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Minireviews:

Mark A. Wainberg, Bluma G. Brenner, and Dan Turner

Changing Patterns in the Selection of Viral Mutations among Patients Receiving Nucleoside and Nucleotide Drug Combinations Directed against Human Immunodeficiency Virus Type 1 Reverse Transcriptase
Antimicrob. Agents Chemother. 2005 49: 1671-1678. [Full Text] [PDF]  

Experimental Therapeutics:

Denise C. Arruda, Fabio Luiz D'Alexandri, Alejandro M. Katzin, and Silvia R. B. Uliana

Antileishmanial Activity of the Terpene Nerolidol
Antimicrob. Agents Chemother. 2005 49: 1679-1687. [Abstract] [Full Text] [PDF]  

Hail M. Al-Abdely, Laura K. Najvar, Rosie Bocanegra, and John R. Graybill

Antifungal Therapy of Experimental Cerebral Phaeohyphomycosis Due to Cladophialophora bantiana
Antimicrob. Agents Chemother. 2005 49: 1701-1707. [Abstract] [Full Text] [PDF]  

Brent M. Booker, Patrick F. Smith, Alan Forrest, Julie Bullock, Pamela Kelchlin, Sujata M. Bhavnani, Ronald N. Jones, and Paul G. Ambrose

Application of an In Vitro Infection Model and Simulation for Reevaluation of Fluoroquinolone Breakpoints for Salmonella enterica Serotype Typhi
Antimicrob. Agents Chemother. 2005 49: 1775-1781. [Abstract] [Full Text] [PDF]  

George G. Zhanel, Christel Johanson, Nancy Laing, Tamiko Hisanaga, Aleksandra Wierzbowski, and Daryl J. Hoban

Pharmacodynamic Activity of Telithromycin at Simulated Clinically Achievable Free-Drug Concentrations in Serum and Epithelial Lining Fluid against Efflux (mefE)-Producing Macrolide- Resistant Streptococcus pneumoniae for Which Telithromycin MICs Vary
Antimicrob. Agents Chemother. 2005 49: 1943-1948. [Abstract] [Full Text] [PDF]  

B. P. Olivieri, D. A. Farias-De-Oliveira, T. C. Araujo-Jorge, and V. Cotta-de-Almeida

Benznidazole Therapy in Trypanosoma cruzi-Infected Mice Blocks Thymic Involution and Apoptosis of CD4⁺CD8⁺ Double-Positive Thymocytes
Antimicrob. Agents Chemother. 2005 49: 1981-1987. [Abstract] [Full Text] [PDF]  

Ruta Petraitiene, Vidmantas Petraitis, Amy M. Kelaher, Alia A. Sarafandi, Diana Mickiene, Andreas H. Groll, Tin Sein, John Bacher, and Thomas J. Walsh

Efficacy, Plasma Pharmacokinetics, and Safety of Icofungipen, an Inhibitor of Candida Isoleucyl-tRNA Synthetase, in Treatment of Experimental Disseminated Candidiasis in Persistently Neutropenic Rabbits
Antimicrob. Agents Chemother. 2005 49: 2084-2092. [Abstract] [Full Text] [PDF]  

Mechanisms of Resistance:

S. A. Ballard, K. K. Pertile, M. Lim, P. D. R. Johnson, and M. L. Grayson

Molecular Characterization of vanB Elements in Naturally Occurring Gut Anaerobes
Antimicrob. Agents Chemother. 2005 49: 1688-1694. [Abstract] [Full Text] [PDF]  

Laurent Poirel, Ludovic Cabanne, Haluk Vahaboglu, and Patrice Nordmann

Genetic Environment and Expression of the Extended-Spectrum ß-Lactamase bla_PER-1 Gene in Gram-Negative Bacteria
Antimicrob. Agents Chemother. 2005 49: 1708-1713. [Abstract] [Full Text] [PDF]  

Josep M. Sierra, Luis Martinez-Martinez, Fernando Vázquez, Ernest Giralt, and Jordi Vila

Relationship between Mutations in the gyrA Gene and Quinolone Resistance in Clinical Isolates of Corynebacterium striatum and Corynebacterium amycolatum
Antimicrob. Agents Chemother. 2005 49: 1714-1719. [Abstract] [Full Text] [PDF]  

Sarah MacPherson, Bassel Akache, Sandra Weber, Xavier De Deken, Martine Raymond, and Bernard Turcotte

Candida albicans Zinc Cluster Protein Upc2p Confers Resistance to Antifungal Drugs and Is an Activator of Ergosterol Biosynthetic Genes
Antimicrob. Agents Chemother. 2005 49: 1745-1752. [Abstract] [Full Text] [PDF]  

Tiffany R. Shultz, Peter A. White, and John W. Tapsall

In Vitro Assessment of the Further Potential for Development of Fluoroquinolone Resistance in Neisseria meningitidis
Antimicrob. Agents Chemother. 2005 49: 1753-1760. [Abstract] [Full Text] [PDF]  

Mara L. Sobel, Didier Hocquet, Lily Cao, Patrick Plesiat, and Keith Poole

Mutations in PA3574 (nalD) Lead to Increased MexAB-OprM Expression and Multidrug Resistance in Laboratory and Clinical Isolates of Pseudomonas aeruginosa
Antimicrob. Agents Chemother. 2005 49: 1782-1786. [Abstract] [Full Text] [PDF]  

W. H. Gaze, N. Abdouslam, P. M. Hawkey, and E. M. H. Wellington

Incidence of Class 1 Integrons in a Quaternary Ammonium Compound-Polluted Environment
Antimicrob. Agents Chemother. 2005 49: 1802-1807. [Abstract] [Full Text] [PDF]  

Elisabete Machado, Rafael Cantón, Fernando Baquero, Juan-Carlos Galán, Azucena Rollán, Luísa Peixe, and Teresa M. Coque

Integron Content of Extended-Spectrum-ß-Lactamase-Producing Escherichia coli Strains over 12 Years in a Single Hospital in Madrid, Spain
Antimicrob. Agents Chemother. 2005 49: 1823-1829. [Abstract] [Full Text] [PDF]  

Rungtip Chuanchuen, Jared B. Gaynor, RoxAnn Karkhoff-Schweizer, and Herbert P. Schweizer

Molecular Characterization of MexL, the Transcriptional Repressor of the mexJK Multidrug Efflux Operon in Pseudomonas aeruginosa
Antimicrob. Agents Chemother. 2005 49: 1844-1851. [Abstract] [Full Text] [PDF]  

Glenn W. Kaatz, Fionnuala McAleese, and Susan M. Seo

Multidrug Resistance in Staphylococcus aureus Due to Overexpression of a Novel Multidrug and Toxin Extrusion (MATE) Transport Protein
Antimicrob. Agents Chemother. 2005 49: 1857-1864. [Abstract] [Full Text] [PDF]  

Fionnuala McAleese, Peter Petersen, Alexey Ruzin, Paul M. Dunman, Ellen Murphy, Steven J. Projan, and Patricia A. Bradford

A Novel MATE Family Efflux Pump Contributes to the Reduced Susceptibility of Laboratory-Derived Staphylococcus aureus Mutants to Tigecycline
Antimicrob. Agents Chemother. 2005 49: 1865-1871. [Abstract] [Full Text] [PDF]  

Anna Baraniak, Janusz Fiett, Agnieszka Mrówka, Jaroslaw Walory, Waleria Hryniewicz, and Marek Gniadkowski

Evolution of TEM-Type Extended-Spectrum ß-Lactamases in Clinical Enterobacteriaceae Strains in Poland
Antimicrob. Agents Chemother. 2005 49: 1872-1880. [Abstract] [Full Text] [PDF]  

John F. Lancashire, Tamsin D. Terry, P. J. Blackall, and Michael P. Jennings

Plasmid-Encoded Tet B Tetracycline Resistance in Haemophilus parasuis
Antimicrob. Agents Chemother. 2005 49: 1927-1931. [Abstract] [Full Text] [PDF]  

Susanna K. P. Lau, Pak-leung Ho, Maria W. S. Li, Hoi-wah Tsoi, Raymond W. H. Yung, Patrick C. Y. Woo, and Kwok-yung Yuen

Cloning and Characterization of a Chromosomal Class C ß-Lactamase and Its Regulatory Gene in Laribacter hongkongensis
Antimicrob. Agents Chemother. 2005 49: 1957-1964. [Abstract] [Full Text] [PDF]  

Francesco Giuliani, Jean-Denis Docquier, Maria Letizia Riccio, Laura Pagani, and Gian Maria Rossolini

OXA-46, a New Class D ß-Lactamase of Narrow Substrate Specificity Encoded by a bla_VIM-1-Containing Integron from a Pseudomonas aeruginosa Clinical Isolate
Antimicrob. Agents Chemother. 2005 49: 1973-1980. [Abstract] [Full Text] [PDF]  

Karima El Fadili, Nadine Messier, Philippe Leprohon, Gaétan Roy, Chantal Guimond, Nathalie Trudel, Nancy G. Saravia, Barbara Papadopoulou, Danielle Légaré, and Marc Ouellette

Role of the ABC Transporter MRPA (PGPA) in Antimony Resistance in Leishmania infantum Axenic and Intracellular Amastigotes
Antimicrob. Agents Chemother. 2005 49: 1988-1993. [Abstract] [Full Text] [PDF]  

Anthony M. Smith, Charles Feldman, Orietta Massidda, Kerrigan McCarthy, Dalu Ndiweni, and Keith P. Klugman

Altered PBP 2A and Its Role in the Development of Penicillin, Cefotaxime, and Ceftriaxone Resistance in a Clinical Isolate of Streptococcus pneumoniae
Antimicrob. Agents Chemother. 2005 49: 2002-2007. [Abstract] [Full Text] [PDF]  

Anna Shore, Angela S. Rossney, Conor T. Keane, Mark C. Enright, and David C. Coleman

Seven Novel Variants of the Staphylococcal Chromosomal Cassette mec in Methicillin-Resistant Staphylococcus aureus Isolates from Ireland
Antimicrob. Agents Chemother. 2005 49: 2070-2083. [Abstract] [Full Text] [PDF]  

Salomon Ohana, Veronique Leflon, Esthel Ronco, Martin Rottman, Didier Guillemot, Sylvie Lortat-Jacob, Pierre Denys, Georges Loubert, Marie-Helène Nicolas-Chanoine, Jean-Louis Gaillard, and Christine Lawrence

Spread of a Klebsiella pneumoniae Strain Producing a Plasmid- Mediated ACC-1 AmpC ß-Lactamase in a Teaching Hospital Admitting Disabled Patients
Antimicrob. Agents Chemother. 2005 49: 2095-2097. [Abstract] [Full Text] [PDF]  

Hiep N'Guyen Trong, Anne-Laure Prunier, and Roland Leclercq

Hypermutable and Fluoroquinolone-Resistant Clinical Isolates of Staphylococcus aureus
Antimicrob. Agents Chemother. 2005 49: 2098-2101. [Abstract] [Full Text] [PDF]  

Nanhua Chen, Danny W. Wilson, Cielo Pasay, David Bell, Laura B. Martin, Dennis Kyle, and Qin Cheng

Origin and Dissemination of Chloroquine-Resistant Plasmodium falciparum with Mutant pfcrt Alleles in the Philippines
Antimicrob. Agents Chemother. 2005 49: 2102-2105. [Abstract] [Full Text] [PDF]  

Benoît Doublet, Stefan Schwarz, Corinna Kehrenberg, and Axel Cloeckaert

Florfenicol Resistance Gene floR Is Part of a Novel Transposon
Antimicrob. Agents Chemother. 2005 49: 2106-2108. [Abstract] [Full Text] [PDF]  

C. Silva-Costa, M. Ramirez, J. Melo-Cristino the Portuguese Surveillance Group for the Study of Respiratory Pathogens

Rapid Inversion of the Prevalences of Macrolide Resistance Phenotypes Paralleled by a Diversification of T and emm Types among Streptococcus pyogenes in Portugal
Antimicrob. Agents Chemother. 2005 49: 2109-2111. [Abstract] [Full Text] [PDF]  

Adam B. Olson, M. Silverman, David A. Boyd, Allison McGeer, Barbara M. Willey, V. Pong-Porter, N. Daneman, and Michael R. Mulvey

Identification of a Progenitor of the CTX-M-9 Group of Extended-Spectrum ß-Lactamases from Kluyvera georgiana Isolated in Guyana
Antimicrob. Agents Chemother. 2005 49: 2112-2115. [Abstract] [Full Text] [PDF]  

G. Garcia-Effron, E. Mellado, A. Gomez-Lopez, L. Alcazar-Fuoli, M. Cuenca-Estrella, and Juan L. Rodriguez-Tudela

Differences in Interactions between Azole Drugs Related to Modifications in the 14- Sterol Demethylase Gene (cyp51A) of Aspergillus fumigatus
Antimicrob. Agents Chemother. 2005 49: 2119-2121. [Abstract] [Full Text] [PDF]  

J. R. Hernández, L. Martínez-Martínez, R. Cantón, T. M. Coque, A. Pascual Spanish Group for Nosocomial Infections (GEIH)

Nationwide Study of Escherichia coli and Klebsiella pneumoniae Producing Extended-Spectrum ß-Lactamases in Spain
Antimicrob. Agents Chemother. 2005 49: 2122-2125. [Abstract] [Full Text] [PDF]  

Ewa Sadowy, Radoslaw Izdebski, Anna Skoczynska, Marek Gniadkowski, and Waleria Hryniewicz

High Genetic Diversity of Ciprofloxacin-Nonsusceptible Isolates of Streptococcus pneumoniae in Poland
Antimicrob. Agents Chemother. 2005 49: 2126-2129. [Abstract] [Full Text] [PDF]  

Jeff Powis, Allison McGeer, Carla Duncan, Ryan Goren, Joyce C. S. de Azavedo, Darrin J. Bast, Sylvia Pong-Porter, Tony Mazzulli, Karen Green, Barbara Willey, and Donald E. Low

Prevalence and Characterization of Invasive Isolates of Streptococcus pyogenes with Reduced Susceptibility to Fluoroquinolones
Antimicrob. Agents Chemother. 2005 49: 2130-2132. [Abstract] [Full Text] [PDF]  

Rungtip Chuanchuen, Takeshi Murata, Naomasa Gotoh, and Herbert P. Schweizer

Substrate-Dependent Utilization of OprM or OpmH by the Pseudomonas aeruginosa MexJK Efflux Pump
Antimicrob. Agents Chemother. 2005 49: 2133-2136. [Abstract] [Full Text] [PDF]  

Pharmacology:

Françoise Van Bambeke, Jennifer Saffran, Marie-Paule Mingeot-Leclercq, and Paul M. Tulkens

Mixed-Lipid Storage Disorder Induced in Macrophages and Fibroblasts by Oritavancin (LY333328), a New Glycopeptide Antibiotic with Exceptional Cellular Accumulation
Antimicrob. Agents Chemother. 2005 49: 1695-1700. [Abstract] [Full Text] [PDF]  

Martina Kinzig-Schippers, Dorota Tomalik-Scharte, Alexander Jetter, Bernhard Scheidel, Verena Jakob, Michael Rodamer, Ingolf Cascorbi, Oxana Doroshyenko, Fritz Sörgel, and Uwe Fuhr

Should We Use N-Acetyltransferase Type 2 Genotyping To Personalize Isoniazid Doses?
Antimicrob. Agents Chemother. 2005 49: 1733-1738. [Abstract] [Full Text] [PDF]  

Thomas C. Dowling, Pierre A. Chavaillaz, David G. Young, Angela Melton-Celsa, Alison O'Brien, Claire Thuning-Roberson, Robert Edelman, and Carol O. Tacket

Phase 1 Safety and Pharmacokinetic Study of Chimeric Murine-Human Monoclonal Antibody cStx2 Administered Intravenously to Healthy Adult Volunteers
Antimicrob. Agents Chemother. 2005 49: 1808-1812. [Abstract] [Full Text] [PDF]  

Clark Chan, Eyas Abu-Raddad, Georg Golor, Hikari Watanabe, Akira Sasaki, Kwee Poo Yeo, Danny Soon, Vikram P. Sinha, Shawn D. Flanagan, Minxia M. He, and Stephen D. Wise

Clinical Pharmacokinetics of Alamifovir and Its Metabolites
Antimicrob. Agents Chemother. 2005 49: 1813-1822. [Abstract] [Full Text] [PDF]  

Wolfgang A. Krueger, Jurgen Bulitta, Martina Kinzig-Schippers, Cornelia Landersdorfer, Ulrike Holzgrabe, Kurt G. Naber, George L. Drusano, and Fritz Sörgel

Evaluation by Monte Carlo Simulation of the Pharmacokinetics of Two Doses of Meropenem Administered Intermittently or as a Continuous Infusion in Healthy Volunteers
Antimicrob. Agents Chemother. 2005 49: 1881-1889. [Abstract] [Full Text] [PDF]  

Antiviral Agents:

Anne-Geneviève Marcelin, Isabelle Cohen-Codar, Martin S. King, Philippe Colson, Emmanuel Guillevic, Diane Descamps, Claire Lamotte, Véronique Schneider, Jacques Ritter, Michel Segondy, Hélène Peigue-Lafeuille, Laurence Morand-Joubert, Anne Schmuck, Annick Ruffault, Pierre Palmer, Marie-Laure Chaix, Vincent Mackiewicz, Véronique Brodard, Jacques Izopet, Jacqueline Cottalorda, Evelyne Kohli, Jean-Pierre Chauvin, Dale J. Kempf, Gilles Peytavin, and Vincent Calvez

Virological and Pharmacological Parameters Predicting the Response to Lopinavir-Ritonavir in Heavily Protease Inhibitor-Experienced Patients
Antimicrob. Agents Chemother. 2005 49: 1720-1726. [Abstract] [Full Text] [PDF]  

Anne-Geneviève Marcelin, Philippe Flandre, Juliette Pavie, Nathalie Schmidely, Marc Wirden, Olivier Lada, Dan Chiche, Jean-Michel Molina, Vincent Calvez the AI454-176 Jaguar Study Team

Clinically Relevant Genotype Interpretation of Resistance to Didanosine
Antimicrob. Agents Chemother. 2005 49: 1739-1744. [Abstract] [Full Text] [PDF]  

Anthony J. Smith, Peter R. Meyer, Deshratn Asthana, Margarita R. Ashman, and Walter A. Scott

Intracellular Substrates for the Primer-Unblocking Reaction by Human Immunodeficiency Virus Type 1 Reverse Transcriptase: Detection and Quantitation in Extracts from Quiescent- and Activated-Lymphocyte Subpopulations
Antimicrob. Agents Chemother. 2005 49: 1761-1769. [Abstract] [Full Text] [PDF]  

Shuwen Liu, Hong Lu, A. Robert Neurath, and Shibo Jiang

Combination of Candidate Microbicides Cellulose Acetate 1,2-Benzenedicarboxylate and UC781 Has Synergistic and Complementary Effects against Human Immunodeficiency Virus Type 1 Infection
Antimicrob. Agents Chemother. 2005 49: 1830-1836. [Abstract] [Full Text] [PDF]  

William A. Lee, Gong-Xin He, Eugene Eisenberg, Tomas Cihlar, Swami Swaminathan, Andrew Mulato, and Kenneth C. Cundy

Selective Intracellular Activation of a Novel Prodrug of the Human Immunodeficiency Virus Reverse Transcriptase Inhibitor Tenofovir Leads to Preferential Distribution and Accumulation in Lymphatic Tissue
Antimicrob. Agents Chemother. 2005 49: 1898-1906. [Abstract] [Full Text] [PDF]  

Alain Pruvost, Eugènia Negredo, Henri Benech, Frédéric Theodoro, Jordi Puig, Eulàlia Grau, Elisabet García, José Moltó, Jacques Grassi, and Bonaventura Clotet

Measurement of Intracellular Didanosine and Tenofovir Phosphorylated Metabolites and Possible Interaction of the Two Drugs in Human Immunodeficiency Virus-Infected Patients
Antimicrob. Agents Chemother. 2005 49: 1907-1914. [Abstract] [Full Text] [PDF]  

Adrian S. Ray, Brenda I. Hernandez-Santiago, Judy S. Mathew, Eisuke Murakami, Carey Bozeman, Meng-Yu Xie, Ginger E. Dutschman, Elizabeth Gullen, Zhenjun Yang, Selwyn Hurwitz, Yung-Chi Cheng, Chung K. Chu, Harold McClure, Raymond F. Schinazi, and Karen S. Anderson

Mechanism of Anti-Human Immunodeficiency Virus Activity of ß-D-6-Cyclopropylamino-2',3'-Didehydro-2',3'-Dideoxyguanosine
Antimicrob. Agents Chemother. 2005 49: 1994-2001. [Abstract] [Full Text] [PDF]  

Valentina Svicher, Francesca Ceccherini-Silberstein, Fulvio Erba, Maria Santoro, Caterina Gori, Maria Concetta Bellocchi, Sara Giannella, Maria Paola Trotta, Antonella d'Arminio Monforte, Andrea Antinori, and Carlo Federico Perno

Novel Human Immunodeficiency Virus Type 1 Protease Mutations Potentially Involved in Resistance to Protease Inhibitors
Antimicrob. Agents Chemother. 2005 49: 2015-2025. [Abstract] [Full Text] [PDF]  

Brandon Ason, Daniel J. Knauss, Allison M. Balke, George Merkel, Anna Marie Skalka, and William S. Reznikoff

Targeting Tn5 Transposase Identifies Human Immunodeficiency Virus Type 1 Inhibitors
Antimicrob. Agents Chemother. 2005 49: 2035-2043. [Abstract] [Full Text] [PDF]  

Rong Hu, Ling Li, Bart Degrève, Ginger E. Dutschman, Wing Lam, and Yung-Chi Cheng

Behavior of Thymidylate Kinase toward Monophosphate Metabolites and Its Role in the Metabolism of 1-(2'-Deoxy-2'-Fluoro-ß-L-Arabinofuranosyl)-5-Methyluracil (Clevudine) and 2',3'-Didehydro-2',3'-Dideoxythymidine in Cells
Antimicrob. Agents Chemother. 2005 49: 2044-2049. [Abstract] [Full Text] [PDF]  

Joanne E. Tomassini, Krista Getty, Mark W. Stahlhut, Sung Shim, Balkrishen Bhat, Anne B. Eldrup, Thazha P. Prakash, Steven S. Carroll, Osvaldo Flores, Malcolm MacCoss, Daniel R. McMasters, Giovanni Migliaccio, and David B. Olsen

Inhibitory Effect of 2'-Substituted Nucleosides on Hepatitis C Virus Replication Correlates with Metabolic Properties in Replicon Cells
Antimicrob. Agents Chemother. 2005 49: 2050-2058. [Abstract] [Full Text] [PDF]  

Steven W. Ludmerer, Donald J. Graham, Evelyn Boots, Edward M. Murray, Amy Simcoe, Eric J. Markel, Jay A. Grobler, Osvaldo A. Flores, David B. Olsen, Daria J. Hazuda, and Robert L. LaFemina

Replication Fitness and NS5B Drug Sensitivity of Diverse Hepatitis C Virus Isolates Characterized by Using a Transient Replication Assay
Antimicrob. Agents Chemother. 2005 49: 2059-2069. [Abstract] [Full Text] [PDF] [Supplemental material]  

Koen K. A. Van Rompay, Marta Hamilton, Brian Kearney, and Norbert Bischofberger

Pharmacokinetics of Tenofovir in Breast Milk of Lactating Rhesus Macaques
Antimicrob. Agents Chemother. 2005 49: 2093-2094. [Abstract] [Full Text] [PDF]  

Mechanisms of Action:

Dawn M. E. Bowdish, Donald J. Davidson, Monisha G. Scott, and Robert E. W. Hancock

Immunomodulatory Activities of Small Host Defense Peptides
Antimicrob. Agents Chemother. 2005 49: 1727-1732. [Abstract] [Full Text] [PDF]  

Yoshihiro Inoue, Toshiko Hada, Akiko Shiraishi, Kazuma Hirose, Hajime Hamashima, and Shigeki Kobayashi

Biphasic Effects of Geranylgeraniol, Teprenone, and Phytol on the Growth of Staphylococcus aureus
Antimicrob. Agents Chemother. 2005 49: 1770-1774. [Abstract] [Full Text] [PDF]  

Sabrina Sonda, Giusy Sala, Riccardo Ghidoni, Andrew Hemphill, and Jean Pieters

Inhibitory Effect of Aureobasidin A on Toxoplasma gondii
Antimicrob. Agents Chemother. 2005 49: 1794-1801. [Abstract] [Full Text] [PDF]  

Ryan A. Helmick, Arin E. Fletcher, Anne M. Gardner, Christopher R. Gessner, Angela N. Hvitved, Michael C. Gustin, and Paul R. Gardner

Imidazole Antibiotics Inhibit the Nitric Oxide Dioxygenase Function of Microbial Flavohemoglobin
Antimicrob. Agents Chemother. 2005 49: 1837-1843. [Abstract] [Full Text] [PDF]  

Linus L. Shen, Candace Black-Schaefer, Yingna Cai, Peter J. Dandliker, and Bruce A. Beutel

Mechanism of Action of a Novel Series of Naphthyridine-Type Ribosome Inhibitors: Enhancement of tRNA Footprinting at the Decoding Site of 16S rRNA
Antimicrob. Agents Chemother. 2005 49: 1890-1897. [Abstract] [Full Text] [PDF]  

Janine T. Lin, Mariah Bindel Connelly, Chris Amolo, Suzie Otani, and Debbie S. Yaver

Global Transcriptional Response of Bacillus subtilis to Treatment with Subinhibitory Concentrations of Antibiotics That Inhibit Protein Synthesis
Antimicrob. Agents Chemother. 2005 49: 1915-1926. [Abstract] [Full Text] [PDF]  

Jacob Strahilevitz and David C. Hooper

Dual Targeting of Topoisomerase IV and Gyrase To Reduce Mutant Selection: Direct Testing of the Paradigm by Using WCK-1734, a New Fluoroquinolone, and Ciprofloxacin
Antimicrob. Agents Chemother. 2005 49: 1949-1956. [Abstract] [Full Text] [PDF]  

Muhammad Malik, Tao Lu, Xilin Zhao, Anubha Singh, Christopher M. Hattan, John Domagala, Robert Kerns, and Karl Drlica

Lethality of Quinolones against Mycobacterium smegmatis in the Presence or Absence of Chloramphenicol
Antimicrob. Agents Chemother. 2005 49: 2008-2014. [Abstract] [Full Text] [PDF]  

S. A. G. Lambrechts, M. C. G. Aalders, and J. Van Marle

Mechanistic Study of the Photodynamic Inactivation of Candida albicans by a Cationic Porphyrin
Antimicrob. Agents Chemother. 2005 49: 2026-2034. [Abstract] [Full Text] [PDF]  

Susceptibility:

Nathalie Reveneau, Deborah D. Crane, Elizabeth Fischer, and Harlan D. Caldwell

Bactericidal Activity of First-Choice Antibiotics against Gamma Interferon-Induced Persistent Infection of Human Epithelial Cells by Chlamydia trachomatis
Antimicrob. Agents Chemother. 2005 49: 1787-1793. [Abstract] [Full Text] [PDF]  

Katrin Siewert, Jan Rupp, Matthias Klinger, Werner Solbach, and Jens Gieffers

Growth Cycle-Dependent Pharmacodynamics of Antichlamydial Drugs
Antimicrob. Agents Chemother. 2005 49: 1852-1856. [Abstract] [Full Text] [PDF]  

Klaudia Kosowska, Dianne B. Hoellman, Gengrong Lin, Catherine Clark, Kim Credito, Pamela McGhee, Bonifacio Dewasse, Bülent Bozdogan, Stuart Shapiro, and Peter C. Appelbaum

Antipneumococcal Activity of Ceftobiprole, a Novel Broad-Spectrum Cephalosporin
Antimicrob. Agents Chemother. 2005 49: 1932-1942. [Abstract] [Full Text] [PDF]  

Emilio Pérez-Trallero, Celia García-de-la-Fuente, César García-Rey, Fernando Baquero, Lorenzo Aguilar, Rafael Dal-Ré, Juan García-de-Lomas the Spanish Surveillance Group for Respiratory Pathogens

Geographical and Ecological Analysis of Resistance, Coresistance, and Coupled Resistance to Antimicrobials in Respiratory Pathogenic Bacteria in Spain
Antimicrob. Agents Chemother. 2005 49: 1965-1972. [Abstract] [Full Text] [PDF]  

Belkys Fernández-Torres, Isabel Inza, and Josep Guarro

Evaluation of Disk Diffusion Method for Determining Eberconazole Susceptibility of Dermatophytes and Influence of Culture Medium
Antimicrob. Agents Chemother. 2005 49: 2116-2118. [Abstract] [Full Text] [PDF]  

Mitchell J. Schwaber, Shiri Navon-Venezia, David Schwartz, and Yehuda Carmeli

High Levels of Antimicrobial Coresistance among Extended-Spectrum-ß-Lactamase-Producing Enterobacteriaceae
Antimicrob. Agents Chemother. 2005 49: 2137-2139. [Abstract] [Full Text] [PDF]  

Letters:

Sandra Quinteira, Helena Ferreira, and Luísa Peixe

First Isolation of bla_VIM-2 in an Environmental Isolate of Pseudomonas pseudoalcaligenes
Antimicrob. Agents Chemother. 2005 49: 2140-2141. [Full Text] [PDF]  

Emilio Valverde Romero, Trinidad Parras Padilla, M. Inmaculada García García, Nuria Delgado Ronda, Ana Herrero, Juan Luis Muñoz Bellido, and José Ángel García Rodríguez

Salmonella enterica Serovar Infantis Producing a CTX-M-9 ß-Lactamase
Antimicrob. Agents Chemother. 2005 49: 2142-2143. [Full Text] [PDF]  

Tomoo Saga, Mitsuo Kaku, Yoshikuni Onodera, Shinichiro Yamachika, Kenichi Sato, and Hiroyuki Takase

Vibrio parahaemolyticus Chromosomal qnr Homologue VPA0095: Demonstration by Transformation with a Mutated Gene of Its Potential To Reduce Quinolone Susceptibility in Escherichia coli
Antimicrob. Agents Chemother. 2005 49: 2144-2145. [Full Text] [PDF]  

Hasan Nazic, Laurent Poirel, and Patrice Nordmann

Further Identification of Plasmid-Mediated Quinolone Resistance Determinant in Enterobacteriaceae in Turkey
Antimicrob. Agents Chemother. 2005 49: 2146-2147. [Full Text] [PDF]  

Sang Hee Lee, Seok Hoon Jeong, Jun-ichi Wachino, Yoshichika Arakawa, L. Poirel, and P. Nordmann

Nomenclature of GES-Type Extended-Spectrum ß-Lactamases
Antimicrob. Agents Chemother. 2005 49: 2148-2150. [Full Text] [PDF]  

Recent Approvals:

New Antimicrobial Agents Approved by the U.S. Food and Drug Administration in 2004 and New Indications for Previously Approved Agents
Antimicrob. Agents Chemother. 2005 49: 2151. [Full Text] [PDF]  

Errata:

Emergence of Daptomycin Resistance in Enterococcus faecium during Daptomycin Therapy
Antimicrob. Agents Chemother. 2005 49: 2152. [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.