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Clinical Therapeutics:

S. M. Graham, D. J. Bell, S. Nyirongo, R. Hartkoorn, S. A. Ward, and E. M. Molyneux

Low Levels of Pyrazinamide and Ethambutol in Children with Tuberculosis and Impact of Age, Nutritional Status, and Human Immunodeficiency Virus Infection
Antimicrob. Agents Chemother. 2006 50: 407-413. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mario Tumbarello, Teresa Spanu, Maurizio Sanguinetti, Rita Citton, Eva Montuori, Fiammetta Leone, Giovanni Fadda, and Roberto Cauda

Bloodstream Infections Caused by Extended-Spectrum-ß-Lactamase-Producing Klebsiella pneumoniae: Risk Factors, Molecular Epidemiology, and Clinical Outcome
Antimicrob. Agents Chemother. 2006 50: 498-504. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

A. J. Ullmann, O. A. Cornely, A. Burchardt, R. Hachem, D. P. Kontoyiannis, K. Töpelt, R. Courtney, D. Wexler, G. Krishna, M. Martinho, G. Corcoran, and I. Raad

Pharmacokinetics, Safety, and Efficacy of Posaconazole in Patients with Persistent Febrile Neutropenia or Refractory Invasive Fungal Infection
Antimicrob. Agents Chemother. 2006 50: 658-666. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Satowa Suzuki, Tsutomu Yamazaki, Mitsuo Narita, Norio Okazaki, Isao Suzuki, Tomoaki Andoh, Mayumi Matsuoka, Tsuyoshi Kenri, Yoshichika Arakawa, and Tsuguo Sasaki

Clinical Evaluation of Macrolide-Resistant Mycoplasma pneumoniae
Antimicrob. Agents Chemother. 2006 50: 709-712. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Experimental Therapeutics:

Fred Widmer, Lesley C. Wright, Daniel Obando, Rosemary Handke, Ranjini Ganendren, David H. Ellis, and Tania C. Sorrell

Hexadecylphosphocholine (Miltefosine) Has Broad-Spectrum Fungicidal Activity and Is Efficacious in a Mouse Model of Cryptococcosis
Antimicrob. Agents Chemother. 2006 50: 414-421. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Carly G. Dennis, William R. Greco, Yseult Brun, Richard Youn, Harry K. Slocum, Ralph J. Bernacki, Russell Lewis, Nathan Wiederhold, Steven M. Holland, Ruta Petraitiene, Thomas J. Walsh, and Brahm H. Segal

Effect of Amphotericin B and Micafungin Combination on Survival, Histopathology, and Fungal Burden in Experimental Aspergillosis in the p47^phox–/– Mouse Model of Chronic Granulomatous Disease
Antimicrob. Agents Chemother. 2006 50: 422-427. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Nathan P. Wiederhold, Vincent H. Tam, Jingduan Chi, Randall A. Prince, Dimitrios P. Kontoyiannis, and Russell E. Lewis

Pharmacodynamic Activity of Amphotericin B Deoxycholate Is Associated with Peak Plasma Concentrations in a Neutropenic Murine Model of Invasive Pulmonary Aspergillosis
Antimicrob. Agents Chemother. 2006 50: 469-473. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

John H. Vernachio, Arnold S. Bayer, Brenda Ames, Dawn Bryant, Bradley D. Prater, Peter J. Syribeys, Elena L. Gorovits, and Joseph M. Patti

Human Immunoglobulin G Recognizing Fibrinogen-Binding Surface Proteins Is Protective against both Staphylococcus aureus and Staphylococcus epidermidis Infections In Vivo
Antimicrob. Agents Chemother. 2006 50: 511-518. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

George Athanassopoulos, Angelos Pefanis, Vissaria Sakka, Dimitrios Iliopoulos, Despina Perrea, and Helen Giamarellou

Linezolid in Prophylaxis against Experimental Aortic Valve Endocarditis Due to Streptococcus oralis or Enterococcus faecalis
Antimicrob. Agents Chemother. 2006 50: 654-657. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

D. Andes, N. Safdar, K. Marchillo, and R. Conklin

Pharmacokinetic-Pharmacodynamic Comparison of Amphotericin B (AMB) and Two Lipid-Associated AMB Preparations, Liposomal AMB and AMB Lipid Complex, in Murine Candidiasis Models
Antimicrob. Agents Chemother. 2006 50: 674-684. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Katsuhiko Hayashi, Shin-etsu Kadowaki, Masaya Takei, and Hideyuki Fukuda

Efficacy of Quinolones against Secondary Pneumococcal Pneumonia after Influenza Virus Infection in Mice
Antimicrob. Agents Chemother. 2006 50: 748-751. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Armin Stucki, Peter Gerber, Fernando Acosta, Marianne Cottagnoud, and Philippe Cottagnoud

Efficacy of Telavancin against Penicillin-Resistant Pneumococci and Staphylococcus aureus in a Rabbit Meningitis Model and Determination of Kinetic Parameters
Antimicrob. Agents Chemother. 2006 50: 770-773. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kimberly D. Leuthner, Chrissy M. Cheung, and Michael J. Rybak

Pulsatile Delivery of Clarithromycin Alone or in Combination with Amoxicillin against Streptococcus pneumoniae
Antimicrob. Agents Chemother. 2006 50: 813-816. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Resistance:

Longzhu Cui, Akira Iwamoto, Jian-Qi Lian, Hui-min Neoh, Toshiki Maruyama, Yataro Horikawa, and Keiichi Hiramatsu

Novel Mechanism of Antibiotic Resistance Originating in Vancomycin-Intermediate Staphylococcus aureus
Antimicrob. Agents Chemother. 2006 50: 428-438. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Daniel Criswell, Virginia L. Tobiason, J. Stephen Lodmell, and D. Scott Samuels

Mutations Conferring Aminoglycoside and Spectinomycin Resistance in Borrelia burgdorferi
Antimicrob. Agents Chemother. 2006 50: 445-452. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Laura Alcazar-Fuoli, Emilia Mellado, Guillermo Garcia-Effron, Maria J. Buitrago, Jordi F. Lopez, Joan O. Grimalt, J. Manuel Cuenca-Estrella, and Juan L. Rodriguez-Tudela

Aspergillus fumigatus C-5 Sterol Desaturases Erg3A and Erg3B: Role in Sterol Biosynthesis and Antifungal Drug Susceptibility
Antimicrob. Agents Chemother. 2006 50: 453-460. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Gerard A. Cangelosi, Julie S. Do, Robert Freeman, John G. Bennett, Makeda Semret, and Marcel A. Behr

The Two-Component Regulatory System mtrAB Is Required for Morphotypic Multidrug Resistance in Mycobacterium avium
Antimicrob. Agents Chemother. 2006 50: 461-468. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

A. Afonso, P. Hunt, S. Cheesman, A. C. Alves, C. V. Cunha, V. do Rosário, and P. Cravo

Malaria Parasites Can Develop Stable Resistance to Artemisinin but Lack Mutations in Candidate Genes atp6 (Encoding the Sarcoplasmic and Endoplasmic Reticulum Ca²⁺ ATPase), tctp, mdr1, and cg10
Antimicrob. Agents Chemother. 2006 50: 480-489. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

C. Hal Jones, Margareta Tuckman, Anita Y. M. Howe, Mark Orlowski, Stanley Mullen, Karen Chan, and Patricia A. Bradford

Diagnostic PCR Analysis of the Occurrence of Methicillin and Tetracycline Resistance Genes among Staphylococcus aureus Isolates from Phase 3 Clinical Trials of Tigecycline for Complicated Skin and Skin Structure Infections
Antimicrob. Agents Chemother. 2006 50: 505-510. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Krzysztof Sieradzki and Alexander Tomasz

Inhibition of the Autolytic System by Vancomycin Causes Mimicry of Vancomycin-Intermediate Staphylococcus aureus-Type Resistance, Cell Concentration Dependence of the MIC, and Antibiotic Tolerance in Vancomycin-Susceptible S. aureus
Antimicrob. Agents Chemother. 2006 50: 527-533. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jun-ichi Wachino, Hiroshi Kurokawa, Satowa Suzuki, Kunikazu Yamane, Naohiro Shibata, Kouji Kimura, Yasuyoshi Ike, and Yoshichika Arakawa

Horizontal Transfer of bla_CMY-Bearing Plasmids among Clinical Escherichia coli and Klebsiella pneumoniae Isolates and Emergence of Cefepime-Hydrolyzing CMY-19
Antimicrob. Agents Chemother. 2006 50: 534-541. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Taiga Miyazaki, Yoshitsugu Miyazaki, Koichi Izumikawa, Hiroshi Kakeya, Shunichi Miyakoshi, John E. Bennett, and Shigeru Kohno

Fluconazole Treatment Is Effective against a Candida albicans erg3/erg3 Mutant In Vivo Despite In Vitro Resistance
Antimicrob. Agents Chemother. 2006 50: 580-586. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Camilla H. Lester, Niels Frimodt-Møller, Thomas Lund Sørensen, Dominique L. Monnet, and Anette M. Hammerum

In Vivo Transfer of the vanA Resistance Gene from an Enterococcus faecium Isolate of Animal Origin to an E. faecium Isolate of Human Origin in the Intestines of Human Volunteers
Antimicrob. Agents Chemother. 2006 50: 596-599. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jacob Strahilevitz, Ari Robicsek, and David C. Hooper

Role of the Extended 4 Domain of Staphylococcus aureus Gyrase A Protein in Determining Low Sensitivity to Quinolones
Antimicrob. Agents Chemother. 2006 50: 600-606. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Charlotte Verdet, Yahia Benzerara, Valérie Gautier, Olivier Adam, Zahia Ould-Hocine, and Guillaume Arlet

Emergence of DHA-1-Producing Klebsiella spp. in the Parisian Region: Genetic Organization of the ampC and ampR Genes Originating from Morganella morganii
Antimicrob. Agents Chemother. 2006 50: 607-617. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Marco M. D'Andrea, Elisabetta Nucleo, Francesco Luzzaro, Tommaso Giani, Roberta Migliavacca, Francesca Vailati, Vesselina Kroumova, Laura Pagani, and Gian Maria Rossolini

CMY-16, a Novel Acquired AmpC-Type ß-Lactamase of the CMY/LAT Lineage in Multifocal Monophyletic Isolates of Proteus mirabilis from Northern Italy
Antimicrob. Agents Chemother. 2006 50: 618-624. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Estelle Marrer, Karen Schad, Andreas T. Satoh, Malcolm G. P. Page, Maggie M. Johnson, and Laura J. V. Piddock

Involvement of the Putative ATP-Dependent Efflux Proteins PatA and PatB in Fluoroquinolone Resistance of a Multidrug-Resistant Mutant of Streptococcus pneumoniae
Antimicrob. Agents Chemother. 2006 50: 685-693. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mónica Blanco, César B. Gutiérrez-Martin, Elías F. Rodríguez-Ferri, Marilyn C. Roberts, and Jesús Navas

Distribution of Tetracycline Resistance Genes in Actinobacillus pleuropneumoniae Isolates from Spain
Antimicrob. Agents Chemother. 2006 50: 702-708. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

J. Delmas, F. Robin, F. Carvalho, C. Mongaret, and R. Bonnet

Prediction of the Evolution of Ceftazidime Resistance in Extended-Spectrum ß-Lactamase CTX-M-9
Antimicrob. Agents Chemother. 2006 50: 731-738. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Juliana Coelho, Neil Woodford, Mariya Afzal-Shah, and David Livermore

Occurrence of OXA-58-Like Carbapenemases in Acinetobacter spp. Collected over 10 Years in Three Continents
Antimicrob. Agents Chemother. 2006 50: 756-758. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Klaudia Kosowska-Shick, Catherine Clark, Kim Credito, Pamela McGhee, Bonifacio Dewasse, Tatiana Bogdanovich, and Peter C. Appelbaum

Single- and Multistep Resistance Selection Studies on the Activity of Retapamulin Compared to Other Agents against Staphylococcus aureus and Streptococcus pyogenes
Antimicrob. Agents Chemother. 2006 50: 765-769. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Rafael Vignoli, Nicolas F. Cordeiro, Virginia García, María Inés Mota, Laura Betancor, Pablo Power, José A. Chabalgoity, Felipe Schelotto, Gabriel Gutkind, and Juan A. Ayala

New TEM-Derived Extended-Spectrum ß-Lactamase and Its Genomic Context in Plasmids from Salmonella enterica Serovar Derby Isolates from Uruguay
Antimicrob. Agents Chemother. 2006 50: 781-784. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Alexandra Eisner, Elizabeth J. Fagan, Gebhard Feierl, Harald H. Kessler, Egon Marth, David M. Livermore, and Neil Woodford

Emergence of Enterobacteriaceae Isolates Producing CTX-M Extended-Spectrum ß-Lactamase in Austria
Antimicrob. Agents Chemother. 2006 50: 785-787. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Naohiro Shibata, Hiroshi Kurokawa, Yohei Doi, Tetsuya Yagi, Kunikazu Yamane, Jun-ichi Wachino, Satowa Suzuki, Kouji Kimura, Satoshi Ishikawa, Haru Kato, Yoshiyuki Ozawa, Keigo Shibayama, Kumiko Kai, Toshifumi Konda, and Yoshichika Arakawa

PCR Classification of CTX-M-Type ß-Lactamase Genes Identified in Clinically Isolated Gram-Negative Bacilli in Japan
Antimicrob. Agents Chemother. 2006 50: 791-795. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Aránzazu Valverde, Rafael Cantón, Juan Carlos Galán, Patrice Nordmann, Fernando Baquero, and Teresa M. Coque

In117, an Unusual In0-Like Class 1 Integron Containing CR1 and bla_CTX-M-2 and Associated with a Tn21-Like Element
Antimicrob. Agents Chemother. 2006 50: 799-802. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

David J. Farrell, Jemma Shackcloth, Karen A. Barbadora, and Michael D. Green

Streptococcus pyogenes Isolates with High-Level Macrolide Resistance and Reduced Susceptibility to Telithromycin Associated with 23S rRNA Mutations
Antimicrob. Agents Chemother. 2006 50: 817-818. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Action:

Robert J. Suchland, Kara Brown, David M. Rothstein, and Walter E. Stamm

Rifalazil Pretreatment of Mammalian Cell Cultures Prevents Subsequent Chlamydia Infection
Antimicrob. Agents Chemother. 2006 50: 439-444. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Tali Rydlo, Shahar Rotem, and Amram Mor

Antibacterial Properties of Dermaseptin S4 Derivatives under Extreme Incubation Conditions
Antimicrob. Agents Chemother. 2006 50: 490-497. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Katherine Young, Hiranthi Jayasuriya, John G. Ondeyka, Kithsiri Herath, Chaowei Zhang, Srinivas Kodali, Andrew Galgoci, Ronald Painter, Vickie Brown-Driver, Robert Yamamoto, Lynn L. Silver, Yingcong Zheng, Judith I. Ventura, Janet Sigmund, Sookhee Ha, Angela Basilio, Francisca Vicente, José Rubén Tormo, Fernando Pelaez, Phil Youngman, Doris Cully, John F. Barrett, Dennis Schmatz, Sheo B. Singh, and Jun Wang

Discovery of FabH/FabF Inhibitors from Natural Products
Antimicrob. Agents Chemother. 2006 50: 519-526. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hyun Koo, Jennifer Seils, Jacqueline Abranches, Robert A. Burne, William H. Bowen, and Robert G. Quivey, Jr.

Influence of Apigenin on gtf Gene Expression in Streptococcus mutans UA159
Antimicrob. Agents Chemother. 2006 50: 542-546. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Youjun Yang, Anatoly Severin, Rajiv Chopra, Girija Krishnamurthy, Guy Singh, William Hu, David Keeney, Kristine Svenson, Peter J. Petersen, Pornpen Labthavikul, David M. Shlaes, Beth A. Rasmussen, Amedeo A. Failli, Jay S. Shumsky, Kristina M. K. Kutterer, Adam Gilbert, and Tarek S. Mansour

3,5-Dioxopyrazolidines, Novel Inhibitors of UDP-N- Acetylenolpyruvylglucosamine Reductase (MurB) with Activity against Gram-Positive Bacteria
Antimicrob. Agents Chemother. 2006 50: 556-564. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mark C. Wagner, Elizabeth E. Molnar, Bruce A. Molitoris, and Mark G. Goebl

Loss of the Homotypic Fusion and Vacuole Protein Sorting or Golgi-Associated Retrograde Protein Vesicle Tethering Complexes Results in Gentamicin Sensitivity in the Yeast Saccharomyces cerevisiae
Antimicrob. Agents Chemother. 2006 50: 587-595. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

S. M. Soto, M. T. Jimenez de Anta, and J. Vila

Quinolones Induce Partial or Total Loss of Pathogenicity Islands in Uropathogenic Escherichia coli by SOS-Dependent or -Independent Pathways, Respectively
Antimicrob. Agents Chemother. 2006 50: 649-653. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Matthias Dormeyer, Yvonne Adams, Bernd Kramer, Srabasti Chakravorty, Man Tsuey Tse, Stefano Pegoraro, Lisa Whittaker, Michael Lanzer, and Alister Craig

Rational Design of Anticytoadherence Inhibitors for Plasmodium falciparum Based on the Crystal Structure of Human Intercellular Adhesion Molecule 1
Antimicrob. Agents Chemother. 2006 50: 724-730. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Masaki Fujita, Qing Ye, Hiroshi Ouchi, Eiji Harada, Ichiro Inoshima, Kazuyoshi Kuwano, and Yoichi Nakanishi

Doxycycline Attenuated Pulmonary Fibrosis Induced by Bleomycin in Mice
Antimicrob. Agents Chemother. 2006 50: 739-743. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Georgios Chamilos, Russell E. Lewis, and Dimitrios P. Kontoyiannis

Inhibition of Candida parapsilosis Mitochondrial Respiratory Pathways Enhances Susceptibility to Caspofungin
Antimicrob. Agents Chemother. 2006 50: 744-747. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jennifer Keiser, Reto Brun, Bernard Fried, and Jürg Utzinger

Trematocidal Activity of Praziquantel and Artemisinin Derivatives: In Vitro and In Vivo Investigations with Adult Echinostoma caproni
Antimicrob. Agents Chemother. 2006 50: 803-805. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Inshad Ali Khan, Zahid Mehmood Mirza, Ashwani Kumar, Vijeshwar Verma, and Ghulam Nabi Qazi

Piperine, a Phytochemical Potentiator of Ciprofloxacin against Staphylococcus aureus
Antimicrob. Agents Chemother. 2006 50: 810-812. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Chemistry; Biosynthesis:

Stephanie St. George, Jeanette V. Bishop, Richard G. Titus, and Claude P. Selitrennikoff

Novel Compounds Active against Leishmania major
Antimicrob. Agents Chemother. 2006 50: 474-479. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Antiviral Agents:

Ann Florence B. Victoriano, Kaori Asamitsu, Yurina Hibi, Kenichi Imai, Nina G. Barzaga, and Takashi Okamoto

Inhibition of Human Immunodeficiency Virus Type 1 Replication in Latently Infected Cells by a Novel IB Kinase Inhibitor
Antimicrob. Agents Chemother. 2006 50: 547-555. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Valérie Cottier, Alcide Barberis, and Urs Lüthi

Novel Yeast Cell-Based Assay To Screen for Inhibitors of Human Cytomegalovirus Protease in a High-Throughput Format
Antimicrob. Agents Chemother. 2006 50: 565-571. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Z. Gu, B. Allard, J. M. de Muys, J. Lippens, R. F. Rando, N. Nguyen-Ba, C. Ren, P. McKenna, D. L. Taylor, and R. C. Bethell

In Vitro Antiretroviral Activity and In Vitro Toxicity Profile of SPD754, a New Deoxycytidine Nucleoside Reverse Transcriptase Inhibitor for Treatment of Human Immunodeficiency Virus Infection
Antimicrob. Agents Chemother. 2006 50: 625-631. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Joke Snoeck, Rami Kantor, Robert W. Shafer, Kristel Van Laethem, Koen Deforche, Ana Patricia Carvalho, Brian Wynhoven, Marcelo A. Soares, Patricia Cane, John Clarke, Candice Pillay, Sunee Sirivichayakul, Koya Ariyoshi, Africa Holguin, Hagit Rudich, Rosangela Rodrigues, Maria Belen Bouzas, Françoise Brun-Vézinet, Caroline Reid, Pedro Cahn, Luis Fernando Brigido, Zehava Grossman, Vincent Soriano, Wataru Sugiura, Praphan Phanuphak, Lynn Morris, Jonathan Weber, Deenan Pillay, Amilcar Tanuri, Richard P. Harrigan, Ricardo Camacho, Jonathan M. Schapiro, David Katzenstein, and Anne-Mieke Vandamme

Discordances between Interpretation Algorithms for Genotypic Resistance to Protease and Reverse Transcriptase Inhibitors of Human Immunodeficiency Virus Are Subtype Dependent
Antimicrob. Agents Chemother. 2006 50: 694-701. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Brigitte E. Beer, Gustavo F. Doncel, Fred C. Krebs, Robin J. Shattock, Patricia S. Fletcher, Robert W. Buckheit, Jr., Karen Watson, Charlene S. Dezzutti, James E. Cummins, Ena Bromley, Nicola Richardson-Harman, Luke A. Pallansch, Carol Lackman-Smith, Clay Osterling, Marie Mankowski, Shendra R. Miller, Bradley J. Catalone, Patricia A. Welsh, Mary K. Howett, Brian Wigdahl, Jim A. Turpin, and Patricia Reichelderfer

In Vitro Preclinical Testing of Nonoxynol-9 as Potential Anti-Human Immunodeficiency Virus Microbicide: a Retrospective Analysis of Results from Five Laboratories
Antimicrob. Agents Chemother. 2006 50: 713-723. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

David A. Kocisko, Winslow S. Caughey, Richard E. Race, Grant Roper, Byron Caughey, and John D. Morrey

A Porphyrin Increases Survival Time of Mice after Intracerebral Prion Infection
Antimicrob. Agents Chemother. 2006 50: 759-761. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Dale J. Kempf, Jeffrey F. Waring, David C. Morfitt, Paige Werner, Brian Ebert, Michael Mitten, Bach Nguyen, John T. Randolph, David A. DeGoey, Larry L. Klein, and Kennan Marsh

Practical Preclinical Model for Assessing the Potential for Unconjugated Hyperbilirubinemia Produced by Human Immunodeficiency Virus Protease Inhibitors
Antimicrob. Agents Chemother. 2006 50: 762-764. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Marie-Ève Hamelin, Gregory A. Prince, and Guy Boivin

Effect of Ribavirin and Glucocorticoid Treatment in a Mouse Model of Human Metapneumovirus Infection
Antimicrob. Agents Chemother. 2006 50: 774-777. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Susceptibility:

Emmanuelle Varon, Serge Houssaye, Sophie Grondin, Laurent Gutmann the Groupe des Observatoires de la Résistance du Pneumocoque

Nonmolecular Test for Detection of Low-Level Resistance to Fluoroquinolones in Streptococcus pneumoniae
Antimicrob. Agents Chemother. 2006 50: 572-579. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Katherine T. Andrews, David P. Fairlie, Praveen K. Madala, John Ray, David M. Wyatt, Petrina M. Hilton, Lewis A. Melville, Lynette Beattie, Donald L. Gardiner, Robert C. Reid, Martin J. Stoermer, Tina Skinner-Adams, Colin Berry, and James S. McCarthy

Potencies of Human Immunodeficiency Virus Protease Inhibitors In Vitro against Plasmodium falciparum and In Vivo against Murine Malaria
Antimicrob. Agents Chemother. 2006 50: 639-648. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Paul D. Stapleton, Saroj Shah, Yukihiko Hara, and Peter W. Taylor

Potentiation of Catechin Gallate-Mediated Sensitization of Staphylococcus aureus to Oxacillin by Nongalloylated Catechins
Antimicrob. Agents Chemother. 2006 50: 752-755. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Veronica N. Kos, Monika Keelan, and Diane E. Taylor

Antimicrobial Susceptibilities of Campylobacter jejuni Isolates from Poultry from Alberta, Canada
Antimicrob. Agents Chemother. 2006 50: 778-780. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Paul A. Wickman, Ellen Smith Moland, Jennifer A. Black, and Kenneth S. Thomson

In Vitro Activity of DX-619, a Novel Des-Fluoro(6) Quinolone, against a Panel of Streptococcus pneumoniae Mutants with Characterized Resistance Mechanisms
Antimicrob. Agents Chemother. 2006 50: 796-798. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Giuseppantonio Maisetta, Giovanna Batoni, Semih Esin, Walter Florio, Daria Bottai, Flavia Favilli, and Mario Campa

In Vitro Bactericidal Activity of Human ß-Defensin 3 against Multidrug-Resistant Nosocomial Strains
Antimicrob. Agents Chemother. 2006 50: 806-809. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

M. M. Traczewski and S. D. Brown

In Vitro Activity of Doripenem against Pseudomonas aeruginosa and Burkholderia cepacia Isolates from both Cystic Fibrosis and Non-Cystic Fibrosis Patients
Antimicrob. Agents Chemother. 2006 50: 819-821. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pharmacology:

Daniel K. Benjamin, Jr., Timothy Driscoll, Nita L. Seibel, Corina E. Gonzalez, Maureen M. Roden, Rahki Kilaru, Kay Clark, James A. Dowell, Jennifer Schranz, and Thomas J. Walsh

Safety and Pharmacokinetics of Intravenous Anidulafungin in Children with Neutropenia at High Risk for Invasive Fungal Infections
Antimicrob. Agents Chemother. 2006 50: 632-638. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hartmut Stocker, Charlotte Kloft, Nele Plock, Antje Breske, Guido Kruse, Christian Herzmann, Hubert Schulbin, Peter Kreckel, Christoph Weber, Frank Goebel, Joerg Roeling, Schlomo Staszewski, Andreas Plettenberg, Christiane Moecklinghoff, Keikawus Arastéh, and Michael Kurowski

Pharmacokinetics of Enfuvirtide in Patients Treated in Typical Routine Clinical Settings
Antimicrob. Agents Chemother. 2006 50: 667-673. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Heather K. Sun, Kenneth Duchin, Charles H. Nightingale, Jeng-Pyng Shaw, Julie Seroogy, and David P. Nicolau

Tissue Penetration of Telavancin after Intravenous Administration in Healthy Subjects
Antimicrob. Agents Chemother. 2006 50: 788-790. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Letters:

Rovina Ruslami, Hanneke Nijland, Rob Aarnoutse, Bachti Alisjahbana, Arto Yuwono Soeroto, Suzanne Ewalds, and Reinout van Crevel

Evaluation of High- versus Standard-Dose Rifampin in Indonesian Patients with Pulmonary Tuberculosis
Antimicrob. Agents Chemother. 2006 50: 822-823. [Full Text] [PDF] [Reprints and Permissions]  

Ali Hassoun, Richard Spera, and John Dunkel

Tularemia and Once-Daily Gentamicin
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