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Minireviews:

Joshua D. Nosanchuk and Arturo Casadevall

Impact of Melanin on Microbial Virulence and Clinical Resistance to Antimicrobial Compounds
Antimicrob. Agents Chemother. 2006 50: 3519-3528. [Full Text] [PDF] [Reprints and Permissions]  

Clinical Therapeutics:

C. Andrew DeRyke, Christina Sutherland, Bo Zhang, David P. Nicolau, and Joseph L. Kuti

Serum Bactericidal Activities of High-Dose Daptomycin with and without Coadministration of Gentamicin against Isolates of Staphylococcus aureus and Enterococcus species
Antimicrob. Agents Chemother. 2006 50: 3529-3534. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

William K. Lau, David Mercer, Kamal M. Itani, David P. Nicolau, Joseph L. Kuti, Debra Mansfield, and Adrian Dana

Randomized, Open-Label, Comparative Study of Piperacillin-Tazobactam Administered by Continuous Infusion versus Intermittent Infusion for Treatment of Hospitalized Patients with Complicated Intra-Abdominal Infection
Antimicrob. Agents Chemother. 2006 50: 3556-3561. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jean-Paul Guthmann, Loretxu Pinoges, Francesco Checchi, Simon Cousens, Suna Balkan, Michel van Herp, Dominique Legros, and Piero Olliaro

Methodological Issues in the Assessment of Antimalarial Drug Treatment: Analysis of 13 Studies in Eight African Countries from 2001 to 2004
Antimicrob. Agents Chemother. 2006 50: 3734-3739. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Yusuke Tanigawara, Reiko Sato, Kunihiko Morita, Mitsuo Kaku, Naoki Aikawa, and Kihachiro Shimizu

Population Pharmacokinetics of Arbekacin in Patients Infected with Methicillin-Resistant Staphylococcus aureus
Antimicrob. Agents Chemother. 2006 50: 3754-3762. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Reiko Sato, Yusuke Tanigawara, Mitsuo Kaku, Naoki Aikawa, and Kihachiro Shimizu

Pharmacokinetic-Pharmacodynamic Relationship of Arbekacin for Treatment of Patients Infected with Methicillin-Resistant Staphylococcus aureus
Antimicrob. Agents Chemother. 2006 50: 3763-3769. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Florian M. E. Wagenlehner, Martina Kinzig-Schippers, Uwe Tischmeyer, Christine Wagenlehner, Fritz Sörgel, and Kurt G. Naber

Urinary Bactericidal Activity of Extended-Release Ciprofloxacin (1,000 Milligrams) versus Levofloxacin (500 Milligrams) in Healthy Volunteers Receiving a Single Oral Dose
Antimicrob. Agents Chemother. 2006 50: 3947-3949. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Experimental Therapeutics:

L. Mark Kao, Karen Bush, Roy Barnewall, James Estep, Frederic W. Thalacker, Pamela H. Olson, George L. Drusano, Neil Minton, Shuchean Chien, Alex Hemeryck, and Michael F. Kelley

Pharmacokinetic Considerations and Efficacy of Levofloxacin in an Inhalational Anthrax (Postexposure) Rhesus Monkey Model
Antimicrob. Agents Chemother. 2006 50: 3535-3542. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Nacer Lounis, Nicolas Veziris, Aurélie Chauffour, Chantal Truffot-Pernot, Koen Andries, and Vincent Jarlier

Combinations of R207910 with Drugs Used To Treat Multidrug-Resistant Tuberculosis Have the Potential To Shorten Treatment Duration
Antimicrob. Agents Chemother. 2006 50: 3543-3547. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

David M. Rothstein, Ronald S. Farquhar, Klari Sirokman, Karen L. Sondergaard, Charles Hazlett, Angelia A. Doye, Judith K. Gwathmey, Steve Mullin, John van Duzer, and Christopher K. Murphy

Efficacy of Novel Rifamycin Derivatives against Rifamycin-Sensitive and -Resistant Staphylococcus aureus Isolates in Murine Models of Infection
Antimicrob. Agents Chemother. 2006 50: 3658-3664. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

William W. Hope, Peter A. Warn, Andrew Sharp, Susan Howard, Miki Kasai, Arnold Louie, Thomas J. Walsh, George L. Drusano, and David W. Denning

Derivation of an In Vivo Drug Exposure Breakpoint for Flucytosine against Candida albicans and Impact of the MIC, Growth Rate, and Resistance Genotype on the Antifungal Effect
Antimicrob. Agents Chemother. 2006 50: 3680-3688. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Tawanda Gumbo, George L. Drusano, Weiguo Liu, Lei Ma, Mark R. Deziel, Michael F. Drusano, and Arnold Louie

Anidulafungin Pharmacokinetics and Microbial Response in Neutropenic Mice with Disseminated Candidiasis
Antimicrob. Agents Chemother. 2006 50: 3695-3700. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Aneliya Milanova Haritova, Nikolina Velizarova Rusenova, Parvan Rusenov Parvanov, Lubomir Dimitrov Lashev, and Johanna Fink-Gremmels

Integration of Pharmacokinetic and Pharmacodynamic Indices of Marbofloxacin in Turkeys
Antimicrob. Agents Chemother. 2006 50: 3779-3785. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kathleen J. Zaleski, Tadeusz Kolodka, Colette Cywes-Bentley, Rachel M. McLoughlin, Mary L. Delaney, Bernard T. Charlton, Wendy Johnson, and Arthur O. Tzianabos

Hyaluronic Acid Binding Peptides Prevent Experimental Staphylococcal Wound Infection
Antimicrob. Agents Chemother. 2006 50: 3856-3860. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Stephen Rittenhouse, Christine Singley, Jennifer Hoover, Roni Page, and David Payne

Use of the Surgical Wound Infection Model To Determine the Efficacious Dosing Regimen of Retapamulin, a Novel Topical Antibiotic
Antimicrob. Agents Chemother. 2006 50: 3886-3888. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Usha Stiefel, Agam Rao, Michael J. Pultz, Robin L. P. Jump, David C. Aron, and Curtis J. Donskey

Suppression of Gastric Acid Production by Proton Pump Inhibitor Treatment Facilitates Colonization of the Large Intestine by Vancomycin-Resistant Enterococcus spp. and Klebsiella pneumoniae in Clindamycin-Treated Mice
Antimicrob. Agents Chemother. 2006 50: 3905-3907. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Chiatogu Onyewu, Natalie A. Afshari, and Joseph Heitman

Calcineurin Promotes Infection of the Cornea by Candida albicans and Can Be Targeted To Enhance Fluconazole Therapy
Antimicrob. Agents Chemother. 2006 50: 3963-3965. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pharmacology:

Vincent Jullien, Saïk Urien, Déborah Hirt, Constance Delaugerre, Elisabeth Rey, Jean-Paul Teglas, Paula Vaz, Christine Rouzioux, Marie-Laure Chaix, Eugenia Macassa, Ghislaine Firtion, Gérard Pons, Stéphane Blanche, and Jean-Marc Tréluyer

Population Analysis of Weight-, Age-, and Sex-Related Differences in the Pharmacokinetics of Lopinavir in Children from Birth to 18 Years
Antimicrob. Agents Chemother. 2006 50: 3548-3555. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

S. A. Van Wart, J. S. Owen, E. A. Ludwig, A. K. Meagher, J. M. Korth-Bradley, and B. B. Cirincione

Population Pharmacokinetics of Tigecycline in Patients with Complicated Intra-Abdominal or Skin and Skin Structure Infections
Antimicrob. Agents Chemother. 2006 50: 3701-3707. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sara Colombo, Thierry Buclin, Matthias Cavassini, Laurent A. Décosterd, Amalio Telenti, Jérôme Biollaz, and Chantal Csajka

Population Pharmacokinetics of Atazanavir in Patients with Human Immunodeficiency Virus Infection
Antimicrob. Agents Chemother. 2006 50: 3801-3808. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jason Cota, Michael Carden, John R. Graybill, Laura K. Najvar, David S. Burgess, and Nathan P. Wiederhold

In Vitro Pharmacodynamics of Anidulafungin and Caspofungin against Candida glabrata Isolates, Including Strains with Decreased Caspofungin Susceptibility
Antimicrob. Agents Chemother. 2006 50: 3926-3928. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Vincent H. Tam, Samer Kabbara, Rosa F. Yeh, and Robert H. Leary

Impact of Sample Size on the Performance of Multiple-Model Pharmacokinetic Simulations
Antimicrob. Agents Chemother. 2006 50: 3950-3952. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Resistance:

Maria J. Gomez and Alexander A. Neyfakh

Genes Involved in Intrinsic Antibiotic Resistance of Acinetobacter baylyi
Antimicrob. Agents Chemother. 2006 50: 3562-3567. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Stephen J. Billington and B. Helen Jost

Multiple Genetic Elements Carry the Tetracycline Resistance Gene tet(W) in the Animal Pathogen Arcanobacterium pyogenes
Antimicrob. Agents Chemother. 2006 50: 3580-3587. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Anil K. Mangalappalli-Illathu and Darren R. Korber

Adaptive Resistance and Differential Protein Expression of Salmonella enterica Serovar Enteritidis Biofilms Exposed to Benzalkonium Chloride
Antimicrob. Agents Chemother. 2006 50: 3588-3596. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Elisabeth Aslangul, Laurent Massias, Alain Meulemans, Françoise Chau, Antoine Andremont, Patrice Courvalin, Bruno Fantin, and Raymond Ruimy

Acquired Gentamicin Resistance by Permeability Impairment in Enterococcus faecalis
Antimicrob. Agents Chemother. 2006 50: 3615-3621. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sho Takahata, Nami Senju, Yumi Osaki, Takuji Yoshida, and Takashi Ida

Amino Acid Substitutions in Mosaic Penicillin-Binding Protein 2 Associated with Reduced Susceptibility to Cefixime in Clinical Isolates of Neisseria gonorrhoeae
Antimicrob. Agents Chemother. 2006 50: 3638-3645. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

T. A. Figueiredo, S. I. Aguiar, J. Melo-Cristino, and M. Ramirez

DNA Methylase Activity as a Marker for the Presence of a Family of Phage-Like Elements Conferring Efflux-Mediated Macrolide Resistance in Streptococci
Antimicrob. Agents Chemother. 2006 50: 3689-3694. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Prasanna D. Khot, Peter A. Suci, R. Lance Miller, Raoul D. Nelson, and Bonnie J. Tyler

A Small Subpopulation of Blastospores in Candida albicans Biofilms Exhibit Resistance to Amphotericin B Associated with Differential Regulation of Ergosterol and ß-1,6-Glucan Pathway Genes
Antimicrob. Agents Chemother. 2006 50: 3708-3716. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Anil Kumar Singh, Rajen Haldar, Debabrata Mandal, and Manikuntala Kundu

Analysis of the Topology of Vibrio cholerae NorM and Identification of Amino Acid Residues Involved in Norfloxacin Resistance
Antimicrob. Agents Chemother. 2006 50: 3717-3723. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Rita Berisio, Natascia Corti, Peter Pfister, Ada Yonath, and Erik C. Böttger

23S rRNA 2058AG Alteration Mediates Ketolide Resistance in Combination with Deletion in L22
Antimicrob. Agents Chemother. 2006 50: 3816-3823. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Michael D. LaFleur, Carol A. Kumamoto, and Kim Lewis

Candida albicans Biofilms Produce Antifungal-Tolerant Persister Cells
Antimicrob. Agents Chemother. 2006 50: 3839-3846. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ying-Tsong Chen, Hung-Yu Shu, Ling-Hui Li, Tsai-Lien Liao, Keh-Ming Wu, Yih-Ru Shiau, Jing-Jou Yan, Ih-Jen Su, Shih-Feng Tsai, and Tsai-Ling Lauderdale

Complete Nucleotide Sequence of pK245, a 98-Kilobase Plasmid Conferring Quinolone Resistance and Extended-Spectrum-ß-Lactamase Activity in a Clinical Klebsiella pneumoniae Isolate
Antimicrob. Agents Chemother. 2006 50: 3861-3866. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Cédric Cagliero, Christian Mouline, Axel Cloeckaert, and Sophie Payot

Synergy between Efflux Pump CmeABC and Modifications in Ribosomal Proteins L4 and L22 in Conferring Macrolide Resistance in Campylobacter jejuni and Campylobacter coli
Antimicrob. Agents Chemother. 2006 50: 3893-3896. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Adnan Al-Lahham, Peter C. Appelbaum, Mark van der Linden, and Ralf René Reinert

Telithromycin-Nonsusceptible Clinical Isolates of Streptococcus pneumoniae from Europe
Antimicrob. Agents Chemother. 2006 50: 3897-3900. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Andrew S. Chau, Guodong Chen, Paul M. McNicholas, and Paul A. Mann

Molecular Basis for Enhanced Activity of Posaconazole against Absidia corymbifera and Rhizopus oryzae
Antimicrob. Agents Chemother. 2006 50: 3917-3919. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Santiago Ramón-García, Isabel Otal, Carlos Martín, Rafael Gómez-Lus, and José A. Aínsa

Novel Streptomycin Resistance Gene from Mycobacterium fortuitum
Antimicrob. Agents Chemother. 2006 50: 3920-3922. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Timothy J. Johnson, Yvonne M. Wannemeuhler, Jennifer A. Scaccianoce, Sara J. Johnson, and Lisa K. Nolan

Complete DNA Sequence, Comparative Genomics, and Prevalence of an IncHI2 Plasmid Occurring among Extraintestinal Pathogenic Escherichia coli Isolates
Antimicrob. Agents Chemother. 2006 50: 3929-3933. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Anwar Ahmed, Vanshika Lumb, Manoj K. Das, Vas Dev, Wajihullah, and Yagya D. Sharma

Prevalence of Mutations Associated with Higher Levels of Sulfadoxine-Pyrimethamine Resistance in Plasmodium falciparum Isolates from Car Nicobar Island and Assam, India
Antimicrob. Agents Chemother. 2006 50: 3934-3938. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ebbing Lautenbach, Pam Tolomeo, Xiangqun Mao, Neil O. Fishman, Joshua P. Metlay, Warren B. Bilker, and Irving Nachamkin

Duration of Outpatient Fecal Colonization Due to Escherichia coli Isolates with Decreased Susceptibility to Fluoroquinolones: Longitudinal Study of Patients Recently Discharged from the Hospital
Antimicrob. Agents Chemother. 2006 50: 3939-3943. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Axel Cloeckaert, Karine Praud, Benoît Doublet, Marie Demartin, and François-Xavier Weill

Variant Salmonella Genomic Island 1-L Antibiotic Resistance Gene Cluster in Salmonella enterica Serovar Newport
Antimicrob. Agents Chemother. 2006 50: 3944-3946. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Chi Hye Park, Ari Robicsek, George A. Jacoby, Daniel Sahm, and David C. Hooper

Prevalence in the United States of aac(6')-Ib-cr Encoding a Ciprofloxacin-Modifying Enzyme
Antimicrob. Agents Chemother. 2006 50: 3953-3955. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Susceptibility:

Sachin S. Bhagwat, Lakshmi A. Mundkur, Shrikant V. Gupte, Mahesh V. Patel, and Habil F. Khorakiwala

The Anti-Methicillin-Resistant Staphylococcus aureus Quinolone WCK 771 Has Potent Activity against Sequentially Selected Mutants, Has a Narrow Mutant Selection Window against Quinolone-Resistant Staphylococcus aureus, and Preferentially Targets DNA Gyrase
Antimicrob. Agents Chemother. 2006 50: 3568-3579. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Sasinee Bunyarataphan, Ubolsree Leartsakulpanich, Supannee Taweechai, Bongkoch Tarnchompoo, Sumalee Kamchonwongpaisan, and Yongyuth Yuthavong

Evaluation of the Activities of Pyrimethamine Analogs against Plasmodium vivax and Plasmodium falciparum Dihydrofolate Reductase-Thymidylate Synthase Using In Vitro Enzyme Inhibition and Bacterial Complementation Assays
Antimicrob. Agents Chemother. 2006 50: 3631-3637. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Miika Bergman, Solja Huikko, Pentti Huovinen, Pirkko Paakkari, Helena Seppälä, and Finnish Study Group for Antimicrobial Resistance (FiRe Network)

Macrolide and Azithromycin Use Are Linked to Increased Macrolide Resistance in Streptococcus pneumoniae
Antimicrob. Agents Chemother. 2006 50: 3646-3650. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jeanette W. P. Teo, Pamela Thayalan, David Beer, Amelia S. L. Yap, Mahesh Nanjundappa, Xinyi Ngew, Jeyaraj Duraiswamy, Sarah Liung, Veronique Dartois, Mark Schreiber, Samiul Hasan, Michael Cynamon, Neil S. Ryder, Xia Yang, Beat Weidmann, Kathryn Bracken, Thomas Dick, and Kakoli Mukherjee

Peptide Deformylase Inhibitors as Potent Antimycobacterial Agents
Antimicrob. Agents Chemother. 2006 50: 3665-3673. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Arunasalam Naguleswaran, Martin Spicher, Nathalie Vonlaufen, Luis M. Ortega-Mora, Paul Torgerson, Bruno Gottstein, and Andrew Hemphill

In Vitro Metacestodicidal Activities of Genistein and Other Isoflavones against Echinococcus multilocularis and Echinococcus granulosus
Antimicrob. Agents Chemother. 2006 50: 3770-3778. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Cécile Ménez, Marion Buyse, Madeleine Besnard, Robert Farinotti, Philippe M. Loiseau, and Gillian Barratt

Interaction between Miltefosine and Amphotericin B: Consequences for Their Activities towards Intestinal Epithelial Cells and Leishmania donovani Promastigotes In Vitro
Antimicrob. Agents Chemother. 2006 50: 3793-3800. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Randal Eckert, Keith M. Brady, E. Peter Greenberg, Fengxia Qi, Daniel K. Yarbrough, Jian He, Ian McHardy, Maxwell H. Anderson, and Wenyuan Shi

Enhancement of Antimicrobial Activity against Pseudomonas aeruginosa by Coadministration of G10KHc and Tobramycin
Antimicrob. Agents Chemother. 2006 50: 3833-3838. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Stephen Rittenhouse, Sanjoy Biswas, John Broskey, Lynn McCloskey, Terrance Moore, Sandra Vasey, Joshua West, Magdalena Zalacain, Rimma Zonis, and David Payne

Selection of Retapamulin, a Novel Pleuromutilin for Topical Use
Antimicrob. Agents Chemother. 2006 50: 3882-3885. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Agam Rao, Robin L. P. Jump, Nicole J. Pultz, Michael J. Pultz, and Curtis J. Donskey

In Vitro Killing of Nosocomial Pathogens by Acid and Acidified Nitrite
Antimicrob. Agents Chemother. 2006 50: 3901-3904. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kaori Tanaka, Hiroshige Mikamo, Ken'ichi Nakao, and Kunitomo Watanabe

In Vitro Antianaerobic Activity of DX-619, a New Des-Fluoro(6) Quinolone
Antimicrob. Agents Chemother. 2006 50: 3908-3913. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Glenn A. Pankuch, Dianne Hoellman, André Bryskier, John Lowther, and Peter C. Appelbaum

Effects of Various Media on the Activity of NXL103 (Formerly XRP 2868), a New Oral Streptogramin, against Haemophilus influenzae
Antimicrob. Agents Chemother. 2006 50: 3914-3916. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Oscar Cirioni, Andrea Giacometti, Carmela Silvestri, Agnese Della Vittoria, Alberto Licci, Alessandra Riva, and Giorgio Scalise

In Vitro Activities of Tritrpticin Alone and in Combination with Other Antimicrobial Agents against Pseudomonas aeruginosa
Antimicrob. Agents Chemother. 2006 50: 3923-3925. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ellie J. C. Goldstein, Diane M. Citron, C. Vreni Merriam, Yumi A. Warren, Kerin L. Tyrrell, and Helen T. Fernandez

In Vitro Activity of Ceftobiprole against Aerobic and Anaerobic Strains Isolated from Diabetic Foot Infections
Antimicrob. Agents Chemother. 2006 50: 3959-3962. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Action:

Tulika Prasad, Aparna Chandra, Chinmay K. Mukhopadhyay, and Rajendra Prasad

Unexpected Link between Iron and Drug Resistance of Candida spp.: Iron Depletion Enhances Membrane Fluidity and Drug Diffusion, Leading to Drug-Susceptible Cells
Antimicrob. Agents Chemother. 2006 50: 3597-3606. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Bruno Périchon and Patrice Courvalin

Synergism between ß-Lactams and Glycopeptides against VanA-Type Methicillin-Resistant Staphylococcus aureus and Heterologous Expression of the vanA Operon
Antimicrob. Agents Chemother. 2006 50: 3622-3630. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Randal Eckert, Jian He, Daniel K. Yarbrough, Fengxia Qi, Maxwell H. Anderson, and Wenyuan Shi

Targeted Killing of Streptococcus mutans by a Pheromone-Guided "Smart" Antimicrobial Peptide
Antimicrob. Agents Chemother. 2006 50: 3651-3657. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ute Müh, Martin Schuster, Roger Heim, Ashvani Singh, Eric R. Olson, and E. Peter Greenberg

Novel Pseudomonas aeruginosa Quorum-Sensing Inhibitors Identified in an Ultra-High-Throughput Screen
Antimicrob. Agents Chemother. 2006 50: 3674-3679. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Vladimir A. Karginov, Ekaterina M. Nestorovich, Adiamseged Yohannes, Tanisha M. Robinson, Nour Eddine Fahmi, Frank Schmidtmann, Sidney M. Hecht, and Sergey M. Bezrukov

Search for Cyclodextrin-Based Inhibitors of Anthrax Toxins: Synthesis, Structural Features, and Relative Activities
Antimicrob. Agents Chemother. 2006 50: 3740-3753. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Yan Q. Xiong, Arnold S. Bayer, Lisa Elazegui, and Michael R. Yeaman

A Synthetic Congener Modeled on a Microbicidal Domain of Thrombin- Induced Platelet Microbicidal Protein 1 Recapitulates Staphylocidal Mechanisms of the Native Molecule
Antimicrob. Agents Chemother. 2006 50: 3786-3792. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Alberto Muñoz, Belén López-García, and Jose F. Marcos

Studies on the Mode of Action of the Antifungal Hexapeptide PAF26
Antimicrob. Agents Chemother. 2006 50: 3847-3855. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kang Yan, Lenore Madden, Anthony E. Choudhry, Christine S. Voigt, Robert A. Copeland, and Richard R. Gontarek

Biochemical Characterization of the Interactions of the Novel Pleuromutilin Derivative Retapamulin with Bacterial Ribosomes
Antimicrob. Agents Chemother. 2006 50: 3875-3881. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

G. A. Pankuch and P. C. Appelbaum

Postantibiotic Effect of Ceftobiprole against 12 Gram-Positive Organisms
Antimicrob. Agents Chemother. 2006 50: 3956-3958. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Antiviral Agents:

Peter R. Meyer, Anthony J. Smith, Suzanne E. Matsuura, and Walter A. Scott

Chain-Terminating Dinucleoside Tetraphosphates Are Substrates for DNA Polymerization by Human Immunodeficiency Virus Type 1 Reverse Transcriptase with Increased Activity against Thymidine Analogue-Resistant Mutants
Antimicrob. Agents Chemother. 2006 50: 3607-3614. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Qing Ge, Manoj Pastey, Darwyn Kobasa, Piliapan Puthavathana, Christopher Lupfer, Richard K. Bestwick, Patrick L. Iversen, Jianzhu Chen, and David A. Stein

Inhibition of Multiple Subtypes of Influenza A Virus in Cell Cultures with Morpholino Oligomers
Antimicrob. Agents Chemother. 2006 50: 3724-3733. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

M. A. Rameix-Welti, F. Agou, P. Buchy, S. Mardy, J. T. Aubin, M. Véron, S. van der Werf, and N. Naffakh

Natural Variation Can Significantly Alter the Sensitivity of Influenza A (H5N1) Viruses to Oseltamivir
Antimicrob. Agents Chemother. 2006 50: 3809-3815. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Francesc Vidal, Joan Carles Domingo, Jordi Guallar, Maria Saumoy, Begoña Cordobilla, Rainel Sánchez de la Rosa, Marta Giralt, Maria Luisa Álvarez, Miguel López-Dupla, Ferran Torres, Francesc Villarroya, Tomas Cihlar, and Pere Domingo

In Vitro Cytotoxicity and Mitochondrial Toxicity of Tenofovir Alone and in Combination with Other Antiretrovirals in Human Renal Proximal Tubule Cells
Antimicrob. Agents Chemother. 2006 50: 3824-3832. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hiromi Yatsuji, Chiemi Noguchi, Nobuhiko Hiraga, Nami Mori, Masataka Tsuge, Michio Imamura, Shoichi Takahashi, Eiji Iwao, Yoshifumi Fujimoto, Hidenori Ochi, Hiromi Abe, Toshiro Maekawa, Chise Tateno, Katsutoshi Yoshizato, Fumitaka Suzuki, Hiromitsu Kumada, and Kazuaki Chayama

Emergence of a Novel Lamivudine-Resistant Hepatitis B Virus Variant with a Substitution Outside the YMDD Motif
Antimicrob. Agents Chemother. 2006 50: 3867-3874. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Yan Sergerie and Guy Boivin

Thymidine Kinase Mutations Conferring Acyclovir Resistance in Herpes Simplex Type 1 Recombinant Viruses
Antimicrob. Agents Chemother. 2006 50: 3889-3892. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Letters:

Koichi Tanimoto, Takahiro Nomura, Hideyuki Maruyama, Haruyoshi Tomita, Naohiro Shibata, Yoshichika Arakawa, and Yasuyoshi Ike

First VanD-Type Vancomycin-Resistant Enterococcus raffinosus Isolate
Antimicrob. Agents Chemother. 2006 50: 3966-3967. [Full Text] [PDF] [Reprints and Permissions]  

Caitlin Reed, Ashraf Ibrahim, John E. Edwards, Jr., Irwin Walot, and Brad Spellberg

Deferasirox, an Iron-Chelating Agent, as Salvage Therapy for Rhinocerebral Mucormycosis
Antimicrob. Agents Chemother. 2006 50: 3968-3969. [Full Text] [PDF] [Reprints and Permissions]  

Errata:

Vívian de F. Sumnienski Rodrigues, Maria Alice Telles, Marta Osório Ribeiro, Patrícia Izquierdo Cafrune, Maria Lucia Rosa Rossetti, and Arnaldo Zaha

Characterization of pncA Mutations in Pyrazinamide-Resistant Mycobacterium tuberculosis in Brazil
Antimicrob. Agents Chemother. 2006 50: 3970. [Full Text] [PDF] [Reprints and Permissions]  

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