Contents: March 2005, Volume 49, Issue 3        Minireviews        Experimental Therapeutics        Susceptibility        Mechanisms of Resistance        Mechanisms of Action        Antiviral Agents        Clinical Therapeutics        Pharmacology        Letters        Errata Other Issues

Table of Contents

[Index by Author]

To see an article, click its [Full Text], [Abstract] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

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Minireviews:

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Human Cytomegalovirus Resistance to Antiviral Drugs C. Gilbert and G. Boivin Antimicrob. Agents Chemother. March 2005 49: 873-883; [Full Text] [PDF] [Reprints and Permissions]

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Experimental Therapeutics:

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Evaluation of Ceftobiprole in a Rabbit Model of Aortic Valve Endocarditis Due to Methicillin-Resistant and Vancomycin-Intermediate Staphylococcus aureus Henry F. Chambers Antimicrob. Agents Chemother. March 2005 49: 884-888; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Bactericidal Effects of Toluidine Blue-Mediated Photodynamic Action on Vibrio vulnificus Tak-Wah Wong, Yin-Yi Wang, Hamm-Ming Sheu, and Yin-Ching Chuang Antimicrob. Agents Chemother. March 2005 49: 895-902; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Comparative Bacteriological Efficacy of Pharmacokinetically Enhanced Amoxicillin-Clavulanate against Streptococcus pneumoniae with Elevated Amoxicillin MICs and Haemophilus influenzae Valerie Berry, Jennifer Hoover, Christine Singley, and Gary Woodnutt Antimicrob. Agents Chemother. March 2005 49: 908-915; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Pharmacodynamics of Amphotericin B, Itraconazole, and Voriconazole against Aspergillus, Fusarium, and Scedosporium spp. Russell E. Lewis, Nathan P. Wiederhold, and Michael E. Klepser Antimicrob. Agents Chemother. March 2005 49: 945-951; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pulmonary Damage and Bacterial Load in Assessment of the Efficacy of Simulated Human Treatment-Like Amoxicillin (2,000 Milligrams) Therapy of Experimental Pneumococcal Pneumonia Caused by Strains for Which Amoxicillin MICs Differ Matilde Gracia, Carmina Martínez-Marín, Lorena Huelves, Maria J. Giménez, Lorenzo Aguilar, Antonio Carcas, Carmen Ponte, and Francisco Soriano Antimicrob. Agents Chemother. March 2005 49: 996-1001; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Activity of Gemifloxacin against Quinolone-Resistant Streptococcus pneumoniae Strains In Vitro and in a Mouse Pneumonia Model E. Azoulay-Dupuis, J. P. Bédos, J. Mohler, P. Moine, C. Cherbuliez, G. Peytavin, B. Fantin, and T. Köhler Antimicrob. Agents Chemother. March 2005 49: 1046-1054; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antiamoebic and Toxicity Studies of a Carbamic Acid Derivative and Its Therapeutic Effect in a Hamster Model of Hepatic Amoebiasis Cynthia Ordaz-Pichardo, Mineko Shibayama, Saúl Villa-Treviño, Myriam Arriaga-Alba, Enrique Angeles, and Mireya de la Garza Antimicrob. Agents Chemother. March 2005 49: 1160-1168; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Experimental Bacteriophage Protection against Staphylococcus aureus Abscesses in a Rabbit Model Quintin F. Wills, Claire Kerrigan, and James S. Soothill Antimicrob. Agents Chemother. March 2005 49: 1220-1221; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Susceptibility:

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In Vitro Activity of Tebipenem, a New Oral Carbapenem Antibiotic, against Penicillin-Nonsusceptible Streptococcus pneumoniae Reiko Kobayashi, Mami Konomi, Keiko Hasegawa, Miyuki Morozumi, Keisuke Sunakawa, and Kimiko Ubukata Antimicrob. Agents Chemother. March 2005 49: 889-894; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Synthesis and Antileishmanial Activities of Novel 3-Substituted Quinolines André Gustavo Tempone, Ana Cláudia Melo Pompeu da Silva, Carlos Alberto Brandt, Fernanda Scalzaretto Martinez, Samanta Etel Treiger Borborema, Maria Amélia Barata da Silveira, and Heitor Franco de Andrade, Jr. Antimicrob. Agents Chemother. March 2005 49: 1076-1080; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Rifampin-Resistant RNA Polymerase Mutants of Chlamydia trachomatis Remain Susceptible to the Ansamycin Rifalazil Robert J. Suchland, Agnès Bourillon, Erick Denamur, Walter E. Stamm, and David M. Rothstein Antimicrob. Agents Chemother. March 2005 49: 1120-1126; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activity of Ramoplanin against Clostridium difficile, Including Strains with Reduced Susceptibility to Vancomycin or with Resistance to Metronidazole T. Peláez, L. Alcalá, R. Alonso, A. Martín-López, V. García-Arias, M. Marín, and E. Bouza Antimicrob. Agents Chemother. March 2005 49: 1157-1159; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

A Novel Engineered Peptide, a Narrow-Spectrum Antibiotic, is Effective against Vancomycin-Resistant Enterococcus faecalis Xiao-Qing Qiu, Jie Zhang, He Wang, and George Y. Wu Antimicrob. Agents Chemother. March 2005 49: 1184-1189; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Activity of Cathelicidin Peptides against Chlamydia spp. Manuela Donati, Korinne Di Leo, Monica Benincasa, Francesca Cavrini, Silvia Accardo, Alessandra Moroni, Renato Gennaro, and Roberto Cevenini Antimicrob. Agents Chemother. March 2005 49: 1201-1202; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Synergistic Killing of Streptococcus pneumoniae with the Bacteriophage Lytic Enzyme Cpl-1 and Penicillin or Gentamicin Depends on the Level of Penicillin Resistance Svetolik Djurkovic, Jutta M. Loeffler, and Vincent A. Fischetti Antimicrob. Agents Chemother. March 2005 49: 1225-1228; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Combined Activity In Vitro of Caspofungin, Amphotericin B, and Azole Agents against Itraconazole-Resistant Clinical Isolates of Aspergillus fumigatus Manuel Cuenca-Estrella, Alicia Gomez-Lopez, Guillermo Garcia-Effron, Laura Alcazar-Fuoli, Emilia Mellado, Maria J. Buitrago, and Juan L. Rodriguez-Tudela Antimicrob. Agents Chemother. March 2005 49: 1232-1235; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Susceptibility of Streptococcus mutans and Actinobacillus actinomycetemcomitans to Bactericidal Activity of Human ß-Defensin 3 in Biological Fluids Giuseppantonio Maisetta, Giovanna Batoni, Semih Esin, Giorgio Raco, Daria Bottai, Flavia Favilli, Walter Florio, and Mario Campa Antimicrob. Agents Chemother. March 2005 49: 1245-1248; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activity of the Histatin Derivative P-113 against Multidrug-Resistant Pathogens Responsible for Pneumonia in Immunocompromised Patients Andrea Giacometti, Oscar Cirioni, Wojciech Kamysz, Giuseppina D'Amato, Carmela Silvestri, Maria Simona Del Prete, Alberto Licci, Alessandra Riva, Jerzy Lukasiak, and Giorgio Scalise Antimicrob. Agents Chemother. March 2005 49: 1249-1252; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Mechanisms of Resistance:

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Emergence of Resistance to Rifampin and Rifalazil in Chlamydophila pneumoniae and Chlamydia trachomatis Andrei Kutlin, Stephan Kohlhoff, Patricia Roblin, Margaret R. Hammerschlag, and Paul Riska Antimicrob. Agents Chemother. March 2005 49: 903-907; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Molecular Analysis of Resistance to Streptogramin A Compounds Conferred by the Vga Proteins of Staphylococci Olivier Chesneau, Heidi Ligeret, Negin Hosan-Aghaie, Anne Morvan, and Elie Dassa Antimicrob. Agents Chemother. March 2005 49: 973-980; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Influence of Transcriptional Activator RamA on Expression of Multidrug Efflux Pump AcrAB and Tigecycline Susceptibility in Klebsiella pneumoniae Alexey Ruzin, Melissa A. Visalli, David Keeney, and Patricia A. Bradford Antimicrob. Agents Chemother. March 2005 49: 1017-1022; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Transcriptional Analysis of the vanC Cluster from Enterococcus gallinarum Strains with Constitutive and Inducible Vancomycin Resistance Diana Panesso, Lorena Abadía-Patiño, Natasha Vanegas, Peter E. Reynolds, Patrice Courvalin, and Cesar A. Arias Antimicrob. Agents Chemother. March 2005 49: 1060-1066; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

CmeR Functions as a Transcriptional Repressor for the Multidrug Efflux Pump CmeABC in Campylobacter jejuni Jun Lin, Masato Akiba, Orhan Sahin, and Qijing Zhang Antimicrob. Agents Chemother. March 2005 49: 1067-1075; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

High Prevalence of Markers for Sulfadoxine and Pyrimethamine Resistance in Plasmodium falciparum in the Absence of Drug Pressure in the Ashanti Region of Ghana Florian Marks, Jennifer Evans, Christian G. Meyer, Edmund N. Browne, Christa Flessner, Vera von Kalckreuth, Teunis A. Eggelte, Rolf D. Horstmann, and Jürgen May Antimicrob. Agents Chemother. March 2005 49: 1101-1105; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Membrane Topology of the Escherichia coli AmpG Permease Required for Recycling of Cell Wall Anhydromuropeptides and AmpC ß-Lactamase Induction Aicha Chahboune, Marc Decaffmeyer, Robert Brasseur, and Bernard Joris Antimicrob. Agents Chemother. March 2005 49: 1145-1149; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Extended-Spectrum Beta-Lactamases among Enterobacter Isolates Obtained in Tel Aviv, Israel Jacob Schlesinger, Shiri Navon-Venezia, Inna Chmelnitsky, Orly Hammer-Münz, Azita Leavitt, Howard S. Gold, Mitchell J. Schwaber, and Yehuda Carmeli Antimicrob. Agents Chemother. March 2005 49: 1150-1156; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Development of Resistance to Six and Four Fluoroquinolones in Mycoplasma pneumoniae and Mycoplasma hominis, Respectively D. Gruson, S. Pereyre, H. Renaudin, A. Charron, C. Bébéar, and C. M. Bébéar Antimicrob. Agents Chemother. March 2005 49: 1190-1193; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Integrons and Transposons on the Salmonella enterica Serovar Typhimurium Virulence Plasmid Laura Villa and Alessandra Carattoli Antimicrob. Agents Chemother. March 2005 49: 1194-1197; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

International Clone of Neisseria meningitidis Serogroup A with Tetracycline Resistance Due to tet(B) Sharon A. Crawford, Kristin R. Fiebelkorn, Jan E. Patterson, and James H. Jorgensen Antimicrob. Agents Chemother. March 2005 49: 1198-1200; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antimicrobial Susceptibility of Shigella sonnei Isolates in Japan and Molecular Analysis of S. sonnei Isolates with Reduced Susceptibility to Fluoroquinolones Kenji Hirose, Jun Terajima, Hidemasa Izumiya, Kazumichi Tamura, Eiji Arakawa, Nobuko Takai, and Haruo Watanabe Antimicrob. Agents Chemother. March 2005 49: 1203-1205; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Deletion of the Multiple-Drug Efflux Pump AcrAB in Escherichia coli Prolongs the Postantibiotic Effect William Stubbings, Julieanne Bostock, Eileen Ingham, and Ian Chopra Antimicrob. Agents Chemother. March 2005 49: 1206-1208; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Efg1 Involved in Drug Resistance by Regulating the Expression of ERG3 in Candida albicans Hsiu-Jung Lo, Jang-Shiun Wang, Chih-Yang Lin, Chia-Geun Chen, Ting-Yin Hsiao, Chia-Tung Hsu, Chia-Li Su, Ming-Ji Fann, Yu-Tai Ching, and Yun-Liang Yang Antimicrob. Agents Chemother. March 2005 49: 1213-1215; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

mecA Is Not Involved in the B-Dependent Switch of the Expression Phenotype of Methicillin Resistance in Staphylococcus epidermidis Johannes K.-M. Knobloch, Sebastian Jäger, Jörn Huck, Matthias A. Horstkotte, and Dietrich Mack Antimicrob. Agents Chemother. March 2005 49: 1216-1219; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Potential Clindamycin Resistance in Clindamycin-Susceptible, Erythromycin-Resistant Staphylococcus aureus: Report of a Clinical Failure Todd P. Levin, Byungse Suh, Peter Axelrod, Allan L. Truant, and Thomas Fekete Antimicrob. Agents Chemother. March 2005 49: 1222-1224; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Disequilibrium in Distribution of Resistance Mutations among Mycobacterium tuberculosis Beijing and Non-Beijing Strains Isolated from Patients in Germany Doris Hillemann, Tanja Kubica, Sabine Rüsch-Gerdes, and Stefan Niemann Antimicrob. Agents Chemother. March 2005 49: 1229-1231; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mutational Analysis of Metronidazole Resistance in Helicobacter pylori Jill M. Moore and Nina R. Salama Antimicrob. Agents Chemother. March 2005 49: 1236-1237; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

New Integron-Associated Gene Cassette Encoding a 3-N-Aminoglycoside Acetyltransferase Renee S. Levings, Sally R. Partridge, Diane Lightfoot, Ruth M. Hall, and Steven P. Djordjevic Antimicrob. Agents Chemother. March 2005 49: 1238-1241; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Experimental Prediction of the Evolution of Ceftazidime Resistance in the CTX-M-2 Extended-Spectrum Beta-Lactamase Kerry J. Welsh, Miriam Barlow, Fred C. Tenover, James W. Biddle, J. Kamile Rasheed, Leigh Ann Clark, and John E. McGowan, Jr. Antimicrob. Agents Chemother. March 2005 49: 1242-1244; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Inducible Metronidazole Resistance and nim Genes in Clinical Bacteroides fragilis Group Isolates Sonja Löfmark, Hong Fang, Maria Hedberg, and Charlotta Edlund Antimicrob. Agents Chemother. March 2005 49: 1253-1256; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Molecular Epidemiology and Prevalence of Macrolide Efflux Genes mef(A) and mef(E) in Streptococcus pneumoniae Obtained in Canada from 1997 to 2002 Aleksandra K. Wierzbowski, Dean Swedlo, Dave Boyd, Michael Mulvey, Kim A. Nichol, Daryl J. Hoban, and George G. Zhanel Antimicrob. Agents Chemother. March 2005 49: 1257-1261; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Monitoring and Characterization of Extended-Spectrum ß-Lactamases in Escherichia coli Strains from Healthy and Sick Animals in Spain in 2003 Laura Briñas, Miguel Angel Moreno, Tirushet Teshager, Yolanda Sáenz, María Concepción Porrero, Lucas Domínguez, and Carmen Torres Antimicrob. Agents Chemother. March 2005 49: 1262-1264; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Mechanisms of Action:

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Induction of Fibronectin Adhesins in Quinolone-Resistant Staphylococcus aureus by Subinhibitory Levels of Ciprofloxacin or by Sigma B Transcription Factor Activity Is Mediated by Two Separate Pathways Dongmei Li, Adriana Renzoni, Tristan Estoppey, Carmelo Bisognano, Patrice Francois, William L. Kelley, Daniel P. Lew, Jacques Schrenzel, and Pierre Vaudaux Antimicrob. Agents Chemother. March 2005 49: 916-924; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Global Expression of Prophage Genes in Escherichia coli O157:H7 Strain EDL933 in Response to Norfloxacin Sylvia Herold, Jutta Siebert, Andrea Huber, and Herbert Schmidt Antimicrob. Agents Chemother. March 2005 49: 931-944; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Small-Molecule Inhibitors of the Budded-to-Hyphal-Form Transition in the Pathogenic Yeast Candida albicans Kurt A. Toenjes, Suzanne M. Munsee, Ashraf S. Ibrahim, Rachel Jeffrey, John E. Edwards, Jr., and Douglas I. Johnson Antimicrob. Agents Chemother. March 2005 49: 963-972; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Biological Characterization of Novel Inhibitors of the Gram-Positive DNA Polymerase IIIC Enzyme Alexander Kuhl, Niels Svenstrup, Christoph Ladel, Michael Otteneder, Annegret Binas, Guido Schiffer, Michael Brands, Thomas Lampe, Karl Ziegelbauer, Helga Rübsamen-Waigmann, Dieter Haebich, and Kerstin Ehlert Antimicrob. Agents Chemother. March 2005 49: 987-995; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Modified Virulence of Antibiotic-Induced Burkholderia pseudomallei Filaments Kang Chen, Guang Wen Sun, Kim Lee Chua, and Yunn-Hwen Gan Antimicrob. Agents Chemother. March 2005 49: 1002-1009; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

c-di-GMP (3'-5'-Cyclic Diguanylic Acid) Inhibits Staphylococcus aureus Cell-Cell Interactions and Biofilm Formation David K. R. Karaolis, Mohammed H. Rashid, Rajanna Chythanya, Wensheng Luo, Mamoru Hyodo, and Yoshihiro Hayakawa Antimicrob. Agents Chemother. March 2005 49: 1029-1038; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Simocyclinone D8, an Inhibitor of DNA Gyrase with a Novel Mode of Action Ruth H. Flatman, Alison J. Howells, Lutz Heide, Hans-Peter Fiedler, and Anthony Maxwell Antimicrob. Agents Chemother. March 2005 49: 1093-1100; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Telavancin, a Multifunctional Lipoglycopeptide, Disrupts both Cell Wall Synthesis and Cell Membrane Integrity in Methicillin-Resistant Staphylococcus aureus Deborah L. Higgins, Ray Chang, Dmitri V. Debabov, Joey Leung, Terry Wu, Kevin M. Krause, Erik Sandvik, Jeffrey M. Hubbard, Koné Kaniga, Donald E. Schmidt, Jr., Qiufeng Gao, Robert T. Cass, Dane E. Karr, Bret M. Benton, and Patrick P. Humphrey Antimicrob. Agents Chemother. March 2005 49: 1127-1134; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antimalarial Activities and Therapeutic Properties of Febrifugine Analogs Suping Jiang, Qiang Zeng, Montip Gettayacamin, Anchalee Tungtaeng, Srisombat Wannaying, Apassorn Lim, Pranee Hansukjariya, Christopher O. Okunji, Shuren Zhu, and Daohe Fang Antimicrob. Agents Chemother. March 2005 49: 1169-1176; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Antiviral Agents:

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Single-Dose Pharmacokinetics and Metabolism of [14C]Remofovir in Rats and Cynomolgus Monkeys Chin-Chung Lin, Christine Xu, Nanqun Zhu, David Lourenco, and Li-Tain Yeh Antimicrob. Agents Chemother. March 2005 49: 925-930; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mechanism of Action of T-705 against Influenza Virus Yousuke Furuta, Kazumi Takahashi, Masako Kuno-Maekawa, Hidehiro Sangawa, Sayuri Uehara, Kyo Kozaki, Nobuhiko Nomura, Hiroyuki Egawa, and Kimiyasu Shiraki Antimicrob. Agents Chemother. March 2005 49: 981-986; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antiadenovirus Activities of Several Classes of Nucleoside and Nucleotide Analogues L. Naesens, L. Lenaerts, G. Andrei, R. Snoeck, D. Van Beers, Antonin Holy, Jan Balzarini, and Erik De Clercq Antimicrob. Agents Chemother. March 2005 49: 1010-1016; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activity and Mechanism of Action of Methylenecyclopropane Analogs of Nucleosides against Herpesvirus Replication Earl R. Kern, Nicole L. Kushner, Caroll B. Hartline, Stephanie L. Williams-Aziz, Emma A. Harden, Shaoman Zhou, Jiri Zemlicka, and Mark N. Prichard Antimicrob. Agents Chemother. March 2005 49: 1039-1045; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Herpes Simplex Virus Thymidine Kinase Mutations Associated with Resistance to Acyclovir: a Site-Directed Mutagenesis Study E. Frobert, T. Ooka, J. C. Cortay, B. Lina, D. Thouvenot, and F. Morfin Antimicrob. Agents Chemother. March 2005 49: 1055-1059; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Susceptibilities of Several Clinical Varicella-Zoster Virus (VZV) Isolates and Drug-Resistant VZV Strains to Bicyclic Furano Pyrimidine Nucleosides Graciela Andrei, Rebecca Sienaert, Chris McGuigan, Erik De Clercq, Jan Balzarini, and Robert Snoeck Antimicrob. Agents Chemother. March 2005 49: 1081-1086; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Orally Active Antiviral Tripeptide Glycyl-Prolyl-Glycinamide Is Activated by CD26 (Dipeptidyl Peptidase IV) before Transport across the Intestinal Epithelium Ina Hubatsch, Lucia Lazorova, Anders Vahlne, and Per Artursson Antimicrob. Agents Chemother. March 2005 49: 1087-1092; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Emergence and Evolution of Enfuvirtide Resistance following Long-Term Therapy Involves Heptad Repeat 2 Mutations within gp41 L. Xu, A. Pozniak, A. Wildfire, S. A. Stanfield-Oakley, S. M. Mosier, D. Ratcliffe, J. Workman, A. Joall, R. Myers, E. Smit, P. A. Cane, M. L. Greenberg, and D. Pillay Antimicrob. Agents Chemother. March 2005 49: 1113-1119; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Alpha Interferon and Ribavirin Combination Therapy of Chronic Hepatitis D Sabahattin Kaymakoglu, Cetin Karaca, Kadir Demir, Sule Poturoglu, Ahmet Danalioglu, Selim Badur, Murvet Bozaci, Fatih Besisik, Yilmaz Cakaloglu, and Atilla Okten Antimicrob. Agents Chemother. March 2005 49: 1135-1138; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activity of Structurally Diverse Nucleoside Analogs against Human Immunodeficiency Virus Type 1 with the K65R Mutation in Reverse Transcriptase Urvi M. Parikh, Dianna L. Koontz, Chung K. Chu, Raymond F. Schinazi, and John W. Mellors Antimicrob. Agents Chemother. March 2005 49: 1139-1144; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Novel Acyclic Nucleoside Phosphonate Analogues with Potent Anti-Hepatitis B Virus Activities C. Ying, A. Holy, D. Hocková, Z. Havlas, E. De Clercq, and J. Neyts Antimicrob. Agents Chemother. March 2005 49: 1177-1180; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Efficacy and Toxicity of Zinc Salts as Candidate Topical Microbicides against Vaginal Herpes Simplex Virus Type 2 Infection Nigel Bourne, Rachael Stegall, Raquel Montano, Michael Meador, Lawrence R. Stanberry, and Gregg N. Milligan Antimicrob. Agents Chemother. March 2005 49: 1181-1183; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Clinical Therapeutics:

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Phase I Evaluation of the Safety and Pharmacokinetics of Murine-Derived Anticryptococcal Antibody 18B7 in Subjects with Treated Cryptococcal Meningitis Robert A. Larsen, Peter G. Pappas, John Perfect, Judith A. Aberg, Arturo Casadevall, Gretchen A. Cloud, Robert James, Scott Filler, and William E. Dismukes Antimicrob. Agents Chemother. March 2005 49: 952-958; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Inhaled Nitric Oxide Treatment of Patients with Pulmonary Tuberculosis Evidenced by Positive Sputum Smears Richard Long, Richard Jones, James Talbot, Irvin Mayers, James Barrie, Michael Hoskinson, and Bruce Light Antimicrob. Agents Chemother. March 2005 49: 1209-1212; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Pharmacology:

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Open-Label, Dose Escalation Study of the Safety and Pharmacokinetic Profile of Tefibazumab in Healthy Volunteers Sandra Reilley, Eric Wenzel, Laurie Reynolds, Beth Bennett, Joseph M. Patti, and Seth Hetherington Antimicrob. Agents Chemother. March 2005 49: 959-962; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Differential Bidirectional Transfer of Indinavir in the Isolated Perfused Human Placenta Sreeja Sudhakaran, Hany Ghabrial, Roger L. Nation, David C. M. Kong, Neil M. Gude, Peter W. Angus, and Craig R. Rayner Antimicrob. Agents Chemother. March 2005 49: 1023-1028; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pharmacokinetics of Gatifloxacin in Infants and Children Edmund V. Capparelli, Michael D. Reed, John S. Bradley, Gregory L. Kearns, Richard F. Jacobs, Bharat D. Damle, Jeffrey L. Blumer, and Dennis M. Grasela Antimicrob. Agents Chemother. March 2005 49: 1106-1112; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Letters:

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Hybrid tet Genes and tet Gene Nomenclature: Request for Opinion Thad B. Stanton, Samuel B. Humphrey, Karen P. Scott, and Harry J. Flint Antimicrob. Agents Chemother. March 2005 49: 1265-1266; [Full Text] [PDF] [Reprints and Permissions]

Evolution of Transposons Containing blaTEM Genes Sally R. Partridge and Ruth M. Hall Antimicrob. Agents Chemother. March 2005 49: 1267-1268; [Full Text] [PDF] [Reprints and Permissions]

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Errata:

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Antifungal Activities of R-135853, a Sordarin Derivative, in Experimental Candidiasis in Mice Yasuki Kamai, Masayo Kakuta, Takahiro Shibayama, Takashi Fukuoka, and Shogo Kuwahara Antimicrob. Agents Chemother. March 2005 49: 1269 [Full Text] [PDF] [Reprints and Permissions]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.