AAC -- Table of Contents (January 1 2003, 47 [1])

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Contents: January 2003, Volume 47, Issue 1

       Mechanisms of Action

       Mechanisms of Resistance

       Susceptibility

       Experimental Therapeutics

       Biologic Response Modifiers

       Antiviral Agents

       Pharmacology

       Clinical Therapeutics

       Letters

Other Issues

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Table of Contents

[Index by Author]

To see an article, click its [Full Text], [Abstract] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

Mechanisms of Action:

Transcriptional Profile of the Escherichia coli Response to the Antimicrobial Insect Peptide Cecropin A
Robert W. Hong, Mikhail Shchepetov, Jeffrey N. Weiser, and Paul H. Axelsen
Antimicrob. Agents Chemother. January 2003 47: 1-6;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mannopeptimycins, New Cyclic Glycopeptide Antibiotics Produced by Streptomyces hygroscopicus LL-AC98: Antibacterial and Mechanistic Activities
M. P. Singh, P. J. Petersen, W. J. Weiss, J. E. Janso, S. W. Luckman, E. B. Lenoy, P. A. Bradford, R. T. Testa, and M. Greenstein
Antimicrob. Agents Chemother. January 2003 47: 62-69;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Susceptibility of Candida dubliniensis to Salivary Histatin 3
Deirdre H. Fitzgerald, David C. Coleman, and Brian C. O'Connell
Antimicrob. Agents Chemother. January 2003 47: 70-76;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Contribution of the 8-Methoxy Group to the Activity of Gatifloxacin against Type II Topoisomerases of Streptococcus pneumoniae
Ryuta Kishii, Masaya Takei, Hideyuki Fukuda, Katsuhiko Hayashi, and Masaki Hosaka
Antimicrob. Agents Chemother. January 2003 47: 77-81;
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In Vitro Activities of 7-Substituted 9-Chloro and 9-Amino-2-Methoxyacridines and Their Bis- and Tetra-Acridine Complexes against Leishmania infantum
Carole Di Giorgio, Florence Delmas, Nathalie Filloux, Maxime Robin, Laetitia Seferian, Nadine Azas, Monique Gasquet, Muriel Costa, Pierre Timon-David, and Jean-Pierre Galy
Antimicrob. Agents Chemother. January 2003 47: 174-180;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

The Proton Channel Is the Minimal Structure of ATP Synthase Necessary and Sufficient for Microcin H47 Antibiotic Action
Eliana Rodríguez and Magela Laviña
Antimicrob. Agents Chemother. January 2003 47: 181-187;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Roles of Mycobacterium smegmatis D-Alanine:D-Alanine Ligase and D-Alanine Racemase in the Mechanisms of Action of and Resistance to the Peptidoglycan Inhibitor D-Cycloserine
Zhengyu Feng and Raúl G. Barletta
Antimicrob. Agents Chemother. January 2003 47: 283-291;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Reactivity of Reduced [2Fe-2S] Ferredoxins Parallels Host Susceptibility to Nitroimidazoles
Momcilo Vidakovic, Chetlen R. Crossnoe, Christopher Neidre, Kyonghee Kim, Kurt L. Krause, and Juris P. Germanas
Antimicrob. Agents Chemother. January 2003 47: 302-308;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Synergistic Lethal Effect of a Combination of Phage Lytic Enzymes with Different Activities on Penicillin-Sensitive and -Resistant Streptococcus pneumoniae Strains
J. M. Loeffler and V. A. Fischetti
Antimicrob. Agents Chemother. January 2003 47: 375-377;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Drug Targeting Mycobacterium tuberculosis Cell Wall Synthesis: Development of a Microtiter Plate-Based Screen for UDP-Galactopyranose Mutase and Identification of an Inhibitor from a Uridine-Based Library
Michael S. Scherman, Katharine A. Winans, Richard J. Stern, Victoria Jones, Carolyn R. Bertozzi, and Michael R. McNeil
Antimicrob. Agents Chemother. January 2003 47: 378-382;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mechanisms of Resistance:

VanD-Type Vancomycin-Resistant Enterococcus faecium 10/96A
Florence Depardieu, Peter E. Reynolds, and Patrice Courvalin
Antimicrob. Agents Chemother. January 2003 47: 7-18;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Integration of a Transposon Tn1-Encoded Inhibitor-Resistant ß-Lactamase Gene, bla_TEM-67 from Proteus mirabilis, into the Escherichia coli Chromosome
Thierry Naas, Marie Zerbib, Delphine Girlich, and Patrice Nordmann
Antimicrob. Agents Chemother. January 2003 47: 19-26;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Contributions of MexAB-OprM and an EmrE Homolog to Intrinsic Resistance of Pseudomonas aeruginosa to Aminoglycosides and Dyes
Xian-Zhi Li, Keith Poole, and Hiroshi Nikaido
Antimicrob. Agents Chemother. January 2003 47: 27-33;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Clinical Trichophyton rubrum Strain Exhibiting Primary Resistance to Terbinafine
Pranab K. Mukherjee, Steven D. Leidich, Nancy Isham, Ingrid Leitner, Neil S. Ryder, and Mahmoud A. Ghannoum
Antimicrob. Agents Chemother. January 2003 47: 82-86;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

pfcrt Polymorphism and Chloroquine Resistance in Plasmodium falciparum Strains Isolated in Cambodia
Pharath Lim, Sophy Chy, Frédéric Ariey, Sandra Incardona, Pektra Chim, Rithy Sem, Mey Bouth Denis, Sean Hewitt, Stefan Hoyer, Doung Socheat, Odile Merecreau-Puijalon, and Thierry Fandeur
Antimicrob. Agents Chemother. January 2003 47: 87-94;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Regulation of Membrane Permeability by a Two-Component Regulatory System in Pseudomonas aeruginosa
Yanping Wang, Unhwan Ha, Lin Zeng, and Shouguang Jin
Antimicrob. Agents Chemother. January 2003 47: 95-101;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Exploring the Structure and Function of the Mycobacterial KatG Protein Using trans-Dominant Mutants
Joseph A. DeVito and Sheldon Morris
Antimicrob. Agents Chemother. January 2003 47: 188-195;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Comparative Molecular Analysis of Community- or Hospital-Acquired Methicillin-Resistant Staphylococcus aureus
P. D. Fey, B. Saïd-Salim, M. E. Rupp, S. H. Hinrichs, D. J. Boxrud, C. C. Davis, B. N. Kreiswirth, and P. M. Schlievert
Antimicrob. Agents Chemother. January 2003 47: 196-203;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

A Clonal Lineage of VanA-Type Enterococcus faecalis Predominates in Vancomycin-Resistant Enterococci Isolated in New Zealand
Janet M. Manson, Stefanie Keis, John M. B. Smith, and Gregory M. Cook
Antimicrob. Agents Chemother. January 2003 47: 204-210;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Synergistic Activity of the N-Terminal Peptide of Human Lactoferrin and Fluconazole against Candida Species
Antonella Lupetti, Akke Paulusma-Annema, Mick M. Welling, Heleen Dogterom-Ballering, Carlo P. J. M. Brouwer, Sonia Senesi, Jaap T. van Dissel, and Peter H. Nibbering
Antimicrob. Agents Chemother. January 2003 47: 262-267;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Genetic and Functional Analysis of the Chromosome-Encoded Carbapenem-Hydrolyzing Oxacillinase OXA-40 of Acinetobacter baumannii
Claire Héritier, Laurent Poirel, Daniel Aubert, and Patrice Nordmann
Antimicrob. Agents Chemother. January 2003 47: 268-273;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Topoisomerase Targeting with and Resistance to Gemifloxacin in Staphylococcus aureus
Dilek Ince, Xiamei Zhang, L. Christine Silver, and David C. Hooper
Antimicrob. Agents Chemother. January 2003 47: 274-282;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Contributions of Antibiotic Penetration, Oxygen Limitation, and Low Metabolic Activity to Tolerance of Pseudomonas aeruginosa Biofilms to Ciprofloxacin and Tobramycin
Marshall C. Walters, III, Frank Roe, Amandine Bugnicourt, Michael J. Franklin, and Philip S. Stewart
Antimicrob. Agents Chemother. January 2003 47: 317-323;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

In34, a Complex In5 Family Class 1 Integron Containing orf513 and dfrA10
Sally R. Partridge and Ruth M. Hall
Antimicrob. Agents Chemother. January 2003 47: 342-349;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

gyrA Mutations in Ciprofloxacin-Resistant Bartonella bacilliformis Strains Obtained In Vitro
Michael F. Minnick, Zachary R. Wilson, Laura S. Smitherman, and D. Scott Samuels
Antimicrob. Agents Chemother. January 2003 47: 383-386;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Site-Specific Mutagenesis Analysis of PBP 1A from a Penicillin-Cephalosporin-Resistant Pneumococcal Isolate
Anthony M. Smith and Keith P. Klugman
Antimicrob. Agents Chemother. January 2003 47: 387-389;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vivo Selection of Campylobacter Isolates with High Levels of Fluoroquinolone Resistance Associated with gyrA Mutations and the Function of the CmeABC Efflux Pump
Naidan Luo, Orhan Sahin, Jun Lin, Linda O. Michel, and Qijing Zhang
Antimicrob. Agents Chemother. January 2003 47: 390-394;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Escherichia coli with a Self-Transferable, Multiresistant Plasmid Coding for Metallo-ß-Lactamase VIM-1
Vivi Miriagou, Eva Tzelepi, Dimitra Gianneli, and Leonidas S. Tzouvelekis
Antimicrob. Agents Chemother. January 2003 47: 395-397;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Class 1 Integron-Borne Gene Cassettes in Multidrug-Resistant Yersinia enterocolitica Strains of Different Phenotypic and Genetic Types
S. M. Soto, M. J. Lobato, and M. C. Mendoza
Antimicrob. Agents Chemother. January 2003 47: 421-426;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Lincomycin Resistance Mutations in Two Regions Immediately Downstream of the -10 Region of lmr Promoter Cause Overexpression of a Putative Multidrug Efflux Pump in Bacillus subtilis Mutants
Miyuki Kumano, Masaya Fujita, Kouji Nakamura, Makiko Murata, Reiko Ohki, and Kunio Yamane
Antimicrob. Agents Chemother. January 2003 47: 432-435;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Molecular Characterization of Quinolone-Resistant Neisseria gonorrhoeae in Hong Kong
Kai Man Kam, Shirley Sin Yee Kam, Danny Tze Leung Cheung, Viola Wai Na Tung, Wai Fun Au, and May May Cheung
Antimicrob. Agents Chemother. January 2003 47: 436-439;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Susceptibility:

Fluconazole Susceptibility of Vaginal Isolates Obtained from Women with Complicated Candida Vaginitis: Clinical Implications
J. D. Sobel, M. Zervos, B. D. Reed, T. Hooton, D. Soper, P. Nyirjesy, M. W. Heine, J. Willems, and H. Panzer
Antimicrob. Agents Chemother. January 2003 47: 34-38;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activities of ABT-773 and Other Antimicrobials against Human Mycoplasmas
Ken B. Waites, Donna M. Crabb, and Lynn B. Duffy
Antimicrob. Agents Chemother. January 2003 47: 39-42;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antimicrobial Susceptibilities of Campylobacter Strains Isolated from Finnish Subjects Infected Domestically or from Those Infected Abroad
Hilpi Rautelin, Antti Vierikko, Marja-Liisa Hänninen, and Martti Vaara
Antimicrob. Agents Chemother. January 2003 47: 102-105;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Drug Interaction Modeling of Combinations of Azoles with Terbinafine against Clinical Scedosporium prolificans Isolates
Joseph Meletiadis, Johan W. Mouton, Jacques F. G. M. Meis, and Paul E. Verweij
Antimicrob. Agents Chemother. January 2003 47: 106-117;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Vancomycin Acts Synergistically with Gentamicin against Penicillin-Resistant Pneumococci by Increasing the Intracellular Penetration of Gentamicin
P. Cottagnoud, M. Cottagnoud, and M. G. Täuber
Antimicrob. Agents Chemother. January 2003 47: 144-147;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Bacteremia Due to Bacteroides fragilis Group: Distribution of Species, ß-Lactamase Production, and Antimicrobial Susceptibility Patterns
Kenneth E. Aldridge, Deborah Ashcraft, Megan O'Brien, and Charles V. Sanders
Antimicrob. Agents Chemother. January 2003 47: 148-153;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Structure-Activity Relationships for Inhibition of Cysteine Protease Activity and Development of Plasmodium falciparum by Peptidyl Vinyl Sulfones
Bhaskar R. Shenai, Belinda J. Lee, Alejandro Alvarez-Hernandez, Pek Y. Chong, Cory D. Emal, R. Jeffrey Neitz, William R. Roush, and Philip J. Rosenthal
Antimicrob. Agents Chemother. January 2003 47: 154-160;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Susceptibilities to and Bactericidal Activities of Garenoxacin (BMS-284756) and Other Antimicrobial Agents against Human Mycoplasmas and Ureaplasmas
Ken B. Waites, Donna M. Crabb, Xue Bing, and Lynn B. Duffy
Antimicrob. Agents Chemother. January 2003 47: 161-165;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activities of Cethromycin (ABT-773), a New Ketolide, against Streptococcus pneumoniae Strains That Are Not Susceptible to Penicillin or Macrolides
Edward O. Mason, Jr., Linda B. Lamberth, Ellen R. Wald, John S. Bradley, William J. Barson, and Sheldon L. Kaplan
Antimicrob. Agents Chemother. January 2003 47: 166-169;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Simple In Vitro Assay for Determining the Sensitivity of Plasmodium vivax Isolates from Fresh Human Blood to Antimalarials in Areas where P. vivax Is Endemic
Bruce M. Russell, Rachanee Udomsangpetch, Karl H. Rieckmann, Barbara M. Kotecka, Russell E. Coleman, and Jetsumon Sattabongkot
Antimicrob. Agents Chemother. January 2003 47: 170-173;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Worldwide Antimicrobial Susceptibility Patterns and Pharmacodynamic Comparisons of Gatifloxacin and Levofloxacin against Streptococcus pneumoniae: Report from the Antimicrobial Resistance Rate Epidemiology Study Team
Ronald N. Jones, Christopher M. Rubino, Sujata M. Bhavnani, and Paul G. Ambrose
Antimicrob. Agents Chemother. January 2003 47: 292-296;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

A Type II Pathway for Fatty Acid Biosynthesis Presents Drug Targets in Plasmodium falciparum
Ross F. Waller, Stuart A. Ralph, Michael B. Reed, Vanessa Su, James D. Douglas, David E. Minnikin, Alan F. Cowman, Gurdyal S. Besra, and Geoffrey I. McFadden
Antimicrob. Agents Chemother. January 2003 47: 297-301;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

High-Throughput Growth Assay for Toxoplasma gondii Using Yellow Fluorescent Protein
Marc-Jan Gubbels, Catherine Li, and Boris Striepen
Antimicrob. Agents Chemother. January 2003 47: 309-316;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activities of Daptomycin, Vancomycin, Quinupristin- Dalfopristin, Linezolid, and Five Other Antimicrobials against 307 Gram-Positive Anaerobic and 31 Corynebacterium Clinical Isolates
Ellie J. C. Goldstein, Diane M. Citron, C. Vreni Merriam, Yumi A. Warren, Kerrin L. Tyrrell, and Helen T. Fernandez
Antimicrob. Agents Chemother. January 2003 47: 337-341;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Comparison of Linezolid Activities under Aerobic and Anaerobic Conditions against Methicillin-Resistant Staphylococcus aureus and Vancomycin-Resistant Enterococcus faecium
Brent W. Gunderson, Khalid H. Ibrahim, Charles A. Peloquin, Laurie B. Hovde, and John C. Rotschafer
Antimicrob. Agents Chemother. January 2003 47: 398-399;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Activities of the Glycylcycline Tigecycline (GAR-936) against 1,924 Recent European Clinical Bacterial Isolates
D. Milatovic, F.-J. Schmitz, J. Verhoef, and A. C. Fluit
Antimicrob. Agents Chemother. January 2003 47: 400-404;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Activities of HMR 3787 and RU 64399 Compared with Those of Four Other Agents against Haemophilus influenzae and Haemophilus parainfluenzae
Bülent Bozdogan, Catherine Clark, Andre Bryskier, Michael R. Jacobs, and Peter C. Appelbaum
Antimicrob. Agents Chemother. January 2003 47: 405-407;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Flow Cytometric Assessment of Susceptibilities of Streptococcus pyogenes to Erythromycin and Rokitamycin
Pier Carlo Braga, Cinzia Bovio, Maria Culici, and Monica Dal Sasso
Antimicrob. Agents Chemother. January 2003 47: 408-412;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antibiotic Susceptibilities of Anaplasma (Ehrlichia) phagocytophilum Strains from Various Geographic Areas in the United States
Max Maurin, Johan S. Bakken, and J. Stephen Dumler
Antimicrob. Agents Chemother. January 2003 47: 413-415;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activities of Linezolid against Clinical Isolates of Mycobacterium tuberculosis That Are Susceptible or Resistant to First-Line Antituberculous Drugs
Luis Alcalá, María Jesús Ruiz-Serrano, Cristina Pérez-Fernández Turégano, Darío García de Viedma, Marisol Díaz-Infantes, Mercedes Marín-Arriaza, and Emilio Bouza
Antimicrob. Agents Chemother. January 2003 47: 416-417;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Bactericidal Activities of Linezolid in Combination with Vancomycin, Gentamicin, Ciprofloxacin, Fusidic Acid, and Rifampin against Staphylococcus aureus
Patrick Grohs, Marie-Dominique Kitzis, and Laurent Gutmann
Antimicrob. Agents Chemother. January 2003 47: 418-420;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Experimental Therapeutics:

In Vivo Antibacterial Activity of RWJ-54428, a New Cephalosporin with Activity against Gram-Positive Bacteria
David C. Griffith, Laurie Harford, Robert Williams, Ving J. Lee, and Michael N. Dudley
Antimicrob. Agents Chemother. January 2003 47: 43-47;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Modeling of Transfer Kinetics at the Serum-Cerebrospinal Fluid Barrier in Rabbits with Experimental Meningitis: Application to Grepafloxacin
Marc Pfister, Liping Zhang, Margareta Hammarlund-Udenaes, Lewis B. Sheiner, Cynthia M. Gerber, Martin G. Täuber, and Philippe Cottagnoud
Antimicrob. Agents Chemother. January 2003 47: 138-143;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Garenoxacin (BMS-284756) and Moxifloxacin in Experimental Meningitis Caused by Vancomycin-Tolerant Pneumococci
Violeta Rodriguez-Cerrato, Cindy C. McCoig, Jesus Saavedra, Tess Barton, Ian C. Michelow, Robert D. Hardy, Karen Bowlware, Janie Iglehart, Kathy Katz, and George H. McCracken, Jr
Antimicrob. Agents Chemother. January 2003 47: 211-215;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Activity and Diffusion of Tigecycline (GAR-936) in Experimental Enterococcal Endocarditis
Agnès Lefort, Matthieu Lafaurie, Laurent Massias, Yolande Petegnief, Azzam Saleh-Mghir, Claudette Muller-Serieys, Dominique Le Guludec, and Bruno Fantin
Antimicrob. Agents Chemother. January 2003 47: 216-222;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Chemotherapy with Benznidazole and Itraconazole for Mice Infected with Different Trypanosoma cruzi Clonal Genotypes
Max Jean de Ornelas Toledo, Maria Terezinha Bahia, Cláudia M. Carneiro, Olindo Assis Martins-Filho, Michel Tibayrenc, Christian Barnabé, Washington Luis Tafuri, and Marta de Lana
Antimicrob. Agents Chemother. January 2003 47: 223-230;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Activities of Moxifloxacin Alone and in Combination with Other Antimicrobial Agents against Multidrug-Resistant Mycobacterium tuberculosis Infection in BALB/c Mice
Lanfranco Fattorini, Dejiang Tan, Elisabetta Iona, Maurizio Mattei, Federico Giannoni, Lara Brunori, Simona Recchia, and Graziella Orefici
Antimicrob. Agents Chemother. January 2003 47: 360-362;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Biologic Response Modifiers:

Fourteen-Member Macrolides Promote the Phosphatidylserine Receptor-Dependent Phagocytosis of Apoptotic Neutrophils by Alveolar Macrophages
Takeshi Yamaryo, Kazunori Oishi, Hiroyuki Yoshimine, Yoshiko Tsuchihashi, Kouji Matsushima, and Tsuyoshi Nagatake
Antimicrob. Agents Chemother. January 2003 47: 48-53;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Clindamycin Modulates Inflammatory-Cytokine Induction in Lipopolysaccharide-Stimulated Mouse Peritoneal Macrophages
Tetsuji Nakano, Kazufumi Hiramatsu, Kenji Kishi, Norio Hirata, Jun-ichi Kadota, and Masaru Nasu
Antimicrob. Agents Chemother. January 2003 47: 363-367;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antiviral Agents:

Correlation of Phenotypic Zidovudine Resistance with Mutational Patterns in the Reverse Transcriptase of Human Immunodeficiency Virus Type 1: Interpretation of Established Mutations and Characterization of New Polymorphisms at Codons 208, 211, and 214
Martin Stürmer, Schlomo Staszewski, Hans-Wilhelm Doerr, Brendan Larder, Stuart Bloor, and Kurt Hertogs
Antimicrob. Agents Chemother. January 2003 47: 54-61;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Ribavirin Quantification in Combination Treatment of Chronic Hepatitis C
Sylvie Larrat, Françoise Stanke-Labesque, Agnès Plages, Jean-Pierre Zarski, Germain Bessard, and Claude Souvignet
Antimicrob. Agents Chemother. January 2003 47: 124-129;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Population Pharmacokinetics and Pharmacodynamics of Efavirenz, Nelfinavir, and Indinavir: Adult AIDS Clinical Trial Group Study 398
Marc Pfister, Line Labbé, Scott M. Hammer, John Mellors, Kara K. Bennett, Susan Rosenkranz, and Lewis B. Sheiner
Antimicrob. Agents Chemother. January 2003 47: 130-137;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Ribonucleoside Analogue That Blocks Replication of Bovine Viral Diarrhea and Hepatitis C Viruses in Culture
Lieven J. Stuyver, Tony Whitaker, Tamara R. McBrayer, Brenda I. Hernandez-Santiago, Stefania Lostia, Phillip M. Tharnish, Mangala Ramesh, Chung K. Chu, Robert Jordan, Junxing Shi, Suguna Rachakonda, Kyoichi A. Watanabe, Michael J. Otto, and Raymond F. Schinazi
Antimicrob. Agents Chemother. January 2003 47: 244-254;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Enzymatic Assay for Measurement of Intracellular DXG Triphosphate Concentrations in Peripheral Blood Mononuclear Cells from Human Immunodeficiency Virus Type 1-Infected Patients
Stephen Kewn, Laurene H. Wang, Patrick G. Hoggard, Franck Rousseau, Robert Hart, John P. MacNeela, Saye H. Khoo, and David J. Back
Antimicrob. Agents Chemother. January 2003 47: 255-261;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Comparison of Anti-Hepatitis B Virus Activities of Lamivudine and Clevudine by a Quantitative Assay
Ayman M. Abdelhamed, Colleen M. Kelley, Thomas G. Miller, Phillip A. Furman, Edward E. Cable, and Harriet C. Isom
Antimicrob. Agents Chemother. January 2003 47: 324-336;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pharmacokinetic-Pharmacodynamic Analysis of Lopinavir-Ritonavir in Combination with Efavirenz and Two Nucleoside Reverse Transcriptase Inhibitors in Extensively Pretreated Human Immunodeficiency Virus-Infected Patients
Ann Hsu, Jeffrey Isaacson, Scott Brun, Barry Bernstein, Wayne Lam, Richard Bertz, Cheryl Foit, Karen Rynkiewicz, Bruce Richards, Martin King, Richard Rode, Dale J. Kempf, G. Richard Granneman, and Eugene Sun
Antimicrob. Agents Chemother. January 2003 47: 350-359;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Activation and Deactivation of a Broad-Spectrum Antiviral Drug by a Single Enzyme: Adenosine Deaminase Catalyzes Two Consecutive Deamination Reactions
Jim Zhen Wu, Heli Walker, Johnson Y. N. Lau, and Zhi Hong
Antimicrob. Agents Chemother. January 2003 47: 426-431;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pharmacology:

Steady-State Pharmacokinetics of Amprenavir Coadministered with Ritonavir in Human Immunodeficiency Virus Type 1-Infected Patients
Cecile Goujard, Isabelle Vincent, Jean-Luc Meynard, Nathalie Choudet, Diane Bollens, Cyril Rousseau, Didier Demarles, Catherine Gillotin, Roselyne Bidault, and Anne-Marie Taburet
Antimicrob. Agents Chemother. January 2003 47: 118-123;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Discrepancies between Protease Inhibitor Concentrations and Viral Load in Reservoirs and Sanctuary Sites in Human Immunodeficiency Virus-Infected Patients
Caroline Solas, Alain Lafeuillade, Philippe Halfon, Stéphane Chadapaud, Gilles Hittinger, and Bruno Lacarelle
Antimicrob. Agents Chemother. January 2003 47: 238-243;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Penetration of Dihydroartemisinin into Cerebrospinal Fluid after Administration of Intravenous Artesunate in Severe Falciparum Malaria
Timothy M. E. Davis, Tran Quang Binh, Kenneth F. Ilett, Kevin T. Batty, Hoang Lan Phuöng, Gregory M. Chiswell, Vu Duong Bich Phuong, and Cindy Agus
Antimicrob. Agents Chemother. January 2003 47: 368-370;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Penetration of Fosfomycin into Inflammatory Lesions in Patients with Cellulitis or Diabetic Foot Syndrome
F. J. Legat, A. Maier, P. Dittrich, P. Zenahlik, T. Kern, S. Nuhsbaumer, M. Frossard, W. Salmhofer, H. Kerl, and M. Müller
Antimicrob. Agents Chemother. January 2003 47: 371-374;
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Clinical Therapeutics:

Combination of Drug Level Measurement and Parasite Genotyping Data for Improved Assessment of Amodiaquine and Sulfadoxine-Pyrimethamine Efficacies in Treating Plasmodium falciparum Malaria in Gabonese Children
Agnès Aubouy, Mohamed Bakary, Annick Keundjian, Bernard Mbomat, Jean Ruffin Makita, Florence Migot-Nabias, Michel Cot, Jacques Le Bras, and Philippe Deloron
Antimicrob. Agents Chemother. January 2003 47: 231-237;
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Letters:

Mutant Prevention Concentration of Gemifloxacin for Clinical Isolates of Streptococcus pneumoniae
Glen T. Hansen, Kelli Metzler, Karl Drlica, and Joseph M. Blondeau
Antimicrob. Agents Chemother. January 2003 47: 440-441;
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High Impact of an Expanded Restriction Fragment Length Polymorphism Assay on Detection of Ganciclovir-Resistant UL97 Mutants of Human Cytomegalovirus
Tobias Eckle, Gerhard Jahn, and Klaus Hamprecht
Antimicrob. Agents Chemother. January 2003 47: 442-443;
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Moxifloxacin for Community-Acquired Pneumonia
Bart J. A. Rijnders, Roger Finch, Dirk Schürmann, Rolf Kubin, Owen Collins, Julie McGivern, Jose L. Izquierdo, F. William Ogundare, and Gert Höffken
Antimicrob. Agents Chemother. January 2003 47: 444-445;
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Use of Macrolides for Q Fever
Didier Raoult
Antimicrob. Agents Chemother. January 2003 47: 446
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