AAC -- Table of Contents (April 1 2005, 49 [4])

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Contents: April 2005, Volume 49, Issue 4

       Minireviews

       Pharmacology

       Mechanisms of Resistance

       Susceptibility

       Mechanisms of Action

       Clinical Therapeutics

       Experimental Therapeutics

       Antiviral Agents

       Biologic Response Modifiers

       Chemistry; Biosynthesis

       Letters

Other Issues

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Table of Contents

[Index by Author]

To see an article, click its [Full Text], [Abstract] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

Minireviews:

Molecular Detection of the Macrolide Efflux Gene: To Discriminate or Not To Discriminate between mef(A) and mef(E)
Corné H. W. Klaassen and Johan W. Mouton
Antimicrob. Agents Chemother. April 2005 49: 1271-1278;
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Pharmacology:

Accumulation and Oriented Transport of Ampicillin in Caco-2 Cells from Its Pivaloyloxymethylester Prodrug, Pivampicillin
Hugues Chanteux, Françoise Van Bambeke, Marie-Paule Mingeot-Leclercq, and Paul M. Tulkens
Antimicrob. Agents Chemother. April 2005 49: 1279-1288;
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Pharmacokinetic and Maximum Tolerated Dose Study of Micafungin in Combination with Fluconazole versus Fluconazole Alone for Prophylaxis of Fungal Infections in Adult Patients Undergoing a Bone Marrow or Peripheral Stem Cell Transplant
J. Hiemenz, P. Cagnoni, D. Simpson, S. Devine, N. Chao, J. Keirns, W. Lau, D. Facklam, and D. Buell
Antimicrob. Agents Chemother. April 2005 49: 1331-1336;
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Pharmacokinetics of Oral Doxycycline during Combination Treatment of Severe Falciparum Malaria
Paul N. Newton, Jean-François Chaulet, Alan Brockman, Wirongrong Chierakul, Arjen Dondorp, Ronatrai Ruangveerayuth, Sornchai Looareesuwan, Cyril Mounier, and Nicholas J. White
Antimicrob. Agents Chemother. April 2005 49: 1622-1625;
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Pharmacokinetic Profile of Tigecycline in Serum and Skin Blister Fluid of Healthy Subjects after Multiple Intravenous Administrations
Heather K. Sun, Christine T. Ong, Ambreen Umer, Dawn Harper, Steven Troy, Charles H. Nightingale, and David P. Nicolau
Antimicrob. Agents Chemother. April 2005 49: 1629-1632;
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Levofloxacin and Ciprofloxacin Decrease Procainamide and N-Acetylprocainamide Renal Clearances
Larry A. Bauer, Douglas J. Black, Jennifer S. Lill, Julie Garrison, Vidmantas A. Raisys, and Thomas M. Hooton
Antimicrob. Agents Chemother. April 2005 49: 1649-1651;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Effects of Age and Sex on Single-Dose Pharmacokinetics of Tigecycline in Healthy Subjects
Gopal Muralidharan, Richard J. Fruncillo, Marlynne Micalizzi, Donald G. Raible, and Steven M. Troy
Antimicrob. Agents Chemother. April 2005 49: 1656-1659;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mechanisms of Resistance:

Evidence for Multiple-Antibiotic Resistance in Campylobacter jejuni Not Mediated by CmeB or CmeF
Lilian Pumbwe, Luke P. Randall, Martin J. Woodward, and Laura J. V. Piddock
Antimicrob. Agents Chemother. April 2005 49: 1289-1293;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Reduced Azole Susceptibility in Genotype 3 Candida dubliniensis Isolates Associated with Increased CdCDR1 and CdCDR2 Expression
Emmanuelle Pinjon, Colin J. Jackson, Steven L. Kelly, Dominique Sanglard, Gary Moran, David C. Coleman, and Derek J. Sullivan
Antimicrob. Agents Chemother. April 2005 49: 1312-1318;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

bla_CTX-M Genes in Clinical Salmonella Isolates Recovered from Humans in England and Wales from 1992 to 2003
M. Batchelor, K. Hopkins, E. J. Threlfall, F. A. Clifton-Hadley, A. D. Stallwood, R. H. Davies, and E. Liebana
Antimicrob. Agents Chemother. April 2005 49: 1319-1322;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Successive Emergence of Enterobacter aerogenes Strains Resistant to Imipenem and Colistin in a Patient
Aurélie Thiolas, Claude Bollet, Bernard La Scola, Didier Raoult, and Jean-Marie Pagès
Antimicrob. Agents Chemother. April 2005 49: 1354-1358;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Silencing of Glycopeptide Resistance in Enterococcus faecalis BM4405 by Novobiocin
Lorena Abadía Patiño, Marc Chippaux, Patrice Courvalin, and Bruno Périchon
Antimicrob. Agents Chemother. April 2005 49: 1419-1425;
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Compensatory Adaptation to the Loss of Biological Fitness Associated with Acquisition of Fusidic Acid Resistance in Staphylococcus aureus
Silke Besier, Albrecht Ludwig, Volker Brade, and Thomas A. Wichelhaus
Antimicrob. Agents Chemother. April 2005 49: 1426-1431;
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Acquisition of Resistance to Carbapenems in Multidrug-Resistant Clinical Strains of Acinetobacter baumannii: Natural Insertional Inactivation of a Gene Encoding a Member of a Novel Family of ß-Barrel Outer Membrane Proteins
María A. Mussi, Adriana S. Limansky, and Alejandro M. Viale
Antimicrob. Agents Chemother. April 2005 49: 1432-1440;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Topoisomerase I Amino Acid Substitutions, Gly185Arg and Asp325Glu, Confer Camptothecin Resistance in Leishmania donovani
Jean-François Marquis, Isabelle Hardy, and Martin Olivier
Antimicrob. Agents Chemother. April 2005 49: 1441-1446;
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Molecular Analysis of Isoniazid-Resistant Mycobacterium tuberculosis Isolates from England and Wales Reveals the Phylogenetic Significance of the ahpC –46A Polymorphism
L. V. Baker, T. J. Brown, O. Maxwell, A. L. Gibson, Z. Fang, M. D. Yates, and F. A. Drobniewski
Antimicrob. Agents Chemother. April 2005 49: 1455-1464;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

A Helicobacter pylori TolC Efflux Pump Confers Resistance to Metronidazole
Karin van Amsterdam, Aldert Bart, and Arie van der Ende
Antimicrob. Agents Chemother. April 2005 49: 1477-1482;
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Phenotypic Tolerance: Antibiotic Enrichment of Noninherited Resistance in Bacterial Populations
C. Wiuff, R. M. Zappala, R. R. Regoes, K. N. Garner, F. Baquero, and B. R. Levin
Antimicrob. Agents Chemother. April 2005 49: 1483-1494;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Cloning, Sequencing, and Characterization of the SdeAB Multidrug Efflux Pump of Serratia marcescens
Ayush Kumar and Elizabeth A. Worobec
Antimicrob. Agents Chemother. April 2005 49: 1495-1501;
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Molecular Mechanisms by Which rRNA Mutations Confer Resistance to Clindamycin
Jacob Poehlsgaard, Peter Pfister, Erik C. Böttger, and Stephen Douthwaite
Antimicrob. Agents Chemother. April 2005 49: 1553-1555;
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Penicillin-Binding Proteins in the Pathogenic Intestinal Spirochete Brachyspira pilosicoli
Rohana P. Dassanayake, Gautam Sarath, and Gerald E. Duhamel
Antimicrob. Agents Chemother. April 2005 49: 1561-1563;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Novel TEM-Type Extended-Spectrum ß-Lactamase, TEM-134, in a Citrobacter koseri Clinical Isolate
Mariagrazia Perilli, Claudia Mugnaioli, Francesco Luzzaro, Marianna Fiore, Stefania Stefani, Gian Maria Rossolini, and Gianfranco Amicosante
Antimicrob. Agents Chemother. April 2005 49: 1564-1566;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

CTX-M-10 Linked to a Phage-Related Element Is Widely Disseminated among Enterobacteriaceae in a Spanish Hospital
Antonio Oliver, Teresa M. Coque, Diana Alonso, Aránzazu Valverde, Fernando Baquero, and Rafael Cantón
Antimicrob. Agents Chemother. April 2005 49: 1567-1571;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Occurrence of CTX-M-3, CTX-M-15, CTX-M-14, and CTX-M-9 Extended-Spectrum ß-Lactamases in Enterobacteriaceae Clinical Isolates in Korea
Jungmin Kim, Yu-Mi Lim, Young-Sook Jeong, and Sung-Yong Seol
Antimicrob. Agents Chemother. April 2005 49: 1572-1575;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Excision of Nucleoside Analogs from DNA by p53 Protein, a Potential Cellular Mechanism of Resistance to Inhibitors of Human Immunodeficiency Virus Type 1 Reverse Transcriptase
Mary Bakhanashvili, Elena Novitsky, Ethan Rubinstein, Itzchak Levy, and Galia Rahav
Antimicrob. Agents Chemother. April 2005 49: 1576-1579;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Capsule Homology Does Not Increase the Frequency of Transformation of Linked Penicillin Binding Proteins PBP 1a and PBP 2x in Streptococcus pneumoniae
Krzysztof Trzcinski, Adam MacNeil, Keith P. Klugman, and Marc Lipsitch
Antimicrob. Agents Chemother. April 2005 49: 1591-1592;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Functional Characterization of OXA-57, a Class D ß-Lactamase from Burkholderia pseudomallei
Karen E. Keith, Petra C. Oyston, Ben Crossett, Neil F. Fairweather, Richard W. Titball, Timothy R. Walsh, and Katherine A. Brown
Antimicrob. Agents Chemother. April 2005 49: 1639-1641;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Genetic Basis of Antibiotic Resistance in Clinical Isolates of Streptococcus gallolyticus (Streptococcus bovis)
Roland Leclercq, Corinne Huet, Mélanie Picherot, Patrick Trieu-Cuot, and Claire Poyart
Antimicrob. Agents Chemother. April 2005 49: 1646-1648;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Susceptibility:

In Vitro Susceptibility Testing of Borrelia burgdorferi Sensu Lato Isolates Cultured from Patients with Erythema Migrans before and after Antimicrobial Chemotherapy
Klaus-Peter Hunfeld, Eva Ruzic-Sabljic, Douglas E. Norris, Peter Kraiczy, and Franc Strle
Antimicrob. Agents Chemother. April 2005 49: 1294-1301;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Is In Vitro Antibiotic Combination More Effective than Single-Drug Therapy against Anthrax?
Abed Athamna, Muhammad Athamna, Aburashed Nura, Eli Shlyakov, Darrin J. Bast, David Farrell, and Ethan Rubinstein
Antimicrob. Agents Chemother. April 2005 49: 1323-1325;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Bactericidal and Antiendotoxic Properties of Short Cationic Peptides Derived from a Snake Venom Lys49 Phospholipase A₂
Carlos Santamaría, Silda Larios, Steve Quirós, Javier Pizarro-Cerda, Jean-Pierre Gorvel, Bruno Lomonte, and Edgardo Moreno
Antimicrob. Agents Chemother. April 2005 49: 1340-1345;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Testing of the In Vitro Susceptibilities of Madurella mycetomatis to Six Antifungal Agents by Using the Sensititre System in Comparison with a Viability-Based 2,3-Bis(2-Methoxy-4-Nitro-5-Sulfophenyl)-5- [(Phenylamino)Carbonyl]-2H-Tetrazolium Hydroxide (XTT) Assay and a Modified NCCLS Method
Wendy W. J. van de Sande, Ad Luijendijk, Abdalla O. A. Ahmed, Irma A. J. M. Bakker-Woudenberg, and Alex van Belkum
Antimicrob. Agents Chemother. April 2005 49: 1364-1368;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Phototargeting Oral Black-Pigmented Bacteria
Nikolaos S. Soukos, Sovanda Som, Abraham D. Abernethy, Karriann Ruggiero, Joshua Dunham, Chul Lee, Apostolos G. Doukas, and J. Max Goodson
Antimicrob. Agents Chemother. April 2005 49: 1391-1396;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Comparative Antimicrobial Characterization of LBM415 (NVP PDF-713), a New Peptide Deformylase Inhibitor of Clinical Importance
Thomas R. Fritsche, Helio S. Sader, Roy Cleeland, and Ronald N. Jones
Antimicrob. Agents Chemother. April 2005 49: 1468-1476;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Effects of Spectinomycin and Ceftriaxone Alone or in Combination with Other Antibiotics against Chlamydia trachomatis
Shuxian Shang, Longqing Xia, Mingying Zhong, Jinping Zhang, Jianbin Zhao, Xiangdong Gong, David Mabey, and Qianqiu Wang
Antimicrob. Agents Chemother. April 2005 49: 1584-1586;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Synergistic Activities of Fluconazole and Voriconazole with Terbinafine against Four Candida Species Determined by Checkerboard, Time-Kill, and Etest Methods
Emilia Cantón, Javier Pemán, Miguel Gobernado, Angel Viudes, and Ana Espinel-Ingroff
Antimicrob. Agents Chemother. April 2005 49: 1593-1596;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antifungal Activity of Flocculosin, a Novel Glycolipid Isolated from Pseudozyma flocculosa
Benjamin Mimee, Caroline Labbé, René Pelletier, and Richard R. Bélanger
Antimicrob. Agents Chemother. April 2005 49: 1597-1599;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Sensititre YeastOne Caspofungin Susceptibility Testing of Candida Clinical Isolates: Correlation with Results of NCCLS M27-A2 Multicenter Study
Emilia Cantón, Javier Pemán, Miguel Gobernado, Elena Álvarez, Fernando Baquero, Ramón Cisterna, Joaquina Gil, Estrella Martín-Mazuelos, Carmen Rubio, Aurora Sánchez-Sousa, and Carmen Serrano
Antimicrob. Agents Chemother. April 2005 49: 1604-1607;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mutant Prevention Concentrations of ABT-492, Levofloxacin, Moxifloxacin, and Gatifloxacin against Three Common Respiratory Pathogens
Elizabeth D. Hermsen, Laurie B. Hovde, George N. Konstantinides, and John C. Rotschafer
Antimicrob. Agents Chemother. April 2005 49: 1633-1635;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Presence of Tetracycline Resistance Determinants and Susceptibility to Tigecycline and Minocycline
Ad C. Fluit, Alice Florijn, Jan Verhoef, and Dana Milatovic
Antimicrob. Agents Chemother. April 2005 49: 1636-1638;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mechanisms of Action:

Glycerol Monolaurate Inhibits Virulence Factor Production in Bacillus anthracis
Sara M. Vetter and Patrick M. Schlievert
Antimicrob. Agents Chemother. April 2005 49: 1302-1305;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Azithromycin Exhibits Bactericidal Effects on Pseudomonas aeruginosa through Interaction with the Outer Membrane
Yoshifumi Imamura, Yasuhito Higashiyama, Kazunori Tomono, Koichi Izumikawa, Katsunori Yanagihara, Hideaki Ohno, Yoshitsugu Miyazaki, Yoichi Hirakata, Yohei Mizuta, Jun-ichi Kadota, Barbara H. Iglewski, and Shigeru Kohno
Antimicrob. Agents Chemother. April 2005 49: 1377-1380;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Susceptibility to Antibiotics and ß-Lactamase Induction in Murein Hydrolase Mutants of Escherichia coli
Dorota Korsak, Sylvia Liebscher, and Waldemar Vollmer
Antimicrob. Agents Chemother. April 2005 49: 1404-1409;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Scintillation Proximity Assay for Inhibitors of Escherichia coli MurG and, Optionally, MraY
Sudha Ravishankar, Vidya Prasanna Kumar, B. Chandrakala, Ramesh K. Jha, Suresh M. Solapure, and Sunita M. de Sousa
Antimicrob. Agents Chemother. April 2005 49: 1410-1418;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Photodynamic Effects of Novel XF Porphyrin Derivatives on Prokaryotic and Eukaryotic Cells
T. Maisch, C. Bosl, R.-M. Szeimies, N. Lehn, and C. Abels
Antimicrob. Agents Chemother. April 2005 49: 1542-1552;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Different Rifampin Sensitivities of Escherichia coli and Mycobacterium tuberculosis RNA Polymerases Are Not Explained by the Difference in the ß-Subunit Rifampin Regions I and II
N. Zenkin, A. Kulbachinskiy, I. Bass, and V. Nikiforov
Antimicrob. Agents Chemother. April 2005 49: 1587-1590;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Cloning, Characterization, and Expression Analysis of Hepcidin Gene from Red Sea Bream (Chrysophrys major)
Song-Lin Chen, Mei-Yu Xu, Xiang-Shan Ji, Guo-Cai Yu, and Yang Liu
Antimicrob. Agents Chemother. April 2005 49: 1608-1612;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antibiotic Tolerance Induced by Lactoferrin in Clinical Pseudomonas aeruginosa Isolates from Cystic Fibrosis Patients
María T. Andrés, Mónica Viejo-Diaz, Francisco Pérez, and José F. Fierro
Antimicrob. Agents Chemother. April 2005 49: 1613-1616;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Secretion of Proinflammatory Cytokines and Chemokines during Amphotericin B Exposure Is Mediated by Coactivation of Toll-Like Receptors 1 and 2
Raymund R. Razonable, Martin Henault, Linda N. Lee, Carmen Laethem, Paul A. Johnston, Harold L. Watson, and Carlos V. Paya
Antimicrob. Agents Chemother. April 2005 49: 1617-1621;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Clinical Therapeutics:

Pseudomonas aeruginosa Bloodstream Infection: Importance of Appropriate Initial Antimicrobial Treatment
Scott T. Micek, Ann E. Lloyd, David J. Ritchie, Richard M. Reichley, Victoria J. Fraser, and Marin H. Kollef
Antimicrob. Agents Chemother. April 2005 49: 1306-1311;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Comparison of the Pharmacodynamics of Meropenem in Patients with Ventilator-Associated Pneumonia following Administration by 3-Hour Infusion or Bolus Injection
Sutep Jaruratanasirikul, Somchai Sriwiriyajan, and Jarurat Punyo
Antimicrob. Agents Chemother. April 2005 49: 1337-1339;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro and In Vivo Activities of Macrolide Derivatives against Mycobacterium tuberculosis
Kanakeshwari Falzari, Zhaohai Zhu, Dahua Pan, Huiwen Liu, Poonpilas Hongmanee, and Scott G. Franzblau
Antimicrob. Agents Chemother. April 2005 49: 1447-1454;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Effect of Mupirocin Treatment on Nasal, Pharyngeal, and Perineal Carriage of Staphylococcus aureus in Healthy Adults
Heiman F. L. Wertheim, Jeroen Verveer, Hélène A. M. Boelens, Alex van Belkum, Henri A. Verbrugh, and Magreet C. Vos
Antimicrob. Agents Chemother. April 2005 49: 1465-1467;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Impact of Clarithromycin Resistance on Eradication of Helicobacter pylori in Infected Adults
Jong Hwa Lee, Ji-Hyun Shin, Im Hwan Roe, Seung Ghyu Sohn, Jung Hun Lee, Geun Ho Kang, Han-Ki Lee, Byeong Chul Jeong, and Sang Hee Lee
Antimicrob. Agents Chemother. April 2005 49: 1600-1603;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Experimental Therapeutics:

Activity of Hoechst 33258 against Pneumocystis carinii f. sp. muris, Candida albicans, and Candida dubliniensis
Matthew D. Disney, Ruth Stephenson, Terry W. Wright, Constantine G. Haidaris, Douglas H. Turner, and Francis Gigliotti
Antimicrob. Agents Chemother. April 2005 49: 1326-1330;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Topical Caspofungin for Treatment of Keratitis Caused by Candida albicans in a Rabbit Model
David Goldblum, Beatrice E. Frueh, Gian-Marco Sarra, Konstantinos Katsoulis, and Stefan Zimmerli
Antimicrob. Agents Chemother. April 2005 49: 1359-1363;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Efficacy of Caspofungin against Central Nervous System Aspergillus fumigatus Infection in Mice Determined by TaqMan PCR and CFU Methods
Gaurav Singh, Jackie Imai, Karl V. Clemons, and David A. Stevens
Antimicrob. Agents Chemother. April 2005 49: 1369-1376;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Efficacy of Ciprofloxacin-Releasing Bioabsorbable Osteoconductive Bone Defect Filler for Treatment of Experimental Osteomyelitis Due to Staphylococcus aureus
Jyri K. Koort, Tatu J. Mäkinen, Esa Suokas, Minna Veiranto, Jari Jalava, Juhani Knuuti, Pertti Törmälä, and Hannu T. Aro
Antimicrob. Agents Chemother. April 2005 49: 1502-1508;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Treatment with Benznidazole during the Chronic Phase of Experimental Chagas' Disease Decreases Cardiac Alterations
Simone Garcia, Carolina O. Ramos, Juliana F. V. Senra, Fabio Vilas-Boas, Maurício M. Rodrigues, Antonio C. Campos-de-Carvalho, Ricardo Ribeiro-dos-Santos, and Milena B. P. Soares
Antimicrob. Agents Chemother. April 2005 49: 1521-1528;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Comparative Efficacies of TAK-187, a Long-Lasting Ergosterol Biosynthesis Inhibitor, and Benznidazole in Preventing Cardiac Damage in a Murine Model of Chagas' Disease
Milagros Corrales, Rubén Cardozo, María Asunción Segura, Julio A. Urbina, and Miguel Angel Basombrío
Antimicrob. Agents Chemother. April 2005 49: 1556-1560;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Efficacy and Safety of Generic Amphotericin B in Experimental Pulmonary Aspergillosis
Vidmantas Petraitis, Ruta Petraitiene, Pengxin Lin, Karim Calis, Amy M. Kelaher, Heidi A. Muray, Christine Mya-San, Diana Mickiene, John Bacher, and Thomas J. Walsh
Antimicrob. Agents Chemother. April 2005 49: 1642-1645;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antiviral Agents:

Development of a Cell-Based High-Throughput Specificity Screen Using a Hepatitis C Virus-Bovine Viral Diarrhea Virus Dual Replicon Assay
Donald R. O'Boyle, II, Peter T. Nower, Julie A. Lemm, Lourdes Valera, Jin-Hua Sun, Karen Rigat, Richard Colonno, and Min Gao
Antimicrob. Agents Chemother. April 2005 49: 1346-1353;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Development of Cell-Based Assays for In Vitro Characterization of Hepatitis C Virus NS3/4A Protease Inhibitors
Victoria Chung, Anthony R. Carroll, Norman M. Gray, Nigel R. Parry, Pia A. Thommes, K. Claire Viner, and Eric A. D'Souza
Antimicrob. Agents Chemother. April 2005 49: 1381-1390;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Comparative Safety Evaluation of the Candidate Vaginal Microbicide C31G
Bradley J. Catalone, Tina M. Kish-Catalone, Elizabeth B. Neely, Lynn R. Budgeon, Mary L. Ferguson, Catherine Stiller, Shendra R. Miller, Daniel Malamud, Fred C. Krebs, Mary K. Howett, and Brian Wigdahl
Antimicrob. Agents Chemother. April 2005 49: 1509-1520;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Early Selection of a New UL97 Mutant with a Severe Defect of Ganciclovir Phosphorylation after Valaciclovir Prophylaxis and Short-Term Ganciclovir Therapy in a Renal Transplant Recipient
Sébastien Hantz, Detlef Michel, Anne-Marie Fillet, Vincent Guigonis, Gaël Champier, Marie-Christine Mazeron, Albert Bensman, François Denis, Thomas Mertens, Axelle Dehee, and Sophie Alain
Antimicrob. Agents Chemother. April 2005 49: 1580-1583;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Role of P-Glycoprotein in Distribution of Nelfinavir across the Blood-Mammary Tissue Barrier and Blood-Brain Barrier
Jeffrey E. Edwards, Jane Alcorn, Juoko Savolainen, Bradley D. Anderson, and Patrick J. McNamara
Antimicrob. Agents Chemother. April 2005 49: 1626-1628;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Biologic Response Modifiers:

Differential Expression of Cytokines and Chemokines in Human Monocytes Induced by Lipid Formulations of Amphotericin B
M. Simitsopoulou, E. Roilides, J. Dotis, M. Dalakiouridou, F. Dudkova, E. Andreadou, and T. J. Walsh
Antimicrob. Agents Chemother. April 2005 49: 1397-1403;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Chemistry; Biosynthesis:

Expression of ccaR, Encoding the Positive Activator of Cephamycin C and Clavulanic Acid Production in Streptomyces clavuligerus, Is Dependent on bldG
Dawn R. D. Bignell, Kapil Tahlan, Kimberley R. Colvin, Susan E. Jensen, and Brenda K. Leskiw
Antimicrob. Agents Chemother. April 2005 49: 1529-1541;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro and In Vivo Cytotoxicities and Antileishmanial Activities of Thymol and Hemisynthetic Derivatives
Sara Robledo, Edison Osorio, Diana Muñoz, Luz Marina Jaramillo, Adriana Restrepo, Gabriel Arango, and Iván Vélez
Antimicrob. Agents Chemother. April 2005 49: 1652-1655;
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Letters:

Alteration in the GyrA Subunit of DNA Gyrase and the ParC Subunit of Topoisomerase IV in Quinolone-Resistant Shigella dysenteriae Serotype 1 Clinical Isolates from Kolkata, India
Shanta Dutta, Yoshiaki Kawamura, Takayuki Ezaki, Gopinath Balakrish Nair, Ken-Ichiro Iida, and Shin-Ichi Yoshida
Antimicrob. Agents Chemother. April 2005 49: 1660-1661;
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Rollback of Salmonella enterica Serotype Typhi Resistance to Chloramphenicol and Other Antimicrobials in Kolkata, India
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