To see an article, click its [Full Text], [Abstract] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

Mechanisms of Resistance:

Thomas Gruger, John L. Nitiss, Anthony Maxwell, E. Lynn Zechiedrich, Peter Heisig, Siegfried Seeber, Yves Pommier, and Dirk Strumberg

A Mutation in Escherichia coli DNA Gyrase Conferring Quinolone Resistance Results in Sensitivity to Drugs Targeting Eukaryotic Topoisomerase II
Antimicrob. Agents Chemother. 2004 48: 4495-4504. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Chia-Geun Chen, Yun-Liang Yang, Hsin-I Shih, Chia-Li Su, and Hsiu-Jung Lo

CaNdt80 Is Involved in Drug Resistance in Candida albicans by Regulating CDR1
Antimicrob. Agents Chemother. 2004 48: 4505-4512. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Laurent Poirel, Hedi Mammeri, and Patrice Nordmann

TEM-121, a Novel Complex Mutant of TEM-Type ß-Lactamase from Enterobacter aerogenes
Antimicrob. Agents Chemother. 2004 48: 4528-4531. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Lucia Pallecchi, Monica Malossi, Antonia Mantella, Eduardo Gotuzzo, Christian Trigoso, Alessandro Bartoloni, Franco Paradisi, Göran Kronvall, and Gian Maria Rossolini

Detection of CTX-M-Type ß-Lactamase Genes in Fecal Escherichia coli Isolates from Healthy Children in Bolivia and Peru
Antimicrob. Agents Chemother. 2004 48: 4556-4561. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Anatoly Severin, Shang Wei Wu, Keiko Tabei, and Alexander Tomasz

Penicillin-Binding Protein 2 Is Essential for Expression of High-Level Vancomycin Resistance and Cell Wall Synthesis in Vancomycin- Resistant Staphylococcus aureus Carrying the Enterococcal vanA Gene Complex
Antimicrob. Agents Chemother. 2004 48: 4566-4573. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mayumi Matsuoka, Mitsuo Narita, Norio Okazaki, Hitomi Ohya, Tsutomu Yamazaki, Kazunobu Ouchi, Isao Suzuki, Tomoaki Andoh, Tsuyoshi Kenri, Yuko Sasaki, Atsuko Horino, Miharu Shintani, Yoshichika Arakawa, and Tsuguo Sasaki

Characterization and Molecular Analysis of Macrolide-Resistant Mycoplasma pneumoniae Clinical Isolates Obtained in Japan
Antimicrob. Agents Chemother. 2004 48: 4624-4630. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Esther W. Barrow, Philip C. Bourne, and William W. Barrow

Functional Cloning of Bacillus anthracis Dihydrofolate Reductase and Confirmation of Natural Resistance to Trimethoprim
Antimicrob. Agents Chemother. 2004 48: 4643-4649. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mariana Castanheira, Mark A. Toleman, Ronald N. Jones, Franz J. Schmidt, and Timothy R. Walsh

Molecular Characterization of a ß-Lactamase Gene, bla_GIM-1, Encoding a New Subclass of Metallo-ß-Lactamase
Antimicrob. Agents Chemother. 2004 48: 4654-4661. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Magdalena Sieprawska-Lupa, Piotr Mydel, Katarzyna Krawczyk, Kinga Wójcik, Magdalena Puklo, Boguslaw Lupa, Piotr Suder, Jerzy Silberring, Matthew Reed, Jan Pohl, William Shafer, Fionnuala McAleese, Timothy Foster, Jim Travis, and Jan Potempa

Degradation of Human Antimicrobial Peptide LL-37 by Staphylococcus aureus-Derived Proteinases
Antimicrob. Agents Chemother. 2004 48: 4673-4679. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Rodrigo E. Mendes, Mark A. Toleman, Julival Ribeiro, Helio S. Sader, Ronald N. Jones, and Timothy R. Walsh

Integron Carrying a Novel Metallo-ß-Lactamase Gene, bla_IMP-16, and a Fused Form of Aminoglycoside-Resistant Gene aac(6')-30/aac(6')-Ib': Report from the SENTRY Antimicrobial Surveillance Program
Antimicrob. Agents Chemother. 2004 48: 4693-4702. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jeffrey J. Campion, Patrick J. McNamara, and Martin E. Evans

Evolution of Ciprofloxacin-Resistant Staphylococcus aureus in In Vitro Pharmacokinetic Environments
Antimicrob. Agents Chemother. 2004 48: 4733-4744. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Bülent Bozdogan, Lois Ednie, Kim Credito, Klaudia Kosowska, and Peter C. Appelbaum

Derivatives of a Vancomycin-Resistant Staphylococcus aureus Strain Isolated at Hershey Medical Center
Antimicrob. Agents Chemother. 2004 48: 4762-4765. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jean-Denis Docquier, Teresa Lopizzo, Sabrina Liberatori, Manuela Prenna, Maria Cristina Thaller, Jean-Marie Frère, and Gian Maria Rossolini

Biochemical Characterization of the THIN-B Metallo-ß-Lactamase of Janthinobacterium lividum
Antimicrob. Agents Chemother. 2004 48: 4778-4783. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Neil Woodford, Philip M. Tierno, Jr., Katherine Young, Luke Tysall, Marie-France I. Palepou, Elaina Ward, Ronald E. Painter, Deborah F. Suber, Daniel Shungu, Lynn L. Silver, Kenneth Inglima, John Kornblum, and David M. Livermore

Outbreak of Klebsiella pneumoniae Producing a New Carbapenem- Hydrolyzing Class A ß-Lactamase, KPC-3, in a New York Medical Center
Antimicrob. Agents Chemother. 2004 48: 4793-4799. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hiromi Nishi, Hitoshi Komatsuzawa, Tamaki Fujiwara, Nadine McCallum, and Motoyuki Sugai

Reduced Content of Lysyl-Phosphatidylglycerol in the Cytoplasmic Membrane Affects Susceptibility to Moenomycin, as Well as Vancomycin, Gentamicin, and Antimicrobial Peptides, in Staphylococcus aureus
Antimicrob. Agents Chemother. 2004 48: 4800-4807. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Craig J. Munday, David A. Boyd, Nigel Brenwald, Mark Miller, Jennifer M. Andrews, Richard Wise, Michael R. Mulvey, and Peter M. Hawkey

Molecular and Kinetic Comparison of the Novel Extended-Spectrum ß-Lactamases CTX-M-25 and CTX-M-26
Antimicrob. Agents Chemother. 2004 48: 4829-4834. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sandhya Ramanathan-Girish, Juliet McColm, John M. Clements, Phil Taupin, Sue Barrowcliffe, John Hevizi, Sharon Safrin, Clive Moore, Gary Patou, Heinz Moser, Alison Gadd, Ute Hoch, Vernon Jiang, Denene Lofland, and Kirk W. Johnson

Pharmacokinetics in Animals and Humans of a First-in-Class Peptide Deformylase Inhibitor
Antimicrob. Agents Chemother. 2004 48: 4835-4842. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Yahua Chen, Fred C. Tenover, and Theresa M. Koehler

ß-Lactamase Gene Expression in a Penicillin-Resistant Bacillus anthracis Strain
Antimicrob. Agents Chemother. 2004 48: 4873-4877. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Lorena Abadía-Patiño, Keryn Christiansen, Jan Bell, Patrice Courvalin, and Bruno Périchon

VanE-Type Vancomycin-Resistant Enterococcus faecalis Clinical Isolates from Australia
Antimicrob. Agents Chemother. 2004 48: 4882-4885. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Rodrigo Alonso, Estibaliz Mateo, Cecilia Girbau, Estibaliz Churruca, Irati Martinez, and Aurora Fernández-Astorga

PCR-Restriction Fragment Length Polymorphism Assay for Detection of gyrA Mutations Associated with Fluoroquinolone Resistance in Campylobacter coli
Antimicrob. Agents Chemother. 2004 48: 4886-4888. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

María Margarita Rodríguez, Pablo Power, Marcela Radice, Carlos Vay, Angela Famiglietti, Moreno Galleni, Juan A. Ayala, and Gabriel Gutkind

Chromosome-Encoded CTX-M-3 from Kluyvera ascorbata: a Possible Origin of Plasmid-Borne CTX-M-1-Derived Cefotaximases
Antimicrob. Agents Chemother. 2004 48: 4895-4897. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

L. Guardabassi, H. Christensen, H. Hasman, and A. Dalsgaard

Members of the Genera Paenibacillus and Rhodococcus Harbor Genes Homologous to Enterococcal Glycopeptide Resistance Genes vanA and vanB
Antimicrob. Agents Chemother. 2004 48: 4915-4918. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Experimental Therapeutics:

Michael A. Pammit, Varija N. Budhavarapu, Erin K. Raulie, Karl E. Klose, Judy M. Teale, and Bernard P. Arulanandam

Intranasal Interleukin-12 Treatment Promotes Antimicrobial Clearance and Survival in Pulmonary Francisella tularensis subsp. novicida Infection
Antimicrob. Agents Chemother. 2004 48: 4513-4519. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Elizabeta Sauer, Melisa Merdanovic, Anne Price Mortimer, Gerhard Bringmann, and Joachim Reidl

PnuC and the Utilization of the Nicotinamide Riboside Analog 3-Aminopyridine in Haemophilus influenzae
Antimicrob. Agents Chemother. 2004 48: 4532-4541. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Boris V. Nikonenko, Rowena Samala, Leo Einck, and Carol A. Nacy

Rapid, Simple In Vivo Screen for New Drugs Active against Mycobacterium tuberculosis
Antimicrob. Agents Chemother. 2004 48: 4550-4555. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Evangelos J. Giamarellos-Bourboulis, Maria Mouktaroudi, Theodoros Adamis, Vassilios Koussoulas, Fotini Baziaka, Despina Perrea, Panayotis E. Karayannacos, and Helen Giamarellou

n-6 Polyunsaturated Fatty Acids Enhance the Activities of Ceftazidime and Amikacin in Experimental Sepsis Caused by Multidrug-Resistant Pseudomonas aeruginosa
Antimicrob. Agents Chemother. 2004 48: 4713-4717. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ildiko R. Dunay, Markus M. Heimesaat, Faris Nadiem Bushrab, Rainer H. Müller, Hartmut Stocker, Keikawus Arasteh, Michael Kurowski, Rudolf Fitzner, Klaus Borner, and Oliver Liesenfeld

Atovaquone Maintenance Therapy Prevents Reactivation of Toxoplasmic Encephalitis in a Murine Model of Reactivated Toxoplasmosis
Antimicrob. Agents Chemother. 2004 48: 4848-4854. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Dario Caronzolo, Valeria Lucini, Marilou Pannacci, Silvia Grosso, Federica Colleoni, Franco Fraschini, and Francesco Scaglione

Glucocorticoids Increase In Vitro and In Vivo Activities of Antibiotics against Chlamydophila pneumoniae
Antimicrob. Agents Chemother. 2004 48: 4878-4881. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Donna M. MacCallum and Frank C. Odds

Need for Early Antifungal Treatment Confirmed in Experimental Disseminated Candida albicans Infection
Antimicrob. Agents Chemother. 2004 48: 4911-4914. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Lenie Dijkshoorn, Carlo P. J. M. Brouwer, Sylvia J. P. Bogaards, Alexandr Nemec, Peterhans J. van den Broek, and Peter H. Nibbering

The Synthetic N-Terminal Peptide of Human Lactoferrin, hLF(1-11), Is Highly Effective against Experimental Infection Caused by Multidrug-Resistant Acinetobacter baumannii
Antimicrob. Agents Chemother. 2004 48: 4919-4921. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Susceptibility:

A. Mattana, G. Biancu, L. Alberti, A. Accardo, G. Delogu, P. L. Fiori, and P. Cappuccinelli

In Vitro Evaluation of the Effectiveness of the Macrolide Rokitamycin and Chlorpromazine against Acanthamoeba castellanii
Antimicrob. Agents Chemother. 2004 48: 4520-4527. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Simon J. F. Macdonald, Keith G. Watson, Rachel Cameron, David K. Chalmers, Derek A. Demaine, Rob J. Fenton, David Gower, J. Nicole Hamblin, Stephanie Hamilton, Graham J. Hart, Graham G. A. Inglis, Betty Jin, Haydn T. Jones, Darryl B. McConnell, Andy M. Mason, Van Nguyen, Ian J. Owens, Nigel Parry, Phillip A. Reece, Stephen E. Shanahan, Donna Smith, Wen-Yang Wu, and Simon P. Tucker

Potent and Long-Acting Dimeric Inhibitors of Influenza Virus Neuraminidase Are Effective at a Once-Weekly Dosing Regimen
Antimicrob. Agents Chemother. 2004 48: 4542-4549. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Fernando Alcaide, Laura Calatayud, Miguel Santín, and Rogelio Martín

Comparative In Vitro Activities of Linezolid, Telithromycin, Clarithromycin, Levofloxacin, Moxifloxacin, and Four Conventional Antimycobacterial Drugs against Mycobacterium kansasii
Antimicrob. Agents Chemother. 2004 48: 4562-4565. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

William J. Weiss, Peter J. Petersen, Timothy M. Murphy, LuAnna Tardio, Youjun Yang, Patricia A. Bradford, Aranapakam M. Venkatesan, Takao Abe, Takeshi Isoda, Ado Mihira, Hideki Ushirogochi, Tsuyoshi Takasake, Steve Projan, John O'Connell, and Tarek S. Mansour

In Vitro and In Vivo Activities of Novel 6-Methylidene Penems as ß-Lactamase Inhibitors
Antimicrob. Agents Chemother. 2004 48: 4589-4596. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Marilee D. Obritsch, Douglas N. Fish, Robert MacLaren, and Rose Jung

National Surveillance of Antimicrobial Resistance in Pseudomonas aeruginosa Isolates Obtained from Intensive Care Unit Patients from 1993 to 2002
Antimicrob. Agents Chemother. 2004 48: 4606-4610. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Marco R. Oggioni, Francesco Iannelli, Susanna Ricci, Damiana Chiavolini, Riccardo Parigi, Claudia Trappetti, Jean-Pierre Claverys, and Gianni Pozzi

Antibacterial Activity of a Competence-Stimulating Peptide in Experimental Sepsis Caused by Streptococcus pneumoniae
Antimicrob. Agents Chemother. 2004 48: 4725-4732. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

S. Branger, J. M. Rolain, and D. Raoult

Evaluation of Antibiotic Susceptibilities of Ehrlichia canis, Ehrlichia chaffeensis, and Anaplasma phagocytophilum by Real-Time PCR
Antimicrob. Agents Chemother. 2004 48: 4822-4828. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jung Mogg Kim, Joo Sung Kim, Hyun Chae Jung, Nayoung Kim, Young-Jeon Kim, and In Sung Song

Distribution of Antibiotic MICs for Helicobacter pylori Strains over a 16-Year Period in Patients from Seoul, South Korea
Antimicrob. Agents Chemother. 2004 48: 4843-4847. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Elena A. Govorkova, Hong-Bin Fang, Ming Tan, and Robert G. Webster

Neuraminidase Inhibitor-Rimantadine Combinations Exert Additive and Synergistic Anti-Influenza Virus Effects in MDCK Cells
Antimicrob. Agents Chemother. 2004 48: 4855-4863. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pio Maria Furneri, Anna Piperno, Antonella Sajia, and Giuseppe Bisignano

Antimycoplasmal Activity of Hydroxytyrosol
Antimicrob. Agents Chemother. 2004 48: 4892-4894. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sydney M. Finegold, Denise Molitoris, Marja-Liisa Vaisanen, Yuli Song, Chengxu Liu, and Mauricio Bolaños

In Vitro Activities of OPT-80 and Comparator Drugs against Intestinal Bacteria
Antimicrob. Agents Chemother. 2004 48: 4898-4902. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kristina Kadlec, Corinna Kehrenberg, Jürgen Wallmann, and Stefan Schwarz

Antimicrobial Susceptibility of Bordetella bronchiseptica Isolates from Porcine Respiratory Tract Infections
Antimicrob. Agents Chemother. 2004 48: 4903-4906. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

William J. Steinbach, Nina Singh, Jackie L. Miller, Daniel K. Benjamin, Jr., Wiley A. Schell, Joseph Heitman, and John R. Perfect

In Vitro Interactions between Antifungals and Immunosuppressants against Aspergillus fumigatus Isolates from Transplant and Nontransplant Patients
Antimicrob. Agents Chemother. 2004 48: 4922-4925. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jae-Hoon Song, Keiichi Hiramatsu, Ji Yoeun Suh, Kwan Soo Ko, Teruyo Ito, Maria Kapi, Sungmin Kiem, Yeon-Sook Kim, Won Sup Oh, Kyong Ran Peck, Nam Yong Lee and the Asian Network for Surveillance of Resistant Pathogens Study Group

Emergence in Asian Countries of Staphylococcus aureus with Reduced Susceptibility to Vancomycin
Antimicrob. Agents Chemother. 2004 48: 4926-4928. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Clinical Therapeutics:

Cheol-In Kang, Sung-Han Kim, Wan Beom Park, Ki-Deok Lee, Hong-Bin Kim, Eui-Chong Kim, Myoung-Don Oh, and Kang-Won Choe

Bloodstream Infections Due to Extended-Spectrum ß-Lactamase-Producing Escherichia coli and Klebsiella pneumoniae: Risk Factors for Mortality and Treatment Outcome, with Special Emphasis on Antimicrobial Therapy
Antimicrob. Agents Chemother. 2004 48: 4574-4581. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Didier Guillemot, Stephane Bonacorsi, John S. Blanchard, Philippe Weber, Sylvie Simon, Bruno Guesnon, Edouard Bingen, and Claude Carbon

Amoxicillin-Clavulanate Therapy Increases Childhood Nasal Colonization by Methicillin-Susceptible Staphylococcus aureus Strains Producing High Levels of Penicillinase
Antimicrob. Agents Chemother. 2004 48: 4618-4623. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kerry L. LaPlante and Michael J. Rybak

Impact of High-Inoculum Staphylococcus aureus on the Activities of Nafcillin, Vancomycin, Linezolid, and Daptomycin, Alone and in Combination with Gentamicin, in an In Vitro Pharmacodynamic Model
Antimicrob. Agents Chemother. 2004 48: 4665-4672. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Thomas P. Lodise, Jr., Ben Lomaestro, Keith A. Rodvold, Larry H. Danziger, and George L. Drusano

Pharmacodynamic Profiling of Piperacillin in the Presence of Tazobactam in Patients through the Use of Population Pharmacokinetic Models and Monte Carlo Simulation
Antimicrob. Agents Chemother. 2004 48: 4718-4724. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mahesh V. Patel, Noel J. De Souza, Shrikant V. Gupte, Mohammad A. Jafri, Sachin S. Bhagwat, Yati Chugh, Habil F. Khorakiwala, Michael R. Jacobs, and Peter C. Appelbaum

Antistaphylococcal Activity of WCK 771, a Tricyclic Fluoroquinolone, in Animal Infection Models
Antimicrob. Agents Chemother. 2004 48: 4754-4761. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Fritz Offner, Vladimir Krcmery, Marc Boogaerts, Chantal Doyen, Dan Engelhard, Patricia Ribaud, Catherine Cordonnier, Ben de Pauw, Simon Durrant, Jean-Pierre Marie, Philippe Moreau, Harry Guiot, George Samonis, Richard Sylvester, Raoul Herbrecht the EORTC Invasive Fungal Infections Group

Liposomal Nystatin in Patients with Invasive Aspergillosis Refractory to or Intolerant of Amphotericin B
Antimicrob. Agents Chemother. 2004 48: 4808-4812. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pharmacology:

Koichiro Watanabe, Kazunari Murakami, Ryugo Sato, Koji Kashimura, Masahiro Miura, Satoshi Ootsu, Hajime Miyajima, Masaru Nasu, Tadayoshi Okimoto, Masaaki Kodama, and Toshio Fujioka

Effect of Sucralfate on Antibiotic Therapy for Helicobacter pylori Infection in Mice
Antimicrob. Agents Chemother. 2004 48: 4582-4588. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kelly A. Sprandel, Christopher A. Schriever, Susan L. Pendland, John P. Quinn, Mark H. Gotfried, Suzanne Hackett, Mary Beth Graham, Larry H. Danziger, and Keith A. Rodvold

Pharmacokinetics and Pharmacodynamics of Intravenous Levofloxacin at 750 Milligrams and Various Doses of Metronidazole in Healthy Adult Subjects
Antimicrob. Agents Chemother. 2004 48: 4597-4605. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Rainer Gattringer, Eleonora Urbauer, Friederike Traunmüller, Markus Zeitlinger, Pejman Dehghanyar, Petra Zeleny, Wolfgang Graninger, Markus Müller, and Christian Joukhadar

Pharmacokinetics of Telithromycin in Plasma and Soft Tissues after Single-Dose Administration to Healthy Volunteers
Antimicrob. Agents Chemother. 2004 48: 4650-4653. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Scott Van Wart, Luann Phillips, Elizabeth A. Ludwig, Rene Russo, Diptee A. Gajjar, Akintunde Bello, Paul G. Ambrose, Christopher Costanzo, Thaddeus H. Grasela, Roger Echols, and Dennis M. Grasela

Population Pharmacokinetics and Pharmacodynamics of Garenoxacin in Patients with Community-Acquired Respiratory Tract Infections
Antimicrob. Agents Chemother. 2004 48: 4766-4777. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Antiviral Agents:

Stefania Paolucci, Fausto Baldanti, Giovanni Maga, Reynel Cancio, Maurizio Zazzi, Maurizio Zavattoni, Antonella Chiesa, Silvio Spadari, and Giuseppe Gerna

Gln145Met/Leu Changes in Human Immunodeficiency Virus Type 1 Reverse Transcriptase Confer Resistance to Nucleoside and Nonnucleoside Analogs and Impair Virus Replication
Antimicrob. Agents Chemother. 2004 48: 4611-4617. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mitsuaki Hosoya, Shuichi Mori, Akemi Tomoda, Kenji Mori, Yukio Sawaishi, Hiroshi Kimura, Shiro Shigeta, and Hitoshi Suzuki

Pharmacokinetics and Effects of Ribavirin following Intraventricular Administration for Treatment of Subacute Sclerosing Panencephalitis
Antimicrob. Agents Chemother. 2004 48: 4631-4635. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Brenda I. Hernandez-Santiago, Thierry Beltran, Lieven Stuyver, Chung K. Chu, and Raymond F. Schinazi

Metabolism of the Anti-Hepatitis C Virus Nucleoside ß-D-N⁴-Hydroxycytidine in Different Liver Cells
Antimicrob. Agents Chemother. 2004 48: 4636-4642. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Koen Andries, Hilde Azijn, Theo Thielemans, Donald Ludovici, Michael Kukla, Jan Heeres, Paul Janssen, Bart De Corte, Johan Vingerhoets, Rudi Pauwels, and Marie-Pierre de Béthune

TMC125, a Novel Next-Generation Nonnucleoside Reverse Transcriptase Inhibitor Active against Nonnucleoside Reverse Transcriptase Inhibitor-Resistant Human Immunodeficiency Virus Type 1
Antimicrob. Agents Chemother. 2004 48: 4680-4686. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Anne-Geneviève Marcelin, Cécile Dalban, Gilles Peytavin, Claire Lamotte, Rachid Agher, Constance Delaugerre, Marc Wirden, Françoise Conan, Sylvie Dantin, Christine Katlama, Dominique Costagliola, and Vincent Calvez

Clinically Relevant Interpretation of Genotype and Relationship to Plasma Drug Concentrations for Resistance to Saquinavir-Ritonavir in Human Immunodeficiency Virus Type 1 Protease Inhibitor-Experienced Patients
Antimicrob. Agents Chemother. 2004 48: 4687-4692. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Earl R. Kern, Deborah J. Bidanset, Caroll B. Hartline, Zhaohua Yan, Jiri Zemlicka, and Debra C. Quenelle

Oral Activity of a Methylenecyclopropane Analog, Cyclopropavir, in Animal Models for Cytomegalovirus Infections
Antimicrob. Agents Chemother. 2004 48: 4745-4753. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kai Lin, Ann D. Kwong, and Chao Lin

Combination of a Hepatitis C Virus NS3-NS4A Protease Inhibitor and Alpha Interferon Synergistically Inhibits Viral RNA Replication and Facilitates Viral RNA Clearance in Replicon Cells
Antimicrob. Agents Chemother. 2004 48: 4784-4792. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Anita Y. M. Howe, Johnathan Bloom, Carl J. Baldick, Christopher A. Benetatos, Huiming Cheng, Joel S. Christensen, Srinivas K. Chunduru, Glen A. Coburn, Boris Feld, Ariamala Gopalsamy, William P. Gorczyca, Steve Herrmann, Stephen Johann, Xiaoqun Jiang, Michelle L. Kimberland, Girija Krisnamurthy, Matthew Olson, Mark Orlowski, Steve Swanberg, Ian Thompson, Megan Thorn, Alfred Del Vecchio, Dorothy C. Young, Marja van Zeijl, John W. Ellingboe, Janis Upeslacis, Marc Collett, Tarek S. Mansour, and John F. O'Connell

Novel Nonnucleoside Inhibitor of Hepatitis C Virus RNA-Dependent RNA Polymerase
Antimicrob. Agents Chemother. 2004 48: 4813-4821. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Elizabeth Johnston, Mark A. Winters, Soo-Yon Rhee, Thomas C. Merigan, Celia A. Schiffer, and Robert W. Shafer

Association of a Novel Human Immunodeficiency Virus Type 1 Protease Substrate Cleft Mutation, L23I, with Protease Inhibitor Therapy and In Vitro Drug Resistance
Antimicrob. Agents Chemother. 2004 48: 4864-4868. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Action:

R. Caubet, F. Pedarros-Caubet, M. Chu, E. Freye, M. de Belém Rodrigues, J. M. Moreau, and W. J. Ellison

A Radio Frequency Electric Current Enhances Antibiotic Efficacy against Bacterial Biofilms
Antimicrob. Agents Chemother. 2004 48: 4662-4664. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Julie Millet, Sandrine Alibert, Marylin Torrentino-Madamet, Christophe Rogier, Christiane Santelli-Rouvier, Patricia Bigot, Joel Mosnier, Eric Baret, Jacques Barbe, Daniel Parzy, and Bruno Pradines

Polymorphism in Plasmodium falciparum Drug Transporter Proteins and Reversal of In Vitro Chloroquine Resistance by a 9,10-Dihydroethanoanthracene Derivative
Antimicrob. Agents Chemother. 2004 48: 4869-4872. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jill Thompson, Catherine A. Pratt, and Albert E. Dahlberg

Effects of a Number of Classes of 50S Inhibitors on Stop Codon Readthrough during Protein Synthesis
Antimicrob. Agents Chemother. 2004 48: 4889-4891. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

George Carter, Lowell S. Young, and Luiz E. Bermudez

A Subinhibitory Concentration of Clarithromycin Inhibits Mycobacterium avium Biofilm Formation
Antimicrob. Agents Chemother. 2004 48: 4907-4910. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Chemistry; Biosynthesis:

Shannon L. Ward, Zhihao Hu, Andreas Schirmer, Ralph Reid, W. Peter Revill, Christopher D. Reeves, Oleg V. Petrakovsky, Steven D. Dong, and Leonard Katz

Chalcomycin Biosynthesis Gene Cluster from Streptomyces bikiniensis: Novel Features of an Unusual Ketolide Produced through Expression of the chm Polyketide Synthase in Streptomyces fradiae
Antimicrob. Agents Chemother. 2004 48: 4703-4712. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Letters:

Marie-Frédérique Lartigue, Laurent Poirel, and Patrice Nordmann

First Detection of a Carbapenem-Hydrolyzing Metalloenzyme in an Enterobacteriaceae Isolate in France
Antimicrob. Agents Chemother. 2004 48: 4929-4930. [Full Text] [PDF] [Reprints and Permissions]  

Errata:

Jackie K. Imai, Gaurav Singh, Karl V. Clemons, and David A. Stevens

Efficacy of Posaconazole in a Murine Model of Central Nervous System Aspergillosis
Antimicrob. Agents Chemother. 2004 48: 4931. [Full Text] [PDF] [Reprints and Permissions]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.