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Minireviews:

Stephan Harbarth, Sara Cosgrove, and Yehuda Carmeli

Effects of Antibiotics on Nosocomial Epidemiology of Vancomycin-Resistant Enterococci
Antimicrob. Agents Chemother. 2002 46: 1619-1628. [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Resistance:

Mingfu Liu and Stephen Douthwaite

Activity of the Ketolide Telithromycin Is Refractory to Erm Monomethylation of Bacterial rRNA
Antimicrob. Agents Chemother. 2002 46: 1629-1633. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sofia Perea, José L. López-Ribot, Brian L. Wickes, William R. Kirkpatrick, Olga P. Dib, Stefano P. Bachmann, Suzanne M. Keller, Marcos Martinez, and Thomas F. Patterson

Molecular Mechanisms of Fluconazole Resistance in Candida dubliniensis Isolates from Human Immunodeficiency Virus-Infected Patients with Oropharyngeal Candidiasis
Antimicrob. Agents Chemother. 2002 46: 1695-1703. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Theodore C. White, Scott Holleman, Francis Dy, Laurence F. Mirels, and David A. Stevens

Resistance Mechanisms in Clinical Isolates of Candida albicans
Antimicrob. Agents Chemother. 2002 46: 1704-1713. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

David Boyd, Axel Cloeckaert, Elisabeth Chaslus-Dancla, and Michael R. Mulvey

Characterization of Variant Salmonella Genomic Island 1 Multidrug Resistance Regions from Serovars Typhimurium DT104 and Agona
Antimicrob. Agents Chemother. 2002 46: 1714-1722. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Yoshikuni Onodera, Jun Okuda, Mayumi Tanaka, and Kenichi Sato

Inhibitory Activities of Quinolones against DNA Gyrase and Topoisomerase IV of Enterococcus faecalis
Antimicrob. Agents Chemother. 2002 46: 1800-1804. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jonathan Heddle and Anthony Maxwell

Quinolone-Binding Pocket of DNA Gyrase: Role of GyrB
Antimicrob. Agents Chemother. 2002 46: 1805-1815. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Stefania Cresti, Maria Lattanzi, Alessandra Zanchi, Francesca Montagnani, Simona Pollini, Carla Cellesi, and Gian Maria Rossolini

Resistance Determinants and Clonal Diversity in Group A Streptococci Collected during a Period of Increasing Macrolide Resistance
Antimicrob. Agents Chemother. 2002 46: 1816-1822. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jean-Denis Docquier, Fabrizio Pantanella, Francesco Giuliani, Maria Cristina Thaller, Gianfranco Amicosante, Moreno Galleni, Jean-Marie Frère, Karen Bush, and Gian Maria Rossolini

CAU-1, a Subclass B3 Metallo-ß-Lactamase of Low Substrate Affinity Encoded by an Ortholog Present in the Caulobacter crescentus Chromosome
Antimicrob. Agents Chemother. 2002 46: 1823-1830. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kavindra V. Singh, George M. Weinstock, and Barbara E. Murray

An Enterococcus faecalis ABC Homologue (Lsa) Is Required for the Resistance of This Species to Clindamycin and Quinupristin-Dalfopristin
Antimicrob. Agents Chemother. 2002 46: 1845-1850. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sandrine Vessillier, Jean-Denis Docquier, Sandrine Rival, Jean-Marie Frere, Moreno Galleni, Gianfranco Amicosante, Gian Maria Rossolini, and Nicola Franceschini

Overproduction and Biochemical Characterization of the Chryseobacterium meningosepticum BlaB Metallo-ß-Lactamase
Antimicrob. Agents Chemother. 2002 46: 1921-1927. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Virve I. Enne, Anna King, David M. Livermore, and Lucinda M. C. Hall

Sulfonamide Resistance in Haemophilus influenzae Mediated by Acquisition of sul2 or a Short Insertion in Chromosomal folP
Antimicrob. Agents Chemother. 2002 46: 1934-1939. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sergei B. Vakulenko, Dasantila Golemi, Bruce Geryk, Maxim Suvorov, James R. Knox, Shahriar Mobashery, and Stephen A. Lerner

Mutational Replacement of Leu-293 in the Class C Enterobacter cloacae P99 ß-Lactamase Confers Increased MIC of Cefepime
Antimicrob. Agents Chemother. 2002 46: 1966-1970. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

D. A. Boyd, T. Cabral, P. Van Caeseele, J. Wylie, and M. R. Mulvey

Molecular Characterization of the vanE Gene Cluster in Vancomycin-Resistant Enterococcus faecalis N00-410 Isolated in Canada
Antimicrob. Agents Chemother. 2002 46: 1977-1979. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

L. Ma, Yoshikazu Ishii, Feng-Yee Chang, Keizo Yamaguchi, Monto Ho, and L. K. Siu

CTX-M-14, a Plasmid-Mediated CTX-M Type Extended-Spectrum ß-Lactamase Isolated from Escherichia coli
Antimicrob. Agents Chemother. 2002 46: 1985-1988. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

J. Kamile Rasheed, Gregory J. Anderson, Anne Marie Queenan, James W. Biddle, Antonio Oliver, George A. Jacoby, Karen Bush, and Fred C. Tenover

TEM-71, a Novel Plasmid-Encoded, Extended-Spectrum ß-Lactamase Produced by a Clinical Isolate of Klebsiella pneumoniae
Antimicrob. Agents Chemother. 2002 46: 2000-2003. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

R. Bonnet, H. Marchandin, C. Chanal, D. Sirot, R. Labia, C. De Champs, E. Jumas-Bilak, and J. Sirot

Chromosome-Encoded Class D ß-Lactamase OXA-23 in Proteus mirabilis
Antimicrob. Agents Chemother. 2002 46: 2004-2006. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Shizuko Iyobe, Haruko Kusadokoro, Ayako Takahashi, Sachie Yomoda, Toyoji Okubo, Akio Nakamura, and Koji O'Hara

Detection of a Variant Metallo-ß-Lactamase, IMP-10, from Two Unrelated Strains of Pseudomonas aeruginosa and an Alcaligenes xylosoxidans Strain
Antimicrob. Agents Chemother. 2002 46: 2014-2016. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Chi-Tai Fang, Haur-Chuan Chen, Yi-Ping Chuang, Shan-Chwen Chang, and Jin-Town Wang

Cloning of a Cation Efflux Pump Gene Associated with Chlorhexidine Resistance in Klebsiella pneumoniae
Antimicrob. Agents Chemother. 2002 46: 2024-2028. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Action:

Antonella Lupetti, Akke Paulusma-Annema, Sonia Senesi, Mario Campa, Jaap T. van Dissel, and Peter H. Nibbering

Internal Thiols and Reactive Oxygen Species in Candidacidal Activity Exerted by an N-Terminal Peptide of Human Lactoferrin
Antimicrob. Agents Chemother. 2002 46: 1634-1639. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Chirag B. Shah, Marc W. Mittelman, J. W. Costerton, Stephen Parenteau, Michael Pelak, Richard Arsenault, and Leonard A. Mermel

Antimicrobial Activity of a Novel Catheter Lock Solution
Antimicrob. Agents Chemother. 2002 46: 1674-1679. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Antonio Javier Martín-Galiano, Begoña Gorgojo, Calvin M. Kunin, and Adela G. de la Campa

Mefloquine and New Related Compounds Target the F₀ Complex of the F₀F₁ H⁺-ATPase of Streptococcus pneumoniae
Antimicrob. Agents Chemother. 2002 46: 1680-1687. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Letizia Angiolella, Mia M. Micocci, Simona D'Alessio, Antonietta Girolamo, Bruno Maras, and Antonio Cassone

Identification of Major Glucan-Associated Cell Wall Proteins of Candida albicans and Their Role in Fluconazole Resistance
Antimicrob. Agents Chemother. 2002 46: 1688-1694. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Shabana I. Khan, Alison C. Nimrod, Mohammed Mehrpooya, John L. Nitiss, Larry A. Walker, and Alice M. Clark

Antifungal Activity of Eupolauridine and Its Action on DNA Topoisomerases
Antimicrob. Agents Chemother. 2002 46: 1785-1792. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

John M. Clements, Fanny Coignard, Ian Johnson, Stephen Chandler, Shilpa Palan, Andrew Waller, Jac Wijkmans, and Michael G. Hunter

Antibacterial Activities and Characterization of Novel Inhibitors of LpxC
Antimicrob. Agents Chemother. 2002 46: 1793-1799. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Christine F. Carson, Brian J. Mee, and Thomas V. Riley

Mechanism of Action of Melaleuca alternifolia (Tea Tree) Oil on Staphylococcus aureus Determined by Time-Kill, Lysis, Leakage, and Salt Tolerance Assays and Electron Microscopy
Antimicrob. Agents Chemother. 2002 46: 1914-1920. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Markus Nagl, Andreas Gruber, Anita Fuchs, Claudia P. Lell, Eva-Maria Lemberger, Margarete Borg-von Zepelin, and Reinhard Würzner

Impact of N-Chlorotaurine on Viability and Production of Secreted Aspartyl Proteinases of Candida spp.
Antimicrob. Agents Chemother. 2002 46: 1996-1999. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Xin Zhao, Cory Q. Wenzel, and Joseph S. Lam

Nonradiolabeling Assay for WaaP, an Essential Sugar Kinase Involved in Biosynthesis of Core Lipopolysaccharide of Pseudomonas aeruginosa
Antimicrob. Agents Chemother. 2002 46: 2035-2037. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Shruti M. Phadke, Vanja Lazarevic, Caroline C. Bahr, Kazi Islam, Donna Beer Stolz, Simon Watkins, Sarah B. Tencza, Hans J. Vogel, Ronald C. Montelaro, and Timothy A. Mietzner

Lentivirus Lytic Peptide 1 Perturbs both Outer and Inner Membranes of Serratia marcescens
Antimicrob. Agents Chemother. 2002 46: 2041-2045. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Antiviral Agents:

Robert W. King, Ronald M. Klabe, Carol D. Reid, and Susan K. Erickson-Viitanen

Potency of Nonnucleoside Reverse Transcriptase Inhibitors (NNRTIs) Used in Combination with Other Human Immunodeficiency Virus NNRTIs, NRTIs, or Protease Inhibitors
Antimicrob. Agents Chemother. 2002 46: 1640-1646. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

B. Hernandez-Santiago, L. Placidi, E. Cretton-Scott, A. Faraj, E. G. Bridges, M. L. Bryant, J. Rodriguez-Orengo, J. L. Imbach, G. Gosselin, C. Pierra, D. Dukhan, and J. P. Sommadossi

Pharmacology of ß-L-Thymidine and ß-L-2'-Deoxycytidine in HepG2 Cells and Primary Human Hepatocytes: Relevance to Chemotherapeutic Efficacy against Hepatitis B Virus
Antimicrob. Agents Chemother. 2002 46: 1728-1733. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

R. G. Gish, N. W. Y. Leung, T. L. Wright, Huy Trinh, W. Lang, H. A. Kessler, L. Fang, L. H. Wang, J. Delehanty, A. Rigney, E. Mondou, A. Snow, and F. Rousseau

Dose Range Study of Pharmacokinetics, Safety, and Preliminary Antiviral Activity of Emtricitabine in Adults with Hepatitis B Virus Infection
Antimicrob. Agents Chemother. 2002 46: 1734-1740. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ulrich A. K. Betz, Rüdiger Fischer, Gerald Kleymann, Martin Hendrix, and Helga Rübsamen-Waigmann

Potent In Vivo Antiviral Activity of the Herpes Simplex Virus Primase-Helicase Inhibitor BAY 57-1293
Antimicrob. Agents Chemother. 2002 46: 1766-1772. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jane Alcorn and Patrick J. McNamara

Acyclovir, Ganciclovir, and Zidovudine Transfer into Rat Milk
Antimicrob. Agents Chemother. 2002 46: 1831-1836. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Dimitrios Motakis and Michael A. Parniak

A Tight-Binding Mode of Inhibition Is Essential for Anti-Human Immunodeficiency Virus Type 1 Virucidal Activity of Nonnucleoside Reverse Transcriptase Inhibitors
Antimicrob. Agents Chemother. 2002 46: 1851-1856. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Xiping Wei, Julie M. Decker, Hongmei Liu, Zee Zhang, Ramin B. Arani, J. Michael Kilby, Michael S. Saag, Xiaoyun Wu, George M. Shaw, and John C. Kappes

Emergence of Resistant Human Immunodeficiency Virus Type 1 in Patients Receiving Fusion Inhibitor (T-20) Monotherapy
Antimicrob. Agents Chemother. 2002 46: 1896-1905. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Véronique Joly, Philippe Flandre, Vincent Meiffredy, Françoise Brun-Vezinet, Jean-Albert Gastaut, Cécile Goujard, Gérard Remy, Diane Descamps, Annick Ruffault, Agnès Certain, Jean-Pierre Aboulker, and Patrick Yeni

Efficacy of Zidovudine Compared to Stavudine, Both in Combination with Lamivudine and Indinavir, in Human Immunodeficiency Virus-Infected Nucleoside-Experienced Patients with No Prior Exposure to Lamivudine, Stavudine, or Protease Inhibitors (Novavir Trial)
Antimicrob. Agents Chemother. 2002 46: 1906-1913. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jean Servais, Christine Lambert, Jean-Marc Plesséria, Elodie Fontaine, Isabelle Robert, Vic Arendt, Thérèse Staub, Robert Hemmer, François Schneider, and Jean-Claude Schmit

Longitudinal Use of a Line Probe Assay for Human Immunodeficiency Virus Type 1 Protease Predicts Phenotypic Resistance and Clinical Progression in Patients Failing Highly Active Antiretroviral Therapy
Antimicrob. Agents Chemother. 2002 46: 1928-1933. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Charles Oo, Joanne Barrett, Albert Dorr, Baolian Liu, and Penelope Ward

Lack of Pharmacokinetic Interaction between the Oral Anti-Influenza Prodrug Oseltamivir and Aspirin
Antimicrob. Agents Chemother. 2002 46: 1993-1995. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Susceptibility:

T. Peláez, L. Alcalá, R. Alonso, M. Rodríguez-Créixems, J. M. García-Lechuz, and E. Bouza

Reassessment of Clostridium difficile Susceptibility to Metronidazole and Vancomycin
Antimicrob. Agents Chemother. 2002 46: 1647-1650. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mark E. Jones, Ian A. Critchley, James A. Karlowsky, Renée S. Blosser-Middleton, Franz-Josef Schmitz, Clyde Thornsberry, and Daniel F. Sahm

In Vitro Activities of Novel Nonfluorinated Quinolones PGE 9262932 and PGE 9509924 against Clinical Isolates of Staphylococcus aureus and Streptococcus pneumoniae with Defined Mutations in DNA Gyrase and Topoisomerase IV
Antimicrob. Agents Chemother. 2002 46: 1651-1657. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Harald Noedl, Walther H. Wernsdorfer, Robert Scott Miller, and Chansuda Wongsrichanalai

Histidine-Rich Protein II: a Novel Approach to Malaria Drug Sensitivity Testing
Antimicrob. Agents Chemother. 2002 46: 1658-1664. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

M. A. Pfaller, S. A. Messer, R. J. Hollis, R. N. Jones, and D. J. Diekema

In Vitro Activities of Ravuconazole and Voriconazole Compared with Those of Four Approved Systemic Antifungal Agents against 6,970 Clinical Isolates of Candida spp.
Antimicrob. Agents Chemother. 2002 46: 1723-1727. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

D. M. Kuhn, T. George, J. Chandra, P. K. Mukherjee, and M. A. Ghannoum

Antifungal Susceptibility of Candida Biofilms: Unique Efficacy of Amphotericin B Lipid Formulations and Echinocandins
Antimicrob. Agents Chemother. 2002 46: 1773-1780. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

A. L. Barry, M. A. Pfaller, R. P. Rennie, P. C. Fuchs, and S. D. Brown

Precision and Accuracy of Fluconazole Susceptibility Testing by Broth Microdilution, Etest, and Disk Diffusion Methods
Antimicrob. Agents Chemother. 2002 46: 1781-1784. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Maria Bellantone, Huw D. Williams, and Larry L. Hench

Broad-Spectrum Bactericidal Activity of Ag₂O-Doped Bioactive Glass
Antimicrob. Agents Chemother. 2002 46: 1940-1945. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Roxana G. Vitale, Johan W. Mouton, Javier Afeltra, Jacques F. G. M. Meis, and Paul E. Verweij

Method for Measuring Postantifungal Effect in Aspergillus Species
Antimicrob. Agents Chemother. 2002 46: 1960-1965. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Emmanuel Roilides, Caron A. Lyman, Joanna Filioti, Onome Akpogheneta, Tin Sein, Cristina Gil Lamaignere, Ruta Petraitiene, and Thomas J. Walsh

Amphotericin B Formulations Exert Additive Antifungal Activity in Combination with Pulmonary Alveolar Macrophages and Polymorphonuclear Leukocytes against Aspergillus fumigatus
Antimicrob. Agents Chemother. 2002 46: 1974-1976. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

David A. Cacchillo and John D. Walters

Effect of Ciprofloxacin on Killing of Actinobacillus actinomycetemcomitans by Polymorphonuclear Leukocytes
Antimicrob. Agents Chemother. 2002 46: 1980-1984. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

James A. Karlowsky, Laurie J. Kelly, Ian A. Critchley, Mark E. Jones, Clyde Thornsberry, and Daniel F. Sahm

Determining Linezolid’s Baseline In Vitro Activity in Canada Using Gram-Positive Clinical Isolates Collected prior to Its National Release
Antimicrob. Agents Chemother. 2002 46: 1989-1992. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Simon Kilvington, Reanne Hughes, James Byas, and John Dart

Activities of Therapeutic Agents and Myristamidopropyl Dimethylamine against Acanthamoeba Isolates
Antimicrob. Agents Chemother. 2002 46: 2007-2009. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Andrea Rotheneder, Gernot Fritsche, Lothar Heinisch, Ute Möllmann, Susanne Heggemann, Clara Larcher, and Günter Weiss

Effects of Synthetic Siderophores on Proliferation of Plasmodium falciparum in Infected Human Erythrocytes
Antimicrob. Agents Chemother. 2002 46: 2010-2013. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Nandini Kiri, Gordon Archer, and Michael W. Climo

Combinations of Lysostaphin with ß-Lactams Are Synergistic against Oxacillin-Resistant Staphylococcus epidermidis
Antimicrob. Agents Chemother. 2002 46: 2017-2020. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Paula Prazeres Magalhães, Dulciene Maria de Magalhães Queiroz, Daniela Vale Campos Barbosa, Gifone Aguiar Rocha, Edilberto Nogueira Mendes, Adriana Santos, Paulo Renato Valle Corrêa, Andreia Maria Camargos Rocha, Lúcia Martins Teixeira, and Celso Affonso de Oliveira

Helicobacter pylori Primary Resistance to Metronidazole and Clarithromycin in Brazil
Antimicrob. Agents Chemother. 2002 46: 2021-2023. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Javier Afeltra, Jacques F. G. M. Meis, Roxana G. Vitale, Johan W. Mouton, and Paul E. Verweij

In Vitro Activities of Pentamidine, Pyrimethamine, Trimethoprim, and Sulfonamides against Aspergillus Species
Antimicrob. Agents Chemother. 2002 46: 2029-2031. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Joseph Nkemgu-Njinkeng, Vera Rosenkranz, Michael Wink, and Dietmar Steverding

Antitrypanosomal Activities of Proteasome Inhibitors
Antimicrob. Agents Chemother. 2002 46: 2038-2040. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Maud Santillana-Hayat, Claudine Sarfati, Sandra Fournier, Françoise Chau, Raphaël Porcher, Jean-Michel Molina, and Francis Derouin

Effects of Chemical and Physical Agents on Viability and Infectivity of Encephalitozoon intestinalis Determined by Cell Culture and Flow Cytometry
Antimicrob. Agents Chemother. 2002 46: 2049-2051. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Experimental Therapeutics:

D. Andes and W. A. Craig

Pharmacodynamics of the New Fluoroquinolone Gatifloxacin in Murine Thigh and Lung Infection Models
Antimicrob. Agents Chemother. 2002 46: 1665-1670. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Biliana Lesic, Jeannine Foulon, and Elisabeth Carniel

Comparison of the Effects of Deferiprone versus Deferoxamine on Growth and Virulence of Yersinia enterocolitica
Antimicrob. Agents Chemother. 2002 46: 1741-1745. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Masahiro Takahata, Hiroshi Yamada, Teiichi Morita, Shinichi Furubou, Shinzaburo Minami, Yozo Todo, Yasuo Watanabe, and Hirokazu Narita

Evaluation of T-3811ME (BMS-284756), a New Des-F(6)-Quinolone, for Treatment of Meningitis Caused by Penicillin-Resistant Streptococcus pneumoniae in Rabbits
Antimicrob. Agents Chemother. 2002 46: 1760-1765. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Lars Steinstraesser, Brian F. Tack, Alan J. Waring, Teresa Hong, Lee M. Boo, Ming-Hui Fan, Daniel I. Remick, Grace L. Su, Robert I. Lehrer, and Stewart C. Wang

Activity of Novispirin G10 against Pseudomonas aeruginosa In Vitro and in Infected Burns
Antimicrob. Agents Chemother. 2002 46: 1837-1844. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Vidmantas Petraitis, Ruta Petraitiene, Andreas H. Groll, Kristin Roussillon, Melissa Hemmings, Caron A. Lyman, Tin Sein, John Bacher, Ihor Bekersky, and Thomas J. Walsh

Comparative Antifungal Activities and Plasma Pharmacokinetics of Micafungin (FK463) against Disseminated Candidiasis and Invasive Pulmonary Aspergillosis in Persistently Neutropenic Rabbits
Antimicrob. Agents Chemother. 2002 46: 1857-1869. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Tetsuyuki Yoshimatsu, Eric Nuermberger, Sandeep Tyagi, Richard Chaisson, William Bishai, and Jacques Grosset

Bactericidal Activity of Increasing Daily and Weekly Doses of Moxifloxacin in Murine Tuberculosis
Antimicrob. Agents Chemother. 2002 46: 1875-1879. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Liana Tsenova, Bande Mangaliso, George Muller, Yong Chen, Victoria H. Freedman, David Stirling, and Gilla Kaplan

Use of IMiD3, a Thalidomide Analog, as an Adjunct to Therapy for Experimental Tuberculous Meningitis
Antimicrob. Agents Chemother. 2002 46: 1887-1895. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

A. Montero, J. Ariza, X. Corbella, A. Doménech, C. Cabellos, J. Ayats, F. Tubau, C. Ardanuy, and F. Gudiol

Efficacy of Colistin versus ß-Lactams, Aminoglycosides, and Rifampin as Monotherapy in a Mouse Model of Pneumonia Caused by Multiresistant Acinetobacter baumannii
Antimicrob. Agents Chemother. 2002 46: 1946-1952. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Eric Dannaoui, Johan W. Mouton, Jacques F. G. M. Meis, and Paul E. Verweij

Efficacy of Antifungal Therapy in a Nonneutropenic Murine Model of Zygomycosis
Antimicrob. Agents Chemother. 2002 46: 1953-1959. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Todd A. Parker, Kenneth O. Willeford, Suzanne Parker, and Karyl Buddington

Reducing Mortality in Salmonella enterica Serovar Typhimurium-Infected Mice with a Tripeptidic Serum Fraction
Antimicrob. Agents Chemother. 2002 46: 1971-1973. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Samuel Bellais, Olivier Mimoz, Sophie Léotard, Anne Jacolot, Olivier Petitjean, and Patrice Nordmann

Efficacy of ß-Lactams for Treating Experimentally Induced Pneumonia Due to a Carbapenem-Hydrolyzing Metallo-ß-Lactamase-Producing Strain of Pseudomonas aeruginosa
Antimicrob. Agents Chemother. 2002 46: 2032-2034. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Inga Odenholt, Elisabeth Löwdin, Ingegerd Gustafsson, and Otto Cars

Pharmacodynamics of Moxifloxacin against Streptococcus pyogenes in an In Vitro Kinetic Model
Antimicrob. Agents Chemother. 2002 46: 2046-2048. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Clinical Therapeutics:

Michael Dan, Francesca Poch, and Bracha Sheinberg

High Prevalence of High-Level Ciprofloxacin Resistance in Neisseria gonorrhoeae in Tel Aviv, Israel: Correlation with Response to Therapy
Antimicrob. Agents Chemother. 2002 46: 1671-1673. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

R. Finch, D. Schürmann, O. Collins, R. Kubin, J. McGivern, H. Bobbaers, J. L. Izquierdo, P. Nikolaides, F. Ogundare, R. Raz, P. Zuck, and G. Hoeffken

Randomized Controlled Trial of Sequential Intravenous (i.v.) and Oral Moxifloxacin Compared with Sequential i.v. and Oral Co-Amoxiclav with or without Clarithromycin in Patients with Community-Acquired Pneumonia Requiring Initial Parenteral Treatment
Antimicrob. Agents Chemother. 2002 46: 1746-1754. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

T. G. Evans, D. I. Bernstein, G. W. Raborn, J. Harmenberg, J. Kowalski, and S. L. Spruance

Double-Blind, Randomized, Placebo-Controlled Study of Topical 5% Acyclovir-1% Hydrocortisone Cream (ME-609) for Treatment of UV Radiation-Induced Herpes Labialis
Antimicrob. Agents Chemother. 2002 46: 1870-1874. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pharmacology:

Edith Lozo, Kai Riecke, Rudolf Schwabe, Jürgen Vormann, and Ralf Stahlmann

Synergistic Effect of Ofloxacin and Magnesium Deficiency on Joint Cartilage in Immature Rats
Antimicrob. Agents Chemother. 2002 46: 1755-1759. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Chemistry; Biosynthesis:

David J. Payne, Juan Antonio Hueso-Rodríguez, Helen Boyd, Néstor O. Concha, Cheryl A. Janson, Martin Gilpin, John H. Bateson, Christy Cheever, Nancy L. Niconovich, Stewart Pearson, Stephen Rittenhouse, David Tew, Emilio Díez, Paloma Pérez, Jesus de la Fuente, Michael Rees, and Alfonso Rivera-Sagredo

Identification of a Series of Tricyclic Natural Products as Potent Broad-Spectrum Inhibitors of Metallo-ß-Lactamases
Antimicrob. Agents Chemother. 2002 46: 1880-1886. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Letters:

Le Van Phung, Haruko Ryo, and Taisei Nomura

Specific gyrA Mutation at Codon 83 in Nalidixic Acid-Resistant Salmonella enterica Serovar Typhi Strains Isolated from Vietnamese Patients
Antimicrob. Agents Chemother. 2002 46: 2052-2053. [Full Text] [PDF] [Reprints and Permissions]  

Kayode K. Ojo, Corinna Kehrenberg, Stefan Schwarz, and H. Akin Odelola

Identification of a Complete dfrA14 Gene Cassette Integrated at a Secondary Site in a Resistance Plasmid of Uropathogenic Escherichia coli from Nigeria
Antimicrob. Agents Chemother. 2002 46: 2054-2055. [Full Text] [PDF] [Reprints and Permissions]  

Sophie A. Granier, Véronique Leflon-Guibout, Marie-Hélène Nicolas-Chanoine, Karen Bush, and Fred W. Goldstein

The Extended-Spectrum K1 ß-Lactamase from Klebsiella oxytoca SC 10,436 Is a Member of the bla_OXY-2 Family of Chromosomal Klebsiella Enzymes
Antimicrob. Agents Chemother. 2002 46: 2056-2057. [Full Text] [PDF] [Reprints and Permissions]  

Fabio Tosini, Ruth M. Hall, H. W. Stokes, and Sally R. Partridge

Integration of Integrons in res Sites
Antimicrob. Agents Chemother. 2002 46: 2058. [Full Text] [PDF] [Reprints and Permissions]  

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