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Mechanisms of Action:

Robert W. Hong, Mikhail Shchepetov, Jeffrey N. Weiser, and Paul H. Axelsen

Transcriptional Profile of the Escherichia coli Response to the Antimicrobial Insect Peptide Cecropin A
Antimicrob. Agents Chemother. 2003 47: 1-6. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

M. P. Singh, P. J. Petersen, W. J. Weiss, J. E. Janso, S. W. Luckman, E. B. Lenoy, P. A. Bradford, R. T. Testa, and M. Greenstein

Mannopeptimycins, New Cyclic Glycopeptide Antibiotics Produced by Streptomyces hygroscopicus LL-AC98: Antibacterial and Mechanistic Activities
Antimicrob. Agents Chemother. 2003 47: 62-69. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Deirdre H. Fitzgerald, David C. Coleman, and Brian C. O'Connell

Susceptibility of Candida dubliniensis to Salivary Histatin 3
Antimicrob. Agents Chemother. 2003 47: 70-76. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ryuta Kishii, Masaya Takei, Hideyuki Fukuda, Katsuhiko Hayashi, and Masaki Hosaka

Contribution of the 8-Methoxy Group to the Activity of Gatifloxacin against Type II Topoisomerases of Streptococcus pneumoniae
Antimicrob. Agents Chemother. 2003 47: 77-81. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Carole Di Giorgio, Florence Delmas, Nathalie Filloux, Maxime Robin, Laetitia Seferian, Nadine Azas, Monique Gasquet, Muriel Costa, Pierre Timon-David, and Jean-Pierre Galy

In Vitro Activities of 7-Substituted 9-Chloro and 9-Amino-2-Methoxyacridines and Their Bis- and Tetra-Acridine Complexes against Leishmania infantum
Antimicrob. Agents Chemother. 2003 47: 174-180. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Eliana Rodríguez and Magela Laviña

The Proton Channel Is the Minimal Structure of ATP Synthase Necessary and Sufficient for Microcin H47 Antibiotic Action
Antimicrob. Agents Chemother. 2003 47: 181-187. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Zhengyu Feng and Raúl G. Barletta

Roles of Mycobacterium smegmatis D-Alanine:D-Alanine Ligase and D-Alanine Racemase in the Mechanisms of Action of and Resistance to the Peptidoglycan Inhibitor D-Cycloserine
Antimicrob. Agents Chemother. 2003 47: 283-291. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Momcilo Vidakovic, Chetlen R. Crossnoe, Christopher Neidre, Kyonghee Kim, Kurt L. Krause, and Juris P. Germanas

Reactivity of Reduced [2Fe-2S] Ferredoxins Parallels Host Susceptibility to Nitroimidazoles
Antimicrob. Agents Chemother. 2003 47: 302-308. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

J. M. Loeffler and V. A. Fischetti

Synergistic Lethal Effect of a Combination of Phage Lytic Enzymes with Different Activities on Penicillin-Sensitive and -Resistant Streptococcus pneumoniae Strains
Antimicrob. Agents Chemother. 2003 47: 375-377. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Michael S. Scherman, Katharine A. Winans, Richard J. Stern, Victoria Jones, Carolyn R. Bertozzi, and Michael R. McNeil

Drug Targeting Mycobacterium tuberculosis Cell Wall Synthesis: Development of a Microtiter Plate-Based Screen for UDP-Galactopyranose Mutase and Identification of an Inhibitor from a Uridine-Based Library
Antimicrob. Agents Chemother. 2003 47: 378-382. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Resistance:

Florence Depardieu, Peter E. Reynolds, and Patrice Courvalin

VanD-Type Vancomycin-Resistant Enterococcus faecium 10/96A
Antimicrob. Agents Chemother. 2003 47: 7-18. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Thierry Naas, Marie Zerbib, Delphine Girlich, and Patrice Nordmann

Integration of a Transposon Tn1-Encoded Inhibitor-Resistant ß-Lactamase Gene, bla_TEM-67 from Proteus mirabilis, into the Escherichia coli Chromosome
Antimicrob. Agents Chemother. 2003 47: 19-26. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Xian-Zhi Li, Keith Poole, and Hiroshi Nikaido

Contributions of MexAB-OprM and an EmrE Homolog to Intrinsic Resistance of Pseudomonas aeruginosa to Aminoglycosides and Dyes
Antimicrob. Agents Chemother. 2003 47: 27-33. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pranab K. Mukherjee, Steven D. Leidich, Nancy Isham, Ingrid Leitner, Neil S. Ryder, and Mahmoud A. Ghannoum

Clinical Trichophyton rubrum Strain Exhibiting Primary Resistance to Terbinafine
Antimicrob. Agents Chemother. 2003 47: 82-86. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pharath Lim, Sophy Chy, Frédéric Ariey, Sandra Incardona, Pektra Chim, Rithy Sem, Mey Bouth Denis, Sean Hewitt, Stefan Hoyer, Doung Socheat, Odile Merecreau-Puijalon, and Thierry Fandeur

pfcrt Polymorphism and Chloroquine Resistance in Plasmodium falciparum Strains Isolated in Cambodia
Antimicrob. Agents Chemother. 2003 47: 87-94. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Yanping Wang, Unhwan Ha, Lin Zeng, and Shouguang Jin

Regulation of Membrane Permeability by a Two-Component Regulatory System in Pseudomonas aeruginosa
Antimicrob. Agents Chemother. 2003 47: 95-101. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Joseph A. DeVito and Sheldon Morris

Exploring the Structure and Function of the Mycobacterial KatG Protein Using trans-Dominant Mutants
Antimicrob. Agents Chemother. 2003 47: 188-195. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

P. D. Fey, B. Saïd-Salim, M. E. Rupp, S. H. Hinrichs, D. J. Boxrud, C. C. Davis, B. N. Kreiswirth, and P. M. Schlievert

Comparative Molecular Analysis of Community- or Hospital-Acquired Methicillin-Resistant Staphylococcus aureus
Antimicrob. Agents Chemother. 2003 47: 196-203. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Janet M. Manson, Stefanie Keis, John M. B. Smith, and Gregory M. Cook

A Clonal Lineage of VanA-Type Enterococcus faecalis Predominates in Vancomycin-Resistant Enterococci Isolated in New Zealand
Antimicrob. Agents Chemother. 2003 47: 204-210. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Antonella Lupetti, Akke Paulusma-Annema, Mick M. Welling, Heleen Dogterom-Ballering, Carlo P. J. M. Brouwer, Sonia Senesi, Jaap T. van Dissel, and Peter H. Nibbering

Synergistic Activity of the N-Terminal Peptide of Human Lactoferrin and Fluconazole against Candida Species
Antimicrob. Agents Chemother. 2003 47: 262-267. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Claire Héritier, Laurent Poirel, Daniel Aubert, and Patrice Nordmann

Genetic and Functional Analysis of the Chromosome-Encoded Carbapenem-Hydrolyzing Oxacillinase OXA-40 of Acinetobacter baumannii
Antimicrob. Agents Chemother. 2003 47: 268-273. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Dilek Ince, Xiamei Zhang, L. Christine Silver, and David C. Hooper

Topoisomerase Targeting with and Resistance to Gemifloxacin in Staphylococcus aureus
Antimicrob. Agents Chemother. 2003 47: 274-282. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Marshall C. Walters, III, Frank Roe, Amandine Bugnicourt, Michael J. Franklin, and Philip S. Stewart

Contributions of Antibiotic Penetration, Oxygen Limitation, and Low Metabolic Activity to Tolerance of Pseudomonas aeruginosa Biofilms to Ciprofloxacin and Tobramycin
Antimicrob. Agents Chemother. 2003 47: 317-323. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sally R. Partridge and Ruth M. Hall

In34, a Complex In5 Family Class 1 Integron Containing orf513 and dfrA10
Antimicrob. Agents Chemother. 2003 47: 342-349. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Michael F. Minnick, Zachary R. Wilson, Laura S. Smitherman, and D. Scott Samuels

gyrA Mutations in Ciprofloxacin-Resistant Bartonella bacilliformis Strains Obtained In Vitro
Antimicrob. Agents Chemother. 2003 47: 383-386. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Anthony M. Smith and Keith P. Klugman

Site-Specific Mutagenesis Analysis of PBP 1A from a Penicillin-Cephalosporin-Resistant Pneumococcal Isolate
Antimicrob. Agents Chemother. 2003 47: 387-389. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Naidan Luo, Orhan Sahin, Jun Lin, Linda O. Michel, and Qijing Zhang

In Vivo Selection of Campylobacter Isolates with High Levels of Fluoroquinolone Resistance Associated with gyrA Mutations and the Function of the CmeABC Efflux Pump
Antimicrob. Agents Chemother. 2003 47: 390-394. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Vivi Miriagou, Eva Tzelepi, Dimitra Gianneli, and Leonidas S. Tzouvelekis

Escherichia coli with a Self-Transferable, Multiresistant Plasmid Coding for Metallo-ß-Lactamase VIM-1
Antimicrob. Agents Chemother. 2003 47: 395-397. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

S. M. Soto, M. J. Lobato, and M. C. Mendoza

Class 1 Integron-Borne Gene Cassettes in Multidrug-Resistant Yersinia enterocolitica Strains of Different Phenotypic and Genetic Types
Antimicrob. Agents Chemother. 2003 47: 421-426. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Miyuki Kumano, Masaya Fujita, Kouji Nakamura, Makiko Murata, Reiko Ohki, and Kunio Yamane

Lincomycin Resistance Mutations in Two Regions Immediately Downstream of the -10 Region of lmr Promoter Cause Overexpression of a Putative Multidrug Efflux Pump in Bacillus subtilis Mutants
Antimicrob. Agents Chemother. 2003 47: 432-435. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kai Man Kam, Shirley Sin Yee Kam, Danny Tze Leung Cheung, Viola Wai Na Tung, Wai Fun Au, and May May Cheung

Molecular Characterization of Quinolone-Resistant Neisseria gonorrhoeae in Hong Kong
Antimicrob. Agents Chemother. 2003 47: 436-439. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Susceptibility:

J. D. Sobel, M. Zervos, B. D. Reed, T. Hooton, D. Soper, P. Nyirjesy, M. W. Heine, J. Willems, and H. Panzer

Fluconazole Susceptibility of Vaginal Isolates Obtained from Women with Complicated Candida Vaginitis: Clinical Implications
Antimicrob. Agents Chemother. 2003 47: 34-38. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ken B. Waites, Donna M. Crabb, and Lynn B. Duffy

In Vitro Activities of ABT-773 and Other Antimicrobials against Human Mycoplasmas
Antimicrob. Agents Chemother. 2003 47: 39-42. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hilpi Rautelin, Antti Vierikko, Marja-Liisa Hänninen, and Martti Vaara

Antimicrobial Susceptibilities of Campylobacter Strains Isolated from Finnish Subjects Infected Domestically or from Those Infected Abroad
Antimicrob. Agents Chemother. 2003 47: 102-105. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Joseph Meletiadis, Johan W. Mouton, Jacques F. G. M. Meis, and Paul E. Verweij

In Vitro Drug Interaction Modeling of Combinations of Azoles with Terbinafine against Clinical Scedosporium prolificans Isolates
Antimicrob. Agents Chemother. 2003 47: 106-117. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

P. Cottagnoud, M. Cottagnoud, and M. G. Täuber

Vancomycin Acts Synergistically with Gentamicin against Penicillin-Resistant Pneumococci by Increasing the Intracellular Penetration of Gentamicin
Antimicrob. Agents Chemother. 2003 47: 144-147. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kenneth E. Aldridge, Deborah Ashcraft, Megan O'Brien, and Charles V. Sanders

Bacteremia Due to Bacteroides fragilis Group: Distribution of Species, ß-Lactamase Production, and Antimicrobial Susceptibility Patterns
Antimicrob. Agents Chemother. 2003 47: 148-153. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Bhaskar R. Shenai, Belinda J. Lee, Alejandro Alvarez-Hernandez, Pek Y. Chong, Cory D. Emal, R. Jeffrey Neitz, William R. Roush, and Philip J. Rosenthal

Structure-Activity Relationships for Inhibition of Cysteine Protease Activity and Development of Plasmodium falciparum by Peptidyl Vinyl Sulfones
Antimicrob. Agents Chemother. 2003 47: 154-160. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ken B. Waites, Donna M. Crabb, Xue Bing, and Lynn B. Duffy

In Vitro Susceptibilities to and Bactericidal Activities of Garenoxacin (BMS-284756) and Other Antimicrobial Agents against Human Mycoplasmas and Ureaplasmas
Antimicrob. Agents Chemother. 2003 47: 161-165. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Edward O. Mason, Jr., Linda B. Lamberth, Ellen R. Wald, John S. Bradley, William J. Barson, and Sheldon L. Kaplan

In Vitro Activities of Cethromycin (ABT-773), a New Ketolide, against Streptococcus pneumoniae Strains That Are Not Susceptible to Penicillin or Macrolides
Antimicrob. Agents Chemother. 2003 47: 166-169. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Bruce M. Russell, Rachanee Udomsangpetch, Karl H. Rieckmann, Barbara M. Kotecka, Russell E. Coleman, and Jetsumon Sattabongkot

Simple In Vitro Assay for Determining the Sensitivity of Plasmodium vivax Isolates from Fresh Human Blood to Antimalarials in Areas where P. vivax Is Endemic
Antimicrob. Agents Chemother. 2003 47: 170-173. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ronald N. Jones, Christopher M. Rubino, Sujata M. Bhavnani, and Paul G. Ambrose

Worldwide Antimicrobial Susceptibility Patterns and Pharmacodynamic Comparisons of Gatifloxacin and Levofloxacin against Streptococcus pneumoniae: Report from the Antimicrobial Resistance Rate Epidemiology Study Team
Antimicrob. Agents Chemother. 2003 47: 292-296. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ross F. Waller, Stuart A. Ralph, Michael B. Reed, Vanessa Su, James D. Douglas, David E. Minnikin, Alan F. Cowman, Gurdyal S. Besra, and Geoffrey I. McFadden

A Type II Pathway for Fatty Acid Biosynthesis Presents Drug Targets in Plasmodium falciparum
Antimicrob. Agents Chemother. 2003 47: 297-301. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Marc-Jan Gubbels, Catherine Li, and Boris Striepen

High-Throughput Growth Assay for Toxoplasma gondii Using Yellow Fluorescent Protein
Antimicrob. Agents Chemother. 2003 47: 309-316. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ellie J. C. Goldstein, Diane M. Citron, C. Vreni Merriam, Yumi A. Warren, Kerrin L. Tyrrell, and Helen T. Fernandez

In Vitro Activities of Daptomycin, Vancomycin, Quinupristin- Dalfopristin, Linezolid, and Five Other Antimicrobials against 307 Gram-Positive Anaerobic and 31 Corynebacterium Clinical Isolates
Antimicrob. Agents Chemother. 2003 47: 337-341. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Brent W. Gunderson, Khalid H. Ibrahim, Charles A. Peloquin, Laurie B. Hovde, and John C. Rotschafer

Comparison of Linezolid Activities under Aerobic and Anaerobic Conditions against Methicillin-Resistant Staphylococcus aureus and Vancomycin-Resistant Enterococcus faecium
Antimicrob. Agents Chemother. 2003 47: 398-399. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

D. Milatovic, F.-J. Schmitz, J. Verhoef, and A. C. Fluit

Activities of the Glycylcycline Tigecycline (GAR-936) against 1,924 Recent European Clinical Bacterial Isolates
Antimicrob. Agents Chemother. 2003 47: 400-404. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Bülent Bozdogan, Catherine Clark, Andre Bryskier, Michael R. Jacobs, and Peter C. Appelbaum

Activities of HMR 3787 and RU 64399 Compared with Those of Four Other Agents against Haemophilus influenzae and Haemophilus parainfluenzae
Antimicrob. Agents Chemother. 2003 47: 405-407. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pier Carlo Braga, Cinzia Bovio, Maria Culici, and Monica Dal Sasso

Flow Cytometric Assessment of Susceptibilities of Streptococcus pyogenes to Erythromycin and Rokitamycin
Antimicrob. Agents Chemother. 2003 47: 408-412. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Max Maurin, Johan S. Bakken, and J. Stephen Dumler

Antibiotic Susceptibilities of Anaplasma (Ehrlichia) phagocytophilum Strains from Various Geographic Areas in the United States
Antimicrob. Agents Chemother. 2003 47: 413-415. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Luis Alcalá, María Jesús Ruiz-Serrano, Cristina Pérez-Fernández Turégano, Darío García de Viedma, Marisol Díaz-Infantes, Mercedes Marín-Arriaza, and Emilio Bouza

In Vitro Activities of Linezolid against Clinical Isolates of Mycobacterium tuberculosis That Are Susceptible or Resistant to First-Line Antituberculous Drugs
Antimicrob. Agents Chemother. 2003 47: 416-417. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Patrick Grohs, Marie-Dominique Kitzis, and Laurent Gutmann

In Vitro Bactericidal Activities of Linezolid in Combination with Vancomycin, Gentamicin, Ciprofloxacin, Fusidic Acid, and Rifampin against Staphylococcus aureus
Antimicrob. Agents Chemother. 2003 47: 418-420. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Experimental Therapeutics:

David C. Griffith, Laurie Harford, Robert Williams, Ving J. Lee, and Michael N. Dudley

In Vivo Antibacterial Activity of RWJ-54428, a New Cephalosporin with Activity against Gram-Positive Bacteria
Antimicrob. Agents Chemother. 2003 47: 43-47. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Marc Pfister, Liping Zhang, Margareta Hammarlund-Udenaes, Lewis B. Sheiner, Cynthia M. Gerber, Martin G. Täuber, and Philippe Cottagnoud

Modeling of Transfer Kinetics at the Serum-Cerebrospinal Fluid Barrier in Rabbits with Experimental Meningitis: Application to Grepafloxacin
Antimicrob. Agents Chemother. 2003 47: 138-143. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Violeta Rodriguez-Cerrato, Cindy C. McCoig, Jesus Saavedra, Tess Barton, Ian C. Michelow, Robert D. Hardy, Karen Bowlware, Janie Iglehart, Kathy Katz, and George H. McCracken, Jr

Garenoxacin (BMS-284756) and Moxifloxacin in Experimental Meningitis Caused by Vancomycin-Tolerant Pneumococci
Antimicrob. Agents Chemother. 2003 47: 211-215. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Agnès Lefort, Matthieu Lafaurie, Laurent Massias, Yolande Petegnief, Azzam Saleh-Mghir, Claudette Muller-Serieys, Dominique Le Guludec, and Bruno Fantin

Activity and Diffusion of Tigecycline (GAR-936) in Experimental Enterococcal Endocarditis
Antimicrob. Agents Chemother. 2003 47: 216-222. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Max Jean de Ornelas Toledo, Maria Terezinha Bahia, Cláudia M. Carneiro, Olindo Assis Martins-Filho, Michel Tibayrenc, Christian Barnabé, Washington Luis Tafuri, and Marta de Lana

Chemotherapy with Benznidazole and Itraconazole for Mice Infected with Different Trypanosoma cruzi Clonal Genotypes
Antimicrob. Agents Chemother. 2003 47: 223-230. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Lanfranco Fattorini, Dejiang Tan, Elisabetta Iona, Maurizio Mattei, Federico Giannoni, Lara Brunori, Simona Recchia, and Graziella Orefici

Activities of Moxifloxacin Alone and in Combination with Other Antimicrobial Agents against Multidrug-Resistant Mycobacterium tuberculosis Infection in BALB/c Mice
Antimicrob. Agents Chemother. 2003 47: 360-362. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Biologic Response Modifiers:

Takeshi Yamaryo, Kazunori Oishi, Hiroyuki Yoshimine, Yoshiko Tsuchihashi, Kouji Matsushima, and Tsuyoshi Nagatake

Fourteen-Member Macrolides Promote the Phosphatidylserine Receptor-Dependent Phagocytosis of Apoptotic Neutrophils by Alveolar Macrophages
Antimicrob. Agents Chemother. 2003 47: 48-53. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Tetsuji Nakano, Kazufumi Hiramatsu, Kenji Kishi, Norio Hirata, Jun-ichi Kadota, and Masaru Nasu

Clindamycin Modulates Inflammatory-Cytokine Induction in Lipopolysaccharide-Stimulated Mouse Peritoneal Macrophages
Antimicrob. Agents Chemother. 2003 47: 363-367. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Antiviral Agents:

Martin Stürmer, Schlomo Staszewski, Hans-Wilhelm Doerr, Brendan Larder, Stuart Bloor, and Kurt Hertogs

Correlation of Phenotypic Zidovudine Resistance with Mutational Patterns in the Reverse Transcriptase of Human Immunodeficiency Virus Type 1: Interpretation of Established Mutations and Characterization of New Polymorphisms at Codons 208, 211, and 214
Antimicrob. Agents Chemother. 2003 47: 54-61. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sylvie Larrat, Françoise Stanke-Labesque, Agnès Plages, Jean-Pierre Zarski, Germain Bessard, and Claude Souvignet

Ribavirin Quantification in Combination Treatment of Chronic Hepatitis C
Antimicrob. Agents Chemother. 2003 47: 124-129. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Marc Pfister, Line Labbé, Scott M. Hammer, John Mellors, Kara K. Bennett, Susan Rosenkranz, and Lewis B. Sheiner

Population Pharmacokinetics and Pharmacodynamics of Efavirenz, Nelfinavir, and Indinavir: Adult AIDS Clinical Trial Group Study 398
Antimicrob. Agents Chemother. 2003 47: 130-137. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Lieven J. Stuyver, Tony Whitaker, Tamara R. McBrayer, Brenda I. Hernandez-Santiago, Stefania Lostia, Phillip M. Tharnish, Mangala Ramesh, Chung K. Chu, Robert Jordan, Junxing Shi, Suguna Rachakonda, Kyoichi A. Watanabe, Michael J. Otto, and Raymond F. Schinazi

Ribonucleoside Analogue That Blocks Replication of Bovine Viral Diarrhea and Hepatitis C Viruses in Culture
Antimicrob. Agents Chemother. 2003 47: 244-254. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Stephen Kewn, Laurene H. Wang, Patrick G. Hoggard, Franck Rousseau, Robert Hart, John P. MacNeela, Saye H. Khoo, and David J. Back

Enzymatic Assay for Measurement of Intracellular DXG Triphosphate Concentrations in Peripheral Blood Mononuclear Cells from Human Immunodeficiency Virus Type 1-Infected Patients
Antimicrob. Agents Chemother. 2003 47: 255-261. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ayman M. Abdelhamed, Colleen M. Kelley, Thomas G. Miller, Phillip A. Furman, Edward E. Cable, and Harriet C. Isom

Comparison of Anti-Hepatitis B Virus Activities of Lamivudine and Clevudine by a Quantitative Assay
Antimicrob. Agents Chemother. 2003 47: 324-336. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ann Hsu, Jeffrey Isaacson, Scott Brun, Barry Bernstein, Wayne Lam, Richard Bertz, Cheryl Foit, Karen Rynkiewicz, Bruce Richards, Martin King, Richard Rode, Dale J. Kempf, G. Richard Granneman, and Eugene Sun

Pharmacokinetic-Pharmacodynamic Analysis of Lopinavir-Ritonavir in Combination with Efavirenz and Two Nucleoside Reverse Transcriptase Inhibitors in Extensively Pretreated Human Immunodeficiency Virus-Infected Patients
Antimicrob. Agents Chemother. 2003 47: 350-359. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jim Zhen Wu, Heli Walker, Johnson Y. N. Lau, and Zhi Hong

Activation and Deactivation of a Broad-Spectrum Antiviral Drug by a Single Enzyme: Adenosine Deaminase Catalyzes Two Consecutive Deamination Reactions
Antimicrob. Agents Chemother. 2003 47: 426-431. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pharmacology:

Cecile Goujard, Isabelle Vincent, Jean-Luc Meynard, Nathalie Choudet, Diane Bollens, Cyril Rousseau, Didier Demarles, Catherine Gillotin, Roselyne Bidault, and Anne-Marie Taburet

Steady-State Pharmacokinetics of Amprenavir Coadministered with Ritonavir in Human Immunodeficiency Virus Type 1-Infected Patients
Antimicrob. Agents Chemother. 2003 47: 118-123. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Caroline Solas, Alain Lafeuillade, Philippe Halfon, Stéphane Chadapaud, Gilles Hittinger, and Bruno Lacarelle

Discrepancies between Protease Inhibitor Concentrations and Viral Load in Reservoirs and Sanctuary Sites in Human Immunodeficiency Virus-Infected Patients
Antimicrob. Agents Chemother. 2003 47: 238-243. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Timothy M. E. Davis, Tran Quang Binh, Kenneth F. Ilett, Kevin T. Batty, Hoang Lan Phuöng, Gregory M. Chiswell, Vu Duong Bich Phuong, and Cindy Agus

Penetration of Dihydroartemisinin into Cerebrospinal Fluid after Administration of Intravenous Artesunate in Severe Falciparum Malaria
Antimicrob. Agents Chemother. 2003 47: 368-370. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

F. J. Legat, A. Maier, P. Dittrich, P. Zenahlik, T. Kern, S. Nuhsbaumer, M. Frossard, W. Salmhofer, H. Kerl, and M. Müller

Penetration of Fosfomycin into Inflammatory Lesions in Patients with Cellulitis or Diabetic Foot Syndrome
Antimicrob. Agents Chemother. 2003 47: 371-374. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Clinical Therapeutics:

Agnès Aubouy, Mohamed Bakary, Annick Keundjian, Bernard Mbomat, Jean Ruffin Makita, Florence Migot-Nabias, Michel Cot, Jacques Le Bras, and Philippe Deloron

Combination of Drug Level Measurement and Parasite Genotyping Data for Improved Assessment of Amodiaquine and Sulfadoxine-Pyrimethamine Efficacies in Treating Plasmodium falciparum Malaria in Gabonese Children
Antimicrob. Agents Chemother. 2003 47: 231-237. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Letters:

Glen T. Hansen, Kelli Metzler, Karl Drlica, and Joseph M. Blondeau

Mutant Prevention Concentration of Gemifloxacin for Clinical Isolates of Streptococcus pneumoniae
Antimicrob. Agents Chemother. 2003 47: 440-441. [Full Text] [PDF] [Reprints and Permissions]  

Tobias Eckle, Gerhard Jahn, and Klaus Hamprecht

High Impact of an Expanded Restriction Fragment Length Polymorphism Assay on Detection of Ganciclovir-Resistant UL97 Mutants of Human Cytomegalovirus
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