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Mechanisms of Action:

Ludovic Gros, Victor Manuel Castillo-Acosta, Carmen Jiménez Jiménez, Marco Sealey-Cardona, Sofia Vargas, Antonio Manuel Estévez, Vanessa Yardley, Lauren Rattray, Simon L. Croft, Luis M. Ruiz-Perez, Julio A. Urbina, Ian H. Gilbert, and Dolores González Pacanowska

New Azasterols against Trypanosoma brucei: Role of 24-Sterol Methyltransferase in Inhibitor Action
Antimicrob. Agents Chemother. 2006 50: 2595-2601. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Daiju Okuda, Shin Yomogida, Hiroshi Tamura, and Isao Nagaoka

Determination of the Antibacterial and Lipopolysaccharide-Neutralizing Regions of Guinea Pig Neutrophil Cathelicidin Peptide CAP11
Antimicrob. Agents Chemother. 2006 50: 2602-2607. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

H. Steffen, S. Rieg, I. Wiedemann, H. Kalbacher, M. Deeg, H.-G. Sahl, A. Peschel, F. Götz, C. Garbe, and B. Schittek

Naturally Processed Dermcidin-Derived Peptides Do Not Permeabilize Bacterial Membranes and Kill Microorganisms Irrespective of Their Charge
Antimicrob. Agents Chemother. 2006 50: 2608-2620. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Vincent H. Tam, Samer Kabbara, Giao Vo, Amy N. Schilling, and Elizabeth A. Coyle

Comparative Pharmacodynamics of Gentamicin against Staphylococcus aureus and Pseudomonas aeruginosa
Antimicrob. Agents Chemother. 2006 50: 2626-2631. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Mahtab Moayeri, Jason F. Wiggins, Robin E. Lindeman, and Stephen H. Leppla

Cisplatin Inhibition of Anthrax Lethal Toxin
Antimicrob. Agents Chemother. 2006 50: 2658-2665. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Shahar Rotem, Inna Radzishevsky, and Amram Mor

Physicochemical Properties That Enhance Discriminative Antibacterial Activity of Short Dermaseptin Derivatives
Antimicrob. Agents Chemother. 2006 50: 2666-2672. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

C. Freiberg, J. Pohlmann, P. G. Nell, R. Endermann, J. Schuhmacher, B. Newton, M. Otteneder, T. Lampe, D. Häbich, and K. Ziegelbauer

Novel Bacterial Acetyl Coenzyme A Carboxylase Inhibitors with Antibiotic Efficacy In Vivo
Antimicrob. Agents Chemother. 2006 50: 2707-2712. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Veronika Simons, John P. Morrissey, Maita Latijnhouwers, Michael Csukai, Adam Cleaver, Carol Yarrow, and Anne Osbourn

Dual Effects of Plant Steroidal Alkaloids on Saccharomyces cerevisiae
Antimicrob. Agents Chemother. 2006 50: 2732-2740. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Lucas D. Tilley, Orion S. Hine, Jill A. Kellogg, Jed N. Hassinger, Dwight D. Weller, Patrick L. Iversen, and Bruce L. Geller

Gene-Specific Effects of Antisense Phosphorodiamidate Morpholino Oligomer-Peptide Conjugates on Escherichia coli and Salmonella enterica Serovar Typhimurium in Pure Culture and in Tissue Culture
Antimicrob. Agents Chemother. 2006 50: 2789-2796. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jingsong Zhu, Paul W. Luther, Qixin Leng, and A. James Mixson

Synthetic Histidine-Rich Peptides Inhibit Candida Species and Other Fungi In Vitro: Role of Endocytosis and Treatment Implications
Antimicrob. Agents Chemother. 2006 50: 2797-2805. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Deborah E. Geiman, Tirumalai R. Raghunand, Nisheeth Agarwal, and William R. Bishai

Differential Gene Expression in Response to Exposure to Antimycobacterial Agents and Other Stress Conditions among Seven Mycobacterium tuberculosis whiB-Like Genes
Antimicrob. Agents Chemother. 2006 50: 2836-2841. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sho Takahata, Maiko Iida, Yumi Osaki, Jun Saito, Hideo Kitagawa, Tomohiro Ozawa, Takuji Yoshida, and Shigeru Hoshiko

AG205, a Novel Agent Directed against FabK of Streptococcus pneumoniae
Antimicrob. Agents Chemother. 2006 50: 2869-2871. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Experimental Therapeutics:

Eric Nuermberger, Ian Rosenthal, Sandeep Tyagi, Kathy N. Williams, Deepak Almeida, Charles A. Peloquin, William R. Bishai, and Jacques H. Grosset

Combination Chemotherapy with the Nitroimidazopyran PA-824 and First-Line Drugs in a Murine Model of Tuberculosis
Antimicrob. Agents Chemother. 2006 50: 2621-2625. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Karl V. Clemons, Gloria M. Gonzalez, Gaurav Singh, Jackie Imai, Marife Espiritu, Rachana Parmar, and David A. Stevens

Development of an Orogastrointestinal Mucosal Model of Candidiasis with Dissemination to Visceral Organs
Antimicrob. Agents Chemother. 2006 50: 2650-2657. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Francesco Barchiesi, Elisabetta Spreghini, Serena Tomassetti, Agnese Della Vittoria, Daniela Arzeni, Esther Manso, and Giorgio Scalise

Effects of Caspofungin against Candida guilliermondii and Candida parapsilosis
Antimicrob. Agents Chemother. 2006 50: 2719-2727. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Salman Baig, Raymond T. Damian, Jorge Morales-Montor, Rupal Thazhath, Amr Ghaleb, Meredith Welch, Jamil Talhouk, and A. Clinton White, Jr.

Cysteine Proteinase Inhibitors in Murine Cysticercosis
Antimicrob. Agents Chemother. 2006 50: 2886-2888. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Resistance:

Katarzyna A. Kazimierczak, Harry J. Flint, and Karen P. Scott

Comparative Analysis of Sequences Flanking tet(W) Resistance Genes in Multiple Species of Gut Bacteria
Antimicrob. Agents Chemother. 2006 50: 2632-2639. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Manzour Hernando Hazbón, Michael Brimacombe, Miriam Bobadilla del Valle, Magali Cavatore, Marta Inírida Guerrero, Mandira Varma-Basil, Helen Billman-Jacobe, Caroline Lavender, Janet Fyfe, Lourdes García-García, Clara Inés León, Mridula Bose, Fernando Chaves, Megan Murray, Kathleen D. Eisenach, José Sifuentes-Osornio, M. Donald Cave, Alfredo Ponce de León, and David Alland

Population Genetics Study of Isoniazid Resistance Mutations and Evolution of Multidrug-Resistant Mycobacterium tuberculosis
Antimicrob. Agents Chemother. 2006 50: 2640-2649. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Christine Voha, Jean-Denis Docquier, Gian Maria Rossolini, and Thierry Fosse

Genetic and Biochemical Characterization of FUS-1 (OXA-85), a Narrow-Spectrum Class D ß-Lactamase from Fusobacterium nucleatum subsp. polymorphum
Antimicrob. Agents Chemother. 2006 50: 2673-2679. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Claudia Mugnaioli, Francesco Luzzaro, Filomena De Luca, Gioconda Brigante, Mariagrazia Perilli, Gianfranco Amicosante, Stefania Stefani, Antonio Toniolo, and Gian Maria Rossolini

CTX-M-Type Extended-Spectrum ß-Lactamases in Italy: Molecular Epidemiology of an Emerging Countrywide Problem
Antimicrob. Agents Chemother. 2006 50: 2700-2706. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ângela Novais, Rafael Cantón, Aránzazu Valverde, Elisabete Machado, Juan-Carlos Galán, Luísa Peixe, Alessandra Carattoli, Fernando Baquero, and Teresa M. Coque

Dissemination and Persistence of bla_CTX-M-9 Are Linked to Class 1 Integrons Containing CR1 Associated with Defective Transposon Derivatives from Tn402 Located in Early Antibiotic Resistance Plasmids of IncHI2, IncP1-, and IncFI Groups
Antimicrob. Agents Chemother. 2006 50: 2741-2750. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Feng Wang, Craig Cassidy, and James C. Sacchettini

Crystal Structure and Activity Studies of the Mycobacterium tuberculosis ß-Lactamase Reveal Its Critical Role in Resistance to ß-Lactam Antibiotics
Antimicrob. Agents Chemother. 2006 50: 2762-2771. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Michael J. Noto and Gordon L. Archer

A Subset of Staphylococcus aureus Strains Harboring Staphylococcal Cassette Chromosome mec (SCCmec) Type IV Is Deficient in CcrAB-Mediated SCCmec Excision
Antimicrob. Agents Chemother. 2006 50: 2782-2788. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Igor Mokrousov, Wei Wei Jiao, Gui Zhi Sun, Jia Wen Liu, Violeta Valcheva, Mo Li, Olga Narvskaya, and A Dong Shen

Evolution of Drug Resistance in Different Sublineages of Mycobacterium tuberculosis Beijing Genotype
Antimicrob. Agents Chemother. 2006 50: 2820-2823. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Caitriona M. Guinane, Paul D. Cotter, R. Paul Ross, and Colin Hill

Contribution of Penicillin-Binding Protein Homologs to Antibiotic Resistance, Cell Morphology, and Virulence of Listeria monocytogenes EGDe
Antimicrob. Agents Chemother. 2006 50: 2824-2828. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Dóra Szabó, Fernanda Silveira, Andrea M. Hujer, Robert A. Bonomo, Kristine M. Hujer, Jane W. Marsh, Christopher R. Bethel, Yohei Doi, Kathleen Deeley, and David L. Paterson

Outer Membrane Protein Changes and Efflux Pump Expression Together May Confer Resistance to Ertapenem in Enterobacter cloacae
Antimicrob. Agents Chemother. 2006 50: 2833-2835. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Stephanie Petrella, Emmanuelle Cambau, Aurelie Chauffour, Koen Andries, Vincent Jarlier, and Wladimir Sougakoff

Genetic Basis for Natural and Acquired Resistance to the Diarylquinoline R207910 in Mycobacteria
Antimicrob. Agents Chemother. 2006 50: 2853-2856. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Emma Huitric, Jim Werngren, Pontus Juréen, and Sven Hoffner

Resistance Levels and rpoB Gene Mutations among In Vitro-Selected Rifampin-Resistant Mycobacterium tuberculosis Mutants
Antimicrob. Agents Chemother. 2006 50: 2860-2862. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Renee S. Levings, Diane Lightfoot, Liam D. H. Elbourne, Steven P. Djordjevic, and Ruth M. Hall

New Integron-Associated Gene Cassette Encoding a Trimethoprim-Resistant DfrB-Type Dihydrofolate Reductase
Antimicrob. Agents Chemother. 2006 50: 2863-2865. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

D. Ready, J. Pratten, A. P. Roberts, R. Bedi, P. Mullany, and M. Wilson

Potential Role of Veillonella spp. as a Reservoir of Transferable Tetracycline Resistance in the Oral Cavity
Antimicrob. Agents Chemother. 2006 50: 2866-2868. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

A. Robicsek, J. Strahilevitz, D. F. Sahm, G. A. Jacoby, and D. C. Hooper

qnr Prevalence in Ceftazidime-Resistant Enterobacteriaceae Isolates from the United States
Antimicrob. Agents Chemother. 2006 50: 2872-2874. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Maria Virginia Villegas, Karen Lolans, Adriana Correa, Carlos Jose Suarez, Jaime A. Lopez, Marta Vallejo, John P. Quinn the Colombian Nosocomial Resistance Study Group

First Detection of the Plasmid-Mediated Class A Carbapenemase KPC-2 in Clinical Isolates of Klebsiella pneumoniae from South America
Antimicrob. Agents Chemother. 2006 50: 2880-2882. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Laurent Poirel, Ludovic Cabanne, Louis Collet, and Patrice Nordmann

Class II Transposon-Borne Structure Harboring Metallo-ß-Lactamase Gene bla_VIM-2 in Pseudomonas putida
Antimicrob. Agents Chemother. 2006 50: 2889-2891. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Santosh Katiyar, Michael Pfaller, and Thomas Edlind

Candida albicans and Candida glabrata Clinical Isolates Exhibiting Reduced Echinocandin Susceptibility
Antimicrob. Agents Chemother. 2006 50: 2892-2894. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Susceptibility:

Olivier Denis, Ariane Deplano, Claire Nonhoff, Marie Hallin, Raf De Ryck, Raymond Vanhoof, Ricardo De Mendonça, and Marc J. Struelens

In Vitro Activities of Ceftobiprole, Tigecycline, Daptomycin, and 19 Other Antimicrobials against Methicillin-Resistant Staphylococcus aureus Strains from a National Survey of Belgian Hospitals
Antimicrob. Agents Chemother. 2006 50: 2680-2685. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

María-Isabel Morosini, María García-Castillo, Teresa M. Coque, Aránzazu Valverde, Ângela Novais, Elena Loza, Fernando Baquero, and Rafael Cantón

Antibiotic Coresistance in Extended-Spectrum-ß-Lactamase-Producing Enterobacteriaceae and In Vitro Activity of Tigecycline
Antimicrob. Agents Chemother. 2006 50: 2695-2699. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kerin L. Tyrrell, Diane M. Citron, Yumi A. Warren, Helen T. Fernandez, C. Vreni Merriam, and Ellie J. C. Goldstein

In Vitro Activities of Daptomycin, Vancomycin, and Penicillin against Clostridium difficile, C. perfringens, Finegoldia magna, and Propionibacterium acnes
Antimicrob. Agents Chemother. 2006 50: 2728-2731. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Emilia Cantón, Javier Pemán, Macrina Sastre, Mónica Romero, and Ana Espinel-Ingroff

Killing Kinetics of Caspofungin, Micafungin, and Amphotericin B against Candida guilliermondii
Antimicrob. Agents Chemother. 2006 50: 2829-2832. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Muhammad Malik and Karl Drlica

Moxifloxacin Lethality against Mycobacterium tuberculosis in the Presence and Absence of Chloramphenicol
Antimicrob. Agents Chemother. 2006 50: 2842-2844. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Patricia Assunção, Nuno T. Antunes, Ruben S. Rosales, Carlos Poveda, Jose B. Poveda, and Hazel M. Davey

Flow Cytometric Determination of the Effects of Antibacterial Agents on Mycoplasma agalactiae, Mycoplasma putrefaciens, Mycoplasma capricolum subsp. capricolum, and Mycoplasma mycoides subsp. mycoides Large Colony Type
Antimicrob. Agents Chemother. 2006 50: 2845-2849. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Yvonne Adams, Craig Freeman, Reinhard Schwartz-Albiez, Vito Ferro, Christopher R. Parish, and Katherine T. Andrews

Inhibition of Plasmodium falciparum Growth In Vitro and Adhesion to Chondroitin-4-Sulfate by the Heparan Sulfate Mimetic PI-88 and Other Sulfated Oligosaccharides
Antimicrob. Agents Chemother. 2006 50: 2850-2852. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ellie J. C. Goldstein, Diane M. Citron, Yumi A. Warren, Kerin L. Tyrrell, C. Vreni Merriam, and Helen T. Fernandez

In Vitro Activities of Dalbavancin and 12 Other Agents against 329 Aerobic and Anaerobic Gram-Positive Isolates Recovered from Diabetic Foot Infections
Antimicrob. Agents Chemother. 2006 50: 2875-2879. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Timothy M. E. Davis, Juliana Hamzah, Kenneth F. Ilett, Harin A. Karunajeewa, John C. Reeder, Kevin T. Batty, Sara Hackett, and P. Hugh R. Barrett

In Vitro Interactions between Piperaquine, Dihydroartemisinin, and Other Conventional and Novel Antimalarial Drugs
Antimicrob. Agents Chemother. 2006 50: 2883-2885. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Antiviral Agents:

Zexun Zhou, John H. Rodman, Patricia M. Flynn, Brian L. Robbins, Carrie K. Wilcox, and David Z. D'Argenio

Model for Intracellular Lamivudine Metabolism in Peripheral Blood Mononuclear Cells Ex Vivo and in Human Immunodeficiency Virus Type 1-Infected Adolescents
Antimicrob. Agents Chemother. 2006 50: 2686-2694. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Amanda H. Corbett, Kristine B. Patterson, Hsiao-Chuan Tien, Leslie A. Kalvass, Joseph J. Eron, Linh T. Ngo, Michael L. Lim, and Angela D. M. Kashuba

Dose Separation Does Not Overcome the Pharmacokinetic Interaction between Fosamprenavir and Lopinavir/Ritonavir
Antimicrob. Agents Chemother. 2006 50: 2756-2761. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Zhijun Zhang, Michelle Walker, Wen Xu, Jae Hoon Shim, Jean-Luc Girardet, Robert K. Hamatake, and Zhi Hong

Novel Nonnucleoside Inhibitors That Select Nucleoside Inhibitor Resistance Mutations in Human Immunodeficiency Virus Type 1 Reverse Transcriptase
Antimicrob. Agents Chemother. 2006 50: 2772-2781. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

T. Ueno, Y. Eizuru, H. Katano, T. Kurata, T. Sata, S. Irie, and K. Ogawa-Goto

Novel Real-Time Monitoring System for Human Cytomegalovirus- Infected Cells In Vitro That Uses a Green Fluorescent Protein-PML-Expressing Cell Line
Antimicrob. Agents Chemother. 2006 50: 2806-2813. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Karl Y. Hostetler, Kathy A. Aldern, William B. Wan, Stephanie L. Ciesla, and James R. Beadle

Alkoxyalkyl Esters of (S)-9-[3-Hydroxy-2-(Phosphonomethoxy)Propyl]Adenine Are Potent Inhibitors of the Replication of Wild-Type and Drug-Resistant Human Immunodeficiency Virus Type 1 In Vitro
Antimicrob. Agents Chemother. 2006 50: 2857-2859. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Clinical Therapeutics:

Steffen Borrmann, Ingrid Lundgren, Sunny Oyakhirome, Bénido Impouma, Pierre-Blaise Matsiegui, Ayola A. Adegnika, Saadou Issifou, Jürgen F. J. Kun, David Hutchinson, Jochen Wiesner, Hassan Jomaa, and Peter G. Kremsner

Fosmidomycin plus Clindamycin for Treatment of Pediatric Patients Aged 1 to 14 Years with Plasmodium falciparum Malaria
Antimicrob. Agents Chemother. 2006 50: 2713-2718. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

J. John Weems, Jr., James P. Steinberg, Scott Filler, John W. Baddley, G. Ralph Corey, Priya Sampathkumar, Lisa Winston, Joseph F. John, Christine J. Kubin, Rohit Talwani, Thomas Moore, Joseph M. Patti, Seth Hetherington, Michele Texter, Eric Wenzel, Violet A. Kelley, and Vance G. Fowler, Jr.

Phase II, Randomized, Double-Blind, Multicenter Study Comparing the Safety and Pharmacokinetics of Tefibazumab to Placebo for Treatment of Staphylococcus aureus Bacteremia
Antimicrob. Agents Chemother. 2006 50: 2751-2755. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Biologic Response Modifiers:

A. F. Marques, M. B. da Silva, M. A. P. Juliano, L. R. Travassos, and C. P. Taborda

Peptide Immunization as an Adjuvant to Chemotherapy in Mice Challenged Intratracheally with Virulent Yeast Cells of Paracoccidioides brasiliensis
Antimicrob. Agents Chemother. 2006 50: 2814-2819. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Letters:

Gunter Rieg, Brad Spellberg, Julie Schwartz, Yue Fu, John E. Edwards, Jr., Donald C. Sheppard, and Ashraf S. Ibrahim

Antifungal Prophylaxis Is Effective against Murine Invasive Pulmonary Aspergillosis
Antimicrob. Agents Chemother. 2006 50: 2895-2896. [Full Text] [PDF] [Reprints and Permissions]  

Takashi Sugita, Mami Tajima, Hisae Tsubuku, Ryoji Tsuboi, and Akemi Nishikawa

A New Calcineurin Inhibitor, Pimecrolimus, Inhibits the Growth of Malassezia spp.
Antimicrob. Agents Chemother. 2006 50: 2897-2898. [Full Text] [PDF] [Reprints and Permissions]  

Henri Benech, François Becher, Alain Pruvost, Jacques J. Grassi, Margarita Meléndez, and José F. Rodriguez

Is Stavudine Triphosphate a Natural Metabolite of Zidovudine?
Antimicrob. Agents Chemother. 2006 50: 2899-2901. [Full Text] [PDF] [Reprints and Permissions]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.