AAC -- Table of Contents (March 1 2007, 51 [3])

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Contents: March 2007, Volume 51, Issue 3

       Mechanisms of Action

       Clinical Therapeutics

       Susceptibility

       Antiviral Agents

       Mechanisms of Resistance

       Pharmacology

       Experimental Therapeutics

       Chemistry; Biosynthesis

       Biologic Response Modifiers

       Letters

       Errata

Other Issues

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Mechanisms of Action:

Inhibition of Gene Expression and Growth by Antisense Peptide Nucleic Acids in a Multiresistant ß-Lactamase-Producing Klebsiella pneumoniae Strain
Prathiba Kurupati, Kevin Shyong Wei Tan, Gamini Kumarasinghe, and Chit Laa Poh
Antimicrob. Agents Chemother. March 2007 51: 805-811; published ahead of print December 11, 2006, doi:10.1128/AAC.00709-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Synthesis of Omeprazole Analogues and Evaluation of These as Potential Inhibitors of the Multidrug Efflux Pump NorA of Staphylococcus aureus
Céline Vidaillac, Jean Guillon, Corinne Arpin, Isabelle Forfar-Bares, Boubakar B. Ba, Jean Grellet, Stéphane Moreau, Daniel-Henri Caignard, Christian Jarry, and Claudine Quentin
Antimicrob. Agents Chemother. March 2007 51: 831-838; published ahead of print November 13, 2006, doi:10.1128/AAC.01306-05
[Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]

Antiparasitic Drug Nitazoxanide Inhibits the Pyruvate Oxidoreductases of Helicobacter pylori, Selected Anaerobic Bacteria and Parasites, and Campylobacter jejuni
Paul S. Hoffman, Gary Sisson, Matthew A. Croxen, Kevin Welch, W. Dean Harman, Nunilo Cremades, and Michael G. Morash
Antimicrob. Agents Chemother. March 2007 51: 868-876; published ahead of print December 11, 2006, doi:10.1128/AAC.01159-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Concentration-Dependent Effects of Caspofungin on the Metabolic Activity of Aspergillus Species
Charalampos Antachopoulos, Joseph Meletiadis, Tin Sein, Emmanuel Roilides, and Thomas J. Walsh
Antimicrob. Agents Chemother. March 2007 51: 881-887; published ahead of print December 4, 2006, doi:10.1128/AAC.01160-06
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In Vitro Effects of Antimicrobial Agents on Planktonic and Biofilm Forms of Staphylococcus lugdunensis Clinical Isolates
Kristi L. Frank, Emily J. Reichert, Kerryl E. Piper, and Robin Patel
Antimicrob. Agents Chemother. March 2007 51: 888-895; published ahead of print December 11, 2006, doi:10.1128/AAC.01052-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Expression of Immunomodulatory Genes in Human Monocytes Induced by Voriconazole in the Presence of Aspergillus fumigatus
M. Simitsopoulou, E. Roilides, C. Likartsis, J. Ioannidis, A. Orfanou, F. Paliogianni, and T. J. Walsh
Antimicrob. Agents Chemother. March 2007 51: 1048-1054; published ahead of print December 18, 2006, doi:10.1128/AAC.01095-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

EthA, a Common Activator of Thiocarbamide-Containing Drugs Acting on Different Mycobacterial Targets
Lynn G. Dover, Anuradha Alahari, Paul Gratraud, Jessica M. Gomes, Veemal Bhowruth, Robert C. Reynolds, Gurdyal S. Besra, and Laurent Kremer
Antimicrob. Agents Chemother. March 2007 51: 1055-1063; published ahead of print January 12, 2007, doi:10.1128/AAC.01063-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Inhibition of Plasmodium falciparum Oocyst Production by Membrane-Permeant Cysteine Protease Inhibitor E64d
S. Eksi, B. Czesny, G.-J. van Gemert, R. W. Sauerwein, W. Eling, and K. C. Williamson
Antimicrob. Agents Chemother. March 2007 51: 1064-1070; published ahead of print December 18, 2006, doi:10.1128/AAC.01012-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Quinoline Derivative MC1626, a Putative GCN5 Histone Acetyltransferase (HAT) Inhibitor, Exhibits HAT-Independent Activity against Toxoplasma gondii
Aaron T. Smith, Meredith R. Livingston, Antonello Mai, Patrizia Filetici, Sherry F. Queener, and William J. Sullivan, Jr.
Antimicrob. Agents Chemother. March 2007 51: 1109-1111; published ahead of print December 18, 2006, doi:10.1128/AAC.01256-06
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Effects of Glutathione and Ascorbic Acid on Streptomycin Sensitivity of Escherichia coli
Manish Goswami, Suhas H. Mangoli, and Narendra Jawali
Antimicrob. Agents Chemother. March 2007 51: 1119-1122; published ahead of print January 8, 2007, doi:10.1128/AAC.00779-06
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Clinical Therapeutics:

Posaconazole Plasma Concentrations in Juvenile Patients with Invasive Fungal Infection
Gopal Krishna, Angela Sansone-Parsons, Monika Martinho, Bhavna Kantesaria, and Lisa Pedicone
Antimicrob. Agents Chemother. March 2007 51: 812-818; published ahead of print January 8, 2007, doi:10.1128/AAC.00454-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Randomized Controlled Comparison of Ofloxacin, Azithromycin, and an Ofloxacin-Azithromycin Combination for Treatment of Multidrug-Resistant and Nalidixic Acid-Resistant Typhoid Fever
Christopher M. Parry, Vo Anh Ho, Le Thi Phuong, Phan Van Be Bay, Mai Ngoc Lanh, Le Thanh Tung, Nguyen Thi Hong Tham, John Wain, Tran Tinh Hien, and Jeremy J. Farrar
Antimicrob. Agents Chemother. March 2007 51: 819-825; published ahead of print December 4, 2006, doi:10.1128/AAC.00447-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Impact of Empiric Antibiotic Therapy on Outcomes in Patients with Pseudomonas aeruginosa Bacteremia
Regina B. Osih, Jessina C. McGregor, Shayna E. Rich, Anita C. Moore, Jon P. Furuno, Eli N. Perencevich, and Anthony D. Harris
Antimicrob. Agents Chemother. March 2007 51: 839-844; published ahead of print December 28, 2006, doi:10.1128/AAC.00901-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Appropriateness of Antimicrobial Therapy Measured by Repeated Prevalence Surveys
Ina Willemsen, Anneke Groenhuijzen, Diana Bogaers, Arie Stuurman, Peter van Keulen, and Jan Kluytmans
Antimicrob. Agents Chemother. March 2007 51: 864-867; published ahead of print January 8, 2007, doi:10.1128/AAC.00994-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Oral versus Intravenous Flucytosine in Patients with Human Immunodeficiency Virus-Associated Cryptococcal Meningitis
Annemarie E. Brouwer, Hendrikus J. M. van Kan, Elizabeth Johnson, Adul Rajanuwong, Prapit Teparrukkul, Vannaporn Wuthiekanun, Wirongrong Chierakul, Nick Day, and Thomas S. Harrison
Antimicrob. Agents Chemother. March 2007 51: 1038-1042; published ahead of print December 28, 2006, doi:10.1128/AAC.01188-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Susceptibility:

In Vitro and In Vivo Activities of a New Cephalosporin, FR264205, against Pseudomonas aeruginosa
Shinobu Takeda, Toru Nakai, Yoshimi Wakai, Fumiaki Ikeda, and Kazuo Hatano
Antimicrob. Agents Chemother. March 2007 51: 826-830; published ahead of print December 4, 2006, doi:10.1128/AAC.00860-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

The ß-Defensin Gallinacin-6 Is Expressed in the Chicken Digestive Tract and Has Antimicrobial Activity against Food-Borne Pathogens
Albert van Dijk, Edwin J. A. Veldhuizen, Stefanie I. C. Kalkhove, Johanna L. M. Tjeerdsma-van Bokhoven, Roland A. Romijn, and Henk P. Haagsman
Antimicrob. Agents Chemother. March 2007 51: 912-922; published ahead of print December 28, 2006, doi:10.1128/AAC.00568-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antimicrobial Susceptibility and Synergy Studies of Burkholderia cepacia Complex Isolated from Patients with Cystic Fibrosis
Juyan Zhou, Yunhua Chen, Setareh Tabibi, Luis Alba, Elizabeth Garber, and Lisa Saiman
Antimicrob. Agents Chemother. March 2007 51: 1085-1088; published ahead of print December 11, 2006, doi:10.1128/AAC.00954-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activities of Tigecycline and Eight Other Antimicrobials against Different Nocardia Species Identified by Molecular Methods
Emilia Cercenado, Mercedes Marín, Mónica Sánchez-Martínez, Oscar Cuevas, José Martínez-Alarcón, and Emilio Bouza
Antimicrob. Agents Chemother. March 2007 51: 1102-1104; published ahead of print December 28, 2006, doi:10.1128/AAC.01102-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activities of Cloxyquin (5-Chloroquinolin-8-ol) against Mycobacterium tuberculosis
Poonpilas Hongmanee, Kamolchanok Rukseree, Benjamas Buabut, Boontiwa Somsri, and Prasit Palittapongarnpim
Antimicrob. Agents Chemother. March 2007 51: 1105-1106; published ahead of print December 18, 2006, doi:10.1128/AAC.01310-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activity of the Oxazolidinone RWJ-416457 against Linezolid-Resistant and -Susceptible Staphylococci and Enterococci
David M. Livermore, Marina Warner, Shazad Mushtaq, Sarah North, and Neil Woodford
Antimicrob. Agents Chemother. March 2007 51: 1112-1114; published ahead of print January 8, 2007, doi:10.1128/AAC.01347-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activities of Amphotericin B, Caspofungin, Itraconazole, Posaconazole, and Voriconazole against 45 Clinical Isolates of Zygomycetes: Comparison of CLSI M38-A, Sensititre YeastOne, and the Etest
Marta Torres-Narbona, Jesús Guinea, José Martínez-Alarcón, Teresa Peláez, and Emilio Bouza
Antimicrob. Agents Chemother. March 2007 51: 1126-1129; published ahead of print December 28, 2006, doi:10.1128/AAC.01539-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antiviral Agents:

Efficacy of Orally Administered T-705 on Lethal Avian Influenza A (H5N1) Virus Infections in Mice
Robert W. Sidwell, Dale L. Barnard, Craig W. Day, Donald F. Smee, Kevin W. Bailey, Min-Hui Wong, John D. Morrey, and Yousuke Furuta
Antimicrob. Agents Chemother. March 2007 51: 845-851; published ahead of print December 28, 2006, doi:10.1128/AAC.01051-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Impact of Nevirapine (NVP) Plasma Concentration on Selection of Resistant Virus in Mothers Who Received Single-Dose NVP To Prevent Perinatal Human Immunodeficiency Virus Type 1 Transmission and Persistence of Resistant Virus in Their Infected Children
Marie-Laure Chaix, Didier Koumavi Ekouevi, Gilles Peytavin, François Rouet, Besigin Tonwe-Gold, Ida Viho, Laurence Bequet, Clarisse Amani-Bosse, Hervé Menan, Valériane Leroy, Christine Rouzioux, François Dabis for the Ditrame Plus ANRS 1201/1202 Study Group
Antimicrob. Agents Chemother. March 2007 51: 896-901; published ahead of print December 18, 2006, doi:10.1128/AAC.00910-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Two-Year Assessment of Entecavir Resistance in Lamivudine-Refractory Hepatitis B Virus Patients Reveals Different Clinical Outcomes Depending on the Resistance Substitutions Present
Daniel J. Tenney, Ronald E. Rose, Carl J. Baldick, Steven M. Levine, Kevin A. Pokornowski, Ann W. Walsh, Jie Fang, Cheng-Fang Yu, Sharon Zhang, Charles E. Mazzucco, Betsy Eggers, Mayla Hsu, Mary Jane Plym, Patricia Poundstone, Joanna Yang, and Richard J. Colonno
Antimicrob. Agents Chemother. March 2007 51: 902-911; published ahead of print December 18, 2006, doi:10.1128/AAC.00833-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mechanisms of Resistance:

Coproduction of Novel 16S rRNA Methylase RmtD and Metallo-ß-Lactamase SPM-1 in a Panresistant Pseudomonas aeruginosa Isolate from Brazil
Yohei Doi, Doroti de Oliveira Garcia, Jennifer Adams, and David L. Paterson
Antimicrob. Agents Chemother. March 2007 51: 852-856; published ahead of print December 11, 2006, doi:10.1128/AAC.01345-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Similar Trends of Pyrimethamine Resistance-Associated Mutations in Plasmodium vivax and P. falciparum
Mohammad Tauqeer Alam, Hema Bora, Praveen K. Bharti, Muheet A. Saifi, Manoj K. Das, Vas Dev, Ashwani Kumar, Neeru Singh, Aditya P. Dash, Brahmananda Das, Wajihullah, and Yagya D. Sharma
Antimicrob. Agents Chemother. March 2007 51: 857-863; published ahead of print December 28, 2006, doi:10.1128/AAC.01200-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Substrate Competition Studies Using Whole-Cell Accumulation Assays with the Major Tripartite Multidrug Efflux Pumps of Escherichia coli
Christopher A. Elkins and Lisa B. Mullis
Antimicrob. Agents Chemother. March 2007 51: 923-929; published ahead of print January 8, 2007, doi:10.1128/AAC.01048-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Flavonoid Dimers as Bivalent Modulators for Pentamidine and Sodium Stiboglucanate Resistance in Leishmania
Iris L. K. Wong, Kin-Fai Chan, Brendan A. Burkett, Yunzhe Zhao, Yi Chai, Hongzhe Sun, Tak Hang Chan, and Larry M. C. Chow
Antimicrob. Agents Chemother. March 2007 51: 930-940; published ahead of print December 28, 2006, doi:10.1128/AAC.00998-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Reduced Susceptibility to Polyenes Associated with a Missense Mutation in the ERG6 Gene in a Clinical Isolate of Candida glabrata with Pseudohyphal Growth
Patrick Vandeputte, Guy Tronchin, Thierry Bergès, Christophe Hennequin, Dominique Chabasse, and Jean-Philippe Bouchara
Antimicrob. Agents Chemother. March 2007 51: 982-990; published ahead of print December 11, 2006, doi:10.1128/AAC.01510-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Amodiaquine and Artemether-Lumefantrine Select Distinct Alleles of the Plasmodium falciparum mdr1 Gene in Tanzanian Children Treated for Uncomplicated Malaria
G. S. Humphreys, I. Merinopoulos, J. Ahmed, C. J. M. Whitty, T. K. Mutabingwa, C. J. Sutherland, and R. L. Hallett
Antimicrob. Agents Chemother. March 2007 51: 991-997; published ahead of print December 28, 2006, doi:10.1128/AAC.00875-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Reduced Susceptibility of Haemophilus influenzae to the Peptide Deformylase Inhibitor LBM415 Can Result from Target Protein Overexpression Due to Amplified Chromosomal def Gene Copy Number
Charles R. Dean, Shubha Narayan, Joel Richards, Denis M. Daigle, Stacy Esterow, Jennifer A. Leeds, Heather Kamp, Xiaoling Puyang, Brigitte Wiedmann, Dieter Mueller, Hans Voshol, Jan van Oostrum, Daniel Wall, James Koehn, JoAnn Dzink-Fox, and Neil S. Ryder
Antimicrob. Agents Chemother. March 2007 51: 1004-1010; published ahead of print January 12, 2007, doi:10.1128/AAC.01103-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Cumulative Effects of Several Nonenzymatic Mechanisms on the Resistance of Pseudomonas aeruginosa to Aminoglycosides
Farid El'Garch, Katy Jeannot, Didier Hocquet, Catherine Llanes-Barakat, and Patrick Plésiat
Antimicrob. Agents Chemother. March 2007 51: 1016-1021; published ahead of print December 28, 2006, doi:10.1128/AAC.00704-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Independent Evolution of Pyrimethamine Resistance in Plasmodium falciparum Isolates in Melanesia
Toshihiro Mita, Kazuyuki Tanabe, Nobuyuki Takahashi, Takahiro Tsukahara, Hideaki Eto, Lek Dysoley, Hiroshi Ohmae, Kiyoshi Kita, Srivicha Krudsood, Sornchai Looareesuwan, Akira Kaneko, Anders Björkman, and Takatoshi Kobayakawa
Antimicrob. Agents Chemother. March 2007 51: 1071-1077; published ahead of print January 8, 2007, doi:10.1128/AAC.01186-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Detection of a New SHV-Type Extended-Spectrum ß-Lactamase, SHV-31, in a Klebsiella pneumoniae Strain Causing a Large Nosocomial Outbreak in The Netherlands
A. Mazzariol, E. Roelofsen, R. Koncan, A. Voss, and G. Cornaglia
Antimicrob. Agents Chemother. March 2007 51: 1082-1084; published ahead of print December 18, 2006, doi:10.1128/AAC.00909-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Evaluation of Accessory Gene Regulator (agr) Group and Function in the Proclivity towards Vancomycin Intermediate Resistance in Staphylococcus aureus
Brian T. Tsuji, Michael J. Rybak, Kerry L. Lau, and George Sakoulas
Antimicrob. Agents Chemother. March 2007 51: 1089-1091; published ahead of print December 11, 2006, doi:10.1128/AAC.00671-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

High-Level Telithromycin Resistance in a Clinical Isolate of Streptococcus pneumoniae
Nicole Wolter, Anthony M. Smith, Donald E. Low, and Keith P. Klugman
Antimicrob. Agents Chemother. March 2007 51: 1092-1095; published ahead of print January 8, 2007, doi:10.1128/AAC.01153-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Assessment of the Effect of Mefloquine on Artesunate Pharmacokinetics in Healthy Male Volunteers
Timothy M. E. Davis, Michelle England, Anne-Marie Dunlop, Madhu Page-Sharp, Nathalie Cambon, Thomas G. Keller, János L. Heidecker, and Kenneth F. Ilett
Antimicrob. Agents Chemother. March 2007 51: 1099-1101; published ahead of print December 18, 2006, doi:10.1128/AAC.01253-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mosaic Tetracycline Resistance Genes Are Widespread in Human and Animal Fecal Samples
Andrea J. Patterson, Marco T. Rincon, Harry J. Flint, and Karen P. Scott
Antimicrob. Agents Chemother. March 2007 51: 1115-1118; published ahead of print December 18, 2006, doi:10.1128/AAC.00725-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antibiotic Resistance of Campylobacter jejuni and Campylobacter coli Clinical Isolates from Poland
Sebastian Wardak, Jolanta Szych, Aleksandra Anna Zasada, and Rafal Gierczynski
Antimicrob. Agents Chemother. March 2007 51: 1123-1125; published ahead of print January 8, 2007, doi:10.1128/AAC.01187-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pharmacology:

Comparative Pharmacokinetics of Voriconazole Administered Orally as either Crushed or Whole Tablets
E. S. Dodds Ashley, A. K. Zaas, A. F. Fang, B. Damle, and J. R. Perfect
Antimicrob. Agents Chemother. March 2007 51: 877-880; published ahead of print December 4, 2006, doi:10.1128/AAC.01263-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pharmacokinetic Interaction between Darunavir Boosted with Ritonavir and Omeprazole or Ranitidine in Human Immunodeficiency Virus-Negative Healthy Volunteers
Vanitha J. Sekar, Eric Lefebvre, Els De Paepe, Tine De Marez, Martine De Pauw, Wim Parys, and Richard M. W. Hoetelmans
Antimicrob. Agents Chemother. March 2007 51: 958-961; published ahead of print January 8, 2007, doi:10.1128/AAC.01203-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Reversible Inhibition of Mitochondrial Protein Synthesis during Linezolid-Related Hyperlactatemia
Glòria Garrabou, Alejandro Soriano, Sònia López, Jordi P. Guallar, Marta Giralt, Francesc Villarroya, Jose A. Martínez, Jordi Casademont, Francesc Cardellach, Josep Mensa, and Òscar Miró
Antimicrob. Agents Chemother. March 2007 51: 962-967; published ahead of print December 28, 2006, doi:10.1128/AAC.01190-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Diminished Ciprofloxacin-Induced Chondrotoxicity by Supplementation with Magnesium and Vitamin E in Immature Rats
Kerstin Pfister, Dago Mazur, Jürgen Vormann, and Ralf Stahlmann
Antimicrob. Agents Chemother. March 2007 51: 1022-1027; published ahead of print January 8, 2007, doi:10.1128/AAC.01175-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Orally Administered Erythromycin in Rainbow Trout (Oncorhynchus mykiss): Residues in Edible Tissues and Withdrawal Time
Annarita Esposito, Laura Fabrizi, Dario Lucchetti, Luigi Marvasi, Ettore Coni, and Emilio Guandalini
Antimicrob. Agents Chemother. March 2007 51: 1043-1047; published ahead of print December 28, 2006, doi:10.1128/AAC.01002-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Can Alcohol-Based Hand-Rub Solutions Cause You To Lose Your Driver's License? Comparative Cutaneous Absorption of Various Alcohols
T. L. Brown, S. Gamon, P. Tester, R. Martin, K. Hosking, G. C. Bowkett, D. Gerostamoulos, and M. L. Grayson
Antimicrob. Agents Chemother. March 2007 51: 1107-1108; published ahead of print December 28, 2006, doi:10.1128/AAC.01320-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Experimental Therapeutics:

Caspofungin in Combination with Amphotericin B against Candida parapsilosis
Francesco Barchiesi, Elisabetta Spreghini, Serena Tomassetti, Daniele Giannini, and Giorgio Scalise
Antimicrob. Agents Chemother. March 2007 51: 941-945; published ahead of print December 11, 2006, doi:10.1128/AAC.00880-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Once-Weekly Micafungin Therapy Is as Effective as Daily Therapy for Disseminated Candidiasis in Mice with Persistent Neutropenia
Tawanda Gumbo, George L. Drusano, Weiguo Liu, Robert W. Kulawy, Christine Fregeau, Vasha Hsu, and Arnold Louie
Antimicrob. Agents Chemother. March 2007 51: 968-974; published ahead of print December 28, 2006, doi:10.1128/AAC.01337-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Comparison of Itraconazole and Fluconazole Treatments in a Murine Model of Coccidioidal Meningitis
Perparim Kamberi, Raymond A. Sobel, Karl V. Clemons, Andreas Waldvogel, Joan M. Striebel, Paul L. Williams, and David A. Stevens
Antimicrob. Agents Chemother. March 2007 51: 998-1003; published ahead of print December 18, 2006, doi:10.1128/AAC.00332-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Synergistic Activity of R207910 Combined with Pyrazinamide against Murine Tuberculosis
M. Ibrahim, K. Andries, N. Lounis, A. Chauffour, C. Truffot-Pernot, V. Jarlier, and N. Veziris
Antimicrob. Agents Chemother. March 2007 51: 1011-1015; published ahead of print December 18, 2006, doi:10.1128/AAC.00898-06
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Pretreatment with Empty Liposomes Attenuates the Immunopathology of Invasive Pulmonary Aspergillosis in Corticosteroid-Immunosuppressed Mice
Russell E. Lewis, Georgios Chamilos, Randall A. Prince, and Dimitrios P. Kontoyiannis
Antimicrob. Agents Chemother. March 2007 51: 1078-1081; published ahead of print December 28, 2006, doi:10.1128/AAC.01268-06
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Evaluation of the In Vivo Activity of Tribendimidine against Schistosoma mansoni, Fasciola hepatica, Clonorchis sinensis, and Opisthorchis viverrini
Jennifer Keiser, Xiao Shu-Hua, Jacques Chollet, Marcel Tanner, and Jürg Utzinger
Antimicrob. Agents Chemother. March 2007 51: 1096-1098; published ahead of print December 28, 2006, doi:10.1128/AAC.01366-06
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Chemistry; Biosynthesis:

Cloning and Characterization of the Pyrrolomycin Biosynthetic Gene Clusters from Actinosporangium vitaminophilum ATCC 31673 and Streptomyces sp. Strain UC 11065
Xiujun Zhang and Ronald J. Parry
Antimicrob. Agents Chemother. March 2007 51: 946-957; published ahead of print December 11, 2006, doi:10.1128/AAC.01214-06
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Sequencing and Analysis of the Biosynthetic Gene Cluster of the Lipopeptide Antibiotic Friulimicin in Actinoplanes friuliensis
C. Müller, S. Nolden, P. Gebhardt, E. Heinzelmann, C. Lange, O. Puk, K. Welzel, W. Wohlleben, and D. Schwartz
Antimicrob. Agents Chemother. March 2007 51: 1028-1037; published ahead of print January 12, 2007, doi:10.1128/AAC.00942-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Biologic Response Modifiers:

Azithromycin Selectively Reduces Tumor Necrosis Factor Alpha Levels in Cystic Fibrosis Airway Epithelial Cells
Cristina Cigana, Baroukh Maurice Assael, and Paola Melotti
Antimicrob. Agents Chemother. March 2007 51: 975-981; published ahead of print January 8, 2007, doi:10.1128/AAC.01142-06
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Letters:

Oxazolidinones and Human Immunodeficiency Virus
Miguel G. Madariaga, Susan Swindells, and E. E. McKee
Antimicrob. Agents Chemother. March 2007 51: 1130
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Errata:

Restoration of Immune Response by a Cationic Amphiphilic Drug (AY 9944) In Vitro: A New Approach To Chemotherapy against Human Immunodeficiency Virus Type 1
Ammar Achour, Jean-Charles Landureau, Rosangela Salerno-Goncalves, Jean-Claude Mazière, and Daniel Zagury
Antimicrob. Agents Chemother. March 2007 51: 1131
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