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Mechanisms of Resistance:

Laura Y. Young, Christina M. Hull, and Joseph Heitman

Disruption of Ergosterol Biosynthesis Confers Resistance to Amphotericin B in Candida lusitaniae
Antimicrob. Agents Chemother. 2003 47: 2717-2724. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Philip Hill, Jacques Kessl, Nicholas Fisher, Steven Meshnick, Bernard L. Trumpower, and Brigitte Meunier

Recapitulation in Saccharomyces cerevisiae of Cytochrome b Mutations Conferring Resistance to Atovaquone in Pneumocystis jiroveci
Antimicrob. Agents Chemother. 2003 47: 2725-2731. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

John Wain, L. T. Diem Nga, Claire Kidgell, Keith James, Sarah Fortune, To Song Diep, Tahir Ali, Peadar Ó Gaora, Christopher Parry, Julian Parkhill, Jeremy Farrar, Nicholas J. White, and Gordon Dougan

Molecular Analysis of incHI1 Antimicrobial Resistance Plasmids from Salmonella Serovar Typhi Strains Associated with Typhoid Fever
Antimicrob. Agents Chemother. 2003 47: 2732-2739. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

T. Schneiders, S. G. B. Amyes, and S. B. Levy

Role of AcrR and RamA in Fluoroquinolone Resistance in Clinical Klebsiella pneumoniae Isolates from Singapore
Antimicrob. Agents Chemother. 2003 47: 2831-2837. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mário Correia, Filipa Boavida, Filipa Grosso, M. J. Salgado, L. M. Lito, J. Melo Cristino, Sónia Mendo, and Aida Duarte

Molecular Characterization of a New Class 3 Integron in Klebsiella pneumoniae
Antimicrob. Agents Chemother. 2003 47: 2838-2843. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Eleonora Giovanetti, Andrea Brenciani, Remo Lupidi, Marilyn C. Roberts, and Pietro E. Varaldo

Presence of the tet(O) Gene in Erythromycin- and Tetracycline-Resistant Strains of Streptococcus pyogenes and Linkage with either the mef(A) or the erm(A) Gene
Antimicrob. Agents Chemother. 2003 47: 2844-2849. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Annika I. Nilsson, Otto G. Berg, Olle Aspevall, Gunnar Kahlmeter, and Dan I. Andersson

Biological Costs and Mechanisms of Fosfomycin Resistance in Escherichia coli
Antimicrob. Agents Chemother. 2003 47: 2850-2858. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mark A. Toleman, Kenneth Rolston, Ronald N. Jones, and Timothy R. Walsh

Molecular and Biochemical Characterization of OXA-45, an Extended-Spectrum Class 2d' ß-Lactamase in Pseudomonas aeruginosa
Antimicrob. Agents Chemother. 2003 47: 2859-2863. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

M. Quinteros, M. Radice, N. Gardella, M. M. Rodriguez, N. Costa, D. Korbenfeld, E. Couto, and G. Gutkind

Extended-Spectrum ß-Lactamases in Enterobacteriaceae in Buenos Aires, Argentina, Public Hospitals
Antimicrob. Agents Chemother. 2003 47: 2864-2867. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jacob Bøsling, Susan M. Poulsen, Birte Vester, and Katherine S. Long

Resistance to the Peptidyl Transferase Inhibitor Tiamulin Caused by Mutation of Ribosomal Protein L3
Antimicrob. Agents Chemother. 2003 47: 2892-2896. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ken J. Dery, Britta Søballe, Mavee S. L. Witherspoon, Duyen Bui, Robert Koch, David J. Sherratt, and Marcelo E. Tolmasky

The Aminoglycoside 6'-N-Acetyltransferase Type Ib Encoded by Tn1331 Is Evenly Distributed within the Cell's Cytoplasm
Antimicrob. Agents Chemother. 2003 47: 2897-2902. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sophie A. Granier, Véronique Leflon-Guibout, Fred W. Goldstein, and Marie-Hélène Nicolas-Chanoine

New Klebsiella oxytoca ß-Lactamase Genes bla_OXY-3 and bla_OXY-4 and a Third Genetic Group of K. oxytoca Based on bla_OXY-3
Antimicrob. Agents Chemother. 2003 47: 2922-2928. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Laurent Poirel, Jean-Winoc Decousser, and Patrice Nordmann

Insertion Sequence ISEcp1B Is Involved in Expression and Mobilization of a bla_CTX-M ß-Lactamase Gene
Antimicrob. Agents Chemother. 2003 47: 2938-2945. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Corinna Kehrenberg, Nga Thi Thu Tham, and Stefan Schwarz

New Plasmid-Borne Antibiotic Resistance Gene Cluster in Pasteurella multocida
Antimicrob. Agents Chemother. 2003 47: 2978-2980. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hiroshi Kurokawa, Naohiro Shibata, Yohei Doi, Keigo Shibayama, Kazunari Kamachi, Tetsuya Yagi, and Yoshichika Arakawa

A New TEM-Derived Extended-Spectrum ß-Lactamase (TEM-91) with an R164C Substitution at the -Loop Confers Ceftazidime Resistance
Antimicrob. Agents Chemother. 2003 47: 2981-2983. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Monique M. Gerrits, Marco Berning, Arnoud H. M. Van Vliet, Ernst J. Kuipers, and Johannes G. Kusters

Effects of 16S rRNA Gene Mutations on Tetracycline Resistance in Helicobacter pylori
Antimicrob. Agents Chemother. 2003 47: 2984-2986. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hiroshi Sekiya, Takehiko Mima, Yuji Morita, Teruo Kuroda, Tohru Mizushima, and Tomofusa Tsuchiya

Functional Cloning and Characterization of a Multidrug Efflux Pump, MexHI-OpmD, from a Pseudomonas aeruginosa Mutant
Antimicrob. Agents Chemother. 2003 47: 2990-2992. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

C. Moubareck, N. Bourgeois, P. Courvalin, and F. Doucet-Populaire

Multiple Antibiotic Resistance Gene Transfer from Animal to Human Enterococci in the Digestive Tract of Gnotobiotic Mice
Antimicrob. Agents Chemother. 2003 47: 2993-2996. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kazuko Taniguchi, Tsuneko Ono, Keiji Murakami, Darija Viducic, Sizuo Kayama, Katsuhiko Hirota, Ken Nemoto, and Yoichiro Miyake

Novel Pseudomonas aeruginosa Gene That Suppresses Tolerance to Carbapenems
Antimicrob. Agents Chemother. 2003 47: 2997-3001. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kunihiko Nishino, Junko Yamada, Hidetada Hirakawa, Takahiro Hirata, and Akihito Yamaguchi

Roles of TolC-Dependent Multidrug Transporters of Escherichia coli in Resistance to ß-Lactams
Antimicrob. Agents Chemother. 2003 47: 3030-3033. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Experimental Therapeutics:

Nelly A. Kuklin, Gregory D. Pancari, Timothy W. Tobery, Leslie Cope, Jesse Jackson, Charles Gill, Karen Overbye, Kevin P. Francis, Jun Yu, Donna Montgomery, Annaliesa S. Anderson, William McClements, and Kathrin U. Jansen

Real-Time Monitoring of Bacterial Infection In Vivo: Development of Bioluminescent Staphylococcal Foreign-Body and Deep-Thigh-Wound Mouse Infection Models
Antimicrob. Agents Chemother. 2003 47: 2740-2748. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

F. Scaglione, J. W. Mouton, R. Mattina, and F. Fraschini

Pharmacodynamics of Levofloxacin and Ciprofloxacin in a Murine Pneumonia Model: Peak Concentration/MIC versus Area under the Curve/MIC Ratios
Antimicrob. Agents Chemother. 2003 47: 2749-2755. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Fu-Yu Chiang and Michael Climo

Efficacy of Linezolid Alone or in Combination with Vancomycin for Treatment of Experimental Endocarditis Due to Methicillin-Resistant Staphylococcus aureus
Antimicrob. Agents Chemother. 2003 47: 3002-3004. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Qurrat ul-Ain, Sadhna Sharma, and G. K. Khuller

Chemotherapeutic Potential of Orally Administered Poly(Lactide-Co-Glycolide) Microparticles Containing Isoniazid, Rifampin, and Pyrazinamide against Experimental Tuberculosis
Antimicrob. Agents Chemother. 2003 47: 3005-3007. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Clinical Therapeutics:

Eric Chamot, Emmanuelle Boffi El Amari, Peter Rohner, and Christian Van Delden

Effectiveness of Combination Antimicrobial Therapy for Pseudomonas aeruginosa Bacteremia
Antimicrob. Agents Chemother. 2003 47: 2756-2764. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sarah L. Batt, Bambos M. Charalambous, Anthony W. Solomon, Charles Knirsch, Patrick A. Massae, Salesia Safari, Noel E. Sam, Dean Everett, David C. W. Mabey, and Stephen H. Gillespie

Impact of Azithromycin Administration for Trachoma Control on the Carriage of Antibiotic-Resistant Streptococcus pneumoniae
Antimicrob. Agents Chemother. 2003 47: 2765-2769. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Dan C. Henry, Ernie Riffer, William N. Sokol, Naumann I. Chaudry, and Robert N. Swanson

Randomized Double-Blind Study Comparing 3- and 6-Day Regimens of Azithromycin with a 10-Day Amoxicillin-Clavulanate Regimen for Treatment of Acute Bacterial Sinusitis
Antimicrob. Agents Chemother. 2003 47: 2770-2774. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Peter W. Kim, Anthony D. Harris, Mary-Claire Roghmann, J. Glenn Morris, Jr., Arjun Strinivasan, and Eli N. Perencevich

Epidemiological Risk Factors for Isolation of Ceftriaxone-Resistant versus -Susceptible Citrobacter freundii in Hospitalized Patients
Antimicrob. Agents Chemother. 2003 47: 2882-2887. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Dianne J. Terlouw, Bernard L. Nahlen, Jeanne M. Courval, Simon K. Kariuki, Oren S. Rosenberg, Aggrey J. Oloo, Margarette S. Kolczak, William A. Hawley, Altaf A. Lal, and Feiko O. ter Kuile

Sulfadoxine-Pyrimethamine in Treatment of Malaria in Western Kenya: Increasing Resistance and Underdosing
Antimicrob. Agents Chemother. 2003 47: 2929-2932. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pharmacology:

Michael E. Brier, Dennis J. Stalker, George R. Aronoff, Donald H. Batts, Kristi K. Ryan, Margaret O'Grady, Nancy K. Hopkins, and Gail L. Jungbluth

Pharmacokinetics of Linezolid in Subjects with Renal Dysfunction
Antimicrob. Agents Chemother. 2003 47: 2775-2780. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

J. Nieto, J. Alvar, A. B. Mullen, K. C. Carter, C. Rodríguez, M. I. San Andrés, M. D. San Andrés, A. J. Baillie, and F. González

Pharmacokinetics, Toxicities, and Efficacies of Sodium Stibogluconate Formulations after Intravenous Administration in Animals
Antimicrob. Agents Chemother. 2003 47: 2781-2787. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Rachel Courtney, Sudhakar Pai, Mark Laughlin, Josephine Lim, and Vijay Batra

Pharmacokinetics, Safety, and Tolerability of Oral Posaconazole Administered in Single and Multiple Doses in Healthy Adults
Antimicrob. Agents Chemother. 2003 47: 2788-2795. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Vincent H. Tam, Sandra L. Preston, and G. L. Drusano

Optimal Sampling Schedule Design for Populations of Patients
Antimicrob. Agents Chemother. 2003 47: 2888-2891. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

F. Scaglione, D. Caronzolo, J. P. Pintucci, and F. Fraschini

Measurement of Cefaclor and Amoxicillin-Clavulanic Acid Levels in Middle-Ear Fluid in Patients with Acute Otitis Media
Antimicrob. Agents Chemother. 2003 47: 2987-2989. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Biologic Response Modifiers:

Kishor M. Wasan, Olena Sivak, Richard A. Cote, Aaron I. MacInnes, Kathy D. Boulanger, Melvyn Lynn, William J. Christ, Lynn D. Hawkins, and Daniel P. Rossignol

Association of the Endotoxin Antagonist E5564 with High-Density Lipoproteins In Vitro: Dependence on Low-Density and Triglyceride-Rich Lipoprotein Concentrations
Antimicrob. Agents Chemother. 2003 47: 2796-2803. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Susceptibility:

David M. Hoover, Zhibin Wu, Kenneth Tucker, Wuyuan Lu, and Jacek Lubkowski

Antimicrobial Characterization of Human ß-Defensin 3 Derivatives
Antimicrob. Agents Chemother. 2003 47: 2804-2809. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Rea Krausse and Uwe Ullmann

In Vitro Activities of New Fluoroquinolones against Campylobacter jejuni and Campylobacter coli Isolates Obtained from Humans in 1980 to 1982 and 1997 to 2001
Antimicrob. Agents Chemother. 2003 47: 2946-2950. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Annika Krüüner, Pontus Jureen, Klavdia Levina, Solomon Ghebremichael, and Sven Hoffner

Discordant Resistance to Kanamycin and Amikacin in Drug-Resistant Mycobacterium tuberculosis
Antimicrob. Agents Chemother. 2003 47: 2971-2973. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

M. I. Restrepo, J. A. Velez, M. L. McElmeel, C. G. Whitney, and J. H. Jorgensen

Activity of Daptomycin against Recent North American Isolates of Streptococcus pneumoniae
Antimicrob. Agents Chemother. 2003 47: 2974-2977. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ellie J. C. Goldstein, Diane M. Citron, C. Vreni Merriam, Yumi A. Warren, Kerin L. Tyrrell, and Helen T. Fernandez

In Vitro Activities of ABT-492, a New Fluoroquinolone, against 155 Aerobic and 171 Anaerobic Pathogens Isolated from Antral Sinus Puncture Specimens from Patients with Sinusitis
Antimicrob. Agents Chemother. 2003 47: 3008-3011. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

G. A. Pankuch, M. R. Jacobs, and P. C. Appelbaum

Postantibiotic Effects of Daptomycin against 14 Staphylococcal and Pneumococcal Clinical Isolates
Antimicrob. Agents Chemother. 2003 47: 3012-3014. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Elizabeth Nenortas, Tomasz Kulikowicz, Christian Burri, and Theresa A. Shapiro

Antitrypanosomal Activities of Fluoroquinolones with Pyrrolidinyl Substitutions
Antimicrob. Agents Chemother. 2003 47: 3015-3017. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Zekaver Odabasi, Victor Paetznick, Beth P. Goldstein, John H. Rex, and Luis Ostrosky-Zeichner

Disk Diffusion-Based Methods for Determining Candida parapsilosis Susceptibility to Anidulafungin
Antimicrob. Agents Chemother. 2003 47: 3018-3020. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pascale Bemer, Marie-Emmanuelle Juvin, Andre Bryskier, and Henri Drugeon

In Vitro Activities of a New Lipopeptide, HMR 1043, against Susceptible and Resistant Gram-Positive Isolates
Antimicrob. Agents Chemother. 2003 47: 3025-3029. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Antiviral Agents:

Xin Chen, Lu Yang, Ning Zhang, Jim A. Turpin, Robert W. Buckheit, Clay Osterling, Joost J. Oppenheim, and O. M. Zack Howard

Shikonin, a Component of Chinese Herbal Medicine, Inhibits Chemokine Receptor Function and Suppresses Human Immunodeficiency Virus Type 1
Antimicrob. Agents Chemother. 2003 47: 2810-2816. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Luis M. F. Gonzalez, Rodrigo M. Brindeiro, Michelle Tarin, Alexandre Calazans, Marcelo A. Soares, Sharon Cassol, and Amilcar Tanuri

In Vitro Hypersusceptibility of Human Immunodeficiency Virus Type 1 Subtype C Protease to Lopinavir
Antimicrob. Agents Chemother. 2003 47: 2817-2822. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Masako Unoshima, Hideo Iwasaka, Junko Eto, Yoshiko Takita-Sonoda, Takayuki Noguchi, and Akira Nishizono

Antiviral Effects of Geranylgeranylacetone: Enhancement of MxA Expression and Phosphorylation of PKR during Influenza Virus Infection
Antimicrob. Agents Chemother. 2003 47: 2914-2921. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Chad J. Roy, Robert Baker, Kenneth Washburn, and Mike Bray

Aerosolized Cidofovir Is Retained in the Respiratory Tract and Protects Mice against Intranasal Cowpox Virus Challenge
Antimicrob. Agents Chemother. 2003 47: 2933-2937. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Miguel Stevens, Christophe Pannecouque, Erik De Clercq, and Jan Balzarini

Inhibition of Human Immunodeficiency Virus by a New Class of Pyridine Oxide Derivatives
Antimicrob. Agents Chemother. 2003 47: 2951-2957. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Muriel Macé, Chaysavanh Manichanh, Pascale Bonnafous, Stéphanie Précigout, David Boutolleau, Agnès Gautheret-Dejean, and Henri Agut

Real-Time PCR as a Versatile Tool for Investigating the Susceptibility of Human Herpesvirus 6 to Antiviral Agents
Antimicrob. Agents Chemother. 2003 47: 3021-3024. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Chemistry; Biosynthesis:

Michael G. Thomas, Yolande A. Chan, and Sarah G. Ozanick

Deciphering Tuberactinomycin Biosynthesis: Isolation, Sequencing, and Annotation of the Viomycin Biosynthetic Gene Cluster
Antimicrob. Agents Chemother. 2003 47: 2823-2830. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Dmitri E. Fomenko, Anastazia Z. Metlitskaya, Jean Péduzzi, Christophe Goulard, Genrikh S. Katrukha, Leonid V. Gening, Sylvie Rebuffat, and Inessa A. Khmel

Microcin C51 Plasmid Genes: Possible Source of Horizontal Gene Transfer
Antimicrob. Agents Chemother. 2003 47: 2868-2874. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Action:

R. Edward Benson, Elizabeth B. Gottlin, Dale J. Christensen, and Paul T. Hamilton

Intracellular Expression of Peptide Fusions for Demonstration of Protein Essentiality in Bacteria
Antimicrob. Agents Chemother. 2003 47: 2875-2881. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Joanna C. Betts, Alistair McLaren, Mark G. Lennon, Fiona M. Kelly, Pauline T. Lukey, Steve J. Blakemore, and Ken Duncan

Signature Gene Expression Profiles Discriminate between Isoniazid-, Thiolactomycin-, and Triclosan-Treated Mycobacterium tuberculosis
Antimicrob. Agents Chemother. 2003 47: 2903-2913. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

C. Aumeran, C. Chanal, R. Labia, D. Sirot, J. Sirot, and R. Bonnet

Effects of Ser130Gly and Asp240Lys Substitutions in Extended-Spectrum ß-Lactamase CTX-M-9
Antimicrob. Agents Chemother. 2003 47: 2958-2961. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Nick D. Allan and Terry J. Beveridge

Gentamicin Delivery to Burkholderia cepacia Group IIIa Strains via Membrane Vesicles from Pseudomonas aeruginosa PAO1
Antimicrob. Agents Chemother. 2003 47: 2962-2965. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Gonzalo Visbal, Alvaro Alvarez, Belisario Moreno, and Gioconda San-Blas

S-Adenosyl-L-Methionine Inhibitors ²⁴-Sterol Methyltransferase and ²⁴⁽²⁸⁾-Sterol Methylreductase as Possible Agents against Paracoccidioides brasiliensis
Antimicrob. Agents Chemother. 2003 47: 2966-2970. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Letters:

Christian G. Giske, Margareta Rylander, and Göran Kronvall

VIM-4 in a Carbapenem-Resistant Strain of Pseudomonas aeruginosa Isolated in Sweden
Antimicrob. Agents Chemother. 2003 47: 3034-3035. [Full Text] [PDF] [Reprints and Permissions]  

Errata:

Njinkeng Joseph Nkemngu, Vera Rosenkranz, Michael Wink, and Dietmar Steverding

Antitrypanosomal Activities of Proteasome Inhibitors
Antimicrob. Agents Chemother. 2003 47: 3036. [Full Text] [PDF] [Reprints and Permissions]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.