AAC -- Table of Contents (November 1 2005, 49 [11])

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Contents: November 2005, Volume 49, Issue 11

       Pharmacology

       Analytical Procedures

       Mechanisms of Resistance

       Clinical Therapeutics

       Antiviral Agents

       Susceptibility

       Mechanisms of Action

       Experimental Therapeutics

       Chemistry; Biosynthesis

       Letters

       Errata

Other Issues

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Table of Contents

[Index by Author]

To see an article, click its [Full Text], [Abstract] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

Pharmacology:

Population Pharmacokinetics of Rifapentine and Its Primary Desacetyl Metabolite in South African Tuberculosis Patients
Grant Langdon, Justin Wilkins, Lynn McFadyen, Helen McIlleron, Peter Smith, and Ulrika S. H. Simonsson
Antimicrob. Agents Chemother. November 2005 49: 4429-4436;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pharmacokinetics, Safety, and Tolerability of Caspofungin in Children and Adolescents
Thomas J. Walsh, Peter C. Adamson, Nita L. Seibel, Patricia M. Flynn, Michael N. Neely, Cindy Schwartz, Aziza Shad, Sheldon L. Kaplan, Maureen M. Roden, Julie A. Stone, Alisha Miller, Susan K. Bradshaw, Susan X. Li, Carole A. Sable, and Nicholas A. Kartsonis
Antimicrob. Agents Chemother. November 2005 49: 4536-4545;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Analytical Procedures:

Application of Quantitative Real-Time Reverse Transcription-PCR in Assessing Drug Efficacy against the Intracellular Pathogen Cryptosporidium parvum In Vitro
Xiaomin Cai, Keith M. Woods, Steve J. Upton, and Guan Zhu
Antimicrob. Agents Chemother. November 2005 49: 4437-4442;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mechanisms of Resistance:

TEM-109 (CMT-5), a Natural Complex Mutant of TEM-1 ß-Lactamase Combining the Amino Acid Substitutions of TEM-6 and TEM-33 (IRT-5)
F. Robin, J. Delmas, C. Chanal, D. Sirot, J. Sirot, and R. Bonnet
Antimicrob. Agents Chemother. November 2005 49: 4443-4447;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Fitness Cost Due to Mutations in the 16S rRNA Associated with Spectinomycin Resistance in Chlamydia psittaci 6BC
Rachel Binet and Anthony T. Maurelli
Antimicrob. Agents Chemother. November 2005 49: 4455-4464;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Novel Acquired Metallo-ß-Lactamase Gene, bla_SIM-1, in a Class 1 Integron from Acinetobacter baumannii Clinical Isolates from Korea
Kyungwon Lee, Jong Hwa Yum, Dongeun Yong, Hyuk Min Lee, Heung Dong Kim, Jean-Denis Docquier, Gian Maria Rossolini, and Yunsop Chong
Antimicrob. Agents Chemother. November 2005 49: 4485-4491;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Use of Ribotyping To Retrospectively Identify Methicillin-Resistant Staphylococcus aureus Isolates from Phase 3 Clinical Trials for Tigecycline That Are Genotypically Related to Community-Associated Isolates
Fionnuala McAleese, Ellen Murphy, Timothy Babinchak, Guy Singh, Battouli Said-Salim, Barry Kreiswirth, Paul Dunman, John O'Connell, Steven J. Projan, and Patricia A. Bradford
Antimicrob. Agents Chemother. November 2005 49: 4521-4529;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pseudomonas aeruginosa AmpR Is a Global Transcriptional Factor That Regulates Expression of AmpC and PoxB ß-Lactamases, Proteases, Quorum Sensing, and Other Virulence Factors
Kok-Fai Kong, Suriya Ravi Jayawardena, Shalaka Dayaram Indulkar, Aimee del Puerto, Chong-Lek Koh, Niels Høiby, and Kalai Mathee
Antimicrob. Agents Chemother. November 2005 49: 4567-4575;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mechanisms of Azole Resistance in a Clinical Isolate of Candida tropicalis
Patrick Vandeputte, Gérald Larcher, Thierry Bergès, Gilles Renier, Dominique Chabasse, and Jean-Philippe Bouchara
Antimicrob. Agents Chemother. November 2005 49: 4608-4615;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Gene Expression Analysis of the Mechanism of Natural Sb(V) Resistance in Leishmania donovani Isolates from Nepal
Saskia Decuypere, Suman Rijal, Vanessa Yardley, Simonne De Doncker, Thierry Laurent, Basudha Khanal, François Chappuis, and Jean-Claude Dujardin
Antimicrob. Agents Chemother. November 2005 49: 4616-4621;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Amino Acid Mutations Essential to Production of an Altered PBP 2X Conferring High-Level ß-Lactam Resistance in a Clinical Isolate of Streptococcus pneumoniae
Anthony M. Smith and Keith P. Klugman
Antimicrob. Agents Chemother. November 2005 49: 4622-4627;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Expression of the mef(E) Gene Encoding the Macrolide Efflux Pump Protein Increases in Streptococcus pneumoniae with Increasing Resistance to Macrolides
Aleksandra K. Wierzbowski, Dave Boyd, Michael Mulvey, Daryl J. Hoban, and George G. Zhanel
Antimicrob. Agents Chemother. November 2005 49: 4635-4640;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Virulence Factors of Escherichia coli Isolates That Produce CTX-M-Type Extended-Spectrum ß-Lactamases
Johann D. D. Pitout, Kevin B. Laupland, Deirdre L. Church, Megan L. Menard, and James R. Johnson
Antimicrob. Agents Chemother. November 2005 49: 4667-4670;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

DNA Sequence and Comparative Genomics of pAPEC-O2-R, an Avian Pathogenic Escherichia coli Transmissible R Plasmid
Timothy J. Johnson, Kylie E. Siek, Sara J. Johnson, and Lisa K. Nolan
Antimicrob. Agents Chemother. November 2005 49: 4681-4688;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Molecular Analysis of the Simultaneous Production of Two SHV-Type Extended-Spectrum Beta-Lactamases in a Clinical Isolate of Enterobacter cloacae by Using Single-Nucleotide Polymorphism Genotyping
Dóra Szabó, Melissa A. Melan, Andrea M. Hujer, Robert A. Bonomo, Kristine M. Hujer, Christopher R. Bethel, Katalin Kristóf, and David L. Paterson
Antimicrob. Agents Chemother. November 2005 49: 4716-4720;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Molecular Mechanisms of ß-Lactam Resistance Mediated by AmpC Hyperproduction in Pseudomonas aeruginosa Clinical Strains
Carlos Juan, María D. Maciá, Olivia Gutiérrez, Carmen Vidal, José L. Pérez, and Antonio Oliver
Antimicrob. Agents Chemother. November 2005 49: 4733-4738;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Spontaneous Conversion to Quinolone and Fluoroquinolone Resistance among Wild-Type Escherichia coli Isolates in Relation to Phylogenetic Background and Virulence Genotype
James R. Johnson, Brian Johnston, Michael A. Kuskowski, Raul Colodner, and Raul Raz
Antimicrob. Agents Chemother. November 2005 49: 4739-4744;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

CTX-M-2 and a New CTX-M-39 Enzyme Are the Major Extended-Spectrum Beta-Lactamases in Multiple Escherichia coli Clones Isolated in Tel Aviv, Israel
Inna Chmelnitsky, Yehuda Carmeli, Azita Leavitt, Mitchell J. Schwaber, and Shiri Navon-Venezia
Antimicrob. Agents Chemother. November 2005 49: 4745-4750;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Increased Mutation Frequencies in Escherichia coli Isolates Harboring Extended-Spectrum ß-Lactamases
María-Rosario Baquero, Juan Carlos Galán, María del Carmen Turrientes, Rafael Cantón, Teresa M. Coque, José Luis Martínez, and Fernando Baquero
Antimicrob. Agents Chemother. November 2005 49: 4754-4756;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Kinetics Study of KPC-3, a Plasmid-Encoded Class A Carbapenem-Hydrolyzing ß-Lactamase
Jimena Alba, Yoshikazu Ishii, Kenneth Thomson, Ellen Smith Moland, and Keizo Yamaguchi
Antimicrob. Agents Chemother. November 2005 49: 4760-4762;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

AmpC and OprD Are Not Involved in the Mechanism of Imipenem Hypersusceptibility among Pseudomonas aeruginosa Isolates Overexpressing the mexCD-oprJ Efflux Pump
Daniel J. Wolter, Nancy D. Hanson, and Philip D. Lister
Antimicrob. Agents Chemother. November 2005 49: 4763-4766;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

TLA-2, a Novel Ambler Class A Expanded-Spectrum ß-Lactamase
Delphine Girlich, Laurent Poirel, Andreas Schlüter, and Patrice Nordmann
Antimicrob. Agents Chemother. November 2005 49: 4767-4770;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Recombination between the dfrA12-orfF-aadA2 Cassette Array and an aadA1 Gene Cassette Creates a Hybrid Cassette, aadA8b
Alicia M. Gestal, H. W. Stokes, Sally R. Partridge, and Ruth M. Hall
Antimicrob. Agents Chemother. November 2005 49: 4771-4774;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

mmpL7 Gene of Mycobacterium tuberculosis Is Responsible for Isoniazid Efflux in Mycobacterium smegmatis
Maria R. Pasca, Paola Guglierame, Edda De Rossi, Francesca Zara, and Giovanna Riccardi
Antimicrob. Agents Chemother. November 2005 49: 4775-4777;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Use of an Efflux-Deficient Streptococcus pneumoniae Strain Panel To Identify ABC-Class Multidrug Transporters Involved in Intrinsic Resistance to Antimicrobial Agents
Gregory T. Robertson, Timothy B. Doyle, and A. Simon Lynch
Antimicrob. Agents Chemother. November 2005 49: 4781-4783;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

High Prevalence of Glycopeptide Resistance Genes vanB, vanD, and vanG Not Associated with Enterococci in Human Fecal Flora
M.-C. Domingo, A. Huletsky, R. Giroux, K. Boissinot, F. J. Picard, P. Lebel, M. J. Ferraro, and M. G. Bergeron
Antimicrob. Agents Chemother. November 2005 49: 4784-4786;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Multiplex PCR for Simultaneous Detection of Macrolide and Tetracycline Resistance Determinants in Streptococci
Surbhi Malhotra-Kumar, Christine Lammens, Jasper Piessens, and Herman Goossens
Antimicrob. Agents Chemother. November 2005 49: 4798-4800;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Clinical Therapeutics:

Antibiotic Abscess Penetration: Fosfomycin Levels Measured in Pus and Simulated Concentration-Time Profiles
Robert Sauermann, Rudolf Karch, Herbert Langenberger, Joachim Kettenbach, Bernhard Mayer-Helm, Martina Petsch, Claudia Wagner, Thomas Sautner, Rainer Gattringer, Georgios Karanikas, and Christian Joukhadar
Antimicrob. Agents Chemother. November 2005 49: 4448-4454;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Prior Antimicrobial Therapy and Risk for Hospital-Acquired Candida glabrata and Candida krusei Fungemia: a Case-Case-Control Study
Michael Y. Lin, Yehuda Carmeli, Jennifer Zumsteg, Ernesto L. Flores, Jocelyn Tolentino, Pranavi Sreeramoju, and Stephen G. Weber
Antimicrob. Agents Chemother. November 2005 49: 4555-4560;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Safety and Efficacy of Tigecycline in Treatment of Skin and Skin Structure Infections: Results of a Double-Blind Phase 3 Comparison Study with Vancomycin-Aztreonam
Johannes Breedt, Jüri Teras, Janis Gardovskis, Frans Jacobus Maritz, Tiit Vaasna, Douglas Patrick Ross, Martine Gioud-Paquet, Nathalie Dartois, Evelyn J. Ellis-Grosse, Evan Loh for the Tigecycline 305 cSSSI Study Group
Antimicrob. Agents Chemother. November 2005 49: 4658-4666;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Efficacy of Penicillin versus Cefdinir in Eradication of Group A Streptococci and Tonsillar Flora
Itzhak Brook and Perry A. Foote
Antimicrob. Agents Chemother. November 2005 49: 4787-4788;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Recovery of Interfering Bacteria in the Nasopharynx following Antimicrobial Therapy of Acute Maxillary Sinusitis with Telithromycin or Amoxicillin-Clavulanate
Itzhak Brook and Jeffrey N. Hausfeld
Antimicrob. Agents Chemother. November 2005 49: 4793-4794;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Effectiveness of Anidulafungin in Eradicating Candida Species in Invasive Candidiasis
M. A. Pfaller, D. J. Diekema, L. Boyken, S. A. Messer, S. Tendolkar, R. J. Hollis, and B. P. Goldstein
Antimicrob. Agents Chemother. November 2005 49: 4795-4797;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antiviral Agents:

Anti-Human Immunodeficiency Virus Type 1 Activity of the Nonnucleoside Reverse Transcriptase Inhibitor GW678248 in Combination with Other Antiretrovirals against Clinical Isolate Viruses and In Vitro Selection for Resistance
Richard J. Hazen, Robert J. Harvey, Marty H. St. Clair, Robert G. Ferris, George A. Freeman, Jeffrey H. Tidwell, Lee T. Schaller, Jill R. Cowan, Steven A. Short, Karen R. Romines, Joseph H. Chan, and Lawrence R. Boone
Antimicrob. Agents Chemother. November 2005 49: 4465-4473;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Relationship of Pleconaril Susceptibility and Clinical Outcomes in Treatment of Common Colds Caused by Rhinoviruses
Daniel C. Pevear, Frederick G. Hayden, Tina M. Demenczuk, Linda R. Barone, Mark A. McKinlay, and Marc S. Collett
Antimicrob. Agents Chemother. November 2005 49: 4492-4499;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Randomized, Placebo-Controlled Trial of Nonpegylated and Pegylated Forms of Recombinant Human Alpha Interferon 2a for Suppression of Dengue Virus Viremia in Rhesus Monkeys
C. Ajariyakhajorn, M. P. Mammen, Jr., T. P. Endy, M. Gettayacamin, A. Nisalak, S. Nimmannitya, and D. H. Libraty
Antimicrob. Agents Chemother. November 2005 49: 4508-4514;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Susceptibilities of Antiviral-Resistant Influenza Viruses to Novel Neuraminidase Inhibitors
Vasiliy P. Mishin, Frederick G. Hayden, and Larisa V. Gubareva
Antimicrob. Agents Chemother. November 2005 49: 4515-4520;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

High Potency of Indolyl Aryl Sulfone Nonnucleoside Inhibitors towards Drug-Resistant Human Immunodeficiency Virus Type 1 Reverse Transcriptase Mutants Is Due to Selective Targeting of Different Mechanistic Forms of the Enzyme
Reynel Cancio, Romano Silvestri, Rino Ragno, Marino Artico, Gabriella De Martino, Giuseppe La Regina, Emmanuele Crespan, Samantha Zanoli, Ulrich Hübscher, Silvio Spadari, and Giovanni Maga
Antimicrob. Agents Chemother. November 2005 49: 4546-4554;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

TAK-652 Inhibits CCR5-Mediated Human Immunodeficiency Virus Type 1 Infection In Vitro and Has Favorable Pharmacokinetics in Humans
Masanori Baba, Katsunori Takashima, Hiroshi Miyake, Naoyuki Kanzaki, Koichiro Teshima, Xin Wang, Mitsuru Shiraishi, and Yuji Iizawa
Antimicrob. Agents Chemother. November 2005 49: 4584-4591;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Organotypic Epithelial Raft Cultures as a Model for Evaluating Compounds against Alphaherpesviruses
Graciela Andrei, Joost van den Oord, Pierre Fiten, Ghislain Opdenakker, Chris De Wolf-Peeters, Erik De Clercq, and Robert Snoeck
Antimicrob. Agents Chemother. November 2005 49: 4671-4680;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mouse Adenovirus Type 1 Infection in SCID Mice: an Experimental Model for Antiviral Therapy of Systemic Adenovirus Infections
L. Lenaerts, E. Verbeken, E. De Clercq, and L. Naesens
Antimicrob. Agents Chemother. November 2005 49: 4689-4699;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Analysis of Binding Sites for the New Small-Molecule CCR5 Antagonist TAK-220 on Human CCR5
Masao Nishikawa, Katsunori Takashima, Toshiya Nishi, Rika A. Furuta, Naoyuki Kanzaki, Yoshio Yamamoto, and Jun-ichi Fujisawa
Antimicrob. Agents Chemother. November 2005 49: 4708-4715;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Maraviroc (UK-427,857), a Potent, Orally Bioavailable, and Selective Small-Molecule Inhibitor of Chemokine Receptor CCR5 with Broad-Spectrum Anti-Human Immunodeficiency Virus Type 1 Activity
Patrick Dorr, Mike Westby, Susan Dobbs, Paul Griffin, Becky Irvine, Malcolm Macartney, Julie Mori, Graham Rickett, Caroline Smith-Burchnell, Carolyn Napier, Rob Webster, Duncan Armour, David Price, Blanda Stammen, Anthony Wood, and Manos Perros
Antimicrob. Agents Chemother. November 2005 49: 4721-4732;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Susceptibility:

Photodynamic Sensitization of Leishmania amazonensis in both Extracellular and Intracellular Stages with Aluminum Phthalocyanine Chloride for Photolysis In Vitro
Sujoy Dutta, Debalina Ray, Bala K. Kolli, and Kwang-Poo Chang
Antimicrob. Agents Chemother. November 2005 49: 4474-4484;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Assessment of Methylene Blue on Chloroquine-Sensitive and -Resistant Plasmodium falciparum Strains Reveals Synergistic Action with Artemisinins
Monique Akoachere, Kathrin Buchholz, Elisabeth Fischer, Jürgen Burhenne, Walter E. Haefeli, R. Heiner Schirmer, and Katja Becker
Antimicrob. Agents Chemother. November 2005 49: 4592-4597;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Differential Antibiotic Susceptibilities of Starved Mycobacterium tuberculosis Isolates
Zhifang Xie, Noman Siddiqi, and Eric J. Rubin
Antimicrob. Agents Chemother. November 2005 49: 4778-4780;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

New Mycobacterium avium Antifolate Shows Synergistic Effect when Used in Combination with Dihydropteroate Synthase Inhibitors
W. J. Suling, L. E. Seitz, R. C. Reynolds, and W. W. Barrow
Antimicrob. Agents Chemother. November 2005 49: 4801-4803;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Impact of Mass Distribution of Azithromycin on the Antibiotic Susceptibilities of Ocular Chlamydia trachomatis
Anthony W. Solomon, Zeena Mohammed, Patrick A. Massae, John F. Shao, Allen Foster, David C. W. Mabey, and Rosanna W. Peeling
Antimicrob. Agents Chemother. November 2005 49: 4804-4806;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mechanisms of Action:

Identification of a Dithiazoline Inhibitor of Escherichia coli L,D-Carboxypeptidase A
Ellen Z. Baum, Steven M. Crespo-Carbone, Barbara Foleno, Sean Peng, Jamese J. Hilliard, Darren Abbanat, Raul Goldschmidt, and Karen Bush
Antimicrob. Agents Chemother. November 2005 49: 4500-4507;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antibacterial Activity of Human Neutrophil Defensin HNP-1 Analogs without Cysteines
Jobin Varkey and Ramakrishnan Nagaraj
Antimicrob. Agents Chemother. November 2005 49: 4561-4566;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

A Class of Pantothenic Acid Analogs Inhibits Plasmodium falciparum Pantothenate Kinase and Represses the Proliferation of Malaria Parasites
Christina Spry, Christina L. L. Chai, Kiaran Kirk, and Kevin J. Saliba
Antimicrob. Agents Chemother. November 2005 49: 4649-4657;
[Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]

Experimental Therapeutics:

Evaluation of Antibiotic Treatment against "Candidatus Helicobacter suis" in a Mouse Model
A. Hellemans, A. Decostere, F. Haesebrouck, and R. Ducatelle
Antimicrob. Agents Chemother. November 2005 49: 4530-4535;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Inhibitory Activities of Epidermal Growth Factor Receptor Tyrosine Kinase-Targeted Dihydroxyisoflavone and Trihydroxydeoxybenzoin Derivatives on Sarcocystis neurona, Neospora caninum, and Cryptosporidium parvum Development
G. Gargala, A. Baishanbo, L. Favennec, A. François, J. J. Ballet, and J.-F. Rossignol
Antimicrob. Agents Chemother. November 2005 49: 4628-4634;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Comparative Effects of Two Neutralizing Anti-Respiratory Syncytial Virus (RSV) Monoclonal Antibodies in the RSV Murine Model: Time versus Potency
Asunción Mejías, Susana Chávez-Bueno, Ana María Ríos, Mónica Fonseca Aten, Brett Raynor, Estrella Peromingo, Perla Soni, Kurt D. Olsen, Peter A. Kiener, Ana María Gómez, Hasan S. Jafri, and Octavio Ramilo
Antimicrob. Agents Chemother. November 2005 49: 4700-4707;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Combination Therapy with Terbinafine and Amphotericin B in a Rabbit Model of Experimental Invasive Aspergillosis
William R. Kirkpatrick, Ana C. Vallor, Robert K. McAtee, Neil S. Ryder, Annette W. Fothergill, Michael G. Rinaldi, and Thomas F. Patterson
Antimicrob. Agents Chemother. November 2005 49: 4751-4753;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Activities of Flucytosine, Fluconazole, Amphotericin B, and Micafungin in a Murine Model of Disseminated Infection by Candida glabrata
Marçal Mariné, Carolina Serena, Belkys Fernández-Torres, F. Javier Pastor, and Josep Guarro
Antimicrob. Agents Chemother. November 2005 49: 4757-4759;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Therapeutic Effects of Bacteriophage Cpl-1 Lysin against Streptococcus pneumoniae Endocarditis in Rats
J. M. Entenza, J. M. Loeffler, D. Grandgirard, V. A. Fischetti, and P. Moreillon
Antimicrob. Agents Chemother. November 2005 49: 4789-4792;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Chemistry; Biosynthesis:

Nystatin Biosynthesis and Transport: nysH and nysG Genes Encoding a Putative ABC Transporter System in Streptomyces noursei ATCC 11455 Are Required for Efficient Conversion of 10-Deoxynystatin to Nystatin
Håvard Sletta, Sven E. F. Borgos, Per Bruheim, Olga N. Sekurova, Hans Grasdalen, Randi Aune, Trond E. Ellingsen, and Sergey B. Zotchev
Antimicrob. Agents Chemother. November 2005 49: 4576-4583;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Phosphinothricin Tripeptide Synthetases in Streptomyces viridochromogenes Tü494
Dirk Schwartz, Nicolas Grammel, Eva Heinzelmann, Ullrich Keller, and Wolfgang Wohlleben
Antimicrob. Agents Chemother. November 2005 49: 4598-4607;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Horizontal Transfer of Iturin A Operon, itu, to Bacillus subtilis 168 and Conversion into an Iturin A Producer
Kenji Tsuge, Satoka Inoue, Takashi Ano, Mitsuhiro Itaya, and Makoto Shoda
Antimicrob. Agents Chemother. November 2005 49: 4641-4648;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Letters:

Mutations Conferring Drug Resistance in Malaria Parasite Drug Transporters Pgh1 and PfCRT Do Not Affect Steady-State Vacuolar Ca²⁺
Giancarlo A. Biagini, David A. Fidock, Patrick G. Bray, and Stephen A. Ward
Antimicrob. Agents Chemother. November 2005 49: 4807-4808;
[Full Text] [PDF] [Reprints and Permissions]

First Outbreak of Klebsiella pneumoniae Clinical Isolates Producing GES-5 and SHV-12 Extended-Spectrum ß-Lactamases in Korea
Seok Hoon Jeong, Il Kwon Bae, Doelman Kim, Seong Geun Hong, Jae Seok Song, Jung Hun Lee, and Sang Hee Lee
Antimicrob. Agents Chemother. November 2005 49: 4809-4810;
[Full Text] [PDF] [Reprints and Permissions]

Clinical Isolates of the Spain¹⁴-5 Clone of Streptococcus pneumoniae Carry a Recombinant rpoB Gene
M. J. Ferrándiz, E. Pérez-Trallero, J. M. Marimón, and A. G. de la Campa
Antimicrob. Agents Chemother. November 2005 49: 4811-4813;
[Full Text] [PDF] [Reprints and Permissions]

Pharmacokinetics of Colistin Methanesulfonate and Colistin in a Critically Ill Patient Receiving Continuous Venovenous Hemodiafiltration
J. Li, C. R. Rayner, R. L. Nation, R. Deans, R. Boots, N. Widdecombe, A. Douglas, and J. Lipman
Antimicrob. Agents Chemother. November 2005 49: 4814-4815;
[Full Text] [PDF] [Reprints and Permissions]

Improved Outcomes with Linezolid for Methicillin-Resistant Staphylococcus aureus Infections: Better Drug or Reduced Vancomycin Susceptibility?
Benjamin P. Howden, Patrick G. P. Charles, Paul D. R. Johnson, Peter B. Ward, M. Lindsay Grayson, John A. Weigelt, Kamal Itani, Dennis Stevens, William Lau, Matthew Dryden, and Charles Knirsch
Antimicrob. Agents Chemother. November 2005 49: 4816-4817;
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Errata:

Role of embB Codon 306 Mutations in Mycobacterium tuberculosis Revisited: a Novel Association with Broad Drug Resistance and IS6110 Clustering Rather than Ethambutol Resistance
Manzour Hernando Hazbón et al.
Antimicrob. Agents Chemother. November 2005 49: 4818
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Evidence for Reduction in Breakpoints Used To Determine Vancomycin Susceptibility in Staphylococcus aureus
Mandy Wootton, T. R. Walsh, and A. P. MacGowan
Antimicrob. Agents Chemother. November 2005 49: 4819
[Full Text] [PDF] [Reprints and Permissions]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.