AAC -- Table of Contents (June 1 2002, 46 [6])

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Contents: June 2002, Volume 46, Issue 6

       Minireviews

       Mechanisms of Resistance

       Mechanisms of Action

       Antiviral Agents

       Susceptibility

       Experimental Therapeutics

       Clinical Therapeutics

       Pharmacology

       Chemistry; Biosynthesis

       Letters

Other Issues

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Table of Contents

[Index by Author]

To see an article, click its [Full Text], [Abstract] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

Minireviews:

Effects of Antibiotics on Nosocomial Epidemiology of Vancomycin-Resistant Enterococci
Stephan Harbarth, Sara Cosgrove, and Yehuda Carmeli
Antimicrob. Agents Chemother. June 2002 46: 1619-1628;
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Mechanisms of Resistance:

Activity of the Ketolide Telithromycin Is Refractory to Erm Monomethylation of Bacterial rRNA
Mingfu Liu and Stephen Douthwaite
Antimicrob. Agents Chemother. June 2002 46: 1629-1633;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Molecular Mechanisms of Fluconazole Resistance in Candida dubliniensis Isolates from Human Immunodeficiency Virus-Infected Patients with Oropharyngeal Candidiasis
Sofia Perea, José L. López-Ribot, Brian L. Wickes, William R. Kirkpatrick, Olga P. Dib, Stefano P. Bachmann, Suzanne M. Keller, Marcos Martinez, and Thomas F. Patterson
Antimicrob. Agents Chemother. June 2002 46: 1695-1703;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Resistance Mechanisms in Clinical Isolates of Candida albicans
Theodore C. White, Scott Holleman, Francis Dy, Laurence F. Mirels, and David A. Stevens
Antimicrob. Agents Chemother. June 2002 46: 1704-1713;
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Characterization of Variant Salmonella Genomic Island 1 Multidrug Resistance Regions from Serovars Typhimurium DT104 and Agona
David Boyd, Axel Cloeckaert, Elisabeth Chaslus-Dancla, and Michael R. Mulvey
Antimicrob. Agents Chemother. June 2002 46: 1714-1722;
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Inhibitory Activities of Quinolones against DNA Gyrase and Topoisomerase IV of Enterococcus faecalis
Yoshikuni Onodera, Jun Okuda, Mayumi Tanaka, and Kenichi Sato
Antimicrob. Agents Chemother. June 2002 46: 1800-1804;
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Quinolone-Binding Pocket of DNA Gyrase: Role of GyrB
Jonathan Heddle and Anthony Maxwell
Antimicrob. Agents Chemother. June 2002 46: 1805-1815;
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Resistance Determinants and Clonal Diversity in Group A Streptococci Collected during a Period of Increasing Macrolide Resistance
Stefania Cresti, Maria Lattanzi, Alessandra Zanchi, Francesca Montagnani, Simona Pollini, Carla Cellesi, and Gian Maria Rossolini
Antimicrob. Agents Chemother. June 2002 46: 1816-1822;
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CAU-1, a Subclass B3 Metallo-ß-Lactamase of Low Substrate Affinity Encoded by an Ortholog Present in the Caulobacter crescentus Chromosome
Jean-Denis Docquier, Fabrizio Pantanella, Francesco Giuliani, Maria Cristina Thaller, Gianfranco Amicosante, Moreno Galleni, Jean-Marie Frère, Karen Bush, and Gian Maria Rossolini
Antimicrob. Agents Chemother. June 2002 46: 1823-1830;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

An Enterococcus faecalis ABC Homologue (Lsa) Is Required for the Resistance of This Species to Clindamycin and Quinupristin-Dalfopristin
Kavindra V. Singh, George M. Weinstock, and Barbara E. Murray
Antimicrob. Agents Chemother. June 2002 46: 1845-1850;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Overproduction and Biochemical Characterization of the Chryseobacterium meningosepticum BlaB Metallo-ß-Lactamase
Sandrine Vessillier, Jean-Denis Docquier, Sandrine Rival, Jean-Marie Frere, Moreno Galleni, Gianfranco Amicosante, Gian Maria Rossolini, and Nicola Franceschini
Antimicrob. Agents Chemother. June 2002 46: 1921-1927;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Sulfonamide Resistance in Haemophilus influenzae Mediated by Acquisition of sul2 or a Short Insertion in Chromosomal folP
Virve I. Enne, Anna King, David M. Livermore, and Lucinda M. C. Hall
Antimicrob. Agents Chemother. June 2002 46: 1934-1939;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mutational Replacement of Leu-293 in the Class C Enterobacter cloacae P99 ß-Lactamase Confers Increased MIC of Cefepime
Sergei B. Vakulenko, Dasantila Golemi, Bruce Geryk, Maxim Suvorov, James R. Knox, Shahriar Mobashery, and Stephen A. Lerner
Antimicrob. Agents Chemother. June 2002 46: 1966-1970;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Molecular Characterization of the vanE Gene Cluster in Vancomycin-Resistant Enterococcus faecalis N00-410 Isolated in Canada
D. A. Boyd, T. Cabral, P. Van Caeseele, J. Wylie, and M. R. Mulvey
Antimicrob. Agents Chemother. June 2002 46: 1977-1979;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

CTX-M-14, a Plasmid-Mediated CTX-M Type Extended-Spectrum ß-Lactamase Isolated from Escherichia coli
L. Ma, Yoshikazu Ishii, Feng-Yee Chang, Keizo Yamaguchi, Monto Ho, and L. K. Siu
Antimicrob. Agents Chemother. June 2002 46: 1985-1988;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

TEM-71, a Novel Plasmid-Encoded, Extended-Spectrum ß-Lactamase Produced by a Clinical Isolate of Klebsiella pneumoniae
J. Kamile Rasheed, Gregory J. Anderson, Anne Marie Queenan, James W. Biddle, Antonio Oliver, George A. Jacoby, Karen Bush, and Fred C. Tenover
Antimicrob. Agents Chemother. June 2002 46: 2000-2003;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Chromosome-Encoded Class D ß-Lactamase OXA-23 in Proteus mirabilis
R. Bonnet, H. Marchandin, C. Chanal, D. Sirot, R. Labia, C. De Champs, E. Jumas-Bilak, and J. Sirot
Antimicrob. Agents Chemother. June 2002 46: 2004-2006;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Detection of a Variant Metallo-ß-Lactamase, IMP-10, from Two Unrelated Strains of Pseudomonas aeruginosa and an Alcaligenes xylosoxidans Strain
Shizuko Iyobe, Haruko Kusadokoro, Ayako Takahashi, Sachie Yomoda, Toyoji Okubo, Akio Nakamura, and Koji O'Hara
Antimicrob. Agents Chemother. June 2002 46: 2014-2016;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Cloning of a Cation Efflux Pump Gene Associated with Chlorhexidine Resistance in Klebsiella pneumoniae
Chi-Tai Fang, Haur-Chuan Chen, Yi-Ping Chuang, Shan-Chwen Chang, and Jin-Town Wang
Antimicrob. Agents Chemother. June 2002 46: 2024-2028;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mechanisms of Action:

Internal Thiols and Reactive Oxygen Species in Candidacidal Activity Exerted by an N-Terminal Peptide of Human Lactoferrin
Antonella Lupetti, Akke Paulusma-Annema, Sonia Senesi, Mario Campa, Jaap T. van Dissel, and Peter H. Nibbering
Antimicrob. Agents Chemother. June 2002 46: 1634-1639;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antimicrobial Activity of a Novel Catheter Lock Solution
Chirag B. Shah, Marc W. Mittelman, J. W. Costerton, Stephen Parenteau, Michael Pelak, Richard Arsenault, and Leonard A. Mermel
Antimicrob. Agents Chemother. June 2002 46: 1674-1679;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mefloquine and New Related Compounds Target the F₀ Complex of the F₀F₁ H⁺-ATPase of Streptococcus pneumoniae
Antonio Javier Martín-Galiano, Begoña Gorgojo, Calvin M. Kunin, and Adela G. de la Campa
Antimicrob. Agents Chemother. June 2002 46: 1680-1687;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Identification of Major Glucan-Associated Cell Wall Proteins of Candida albicans and Their Role in Fluconazole Resistance
Letizia Angiolella, Mia M. Micocci, Simona D'Alessio, Antonietta Girolamo, Bruno Maras, and Antonio Cassone
Antimicrob. Agents Chemother. June 2002 46: 1688-1694;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antifungal Activity of Eupolauridine and Its Action on DNA Topoisomerases
Shabana I. Khan, Alison C. Nimrod, Mohammed Mehrpooya, John L. Nitiss, Larry A. Walker, and Alice M. Clark
Antimicrob. Agents Chemother. June 2002 46: 1785-1792;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antibacterial Activities and Characterization of Novel Inhibitors of LpxC
John M. Clements, Fanny Coignard, Ian Johnson, Stephen Chandler, Shilpa Palan, Andrew Waller, Jac Wijkmans, and Michael G. Hunter
Antimicrob. Agents Chemother. June 2002 46: 1793-1799;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mechanism of Action of Melaleuca alternifolia (Tea Tree) Oil on Staphylococcus aureus Determined by Time-Kill, Lysis, Leakage, and Salt Tolerance Assays and Electron Microscopy
Christine F. Carson, Brian J. Mee, and Thomas V. Riley
Antimicrob. Agents Chemother. June 2002 46: 1914-1920;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Impact of N-Chlorotaurine on Viability and Production of Secreted Aspartyl Proteinases of Candida spp.
Markus Nagl, Andreas Gruber, Anita Fuchs, Claudia P. Lell, Eva-Maria Lemberger, Margarete Borg-von Zepelin, and Reinhard Würzner
Antimicrob. Agents Chemother. June 2002 46: 1996-1999;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Nonradiolabeling Assay for WaaP, an Essential Sugar Kinase Involved in Biosynthesis of Core Lipopolysaccharide of Pseudomonas aeruginosa
Xin Zhao, Cory Q. Wenzel, and Joseph S. Lam
Antimicrob. Agents Chemother. June 2002 46: 2035-2037;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Lentivirus Lytic Peptide 1 Perturbs both Outer and Inner Membranes of Serratia marcescens
Shruti M. Phadke, Vanja Lazarevic, Caroline C. Bahr, Kazi Islam, Donna Beer Stolz, Simon Watkins, Sarah B. Tencza, Hans J. Vogel, Ronald C. Montelaro, and Timothy A. Mietzner
Antimicrob. Agents Chemother. June 2002 46: 2041-2045;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antiviral Agents:

Potency of Nonnucleoside Reverse Transcriptase Inhibitors (NNRTIs) Used in Combination with Other Human Immunodeficiency Virus NNRTIs, NRTIs, or Protease Inhibitors
Robert W. King, Ronald M. Klabe, Carol D. Reid, and Susan K. Erickson-Viitanen
Antimicrob. Agents Chemother. June 2002 46: 1640-1646;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pharmacology of ß-L-Thymidine and ß-L-2'-Deoxycytidine in HepG2 Cells and Primary Human Hepatocytes: Relevance to Chemotherapeutic Efficacy against Hepatitis B Virus
B. Hernandez-Santiago, L. Placidi, E. Cretton-Scott, A. Faraj, E. G. Bridges, M. L. Bryant, J. Rodriguez-Orengo, J. L. Imbach, G. Gosselin, C. Pierra, D. Dukhan, and J. P. Sommadossi
Antimicrob. Agents Chemother. June 2002 46: 1728-1733;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Dose Range Study of Pharmacokinetics, Safety, and Preliminary Antiviral Activity of Emtricitabine in Adults with Hepatitis B Virus Infection
R. G. Gish, N. W. Y. Leung, T. L. Wright, Huy Trinh, W. Lang, H. A. Kessler, L. Fang, L. H. Wang, J. Delehanty, A. Rigney, E. Mondou, A. Snow, and F. Rousseau
Antimicrob. Agents Chemother. June 2002 46: 1734-1740;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Potent In Vivo Antiviral Activity of the Herpes Simplex Virus Primase-Helicase Inhibitor BAY 57-1293
Ulrich A. K. Betz, Rüdiger Fischer, Gerald Kleymann, Martin Hendrix, and Helga Rübsamen-Waigmann
Antimicrob. Agents Chemother. June 2002 46: 1766-1772;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Acyclovir, Ganciclovir, and Zidovudine Transfer into Rat Milk
Jane Alcorn and Patrick J. McNamara
Antimicrob. Agents Chemother. June 2002 46: 1831-1836;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

A Tight-Binding Mode of Inhibition Is Essential for Anti-Human Immunodeficiency Virus Type 1 Virucidal Activity of Nonnucleoside Reverse Transcriptase Inhibitors
Dimitrios Motakis and Michael A. Parniak
Antimicrob. Agents Chemother. June 2002 46: 1851-1856;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Emergence of Resistant Human Immunodeficiency Virus Type 1 in Patients Receiving Fusion Inhibitor (T-20) Monotherapy
Xiping Wei, Julie M. Decker, Hongmei Liu, Zee Zhang, Ramin B. Arani, J. Michael Kilby, Michael S. Saag, Xiaoyun Wu, George M. Shaw, and John C. Kappes
Antimicrob. Agents Chemother. June 2002 46: 1896-1905;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Efficacy of Zidovudine Compared to Stavudine, Both in Combination with Lamivudine and Indinavir, in Human Immunodeficiency Virus-Infected Nucleoside-Experienced Patients with No Prior Exposure to Lamivudine, Stavudine, or Protease Inhibitors (Novavir Trial)
Véronique Joly, Philippe Flandre, Vincent Meiffredy, Françoise Brun-Vezinet, Jean-Albert Gastaut, Cécile Goujard, Gérard Remy, Diane Descamps, Annick Ruffault, Agnès Certain, Jean-Pierre Aboulker, and Patrick Yeni
Antimicrob. Agents Chemother. June 2002 46: 1906-1913;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Longitudinal Use of a Line Probe Assay for Human Immunodeficiency Virus Type 1 Protease Predicts Phenotypic Resistance and Clinical Progression in Patients Failing Highly Active Antiretroviral Therapy
Jean Servais, Christine Lambert, Jean-Marc Plesséria, Elodie Fontaine, Isabelle Robert, Vic Arendt, Thérèse Staub, Robert Hemmer, François Schneider, and Jean-Claude Schmit
Antimicrob. Agents Chemother. June 2002 46: 1928-1933;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Lack of Pharmacokinetic Interaction between the Oral Anti-Influenza Prodrug Oseltamivir and Aspirin
Charles Oo, Joanne Barrett, Albert Dorr, Baolian Liu, and Penelope Ward
Antimicrob. Agents Chemother. June 2002 46: 1993-1995;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Susceptibility:

Reassessment of Clostridium difficile Susceptibility to Metronidazole and Vancomycin
T. Peláez, L. Alcalá, R. Alonso, M. Rodríguez-Créixems, J. M. García-Lechuz, and E. Bouza
Antimicrob. Agents Chemother. June 2002 46: 1647-1650;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activities of Novel Nonfluorinated Quinolones PGE 9262932 and PGE 9509924 against Clinical Isolates of Staphylococcus aureus and Streptococcus pneumoniae with Defined Mutations in DNA Gyrase and Topoisomerase IV
Mark E. Jones, Ian A. Critchley, James A. Karlowsky, Renée S. Blosser-Middleton, Franz-Josef Schmitz, Clyde Thornsberry, and Daniel F. Sahm
Antimicrob. Agents Chemother. June 2002 46: 1651-1657;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Histidine-Rich Protein II: a Novel Approach to Malaria Drug Sensitivity Testing
Harald Noedl, Walther H. Wernsdorfer, Robert Scott Miller, and Chansuda Wongsrichanalai
Antimicrob. Agents Chemother. June 2002 46: 1658-1664;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activities of Ravuconazole and Voriconazole Compared with Those of Four Approved Systemic Antifungal Agents against 6,970 Clinical Isolates of Candida spp.
M. A. Pfaller, S. A. Messer, R. J. Hollis, R. N. Jones, and D. J. Diekema
Antimicrob. Agents Chemother. June 2002 46: 1723-1727;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antifungal Susceptibility of Candida Biofilms: Unique Efficacy of Amphotericin B Lipid Formulations and Echinocandins
D. M. Kuhn, T. George, J. Chandra, P. K. Mukherjee, and M. A. Ghannoum
Antimicrob. Agents Chemother. June 2002 46: 1773-1780;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Precision and Accuracy of Fluconazole Susceptibility Testing by Broth Microdilution, Etest, and Disk Diffusion Methods
A. L. Barry, M. A. Pfaller, R. P. Rennie, P. C. Fuchs, and S. D. Brown
Antimicrob. Agents Chemother. June 2002 46: 1781-1784;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Broad-Spectrum Bactericidal Activity of Ag₂O-Doped Bioactive Glass
Maria Bellantone, Huw D. Williams, and Larry L. Hench
Antimicrob. Agents Chemother. June 2002 46: 1940-1945;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Method for Measuring Postantifungal Effect in Aspergillus Species
Roxana G. Vitale, Johan W. Mouton, Javier Afeltra, Jacques F. G. M. Meis, and Paul E. Verweij
Antimicrob. Agents Chemother. June 2002 46: 1960-1965;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Amphotericin B Formulations Exert Additive Antifungal Activity in Combination with Pulmonary Alveolar Macrophages and Polymorphonuclear Leukocytes against Aspergillus fumigatus
Emmanuel Roilides, Caron A. Lyman, Joanna Filioti, Onome Akpogheneta, Tin Sein, Cristina Gil Lamaignere, Ruta Petraitiene, and Thomas J. Walsh
Antimicrob. Agents Chemother. June 2002 46: 1974-1976;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Effect of Ciprofloxacin on Killing of Actinobacillus actinomycetemcomitans by Polymorphonuclear Leukocytes
David A. Cacchillo and John D. Walters
Antimicrob. Agents Chemother. June 2002 46: 1980-1984;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Determining Linezolid’s Baseline In Vitro Activity in Canada Using Gram-Positive Clinical Isolates Collected prior to Its National Release
James A. Karlowsky, Laurie J. Kelly, Ian A. Critchley, Mark E. Jones, Clyde Thornsberry, and Daniel F. Sahm
Antimicrob. Agents Chemother. June 2002 46: 1989-1992;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Activities of Therapeutic Agents and Myristamidopropyl Dimethylamine against Acanthamoeba Isolates
Simon Kilvington, Reanne Hughes, James Byas, and John Dart
Antimicrob. Agents Chemother. June 2002 46: 2007-2009;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Effects of Synthetic Siderophores on Proliferation of Plasmodium falciparum in Infected Human Erythrocytes
Andrea Rotheneder, Gernot Fritsche, Lothar Heinisch, Ute Möllmann, Susanne Heggemann, Clara Larcher, and Günter Weiss
Antimicrob. Agents Chemother. June 2002 46: 2010-2013;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Combinations of Lysostaphin with ß-Lactams Are Synergistic against Oxacillin-Resistant Staphylococcus epidermidis
Nandini Kiri, Gordon Archer, and Michael W. Climo
Antimicrob. Agents Chemother. June 2002 46: 2017-2020;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Helicobacter pylori Primary Resistance to Metronidazole and Clarithromycin in Brazil
Paula Prazeres Magalhães, Dulciene Maria de Magalhães Queiroz, Daniela Vale Campos Barbosa, Gifone Aguiar Rocha, Edilberto Nogueira Mendes, Adriana Santos, Paulo Renato Valle Corrêa, Andreia Maria Camargos Rocha, Lúcia Martins Teixeira, and Celso Affonso de Oliveira
Antimicrob. Agents Chemother. June 2002 46: 2021-2023;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activities of Pentamidine, Pyrimethamine, Trimethoprim, and Sulfonamides against Aspergillus Species
Javier Afeltra, Jacques F. G. M. Meis, Roxana G. Vitale, Johan W. Mouton, and Paul E. Verweij
Antimicrob. Agents Chemother. June 2002 46: 2029-2031;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antitrypanosomal Activities of Proteasome Inhibitors
Joseph Nkemgu-Njinkeng, Vera Rosenkranz, Michael Wink, and Dietmar Steverding
Antimicrob. Agents Chemother. June 2002 46: 2038-2040;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Effects of Chemical and Physical Agents on Viability and Infectivity of Encephalitozoon intestinalis Determined by Cell Culture and Flow Cytometry
Maud Santillana-Hayat, Claudine Sarfati, Sandra Fournier, Françoise Chau, Raphaël Porcher, Jean-Michel Molina, and Francis Derouin
Antimicrob. Agents Chemother. June 2002 46: 2049-2051;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Experimental Therapeutics:

Pharmacodynamics of the New Fluoroquinolone Gatifloxacin in Murine Thigh and Lung Infection Models
D. Andes and W. A. Craig
Antimicrob. Agents Chemother. June 2002 46: 1665-1670;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Comparison of the Effects of Deferiprone versus Deferoxamine on Growth and Virulence of Yersinia enterocolitica
Biliana Lesic, Jeannine Foulon, and Elisabeth Carniel
Antimicrob. Agents Chemother. June 2002 46: 1741-1745;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Evaluation of T-3811ME (BMS-284756), a New Des-F(6)-Quinolone, for Treatment of Meningitis Caused by Penicillin-Resistant Streptococcus pneumoniae in Rabbits
Masahiro Takahata, Hiroshi Yamada, Teiichi Morita, Shinichi Furubou, Shinzaburo Minami, Yozo Todo, Yasuo Watanabe, and Hirokazu Narita
Antimicrob. Agents Chemother. June 2002 46: 1760-1765;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Activity of Novispirin G10 against Pseudomonas aeruginosa In Vitro and in Infected Burns
Lars Steinstraesser, Brian F. Tack, Alan J. Waring, Teresa Hong, Lee M. Boo, Ming-Hui Fan, Daniel I. Remick, Grace L. Su, Robert I. Lehrer, and Stewart C. Wang
Antimicrob. Agents Chemother. June 2002 46: 1837-1844;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Comparative Antifungal Activities and Plasma Pharmacokinetics of Micafungin (FK463) against Disseminated Candidiasis and Invasive Pulmonary Aspergillosis in Persistently Neutropenic Rabbits
Vidmantas Petraitis, Ruta Petraitiene, Andreas H. Groll, Kristin Roussillon, Melissa Hemmings, Caron A. Lyman, Tin Sein, John Bacher, Ihor Bekersky, and Thomas J. Walsh
Antimicrob. Agents Chemother. June 2002 46: 1857-1869;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Bactericidal Activity of Increasing Daily and Weekly Doses of Moxifloxacin in Murine Tuberculosis
Tetsuyuki Yoshimatsu, Eric Nuermberger, Sandeep Tyagi, Richard Chaisson, William Bishai, and Jacques Grosset
Antimicrob. Agents Chemother. June 2002 46: 1875-1879;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Use of IMiD3, a Thalidomide Analog, as an Adjunct to Therapy for Experimental Tuberculous Meningitis
Liana Tsenova, Bande Mangaliso, George Muller, Yong Chen, Victoria H. Freedman, David Stirling, and Gilla Kaplan
Antimicrob. Agents Chemother. June 2002 46: 1887-1895;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Efficacy of Colistin versus ß-Lactams, Aminoglycosides, and Rifampin as Monotherapy in a Mouse Model of Pneumonia Caused by Multiresistant Acinetobacter baumannii
A. Montero, J. Ariza, X. Corbella, A. Doménech, C. Cabellos, J. Ayats, F. Tubau, C. Ardanuy, and F. Gudiol
Antimicrob. Agents Chemother. June 2002 46: 1946-1952;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Efficacy of Antifungal Therapy in a Nonneutropenic Murine Model of Zygomycosis
Eric Dannaoui, Johan W. Mouton, Jacques F. G. M. Meis, and Paul E. Verweij
Antimicrob. Agents Chemother. June 2002 46: 1953-1959;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Reducing Mortality in Salmonella enterica Serovar Typhimurium-Infected Mice with a Tripeptidic Serum Fraction
Todd A. Parker, Kenneth O. Willeford, Suzanne Parker, and Karyl Buddington
Antimicrob. Agents Chemother. June 2002 46: 1971-1973;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Efficacy of ß-Lactams for Treating Experimentally Induced Pneumonia Due to a Carbapenem-Hydrolyzing Metallo-ß-Lactamase-Producing Strain of Pseudomonas aeruginosa
Samuel Bellais, Olivier Mimoz, Sophie Léotard, Anne Jacolot, Olivier Petitjean, and Patrice Nordmann
Antimicrob. Agents Chemother. June 2002 46: 2032-2034;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pharmacodynamics of Moxifloxacin against Streptococcus pyogenes in an In Vitro Kinetic Model
Inga Odenholt, Elisabeth Löwdin, Ingegerd Gustafsson, and Otto Cars
Antimicrob. Agents Chemother. June 2002 46: 2046-2048;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Clinical Therapeutics:

High Prevalence of High-Level Ciprofloxacin Resistance in Neisseria gonorrhoeae in Tel Aviv, Israel: Correlation with Response to Therapy
Michael Dan, Francesca Poch, and Bracha Sheinberg
Antimicrob. Agents Chemother. June 2002 46: 1671-1673;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Randomized Controlled Trial of Sequential Intravenous (i.v.) and Oral Moxifloxacin Compared with Sequential i.v. and Oral Co-Amoxiclav with or without Clarithromycin in Patients with Community-Acquired Pneumonia Requiring Initial Parenteral Treatment
R. Finch, D. Schürmann, O. Collins, R. Kubin, J. McGivern, H. Bobbaers, J. L. Izquierdo, P. Nikolaides, F. Ogundare, R. Raz, P. Zuck, and G. Hoeffken
Antimicrob. Agents Chemother. June 2002 46: 1746-1754;
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Double-Blind, Randomized, Placebo-Controlled Study of Topical 5% Acyclovir-1% Hydrocortisone Cream (ME-609) for Treatment of UV Radiation-Induced Herpes Labialis
T. G. Evans, D. I. Bernstein, G. W. Raborn, J. Harmenberg, J. Kowalski, and S. L. Spruance
Antimicrob. Agents Chemother. June 2002 46: 1870-1874;
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Pharmacology:

Synergistic Effect of Ofloxacin and Magnesium Deficiency on Joint Cartilage in Immature Rats
Edith Lozo, Kai Riecke, Rudolf Schwabe, Jürgen Vormann, and Ralf Stahlmann
Antimicrob. Agents Chemother. June 2002 46: 1755-1759;
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Chemistry; Biosynthesis:

Identification of a Series of Tricyclic Natural Products as Potent Broad-Spectrum Inhibitors of Metallo-ß-Lactamases
David J. Payne, Juan Antonio Hueso-Rodríguez, Helen Boyd, Néstor O. Concha, Cheryl A. Janson, Martin Gilpin, John H. Bateson, Christy Cheever, Nancy L. Niconovich, Stewart Pearson, Stephen Rittenhouse, David Tew, Emilio Díez, Paloma Pérez, Jesus de la Fuente, Michael Rees, and Alfonso Rivera-Sagredo
Antimicrob. Agents Chemother. June 2002 46: 1880-1886;
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Letters:

Specific gyrA Mutation at Codon 83 in Nalidixic Acid-Resistant Salmonella enterica Serovar Typhi Strains Isolated from Vietnamese Patients
Le Van Phung, Haruko Ryo, and Taisei Nomura
Antimicrob. Agents Chemother. June 2002 46: 2052-2053;
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Identification of a Complete dfrA14 Gene Cassette Integrated at a Secondary Site in a Resistance Plasmid of Uropathogenic Escherichia coli from Nigeria
Kayode K. Ojo, Corinna Kehrenberg, Stefan Schwarz, and H. Akin Odelola
Antimicrob. Agents Chemother. June 2002 46: 2054-2055;
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The Extended-Spectrum K1 ß-Lactamase from Klebsiella oxytoca SC 10,436 Is a Member of the bla_OXY-2 Family of Chromosomal Klebsiella Enzymes
Sophie A. Granier, Véronique Leflon-Guibout, Marie-Hélène Nicolas-Chanoine, Karen Bush, and Fred W. Goldstein
Antimicrob. Agents Chemother. June 2002 46: 2056-2057;
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Integration of Integrons in res Sites
Fabio Tosini, Ruth M. Hall, H. W. Stokes, and Sally R. Partridge
Antimicrob. Agents Chemother. June 2002 46: 2058
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