To see an article, click its [Full Text], [Abstract] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

Clinical Therapeutics:

Elizabeth A. Ashley, Kasia Stepniewska, Niklas Lindegårdh, Rose McGready, Robert Hutagalung, Rae Hae, Pratap Singhasivanon, Nicholas J. White, and François Nosten

Population Pharmacokinetic Assessment of a New Regimen of Mefloquine Used in Combination Treatment of Uncomplicated Falciparum Malaria
Antimicrob. Agents Chemother. 2006 50: 2281-2285. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jennifer Buur, Ronald Baynes, Geof Smith, and Jim Riviere

Use of Probabilistic Modeling within a Physiologically Based Pharmacokinetic Model To Predict Sulfamethazine Residue Withdrawal Times in Edible Tissues in Swine
Antimicrob. Agents Chemother. 2006 50: 2344-2351. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Cornelia Buerger, Nele Plock, Pejman Dehghanyar, Christian Joukhadar, and Charlotte Kloft

Pharmacokinetics of Unbound Linezolid in Plasma and Tissue Interstitium of Critically Ill Patients after Multiple Dosing Using Microdialysis
Antimicrob. Agents Chemother. 2006 50: 2455-2463. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Susceptibility:

M. R. Stegemann, C. A. Passmore, J. Sherington, C. J. Lindeman, G. Papp, D. J. Weigel, and T. L. Skogerboe

Antimicrobial Activity and Spectrum of Cefovecin, a New Extended- Spectrum Cephalosporin, against Pathogens Collected from Dogs and Cats in Europe and North America
Antimicrob. Agents Chemother. 2006 50: 2286-2292. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Tatiana Bogdanovich, Kathy A. Smith, Catherine Clark, Glenn A. Pankuch, Gengrong Lin, Pamela McGhee, Bonifacio Dewasse, and Peter C. Appelbaum

Activity of LBM415 Compared to Those of 11 Other Agents against Haemophilus Species
Antimicrob. Agents Chemother. 2006 50: 2323-2329. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Helio S. Sader, Thomas R. Fritsche, and Ronald N. Jones

Daptomycin Bactericidal Activity and Correlation between Disk and Broth Microdilution Method Results in Testing of Staphylococcus aureus Strains with Decreased Susceptibility to Vancomycin
Antimicrob. Agents Chemother. 2006 50: 2330-2336. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

E. Dannaoui, M. Abdul, M. Arpin, A. Michel-Nguyen, M. A. Piens, A. Favel, O. Lortholary, F. Dromer, and the French Cryptococcosis Study Group

Results Obtained with Various Antifungal Susceptibility Testing Methods Do Not Predict Early Clinical Outcome in Patients with Cryptococcosis
Antimicrob. Agents Chemother. 2006 50: 2464-2470. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Morgan Hakki, Janet F. Staab, and Kieren A. Marr

Emergence of a Candida krusei Isolate with Reduced Susceptibility to Caspofungin during Therapy
Antimicrob. Agents Chemother. 2006 50: 2522-2524. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Todd A. Davies, Wenchi Shang, and Karen Bush

Activities of Ceftobiprole and Other ß-Lactams against Streptococcus pneumoniae Clinical Isolates from the United States with Defined Substitutions in Penicillin-Binding Proteins PBP 1a, PBP 2b, and PBP 2x
Antimicrob. Agents Chemother. 2006 50: 2530-2532. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Matthew E. Falagas, Patra K. Koletsi, Petros Kopterides, and Argyris Michalopoulos

Risk Factors for Isolation of Strains Susceptible Only to Polymyxin among Patients with Pseudomonas aeruginosa Bacteremia
Antimicrob. Agents Chemother. 2006 50: 2541-2543. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Cornelius J. Clancy, Hong Huang, Shaoji Cheng, Hartmut Derendorf, and M. Hong Nguyen

Characterizing the Effects of Caspofungin on Candida albicans, Candida parapsilosis, and Candida glabrata Isolates by Simultaneous Time-Kill and Postantifungal-Effect Experiments
Antimicrob. Agents Chemother. 2006 50: 2569-2572. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ronald N. Jones, Thomas R. Fritsche, Helio S. Sader, and James E. Ross

Activity of Retapamulin (SB-275833), a Novel Pleuromutilin, against Selected Resistant Gram-Positive Cocci
Antimicrob. Agents Chemother. 2006 50: 2583-2586. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pharmacology:

Michael Mulheran, Pauline Hyman-Taylor, Kelvin H.-V. Tan, Sarah Lewis, David Stableforth, Alan Knox, and Alan Smyth

Absence of Cochleotoxicity Measured by Standard and High-Frequency Pure Tone Audiometry in a Trial of Once- versus Three-Times-Daily Tobramycin in Cystic Fibrosis Patients
Antimicrob. Agents Chemother. 2006 50: 2293-2299. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Eric Giannoni, Philippe Moreillon, Jacques Cotting, Adrien Moessinger, Jacques Bille, Laurent Décosterd, Giorgio Zanetti, Paul Majcherczyk, and Denis Bugnon

Prospective Determination of Plasma Imipenem Concentrations in Critically Ill Children
Antimicrob. Agents Chemother. 2006 50: 2563-2568. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Resistance:

Davina Hiller, Stephanie Stahl, and Joachim Morschhäuser

Multiple cis-Acting Sequences Mediate Upregulation of the MDR1 Efflux Pump in a Fluconazole-Resistant Clinical Candida albicans Isolate
Antimicrob. Agents Chemother. 2006 50: 2300-2308. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Frédéric Robin, Julien Delmas, Maryse Archambaud, Cédric Schweitzer, Catherine Chanal, and Richard Bonnet

CMT-Type ß-Lactamase TEM-125, an Emerging Problem for Extended-Spectrum ß-Lactamase Detection
Antimicrob. Agents Chemother. 2006 50: 2403-2408. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Vijaya Bharathi Srinivasan, Rupinder Kaur Virk, Amita Kaundal, Rupa Chakraborty, Basabjit Datta, T. Ramamurthy, Asish K. Mukhopadhyay, and Amit Ghosh

Mechanism of Drug Resistance in Clonally Related Clinical Isolates of Vibrio fluvialis Isolated in Kolkata, India
Antimicrob. Agents Chemother. 2006 50: 2428-2432. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

M. Lavollay, K. Mamlouk, T. Frank, A. Akpabie, B. Burghoffer, S. Ben Redjeb, R. Bercion, V. Gautier, and G. Arlet

Clonal Dissemination of a CTX-M-15 ß-Lactamase-Producing Escherichia coli Strain in the Paris Area, Tunis, and Bangui
Antimicrob. Agents Chemother. 2006 50: 2433-2438. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

A. S. Bayer, L. I. Kupferwasser, M. H. Brown, R. A. Skurray, S. Grkovic, T. Jones, K. Mukhopadhay, and M. R. Yeaman

Low-Level Resistance of Staphylococcus aureus to Thrombin-Induced Platelet Microbicidal Protein 1 In Vitro Associated with qacA Gene Carriage Is Independent of Multidrug Efflux Pump Activity
Antimicrob. Agents Chemother. 2006 50: 2448-2454. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Yumiko Sanbongi, Takahisa Suzuki, Yumi Osaki, Nami Senju, Takashi Ida, and Kimiko Ubukata

Molecular Evolution of ß-Lactam-Resistant Haemophilus influenzae: 9-Year Surveillance of Penicillin-Binding Protein 3 Mutations in Isolates from Japan
Antimicrob. Agents Chemother. 2006 50: 2487-2492. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Daniela Ceccarelli, Anna Maria Salvia, Joana Sami, Piero Cappuccinelli, and Mauro Maria Colombo

New Cluster of Plasmid-Located Class 1 Integrons in Vibrio cholerae O1 and a dfrA15 Cassette-Containing Integron in Vibrio parahaemolyticus Isolated in Angola
Antimicrob. Agents Chemother. 2006 50: 2493-2499. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Katherine S. Long, Jacob Poehlsgaard, Corinna Kehrenberg, Stefan Schwarz, and Birte Vester

The Cfr rRNA Methyltransferase Confers Resistance to Phenicols, Lincosamides, Oxazolidinones, Pleuromutilins, and Streptogramin A Antibiotics
Antimicrob. Agents Chemother. 2006 50: 2500-2505. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Julie M. Struble and Ryan T. Gill

Reverse Engineering Antibiotic Sensitivity in a Multidrug-Resistant Pseudomonas aeruginosa Isolate
Antimicrob. Agents Chemother. 2006 50: 2506-2515. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Eric Sauvage, Eveline Fonzé, Birgit Quinting, Moreno Galleni, Jean-Marie Frère, and Paulette Charlier

Crystal Structure of the Mycobacterium fortuitum Class A ß-Lactamase: Structural Basis for Broad Substrate Specificity
Antimicrob. Agents Chemother. 2006 50: 2516-2521. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

E. M. F. Rocha, R. E. Gardiner, S. Park, N. M. Martinez-Rossi, and D. S. Perlin

A Phe389Leu Substitution in ErgA Confers Terbinafine Resistance in Aspergillus fumigatus
Antimicrob. Agents Chemother. 2006 50: 2533-2536. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jose-Manuel Rodriguez-Martinez, Laurent Poirel, Rafael Canton, and Patrice Nordmann

Common Region CR1 for Expression of Antibiotic Resistance Genes
Antimicrob. Agents Chemother. 2006 50: 2544-2546. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Nadya Andini and Kevin A. Nash

Intrinsic Macrolide Resistance of the Mycobacterium tuberculosis Complex Is Inducible
Antimicrob. Agents Chemother. 2006 50: 2560-2562. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hedi Mammeri, Laurent Poirel, Nicolas Fortineau, and Patrice Nordmann

Naturally Occurring Extended-Spectrum Cephalosporinases in Escherichia coli
Antimicrob. Agents Chemother. 2006 50: 2573-2576. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Carla Vignaroli, Francesca Biavasco, and Pietro E. Varaldo

Interactions between Glycopeptides and ß-Lactams against Isogenic Pairs of Teicoplanin-Susceptible and -Resistant Strains of Staphylococcus haemolyticus
Antimicrob. Agents Chemother. 2006 50: 2577-2582. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Antiviral Agents:

Xiao-Jian Zhou, Barbara A. Fielman, Deborah M. Lloyd, George C. Chao, and Nathaniel A. Brown

Pharmacokinetics of Telbivudine in Healthy Subjects and Absence of Drug Interaction with Lamivudine or Adefovir Dipivoxil
Antimicrob. Agents Chemother. 2006 50: 2309-2315. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Chin-chung Lin, Christine Xu, Nanqun Zhu, and Li-Tain Yeh

Absorption, Metabolism, and Excretion of [¹⁴C]Viramidine in Humans
Antimicrob. Agents Chemother. 2006 50: 2368-2373. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Arnold S. Monto, Jennifer L. McKimm-Breschkin, Catherine Macken, Alan W. Hampson, Alan Hay, Alexander Klimov, Masato Tashiro, Robert G. Webster, Michelle Aymard, Frederick G. Hayden, and Maria Zambon

Detection of Influenza Viruses Resistant to Neuraminidase Inhibitors in Global Surveillance during the First 3 Years of Their Use
Antimicrob. Agents Chemother. 2006 50: 2395-2402. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

R. A. Desmond, N. A. Accortt, L. Talley, S. A. Villano, S.-J. Soong, and R. J. Whitley

Enteroviral Meningitis: Natural History and Outcome of Pleconaril Therapy
Antimicrob. Agents Chemother. 2006 50: 2409-2414. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

William E. Delaney, IV, Adrian S. Ray, Huiling Yang, Xiaoping Qi, Shelly Xiong, Yuao Zhu, and Michael D. Miller

Intracellular Metabolism and In Vitro Activity of Tenofovir against Hepatitis B Virus
Antimicrob. Agents Chemother. 2006 50: 2471-2477. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ilya Lebeau, Graciela Andrei, Fabiana Dal Pozzo, James R. Beadle, Karl Y. Hostetler, Erik De Clercq, Joost van den Oord, and Robert Snoeck

Activities of Alkoxyalkyl Esters of Cidofovir (CDV), Cyclic CDV, and (S)-9-(3-Hydroxy-2-Phosphonylmethoxypropyl)Adenine against Orthopoxviruses in Cell Monolayers and in Organotypic Cultures
Antimicrob. Agents Chemother. 2006 50: 2525-2529. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Marc Wirden, Bénédicte Roquebert, Anne Derache, Anne Simon, Claudine Duvivier, Jade Ghosn, Stephanie Dominguez, Véronique Boutonnet, Zaina Ait-Arkoub, Christine Katlama, Vincent Calvez, and Anne-Genevieve Marcelin

Risk Factors for Selection of the L74I Reverse Transcriptase Mutation in Human Immunodeficiency Virus Type 1-Infected Patients
Antimicrob. Agents Chemother. 2006 50: 2553-2556. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sunwen Chou, Laura C. Van Wechel, and Gail I. Marousek

Effect of Cell Culture Conditions on the Anticytomegalovirus Activity of Maribavir
Antimicrob. Agents Chemother. 2006 50: 2557-2559. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Action:

Joanne E. Thwaite, Stephen Hibbs, Richard W. Titball, and Timothy P. Atkins

Proteolytic Degradation of Human Antimicrobial Peptide LL-37 by Bacillus anthracis May Contribute to Virulence
Antimicrob. Agents Chemother. 2006 50: 2316-2322. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Miguel A. Campos, Pau Morey, and José A. Bengoechea

Quinolones Sensitize Gram-Negative Bacteria to Antimicrobial Peptides
Antimicrob. Agents Chemother. 2006 50: 2361-2367. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Coy D. Fitch and Natrice V. Russell

Accelerated Denaturation of Hemoglobin and the Antimalarial Action of Chloroquine
Antimicrob. Agents Chemother. 2006 50: 2415-2419. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Alicia Ponte-Sucre, Radim Vicik, Martina Schultheis, Tanja Schirmeister, and Heidrun Moll

Aziridine-2,3-Dicarboxylates, Peptidomimetic Cysteine Protease Inhibitors with Antileishmanial Activity
Antimicrob. Agents Chemother. 2006 50: 2439-2447. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Experimental Therapeutics:

Melanie T. Cushion, Peter D. Walzer, Alan Ashbaugh, Sandra Rebholz, Ronald Brubaker, Jean Jacques Vanden Eynde, Annie Mayence, and Tien L. Huang

In Vitro Selection and In Vivo Efficacy of Piperazine- and Alkanediamide-Linked Bisbenzamidines against Pneumocystis Pneumonia in Mice
Antimicrob. Agents Chemother. 2006 50: 2337-2343. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

N. McCallum, H. Karauzum, R. Getzmann, M. Bischoff, P. Majcherczyk, B. Berger-Bächi, and R. Landmann

In Vivo Survival of Teicoplanin-Resistant Staphylococcus aureus and Fitness Cost of Teicoplanin Resistance
Antimicrob. Agents Chemother. 2006 50: 2352-2360. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

D. Andes, A. Forrest, A. Lepak, J. Nett, K. Marchillo, and L. Lincoln

Impact of Antimicrobial Dosing Regimen on Evolution of Drug Resistance In Vivo: Fluconazole and Candida albicans
Antimicrob. Agents Chemother. 2006 50: 2374-2383. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

D. Andes, A. Lepak, J. Nett, L. Lincoln, and K. Marchillo

In Vivo Fluconazole Pharmacodynamics and Resistance Development in a Previously Susceptible Candida albicans Population Examined by Microbiologic and Transcriptional Profiling
Antimicrob. Agents Chemother. 2006 50: 2384-2394. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Jun Wang, Hong Zhou, Jiang Zheng, Juan Cheng, Wei Liu, Guofu Ding, Liangxi Wang, Ping Luo, Yongling Lu, Hongwei Cao, Shuangjiang Yu, Bin Li, and Lezhi Zhang

The Antimalarial Artemisinin Synergizes with Antibiotics To Protect against Lethal Live Escherichia coli Challenge by Decreasing Proinflammatory Cytokine Release
Antimicrob. Agents Chemother. 2006 50: 2420-2427. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Andrea Giacometti, Oscar Cirioni, Roberto Ghiselli, Federico Mocchegiani, Fiorenza Orlando, Carmela Silvestri, Argante Bozzi, Antonio Di Giulio, Carla Luzi, Maria Luisa Mangoni, Donatella Barra, Vittorio Saba, Giorgio Scalise, and Andrea C. Rinaldi

Interaction of Antimicrobial Peptide Temporin L with Lipopolysaccharide In Vitro and in Experimental Rat Models of Septic Shock Caused by Gram-Negative Bacteria
Antimicrob. Agents Chemother. 2006 50: 2478-2486. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

David L. Paterson, Usha Stiefel, and Curtis J. Donskey

Effect of a Selective Decontamination of the Digestive Tract Regimen Including Parenteral Cefepime on Establishment of Intestinal Colonization with Vancomycin-Resistant Enterococcus spp. and Klebsiella pneumoniae in Mice
Antimicrob. Agents Chemother. 2006 50: 2537-2540. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Cedric Jacqueline, Jocelyne Caillon, Olivier Grossi, Virginie Le Mabecque, Anne-Françoise Miegeville, Denis Bugnon, Eric Batard, and Gilles Potel

In Vitro and In Vivo Assessment of Linezolid Combined with Ertapenem: a Highly Synergistic Combination against Methicillin-Resistant Staphylococcus aureus
Antimicrob. Agents Chemother. 2006 50: 2547-2549. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

P. Ruggiero, F. Tombola, G. Rossi, L. Pancotto, L. Lauretti, G. Del Giudice, and M. Zoratti

Polyphenols Reduce Gastritis Induced by Helicobacter pylori Infection or VacA Toxin Administration in Mice
Antimicrob. Agents Chemother. 2006 50: 2550-2552. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Anthony Cacciapuoti, Judith Halpern, Cara Mendrick, Christine Norris, Reena Patel, and David Loebenberg

Interaction between Posaconazole and Caspofungin in Concomitant Treatment of Mice with Systemic Aspergillus Infection
Antimicrob. Agents Chemother. 2006 50: 2587-2590. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Errata:

Davina Hiller, Dominique Sanglard, and Joachim Morschhäuser

Overexpression of the MDR1 Gene Is Sufficient To Confer Increased Resistance to Toxic Compounds in Candida albicans
Antimicrob. Agents Chemother. 2006 50: 2591. [Full Text] [PDF] [Reprints and Permissions]  

Lilian Pumbwe, Luke P. Randall, Martin J. Woodward, and Laura J. V. Piddock

Evidence for Multiple-Antibiotic Resistance in Campylobacter jejuni Not Mediated by CmeB or CmeF
Antimicrob. Agents Chemother. 2006 50: 2592. [Full Text] [PDF] [Reprints and Permissions]  

Karl V. Clemons, Marife Espiritu, Rachana Parmar, and David A. Stevens

Assessment of the Paradoxical Effect of Caspofungin in Therapy of Candidiasis
Antimicrob. Agents Chemother. 2006 50: 2593. [Full Text] [PDF] [Reprints and Permissions]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.