mor, and Hagai Ginsburg
Antimicrob. Agents Chemother. April 2002 46: 1059-1066;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Synergistic Activities of Macrolide Antibiotics against Pseudomonas aeruginosa, Burkholderia cepacia, Stenotrophomonas maltophilia, and Alcaligenes xylosoxidans Isolated from Patients with Cystic Fibrosis
Lisa Saiman, Yunhua Chen, Pablo San Gabriel, and Charles Knirsch
Antimicrob. Agents Chemother. April 2002 46: 1105-1107;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro and In Vivo Activities of a Novel Cephalosporin, BMS-247243, against Organisms other than Staphylococci
Junius Clark, Joan C. Fung-Tomc, Beatrice Minassian, Yuan-Hwang Tsai, Hyekyung Yang, Elizabeth Huczko, Benjamin Kolek, Susan Chaniewski, Cheryl Ferraro, Rebecca Drain, Elizabeth Gradelski, and Daniel P. Bonner
Antimicrob. Agents Chemother. April 2002 46: 1108-1111;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Potent In Vitro Antimalarial Activity of Metacycloprodigiosin Isolated from Streptomyces spectabilis BCC 4785
Masahiko Isaka, Amonlaya Jaturapat, Jarin Kramyu, Morakot Tanticharoen, and Yodhathai Thebtaranonth
Antimicrob. Agents Chemother. April 2002 46: 1112-1113;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Susceptibilities of Mycobacterium marinum to Gatifloxacin, Gemifloxacin, Levofloxacin, Linezolid, Moxifloxacin, Telithromycin, and Quinupristin-Dalfopristin (Synercid) Compared to Its Susceptibilities to Reference Macrolides and Quinolones
Martin Bråbäck, Kristian Riesbeck, and Arne Forsgren
Antimicrob. Agents Chemother. April 2002 46: 1114-1116;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activities of Peptide Deformylase Inhibitors against Gram-Positive Pathogens
R. Wise, J. M. Andrews, and J. Ashby
Antimicrob. Agents Chemother. April 2002 46: 1117-1118;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Activity of BMS-284756, a Novel Des-Fluoro(6) Quinolone, against Staphylococcus aureus, Including Contributions of Mutations to Quinolone Resistance
D. E. Low, M. Muller, C. L. Duncan, B. M. Willey, J. C. de Azavedo, A. McGeer, B. N. Kreiswirth, S. Pong-Porter, and D. J. Bast
Antimicrob. Agents Chemother. April 2002 46: 1119-1121;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Comparative In Vitro Activities of Ertapenem (MK-0826) against 469 Less Frequently Identified Anaerobes Isolated from Human Infections
Ellie J. C. Goldstein, Diane M. Citron, C. Vreni Merriam, Yumi A. Warren, Kerin L. Tyrrell, and Helen Fernandez
Antimicrob. Agents Chemother. April 2002 46: 1136-1140;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activities of a New Des-Fluoroquinolone, BMS 284756, and Seven Other Antimicrobial Agents against 151 Isolates of Eikenella corrodens
Ellie J. C. Goldstein, Diane M. Citron, C. Vreni Merriam, Yumi A. Warren, Kerin L. Tyrrell, and Helen Fernandez
Antimicrob. Agents Chemother. April 2002 46: 1141-1143;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Antifungal Susceptibilities of Trichosporon Species
Niki I. Paphitou, Luis Ostrosky-Zeichner, Victor L. Paetznick, Jose R. Rodriguez, Enuo Chen, and John H. Rex
Antimicrob. Agents Chemother. April 2002 46: 1144-1146;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antiviral Agents:

In Vitro and In Vivo Activities of Anti-Influenza Virus Compound T-705
Y. Furuta, K. Takahashi, Y. Fukuda, M. Kuno, T. Kamiyama, K. Kozaki, N. Nomura, H. Egawa, S. Minami, Y. Watanabe, H. Narita, and K. Shiraki
Antimicrob. Agents Chemother. April 2002 46: 977-981;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Hemofiltrate CC Chemokine 1[9-74] Causes Effective Internalization of CCR5 and Is a Potent Inhibitor of R5-Tropic Human Immunodeficiency Virus Type 1 Strains in Primary T Cells and Macrophages
Jan Münch, Ludger Ständker, Stefan Pöhlmann, Frédéric Baribaud, Armin Papkalla, Olaf Rosorius, Roland Stauber, Gabriele Sass, Nikolaus Heveker, Knut Adermann, Sylvia Escher, Enno Klüver, Robert W. Doms, Wolf-Georg Forssmann, and Frank Kirchhoff
Antimicrob. Agents Chemother. April 2002 46: 982-990;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Enhanced Inhibition of Orthopoxvirus Replication In Vitro by Alkoxyalkyl Esters of Cidofovir and Cyclic Cidofovir
Earl R. Kern, Caroll Hartline, Emma Harden, Kathy Keith, Natalie Rodriguez, James R. Beadle, and Karl Y. Hostetler
Antimicrob. Agents Chemother. April 2002 46: 991-995;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Oral Administration of Cyclopentane Neuraminidase Inhibitors Protects Ferrets against Influenza Virus Infection
Clive Sweet, Kenneth J. Jakeman, Karen Bush, Pamela C. Wagaman, Linda A. Mckown, Anthony J. Streeter, Daksha Desai-Krieger, Pooran Chand, and Yarlagadda S. Babu
Antimicrob. Agents Chemother. April 2002 46: 996-1004;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Kinetic Analysis of Wild-Type and YMDD Mutant Hepatitis B Virus Polymerases and Effects of Deoxyribonucleotide Concentrations on Polymerase Activity
Richard K. Gaillard, Jennifer Barnard, Vincent Lopez, Paula Hodges, Eric Bourne, Lance Johnson, Marchelle I. Allen, Patrick Condreay, Wayne H. Miller, and Lynn D. Condreay
Antimicrob. Agents Chemother. April 2002 46: 1005-1013;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Characterization of A-315675, a Highly Potent Inhibitor of A and B Strain Influenza Virus Neuraminidases and Influenza Virus Replication
Warren M. Kati, Debra Montgomery, Robert Carrick, Larisa Gubareva, Clarence Maring, Keith McDaniel, Kevin Steffy, Akhteruzzaman Molla, Frederick Hayden, Dale Kempf, and William Kohlbrenner
Antimicrob. Agents Chemother. April 2002 46: 1014-1021;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Phenotypic Susceptibilities to Tenofovir in a Large Panel of Clinically Derived Human Immunodeficiency Virus Type 1 Isolates
P. R. Harrigan, M. D. Miller, P. McKenna, Z. L. Brumme, and B. A. Larder
Antimicrob. Agents Chemother. April 2002 46: 1067-1072;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Evolution of Primary Protease Inhibitor Resistance Mutations during Protease Inhibitor Salvage Therapy
Rami Kantor, W. Jeffrey Fessel, Andrew R. Zolopa, Dennis Israelski, Nancy Shulman, Jose G. Montoya, Michael Harbour, Jonathan M. Schapiro, and Robert W. Shafer
Antimicrob. Agents Chemother. April 2002 46: 1086-1092;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Experimental Therapeutics:

In Vitro and In Vivo Activities of Gatifloxacin against Mycobacterium tuberculosis
Enrique J. Alvirez-Freites, Janna L. Carter, and Michael H. Cynamon
Antimicrob. Agents Chemother. April 2002 46: 1022-1025;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Combination of Quinupristin-Dalfopristin (Synercid) and Rifampin Is Highly Synergistic in Experimental Staphylococcus aureus Joint Prosthesis Infection
Azzam Saleh-Mghir, Nourdine Ameur, Claudette Muller-Serieys, Farid Ismael, Françoise Lemaitre, Laurent Massias, Céline Feger, Rémy Bléton, and Anne-Claude Crémieux
Antimicrob. Agents Chemother. April 2002 46: 1122-1124;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pharmacology:

Artemisinin Pharmacokinetics and Efficacy in Uncomplicated-Malaria Patients Treated with Two Different Dosage Regimens
Toufigh Gordi, Dinh Xuan Huong, Trinh Ngoc Hai, Nguyen Thi Nieu, and Michael Ashton
Antimicrob. Agents Chemother. April 2002 46: 1026-1031;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Comparison of Oral Artesunate and Dihydroartemisinin Antimalarial Bioavailabilities in Acute Falciparum Malaria
Paul N. Newton, Michele van Vugt, Paktiya Teja-Isavadharm, Duangsuda Siriyanonda, Maneerat Rasameesoroj, Pramote Teerapong, Ronatrai Ruangveerayuth, Thra Slight, Francois Nosten, Yupin Suputtamongkol, Sornchai Looareesuwan, and Nicholas J. White
Antimicrob. Agents Chemother. April 2002 46: 1125-1127;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Biologic Response Modifiers:

Fourteen-Member Macrolides Suppress Interleukin-8 Production but Do Not Promote Apoptosis of Activated Neutrophils
Yoshiko Tsuchihashi, Kazunori Oishi, Hiroyuki Yoshimine, Shoichi Suzuki, Atsushi Kumatori, Toshiaki Sunazuka, Satoshi Omura, Kouji Matsushima, and Tsuyoshi Nagatake
Antimicrob. Agents Chemother. April 2002 46: 1101-1104;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Letters:

PCR-Restriction Fragment Length Polymorphism Can Also Detect Point Mutation A2142C in the 23S rRNA Gene, Associated with Helicobacter pylori Resistance to Clarithromycin
Armelle Ménard, Adriana Santos, Francis Mégraud, and Mónica Oleastro
Antimicrob. Agents Chemother. April 2002 46: 1156-1157;
[Full Text] [PDF] [Reprints and Permissions]

First Description of a TEM-30 (IRT-2)-Producing Klebsiella oxytoca Isolate
Sophie A. Granier, Jean-Claude Nguyen Van, Marie-Dominique Kitzis, Fred W. Goldstein, Véronique Leflon-Guibout, and Marie-Hélène Nicolas-Chanoine
Antimicrob. Agents Chemother. April 2002 46: 1158-1159;
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Recent Approvals:

New Antimicrobial Agents Approved by the U.S. Food and Drug Administration in 2001 and New Indications for Previously Approved Agents

Antimicrob. Agents Chemother. April 2002 46: 1160
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Errata:

Association of Genetic Mutations in Plasmodium vivax dhfr with Resistance to Sulfadoxine-Pyrimethamine: Geographical and Clinical Correlates
Mallika Imwong, Sasithon Pukrittayakamee, Sornchai Looareesuwan, Geoffrey Pasvol, Jean Poirriez, Nicholas J. White, and Georges Snounou
Antimicrob. Agents Chemother. April 2002 46: 1161
[Full Text] [PDF] [Reprints and Permissions]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.