Contents: June 2005, Volume 49, Issue 6        Minireviews        Antiviral Agents        Mechanisms of Action        Clinical Therapeutics        Mechanisms of Resistance        Experimental Therapeutics        Susceptibility        Pharmacology        Analytical Procedures        Letters Other Issues

Table of Contents

[Index by Author]

To see an article, click its [Full Text], [Abstract] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

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Minireviews:

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New Small-Molecule Synthetic Antimycobacterials Lluis Ballell, Robert A. Field, Ken Duncan, and Robert J. Young Antimicrob. Agents Chemother. June 2005 49: 2153-2163; [Full Text] [PDF] [Reprints and Permissions]

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Antiviral Agents:

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Phosphorylation of Ribavirin and Viramidine by Adenosine Kinase and Cytosolic 5'-Nucleotidase II: Implications for Ribavirin Metabolism in Erythrocytes Jim Zhen Wu, Gary Larson, Heli Walker, Jae Hoon Shim, and Zhi Hong Antimicrob. Agents Chemother. June 2005 49: 2164-2171; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Antiviral Activity and Single-Dose Pharmacokinetics in Humans of a Novel, Orally Bioavailable Inhibitor of Human Rhinovirus 3C Protease Amy K. Patick, Mary A. Brothers, Fausto Maldonado, Susan Binford, Oscar Maldonado, Shella Fuhrman, Annkatrin Petersen, George J. Smith, III, Leora S. Zalman, Leigh Ann Burns-Naas, and Jonathan Q. Tran Antimicrob. Agents Chemother. June 2005 49: 2267-2275; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

TMC114, a Novel Human Immunodeficiency Virus Type 1 Protease Inhibitor Active against Protease Inhibitor-Resistant Viruses, Including a Broad Range of Clinical Isolates Sandra De Meyer, Hilde Azijn, Dominique Surleraux, Dirk Jochmans, Abdellah Tahri, Rudi Pauwels, Piet Wigerinck, and Marie-Pierre de Béthune Antimicrob. Agents Chemother. June 2005 49: 2314-2321; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Interferon Alfacon-1 Protects Hamsters from Lethal Pichinde Virus Infection Brian B. Gowen, Dale L. Barnard, Donald F. Smee, Min-Hui Wong, Anne M. Pace, Kie-Hoon Jung, Scott G. Winslow, Kevin W. Bailey, Lawrence M. Blatt, and Robert W. Sidwell Antimicrob. Agents Chemother. June 2005 49: 2378-2386; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Small Molecules VP-14637 and JNJ-2408068 Inhibit Respiratory Syncytial Virus Fusion by Similar Mechanisms Janet L. Douglas, Marites L. Panis, Edmund Ho, Kuei-Ying Lin, Steve H. Krawczyk, Deborah M. Grant, Ruby Cai, Swami Swaminathan, Xiaowu Chen, and Tomas Cihlar Antimicrob. Agents Chemother. June 2005 49: 2460-2466; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Mechanisms of Action:

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IMP Dehydrogenase from the Protozoan Parasite Toxoplasma gondii William J. Sullivan, Jr., Stacy E. Dixon, Catherine Li, Boris Striepen, and Sherry F. Queener Antimicrob. Agents Chemother. June 2005 49: 2172-2179; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Are Transporter Genes Other than the Chloroquine Resistance Locus (pfcrt) and Multidrug Resistance Gene (pfmdr) Associated with Antimalarial Drug Resistance? Timothy J. C. Anderson, Shalini Nair, Huang Qin, Sittaporn Singlam, Alan Brockman, Lucy Paiphun, and François Nosten Antimicrob. Agents Chemother. June 2005 49: 2180-2188; [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]

Genome-Wide Expression Profiling of the Response to Azole, Polyene, Echinocandin, and Pyrimidine Antifungal Agents in Candida albicans Teresa T. Liu, Robin E. B. Lee, Katherine S. Barker, Richard E. Lee, Lai Wei, Ramin Homayouni, and P. David Rogers Antimicrob. Agents Chemother. June 2005 49: 2226-2236; [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]

Transcriptional Response of Enterococcus faecalis V583 to Erythromycin Ågot Aakra, Heidi Vebø, Lars Snipen, Helmut Hirt, Are Aastveit, Vivek Kapur, Gary Dunny, Barbara Murray, and Ingolf F. Nes Antimicrob. Agents Chemother. June 2005 49: 2246-2259; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Combination of Antimicrobial and Endotoxin-Neutralizing Activities of Novel Oleoylamines Mateja Zorko, Andreja Majerle, David Sarlah, Mateja Mancek Keber, Barbara Mohar, and Roman Jerala Antimicrob. Agents Chemother. June 2005 49: 2307-2313; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Divalent Metal Cations Increase the Activity of the Antimicrobial Peptide Kappacin Stuart G. Dashper, Neil M. O'Brien-Simpson, Keith J. Cross, Rita A. Paolini, Brigitte Hoffmann, Deanne V. Catmull, Marina Malkoski, and Eric C. Reynolds Antimicrob. Agents Chemother. June 2005 49: 2322-2328; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Effect of Cell-Photosensitizer Binding and Cell Density on Microbial Photoinactivation Tatiana N. Demidova and Michael R. Hamblin Antimicrob. Agents Chemother. June 2005 49: 2329-2335; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Human Salivary Mucin MUC7 12-Mer-L and 12-Mer-D Peptides: Antifungal Activity in Saliva, Enhancement of Activity with Protease Inhibitor Cocktail or EDTA, and Cytotoxicity to Human Cells Guo-Xian Wei and Libuse A. Bobek Antimicrob. Agents Chemother. June 2005 49: 2336-2342; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Cellular Uptake and Efflux of Azithromycin, Erythromycin, Clarithromycin, Telithromycin, and Cethromycin Martina Bosnar, Zeljko Kelneric, Vesna Munic, Vesna Erakovic, and Michael J. Parnham Antimicrob. Agents Chemother. June 2005 49: 2372-2377; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Proline Conformation-Dependent Antimicrobial Activity of a Proline-Rich Histone H1 N-Terminal Peptide Fragment Isolated from the Skin Mucus of Atlantic Salmon Torben Lüders, Gunn Alice Birkemo, Jon Nissen-Meyer, Øivind Andersen, and Ingolf F. Nes Antimicrob. Agents Chemother. June 2005 49: 2399-2406; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Effects of Acyl versus Aminoacyl Conjugation on the Properties of Antimicrobial Peptides Inna S. Radzishevsky, Shahar Rotem, Fadia Zaknoon, Leonid Gaidukov, Arie Dagan, and Amram Mor Antimicrob. Agents Chemother. June 2005 49: 2412-2420; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antifungal Protein PAF Severely Affects the Integrity of the Plasma Membrane of Aspergillus nidulans and Induces an Apoptosis-Like Phenotype Éva Leiter, Henrietta Szappanos, Christoph Oberparleiter, Lydia Kaiserer, László Csernoch, Tünde Pusztahelyi, Tamás Emri, István Pócsi, Willibald Salvenmoser, and Florentine Marx Antimicrob. Agents Chemother. June 2005 49: 2445-2453; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mechanisms of Antibacterial Action of Three Monoterpenes Domenico Trombetta, Francesco Castelli, Maria Grazia Sarpietro, Vincenza Venuti, Mariateresa Cristani, Claudia Daniele, Antonella Saija, Gabriela Mazzanti, and Giuseppe Bisignano Antimicrob. Agents Chemother. June 2005 49: 2474-2478; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Utilization of Target-Specific, Hypersensitive Strains of Saccharomyces cerevisiae To Determine the Mode of Action of Antifungal Compounds Ed T. Buurman, Beth Andrews, April E. Blodgett, Jini S. Chavda, and Norbert F. Schnell Antimicrob. Agents Chemother. June 2005 49: 2558-2560; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Clinical Therapeutics:

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Pharmacodynamic Modeling of the Evolution of Levofloxacin Resistance in Staphylococcus aureus Jeffrey J. Campion, Philip Chung, Patrick J. McNamara, William B. Titlow, and Martin E. Evans Antimicrob. Agents Chemother. June 2005 49: 2189-2199; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Linezolid versus Vancomycin in Treatment of Complicated Skin and Soft Tissue Infections John Weigelt, Kamal Itani, Dennis Stevens, William Lau, Matthew Dryden, Charles Knirsch the Linezolid CSSTI Study Group Antimicrob. Agents Chemother. June 2005 49: 2260-2266; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Mechanisms of Resistance:

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Detection of rpoB Mutations Associated with Rifampin Resistance in Mycobacterium tuberculosis Using Denaturing Gradient Gel Electrophoresis Mark T. McCammon, John S. Gillette, Derek P. Thomas, Srinivas V. Ramaswamy, Edward A. Graviss, Barry N. Kreiswirth, Jan Vijg, and Teresa N. Quitugua Antimicrob. Agents Chemother. June 2005 49: 2200-2209; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Detection by Denaturing Gradient Gel Electrophoresis of pncA Mutations Associated with Pyrazinamide Resistance in Mycobacterium tuberculosis Isolates from the United States-Mexico Border Region Mark T. McCammon, John S. Gillette, Derek P. Thomas, Srinivas V. Ramaswamy, Ishmael I. Rosas, Edward A. Graviss, Jan Vijg, and Teresa N. Quitugua Antimicrob. Agents Chemother. June 2005 49: 2210-2217; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Phenotypic and Molecular Characterization of Mycobacterium tuberculosis Isolates Resistant to both Isoniazid and Ethambutol Linda M. Parsons, Max Salfinger, Anne Clobridge, Jillian Dormandy, Lisa Mirabello, Valerie L. Polletta, Ahmet Sanic, Oleg Sinyavskiy, Susan C. Larsen, Jeffrey Driscoll, Genet Zickas, and Harry W. Taber Antimicrob. Agents Chemother. June 2005 49: 2218-2225; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

New Mutations and Horizontal Transfer of rpoB among Rifampin-Resistant Streptococcus pneumoniae from Four Spanish Hospitals María José Ferrándiz, Carmen Ardanuy, Josefina Liñares, José María García-Arenzana, Emilia Cercenado, Ana Fleites, Adela G. de la Campa the Spanish Pneumococcal Infection Study Network Antimicrob. Agents Chemother. June 2005 49: 2237-2245; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Occurrence of Hypermutable Pseudomonas aeruginosa in Cystic Fibrosis Patients Is Associated with the Oxidative Stress Caused by Chronic Lung Inflammation Oana Ciofu, Bente Riis, Tacjana Pressler, Henrik Enghusen Poulsen, and Niels Høiby Antimicrob. Agents Chemother. June 2005 49: 2276-2282; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Inducible Clindamycin Resistance and Molecular Epidemiologic Trends of Pediatric Community-Acquired Methicillin-Resistant Staphylococcus aureus in Dallas, Texas Susana Chavez-Bueno, Bülent Bozdogan, Kathy Katz, Karen L. Bowlware, Nancy Cushion, Dominick Cavuoti, Naveed Ahmad, George H. McCracken, Jr., and Peter C. Appelbaum Antimicrob. Agents Chemother. June 2005 49: 2283-2288; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Emergence of Macrolide-Resistant Mycoplasma pneumoniae with a 23S rRNA Gene Mutation Miyuki Morozumi, Keiko Hasegawa, Reiko Kobayashi, Nagako Inoue, Satoshi Iwata, Haruo Kuroki, Naohisa Kawamura, Eiichi Nakayama, Takeshi Tajima, Kouichi Shimizu, and Kimiko Ubukata Antimicrob. Agents Chemother. June 2005 49: 2302-2306; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Biological Cost of Single and Multiple Norfloxacin Resistance Mutations in Escherichia coli Implicated in Urinary Tract Infections Patricia Komp Lindgren, Linda L. Marcusson, Dorthe Sandvang, Niels Frimodt-Møller, and Diarmaid Hughes Antimicrob. Agents Chemother. June 2005 49: 2343-2351; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mosaic Structure of a Multiple-Drug-Resistant, Conjugative Plasmid from Campylobacter jejuni Warawadee Nirdnoy, Carl J. Mason, and Patricia Guerry Antimicrob. Agents Chemother. June 2005 49: 2454-2459; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Novel Ser79Leu and Ser81Ile Substitutions in the Quinolone Resistance-Determining Regions of ParC Topoisomerase IV and GyrA DNA Gyrase Subunits from Recent Fluoroquinolone-Resistant Streptococcus pneumoniae Clinical Isolates Nataliya Korzheva, Todd A. Davies, and Raul Goldschmidt Antimicrob. Agents Chemother. June 2005 49: 2479-2486; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

DNA in Antibiotic Preparations: Absence of Intact Resistance Genes Markus Woegerbauer, Heimo Lagler, Wolfgang Graninger, and Heinz Burgmann Antimicrob. Agents Chemother. June 2005 49: 2490-2494; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Fluoroquinolone-Resistant Streptococcus agalactiae: Epidemiology and Mechanism of Resistance Wehbeh Wehbeh, Roberto Rojas-Diaz, Xinying Li, Noriel Mariano, Louise Grenner, Sorana Segal-Maurer, Barbara Tommasulo, Karl Drlica, Carl Urban, and James J. Rahal Antimicrob. Agents Chemother. June 2005 49: 2495-2497; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Class I Integron with a Group II Intron Detected in an Escherichia coli Strain from a Free-Range Reindeer Marianne Sunde Antimicrob. Agents Chemother. June 2005 49: 2512-2514; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Isolation and Expression of a Novel Molecular Class D ß-Lactamase, OXA-61, from Campylobacter jejuni David A. Alfredson and Victoria Korolik Antimicrob. Agents Chemother. June 2005 49: 2515-2518; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Detection of qnr in Clinical Isolates of Escherichia coli from Korea Jin-Yong Jeong, Hyun Jung Yoon, Eun Sil Kim, Yoola Lee, Sang-Ho Choi, Nam Joong Kim, Jun Hee Woo, and Yang Soo Kim Antimicrob. Agents Chemother. June 2005 49: 2522-2524; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Multicenter Study of the Mechanisms of Resistance and Clonal Relationships of Streptococcus agalactiae Isolates Resistant to Macrolides, Lincosamides, and Ketolides in Spain J. J. Gonzalez, A. Andreu the Spanish Group for the Study of Perinatal Infection from the Spanish Society for Clinical Microbiology and Infectious Diseases Antimicrob. Agents Chemother. June 2005 49: 2525-2527; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Targeted Gene Disruption of the 14- Sterol Demethylase (cyp51A) in Aspergillus fumigatus and Its Role in Azole Drug Susceptibility E. Mellado, G. Garcia-Effron, M. J. Buitrago, L. Alcazar-Fuoli, M. Cuenca-Estrella, and J. L. Rodriguez-Tudela Antimicrob. Agents Chemother. June 2005 49: 2536-2538; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

ErmB Determinants and Tn916-Like Elements in Clinical Isolates of Clostridium difficile Patrizia Spigaglia, Valentina Carucci, Fabrizio Barbanti, and Paola Mastrantonio Antimicrob. Agents Chemother. June 2005 49: 2550-2553; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Chromosome-Borne Class A BOR-1 ß-Lactamase of Bordetella bronchiseptica and Bordetella parapertussis Marie-Frédérique Lartigue, Laurent Poirel, Nicolas Fortineau, and Patrice Nordmann Antimicrob. Agents Chemother. June 2005 49: 2565-2567; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Identification of CTX-M-14 ß-Lactamase in a Salmonella enterica Serovar Enteritidis Isolate from Japan Hidemasa Izumiya, Kadumi Mori, Masato Higashide, Kazumichi Tamura, Nobuko Takai, Kenji Hirose, Jun Terajima, and Haruo Watanabe Antimicrob. Agents Chemother. June 2005 49: 2568-2570; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Experimental Therapeutics:

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Bactericidal Activity of the Nitroimidazopyran PA-824 in a Murine Model of Tuberculosis Sandeep Tyagi, E. Nuermberger, T. Yoshimatsu, K. Williams, I. Rosenthal, N. Lounis, W. Bishai, and J. Grosset Antimicrob. Agents Chemother. June 2005 49: 2289-2293; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Preclinical Testing of the Nitroimidazopyran PA-824 for Activity against Mycobacterium tuberculosis in a Series of In Vitro and In Vivo Models Anne J. Lenaerts, Veronica Gruppo, Karen S. Marietta, Christine M. Johnson, Diane K. Driscoll, Nicholas M. Tompkins, Jerry D. Rose, Robert C. Reynolds, and Ian M. Orme Antimicrob. Agents Chemother. June 2005 49: 2294-2301; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Intravesical Nitric Oxide Delivery for Prevention of Catheter-Associated Urinary Tract Infections Stefan Carlsson, Eddie Weitzberg, Peter Wiklund, and Jon O. Lundberg Antimicrob. Agents Chemother. June 2005 49: 2352-2355; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Microdialysis Study of Imipenem Distribution in Skeletal Muscle and Lung Extracellular Fluids of Noninfected Rats Sandrine Marchand, Claire Dahyot, Isabelle Lamarche, Olivier Mimoz, and William Couet Antimicrob. Agents Chemother. June 2005 49: 2356-2361; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Comparable Efficacies of the Antimicrobial Peptide Human Lactoferrin 1-11 and Gentamicin in a Chronic Methicillin-Resistant Staphylococcus aureus Osteomyelitis Model Christopher Faber, Hein P. Stallmann, D. M. Lyaruu, Uwe Joosten, Christof von Eiff, Arie van Nieuw Amerongen, and Paul I. J. M. Wuisman Antimicrob. Agents Chemother. June 2005 49: 2438-2444; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Caspofungin in Combination with Amphotericin B against Candida glabrata Francesco Barchiesi, Elisabetta Spreghini, Annette W. Fothergill, Daniela Arzeni, Gianfranco Greganti, Daniele Giannini, Michael G. Rinaldi, and Giorgio Scalise Antimicrob. Agents Chemother. June 2005 49: 2546-2549; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Susceptibility:

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Inhibitory Activity of Human Immunodeficiency Virus Aspartyl Protease Inhibitors against Encephalitozoon intestinalis Evaluated by Cell Culture-Quantitative PCR Assay Jean Menotti, Maud Santillana-Hayat, Bruno Cassinat, Claudine Sarfati, Francis Derouin, and Jean-Michel Molina Antimicrob. Agents Chemother. June 2005 49: 2362-2366; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antimycobacterial Agents Differ with Respect to Their Bacteriostatic versus Bactericidal Activities in Relation to Time of Exposure, Mycobacterial Growth Phase, and Their Use in Combination Irma A. J. M. Bakker-Woudenberg, Wim van Vianen, Dick van Soolingen, Henri A. Verbrugh, and Michiel A. van Agtmael Antimicrob. Agents Chemother. June 2005 49: 2387-2398; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activity of Telithromycin against Macrolide-Susceptible and Macrolide-Resistant Pharyngeal Isolates of Group A Streptococci in the United States Michael Green, Coburn Allen, John Bradley, Barry Dashefsky, Janet R. Gilsdorf, Mario J. Marcon, Gordon E. Schutze, Clay Smith, Emmanuel Walter, Judith M. Martin, Kathryn A. Edwards, Karen A. Barbadora, Renee M. Rumbaugh, and Ellen R. Wald Antimicrob. Agents Chemother. June 2005 49: 2487-2489; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro and In Vivo Activities of DA-7867, a New Oxazolidinone, against Aerobic Gram-Positive Bacteria Eun Jeong Yoon, Yeong Woo Jo, Sung Hak Choi, Tae Ho Lee, Jae Keol Rhee, Moohi Yoo, Mi Ja Shim, and Eung Chil Choi Antimicrob. Agents Chemother. June 2005 49: 2498-2500; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Biosynthesized Tea Polyphenols Inactivate Chlamydia trachomatis In Vitro Tsutomu Yamazaki, Toshio Kishimoto, Sadashi Shiga, Kozue Sato, Toshikatsu Hagiwara, Miyuki Inoue, Nozomu Sasaki, Kazunobu Ouchi, and Yukihiko Hara Antimicrob. Agents Chemother. June 2005 49: 2501-2503; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activity and Killing Effect of Citropin 1.1 against Gram-Positive Pathogens Causing Skin and Soft Tissue Infections Andrea Giacometti, Oscar Cirioni, Wojciech Kamysz, Carmela Silvestri, Maria Simona Del Prete, Alberto Licci, Giuseppina D'Amato, Jerzy Lukasiak, and Giorgio Scalise Antimicrob. Agents Chemother. June 2005 49: 2507-2509; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activity of Doripenem (S-4661) against Multidrug-Resistant Gram-Negative Bacilli Isolated from Patients with Cystic Fibrosis Yunhua Chen, Elizabeth Garber, Qiuqu Zhao, Yigong Ge, Matthew A. Wikler, Koné Kaniga, and Lisa Saiman Antimicrob. Agents Chemother. June 2005 49: 2510-2511; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Inhibitory Effects of Hinokitiol on Proliferation of Chlamydia trachomatis Hiroaki Yamano, Tsutomu Yamazaki, Kozue Sato, Sadashi Shiga, Toshikatsu Hagiwara, Kazunobu Ouchi, and Toshio Kishimoto Antimicrob. Agents Chemother. June 2005 49: 2519-2521; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro and Intracellular Activities of LBM415 (NVP PDF-713) against Legionella pneumophila Paul H. Edelstein, Baofeng Hu, and Martha A. C. Edelstein Antimicrob. Agents Chemother. June 2005 49: 2533-2535; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activities of Amphotericin B and Voriconazole against Aleurioconidia from Aspergillus terreus Cornelia Lass-Flörl, Alexandra Rief, Sandra Leitner, Cornelia Speth, Reinhard Würzner, and Manfred P. Dierich Antimicrob. Agents Chemother. June 2005 49: 2539-2540; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Comparative In Vitro Activities of Investigational Peptide Deformylase Inhibitor NVP LBM-415 and Other Agents against Human Mycoplasmas and Ureaplasmas Ken B. Waites, Nipun B. Reddy, Donna M. Crabb, and Lynn B. Duffy Antimicrob. Agents Chemother. June 2005 49: 2541-2542; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Selection of Cross-Resistance following Exposure of Pseudomonas aeruginosa Clinical Isolates to Ciprofloxacin or Cefepime Samer A. Alyaseen, Kerryl E. Piper, Mark S. Rouse, James M. Steckelberg, and Robin Patel Antimicrob. Agents Chemother. June 2005 49: 2543-2545; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Decreasing Prevalence of ß-Lactamase Production among Respiratory Tract Isolates of Haemophilus influenzae in the United States Kris P. Heilmann, Cassie L. Rice, Ashley L. Miller, Norma J. Miller, Susan E. Beekmann, Michael A. Pfaller, Sandra S. Richter, and Gary V. Doern Antimicrob. Agents Chemother. June 2005 49: 2561-2564; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Posttreatment Changes in Escherichia coli Antimicrobial Susceptibility Rates among Diarrheic Patients Treated with Ciprofloxacin Shannon D. Putnam, John W. Sanders, David R. Tribble, David R. Rockabrand, Mark S. Riddle, Patrick J. Rozmajzl, and Robert W. Frenck Antimicrob. Agents Chemother. June 2005 49: 2571-2572; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Pharmacology:

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Penetration of Linezolid into Soft Tissues of Healthy Volunteers after Single and Multiple Doses Pejman Dehghanyar, Cornelia Bürger, Markus Zeitlinger, Florian Islinger, Florian Kovar, Markus Müller, Charlotte Kloft, and Christian Joukhadar Antimicrob. Agents Chemother. June 2005 49: 2367-2371; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Effects of a High-Fat Meal on the Relative Oral Bioavailability of Piperaquine Ing-Kye Sim, Timothy M. E. Davis, and Kenneth F. Ilett Antimicrob. Agents Chemother. June 2005 49: 2407-2411; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pharmacokinetics and Pharmacodynamics of Imipenem during Continuous Renal Replacement Therapy in Critically Ill Patients Douglas N. Fish, Isaac Teitelbaum, and Edward Abraham Antimicrob. Agents Chemother. June 2005 49: 2421-2428; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Influence of Efflux Transporters on the Accumulation and Efflux of Four Quinolones (Ciprofloxacin, Levofloxacin, Garenoxacin, and Moxifloxacin) in J774 Macrophages Jean-Michel Michot, Cristina Seral, Françoise Van Bambeke, Marie-Paule Mingeot-Leclercq, and Paul M. Tulkens Antimicrob. Agents Chemother. June 2005 49: 2429-2437; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Population Pharmacokinetics of Abacavir in Plasma and Cerebrospinal Fluid Edmund V. Capparelli, Scott L. Letendre, Ronald J. Ellis, Parul Patel, Diane Holland, and J. Allen McCutchan Antimicrob. Agents Chemother. June 2005 49: 2504-2506; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Effect of CYP3A1(23) Induction on Clarithromycin Pharmacokinetics in Rats with Diabetes Mellitus Yu C. Kim, Joo H. Lee, So H. Kim, and Myung G. Lee Antimicrob. Agents Chemother. June 2005 49: 2528-2532; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

Levofloxacin Disposition over Time in Aqueous Humor of Patients Undergoing Cataract Surgery Federico Pea, Ettore Ferrari, Federica Pavan, Derri Roman-Pognuz, Francesco Bandello, and Mario Furlanut Antimicrob. Agents Chemother. June 2005 49: 2554-2557; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Analytical Procedures:

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Use of Confocal Microscopy To Analyze the Rate of Vancomycin Penetration through Staphylococcus aureus Biofilms Kimberly K. Jefferson, Donald A. Goldmann, and Gerald B. Pier Antimicrob. Agents Chemother. June 2005 49: 2467-2473; [Abstract] [Full Text] [PDF] [Reprints and Permissions]

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Letters:

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The ORF1 Gene Located on the Class-1-Integron-Associated Gene Cassette Actually Represents a Novel Fosfomycin Resistance Determinant Jun Yatsuyanagi, Shioko Saito, Takayuki Konno, Seizaburo Harata, Noriyuki Suzuki, and Ken-ichi Amano Antimicrob. Agents Chemother. June 2005 49: 2573 [Full Text] [PDF] [Reprints and Permissions]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.