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Guest Commentary:

Steven J. Projan

(Genome) Size Matters
Antimicrob. Agents Chemother. 2007 51: 1133-1134. [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Resistance:

Fabrizio Beltrametti, Arianna Consolandi, Lucia Carrano, Francesca Bagatin, Roberta Rossi, Livia Leoni, Elisabetta Zennaro, Enrico Selva, and Flavia Marinelli

Resistance to Glycopeptide Antibiotics in the Teicoplanin Producer Is Mediated by van Gene Homologue Expression Directing the Synthesis of a Modified Cell Wall Peptidoglycan
Antimicrob. Agents Chemother. 2007 51: 1135-1141. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Radoslaw Izdebski, Ewa Sadowy, Janusz Fiett, Pawel Grzesiowski, Marek Gniadkowski, and Waleria Hryniewicz

Clonal Diversity and Resistance Mechanisms in Tetracycline-Nonsusceptible Streptococcus pneumoniae Isolates in Poland
Antimicrob. Agents Chemother. 2007 51: 1155-1163. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

M. Zienkiewicz, I. Kern-Zdanowicz, M. Golebiewski, J. Zyliñska, P. Mieczkowski, M. Gniadkowski, J. Bardowski, and P. Ceglowski

Mosaic Structure of p1658/97, a 125-Kilobase Plasmid Harboring an Active Amplicon with the Extended-Spectrum ß-Lactamase Gene bla_SHV-5
Antimicrob. Agents Chemother. 2007 51: 1164-1171. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Lucia Pallecchi, Chiara Lucchetti, Alessandro Bartoloni, Filippo Bartalesi, Antonia Mantella, Herlan Gamboa, Alessandra Carattoli, Franco Paradisi, and Gian Maria Rossolini

Population Structure and Resistance Genes in Antibiotic-Resistant Bacteria from a Remote Community with Minimal Antibiotic Exposure
Antimicrob. Agents Chemother. 2007 51: 1179-1184. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Andrea Brenciani, Alessandro Bacciaglia, Manuela Vecchi, Luca A. Vitali, Pietro E. Varaldo, and Eleonora Giovanetti

Genetic Elements Carrying erm(B) in Streptococcus pyogenes and Association with tet(M) Tetracycline Resistance Gene
Antimicrob. Agents Chemother. 2007 51: 1209-1216. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jiunn-Jong Wu, Wen-Chien Ko, Shu-Huei Tsai, and Jing-Jou Yan

Prevalence of Plasmid-Mediated Quinolone Resistance Determinants QnrA, QnrB, and QnrS among Clinical Isolates of Enterobacter cloacae in a Taiwanese Hospital
Antimicrob. Agents Chemother. 2007 51: 1223-1227. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Paige M. Fox, Michael W. Climo, and Gordon L. Archer

Lack of Relationship between Purine Biosynthesis and Vancomycin Resistance in Staphylococcus aureus: a Cautionary Tale for Microarray Interpretation
Antimicrob. Agents Chemother. 2007 51: 1274-1280. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Johann D. D. Pitout, Deirdre L. Church, Daniel B. Gregson, Barbara L. Chow, Melissa McCracken, Michael R. Mulvey, and Kevin B. Laupland

Molecular Epidemiology of CTX-M-Producing Escherichia coli in the Calgary Health Region: Emergence of CTX-M-15-Producing Isolates
Antimicrob. Agents Chemother. 2007 51: 1281-1286. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hervé Nicoloff, Vincent Perreten, and Stuart B. Levy

Increased Genome Instability in Escherichia coli lon Mutants: Relation to Emergence of Multiple-Antibiotic-Resistant (Mar) Mutants Caused by Insertion Sequence Elements and Large Tandem Genomic Amplifications
Antimicrob. Agents Chemother. 2007 51: 1293-1303. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Frédéric Robin, Julien Delmas, Cédric Schweitzer, Olivier Tournilhac, Olivier Lesens, Catherine Chanal, and Richard Bonnet

Evolution of TEM-Type Enzymes: Biochemical and Genetic Characterization of Two New Complex Mutant TEM Enzymes, TEM-151 and TEM-152, from a Single Patient
Antimicrob. Agents Chemother. 2007 51: 1304-1309. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Véronique Dubois, Marie-Pierre Parizano, Corinne Arpin, Laure Coulange, Marie-Christine Bezian, and Claudine Quentin

High Genetic Stability of Integrons in Clinical Isolates of Shigella spp. of Worldwide Origin
Antimicrob. Agents Chemother. 2007 51: 1333-1340. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Anita Reinhardt, Thilo Köhler, Paul Wood, Peter Rohner, Jean-Luc Dumas, Bara Ricou, and Christian van Delden

Development and Persistence of Antimicrobial Resistance in Pseudomonas aeruginosa: a Longitudinal Observation in Mechanically Ventilated Patients
Antimicrob. Agents Chemother. 2007 51: 1341-1350. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Thierry Naas, Daniel Aubert, Ayla Özcan, and Patrice Nordmann

Chromosome-Encoded Narrow-Spectrum Ambler Class A ß-Lactamase GIL-1 from Citrobacter gillenii
Antimicrob. Agents Chemother. 2007 51: 1365-1372. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Li Xu, Jason Evans, Thomas Ling, Kathy Nye, and Peter Hawkey

Rapid Genotyping of CTX-M Extended-Spectrum ß-Lactamases by Denaturing High-Performance Liquid Chromatography
Antimicrob. Agents Chemother. 2007 51: 1446-1454. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Darija Viducic, Tsuneko Ono, Keiji Murakami, Mikiko Katakami, Heni Susilowati, and Yoichiro Miyake

rpoN Gene of Pseudomonas aeruginosa Alters Its Susceptibility to Quinolones and Carbapenems
Antimicrob. Agents Chemother. 2007 51: 1455-1462. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Paula Cerdá Zolezzi, Pilar Goñi Cepero, Joaquim Ruiz, Leticia Millán Laplana, Carmen Rubio Calvo, and Rafael Gómez-Lus

Molecular Epidemiology of Macrolide and Tetracycline Resistances in Commensal Gemella sp. Isolates
Antimicrob. Agents Chemother. 2007 51: 1487-1490. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sui Mae Lee, Miriam Ender, Rajan Adhikari, John M. B. Smith, Brigitte Berger-Bächi, and Gregory M. Cook

Fitness Cost of Staphylococcal Cassette Chromosome mec in Methicillin-Resistant Staphylococcus aureus by Way of Continuous Culture
Antimicrob. Agents Chemother. 2007 51: 1497-1499. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Seong Geun Hong, Ellen Smith Moland, Paul A. Wickman, Jennifer A. Black, Ashfaque Hossain, Nancy D. Hanson, and Kenneth S. Thomson

In Vitro Studies with DQ-113 and Comparison Fluoroquinolones To Determine Propensities To Select Resistance in Gram-Positive Cocci
Antimicrob. Agents Chemother. 2007 51: 1512-1514. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mariana Castanheira, Andrea S. Pereira, Adriana G. Nicoletti, Antônio C. C. Pignatari, Afonso L. Barth, and Ana C. Gales

First Report of Plasmid-Mediated qnrA1 in a Ciprofloxacin-Resistant Escherichia coli Strain in Latin America
Antimicrob. Agents Chemother. 2007 51: 1527-1529. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Stéphane Corvec, Laurent Poirel, Thierry Naas, Henri Drugeon, and Patrice Nordmann

Genetics and Expression of the Carbapenem-Hydrolyzing Oxacillinase Gene bla_OXA-23 in Acinetobacter baumannii
Antimicrob. Agents Chemother. 2007 51: 1530-1533. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Elvira Richter, Sabine Rüsch-Gerdes, and Doris Hillemann

First Linezolid-Resistant Clinical Isolates of Mycobacterium tuberculosis
Antimicrob. Agents Chemother. 2007 51: 1534-1536. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Patrícia Antunes, Jorge Machado, and Luísa Peixe

Dissemination of sul3-Containing Elements Linked to Class 1 Integrons with an Unusual 3' Conserved Sequence Region among Salmonella Isolates
Antimicrob. Agents Chemother. 2007 51: 1545-1548. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Maria Virginia Villegas, Karen Lolans, Adriana Correa, Juan Nicolas Kattan, Jaime A. Lopez, John P. Quinn and the Colombian Nosocomial Resistance Study Group

First Identification of Pseudomonas aeruginosa Isolates Producing a KPC-Type Carbapenem-Hydrolyzing ß-Lactamase
Antimicrob. Agents Chemother. 2007 51: 1553-1555. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

María Pérez-Vázquez, Federico Román, Silvia García-Cobos, and José Campos

Fluoroquinolone Resistance in Haemophilus influenzae Is Associated with Hypermutability
Antimicrob. Agents Chemother. 2007 51: 1566-1569. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jodi M. Thomson, Fabio Prati, Christopher R. Bethel, and Robert A. Bonomo

Use of Novel Boronic Acid Transition State Inhibitors To Probe Substrate Affinity in SHV-Type Extended-Spectrum ß-Lactamases
Antimicrob. Agents Chemother. 2007 51: 1577-1579. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Antiviral Agents:

Delia Susan-Resiga, Alice T. Bentley, Matthew D. Lynx, Darcy D. LaClair, and Edward E. McKee

Zidovudine Inhibits Thymidine Phosphorylation in the Isolated Perfused Rat Heart
Antimicrob. Agents Chemother. 2007 51: 1142-1149. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Y. Sunila Reddy, Susan L. Ford, Maggie T. Anderson, Sharon C. Murray, Judith Ng-Cashin, and Mark A. Johnson

Safety and Pharmacokinetics of Brecanavir, a Novel Human Immunodeficiency Virus Type 1 Protease Inhibitor, following Repeat Administration with and without Ritonavir in Healthy Adult Subjects
Antimicrob. Agents Chemother. 2007 51: 1202-1208. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jun Zhang, Eileen Rao, Marianna Dioszegi, Rama Kondru, Andre DeRosier, Eva Chan, Stephan Schwoerer, Nick Cammack, Michael Brandt, Surya Sankuratri, and Changhua Ji

The Second Extracellular Loop of CCR5 Contains the Dominant Epitopes for Highly Potent Anti-Human Immunodeficiency Virus Monoclonal Antibodies
Antimicrob. Agents Chemother. 2007 51: 1386-1397. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Miguel Stevens, Michela Pollicita, Christophe Pannecouque, Erik Verbeken, Oriana Tabarrini, Violetta Cecchetti, Stefano Aquaro, Carlo Federico Perno, Arnaldo Fravolini, Erik De Clercq, Dominique Schols, and Jan Balzarini

Novel In Vivo Model for the Study of Human Immunodeficiency Virus Type 1 Transcription Inhibitors: Evaluation of New 6-Desfluoroquinolone Derivatives
Antimicrob. Agents Chemother. 2007 51: 1407-1413. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Elena A. Govorkova, Natalia A. Ilyushina, David A. Boltz, Alan Douglas, Neziha Yilmaz, and Robert G. Webster

Efficacy of Oseltamivir Therapy in Ferrets Inoculated with Different Clades of H5N1 Influenza Virus
Antimicrob. Agents Chemother. 2007 51: 1414-1424. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Isabelle Pellegrin, Dominique Breilh, Gaelle Coureau, Sébastien Boucher, Didier Neau, Patrick Merel, Denis Lacoste, Hervé Fleury, Marie-Claude Saux, Jean-Luc Pellegrin, Estibaliz Lazaro, François Dabis, Rodolphe Thiébaut for the ANRS Co3 Aquitaine Cohort

Interpretation of Genotype and Pharmacokinetics for Resistance to Fosamprenavir-Ritonavir-Based Regimens in Antiretroviral-Experienced Patients
Antimicrob. Agents Chemother. 2007 51: 1473-1480. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Susceptibility:

Beth P. Goldstein, Deborah C. Draghi, Daniel J. Sheehan, Patricia Hogan, and Daniel F. Sahm

Bactericidal Activity and Resistance Development Profiling of Dalbavancin
Antimicrob. Agents Chemother. 2007 51: 1150-1154. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Michael D. Huband, Michael A. Cohen, Margaret Zurack, Debra L. Hanna, Laura A. Skerlos, Mark C. Sulavik, Glenn W. Gibson, Jeffrey W. Gage, Edmund Ellsworth, Michael A. Stier, and Stephen J. Gracheck

In Vitro and In Vivo Activities of PD 0305970 and PD 0326448, New Bacterial Gyrase/Topoisomerase Inhibitors with Potent Antibacterial Activities versus Multidrug-Resistant Gram-Positive and Fastidious Organism Groups
Antimicrob. Agents Chemother. 2007 51: 1191-1201. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ahmad Saleh, Johannes Friesen, Stefan Baumeister, Uwe Gross, and Wolfgang Bohne

Growth Inhibition of Toxoplasma gondii and Plasmodium falciparum by Nanomolar Concentrations of 1-Hydroxy-2-Dodecyl-4(1H)Quinolone, a High-Affinity Inhibitor of Alternative (Type II) NADH Dehydrogenases
Antimicrob. Agents Chemother. 2007 51: 1217-1222. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Emilio Pérez-Trallero, Milagrosa Montes, Beatriz Orden, Esther Tamayo, José M. García-Arenzana, and José M. Marimón

Phenotypic and Genotypic Characterization of Streptococcus pyogenes Isolates Displaying the MLS_B Phenotype of Macrolide Resistance in Spain, 1999 to 2005
Antimicrob. Agents Chemother. 2007 51: 1228-1233. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Michael J. Pucci, Jijun Cheng, Steven D. Podos, Christy L. Thoma, Jane A. Thanassi, Douglas D. Buechter, Gohar Mushtaq, Gerald A. Vigliotti, Jr., Barton J. Bradbury, and Milind Deshpande

In Vitro and In Vivo Antibacterial Activities of Heteroaryl Isothiazolones against Resistant Gram-Positive Pathogens
Antimicrob. Agents Chemother. 2007 51: 1259-1267. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Judy N. Chin, Michael J. Rybak, Chrissy M. Cheung, and Paul B. Savage

Antimicrobial Activities of Ceragenins against Clinical Isolates of Resistant Staphylococcus aureus
Antimicrob. Agents Chemother. 2007 51: 1268-1273. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jian He, Randal Eckert, Thanh Pharm, Maurice D. Simanian, Chuhong Hu, Daniel K. Yarbrough, Fengxia Qi, Maxwell H. Anderson, and Wenyuan Shi

Novel Synthetic Antimicrobial Peptides against Streptococcus mutans
Antimicrob. Agents Chemother. 2007 51: 1351-1358. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sang Hyun Cho, Saradee Warit, Baojie Wan, Chang Hwa Hwang, Guido F. Pauli, and Scott G. Franzblau

Low-Oxygen-Recovery Assay for High-Throughput Screening of Compounds against Nonreplicating Mycobacterium tuberculosis
Antimicrob. Agents Chemother. 2007 51: 1380-1385. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ronald N. Jones, Matthew G. Stilwell, Patricia A. Hogan, and Daniel J. Sheehan

Activity of Linezolid against 3,251 Strains of Uncommonly Isolated Gram-Positive Organisms: Report from the SENTRY Antimicrobial Surveillance Program
Antimicrob. Agents Chemother. 2007 51: 1491-1493. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Andrea Giacometti, Oscar Cirioni, Alessandra Riva, Wojciech Kamysz, Carmela Silvestri, Piotr Nadolski, Agnese Della Vittoria, Jerzy Lukasiak, and Giorgio Scalise

In Vitro Activity of Aurein 1.2 Alone and in Combination with Antibiotics against Gram-Positive Nosocomial Cocci
Antimicrob. Agents Chemother. 2007 51: 1494-1496. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mónica Azor, Josepa Gené, Josep Cano, and Josep Guarro

Universal In Vitro Antifungal Resistance of Genetic Clades of the Fusarium solani Species Complex
Antimicrob. Agents Chemother. 2007 51: 1500-1503. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kim Credito, Gengrong Lin, and Peter C. Appelbaum

Activity of Daptomycin Alone and in Combination with Rifampin and Gentamicin against Staphylococcus aureus Assessed by Time-Kill Methodology
Antimicrob. Agents Chemother. 2007 51: 1504-1507. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Kim Credito, Genrong Lin, and Peter C. Appelbaum

Antistaphylococcal Activity of DX-619 Alone and in Combination with Vancomycin, Teicoplanin, and Linezolid Assessed by Time-Kill Synergy Testing
Antimicrob. Agents Chemother. 2007 51: 1508-1511. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Hyun Woo Choi, Jong Hee Shin, Sook In Jung, Kyung Hwa Park, Duck Cho, Seung Jung Kee, Myung Geun Shin, Soon Pal Suh, and Dong Wook Ryang

Species-Specific Differences in the Susceptibilities of Biofilms Formed by Candida Bloodstream Isolates to Echinocandin Antifungals
Antimicrob. Agents Chemother. 2007 51: 1520-1523. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Christiane Gaudreau, Yves Girouard, Louise Ringuette, and Catherine Tsimiklis

Comparison of Disk Diffusion and Agar Dilution Methods for Erythromycin and Ciprofloxacin Susceptibility Testing of Campylobacter jejuni subsp. jejuni
Antimicrob. Agents Chemother. 2007 51: 1524-1526. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Elisabetta Iona, Federico Giannoni, Manuela Pardini, Lara Brunori, Graziella Orefici, and Lanfranco Fattorini

Metronidazole plus Rifampin Sterilizes Long-Term Dormant Mycobacterium tuberculosis
Antimicrob. Agents Chemother. 2007 51: 1537-1540. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Saima Aslam, Barbara W. Trautner, Venkat Ramanathan, and Rabih O. Darouiche

Combination of Tigecycline and N-Acetylcysteine Reduces Biofilm-Embedded Bacteria on Vascular Catheters
Antimicrob. Agents Chemother. 2007 51: 1556-1558. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Yu-Tsung Huang, Chun-Hsing Liao, Lee-Jeng Teng, and Po-Ren Hsueh

Daptomycin Susceptibility of Unusual Gram-Positive Bacteria: Comparison of Results Obtained by the Etest and the Broth Microdilution Method
Antimicrob. Agents Chemother. 2007 51: 1570-1572. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Vânia Lúcia Ribeiro da Matta, Márcia de Souza Carvalho Melhem, Arnaldo Lopes Colombo, Maria Luiza Moretti, Laura Rodero, Gisele Madeira Duboc de Almeida, Marilena dos Anjos Martins, Silvia Figueiredo Costa, Maria Beatriz G. Souza Dias, Márcio Nucci, and Anna S. Levin

Antifungal Drug Susceptibility Profile of Pichia anomala Isolates from Patients Presenting with Nosocomial Fungemia
Antimicrob. Agents Chemother. 2007 51: 1573-1576. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Analytical Procedures:

David J. Bacon, Christine Latour, Carmen Lucas, Olga Colina, Pascal Ringwald, and Stéphane Picot

Comparison of a SYBR Green I-Based Assay with a Histidine-Rich Protein II Enzyme-Linked Immunosorbent Assay for In Vitro Antimalarial Drug Efficacy Testing and Application to Clinical Isolates
Antimicrob. Agents Chemother. 2007 51: 1172-1178. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Experimental Therapeutics:

M. C. Lecaroz, M. J. Blanco-Prieto, M. A. Campanero, H. Salman, and C. Gamazo

Poly(D,L-Lactide-Coglycolide) Particles Containing Gentamicin: Pharmacokinetics and Pharmacodynamics in Brucella melitensis- Infected Mice
Antimicrob. Agents Chemother. 2007 51: 1185-1190. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Nigel Yarlett, W. Ray Waters, James A. Harp, Michael J. Wannemuehler, Mary Morada, Josephine Bellcastro, Steve J. Upton, Laurence J. Marton, and Benjamin J. Frydman

Activities of DL--Difluoromethylarginine and Polyamine Analogues against Cryptosporidium parvum Infection in a T-Cell Receptor Alpha-Deficient Mouse Model
Antimicrob. Agents Chemother. 2007 51: 1234-1239. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mohan Pammi Venkatesh, Don Pham, Mindy Fein, Lingkun Kong, and Leonard E. Weisman

Neonatal Coinfection Model of Coagulase-Negative Staphylococcus (Staphylococcus epidermidis) and Candida albicans: Fluconazole Prophylaxis Enhances Survival and Growth
Antimicrob. Agents Chemother. 2007 51: 1240-1245. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Russell E. Lewis, Guangling Liao, Jinggou Hou, Georgios Chamilos, Randall A. Prince, and Dimitrios P. Kontoyiannis

Comparative Analysis of Amphotericin B Lipid Complex and Liposomal Amphotericin B Kinetics of Lung Accumulation and Fungal Clearance in a Murine Model of Acute Invasive Pulmonary Aspergillosis
Antimicrob. Agents Chemother. 2007 51: 1253-1258. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Lauren M. Boak, Jian Li, Craig R. Rayner, and Roger L. Nation

Pharmacokinetic/Pharmacodynamic Factors Influencing Emergence of Resistance to Linezolid in an In Vitro Model
Antimicrob. Agents Chemother. 2007 51: 1287-1292. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

S. Segura, C. Gamazo, J. M. Irache, and S. Espuelas

Gamma Interferon Loaded onto Albumin Nanoparticles: In Vitro and In Vivo Activities against Brucella abortus
Antimicrob. Agents Chemother. 2007 51: 1310-1314. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Helen M. Kyriacou, Katie E. Steen, Ahmed Raza, Monica Arman, George Warimwe, Peter C. Bull, Ivan Havlik, and J. Alexandra Rowe

In Vitro Inhibition of Plasmodium falciparum Rosette Formation by Curdlan Sulfate
Antimicrob. Agents Chemother. 2007 51: 1321-1326. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Marcela L. Ferraz, Ricardo T. Gazzinelli, Rosana O. Alves, Julio A. Urbina, and Alvaro J. Romanha

The Anti-Trypanosoma cruzi Activity of Posaconazole in a Murine Model of Acute Chagas' Disease Is Less Dependent on Gamma Interferon than That of Benznidazole
Antimicrob. Agents Chemother. 2007 51: 1359-1364. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Henry S. Heine, Jennifer Bassett, Lynda Miller, Justin M. Hartings, Bruce E. Ivins, M. Louise Pitt, David Fritz, Sarah L. Norris, and W. Russell Byrne

Determination of Antibiotic Efficacy against Bacillus anthracis in a Mouse Aerosol Challenge Model
Antimicrob. Agents Chemother. 2007 51: 1373-1379. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Shu-Hua Xiao, Jennifer Keiser, Jacques Chollet, Jürg Utzinger, Yuxiang Dong, Yvette Endriss, Jonathan L. Vennerstrom, and Marcel Tanner

In Vitro and In Vivo Activities of Synthetic Trioxolanes against Major Human Schistosome Species
Antimicrob. Agents Chemother. 2007 51: 1440-1445. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

C. Andrew DeRyke, Mary Anne Banevicius, Hong Wei Fan, and David P. Nicolau

Bactericidal Activities of Meropenem and Ertapenem against Extended-Spectrum-ß-Lactamase-Producing Escherichia coli and Klebsiella pneumoniae in a Neutropenic Mouse Thigh Model
Antimicrob. Agents Chemother. 2007 51: 1481-1486. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Aldona L. Baltch, William J. Ritz, Lawrence H. Bopp, Phyllis B. Michelsen, and Raymond P. Smith

Antimicrobial Activities of Daptomycin, Vancomycin, and Oxacillin in Human Monocytes and of Daptomycin in Combination with Gentamicin and/or Rifampin in Human Monocytes and in Broth against Staphylococcus aureus
Antimicrob. Agents Chemother. 2007 51: 1559-1562. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Boris V. Nikonenko, Marina Protopopova, Rowena Samala, Leo Einck, and Carol A. Nacy

Drug Therapy of Experimental Tuberculosis (TB): Improved Outcome by Combining SQ109, a New Diamine Antibiotic, with Existing TB Drugs
Antimicrob. Agents Chemother. 2007 51: 1563-1565. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Pharmacology:

Christopher M. Rubino, Edmund V. Capparelli, John S. Bradley, Jeffrey L. Blumer, Gregory L. Kearns, Michael Reed, Richard F. Jacobs, Brenda Cirincione, and Dennis M. Grasela

Population Pharmacokinetic Model for Gatifloxacin in Pediatric Patients
Antimicrob. Agents Chemother. 2007 51: 1246-1252. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kerry L. LaPlante, Michael J. Rybak, Brian Tsuji, Thomas P. Lodise, and Glenn W. Kaatz

Fluoroquinolone Resistance in Streptococcus pneumoniae: Area Under the Concentration-Time Curve/MIC Ratio and Resistance Development with Gatifloxacin, Gemifloxacin, Levofloxacin, and Moxifloxacin
Antimicrob. Agents Chemother. 2007 51: 1315-1320. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Nils von Hentig, Axel Müller, Carsten Rottmann, Timo Wolf, Thomas Lutz, Stephan Klauke, Michael Kurowski, Bruno Oertel, Brenda Dauer, Sebastian Harder, and Schlomo Staszewski

Pharmacokinetics of Saquinavir, Atazanavir, and Ritonavir in a Twice-Daily Boosted Double-Protease Inhibitor Regimen
Antimicrob. Agents Chemother. 2007 51: 1431-1439. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Action:

Juan Román Luque-Ortega and Luis Rivas

Miltefosine (Hexadecylphosphocholine) Inhibits Cytochrome c Oxidase in Leishmania donovani Promastigotes
Antimicrob. Agents Chemother. 2007 51: 1327-1332. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Yuxin Chen, Michael T. Guarnieri, Adriana I. Vasil, Michael L. Vasil, Colin T. Mant, and Robert S. Hodges

Role of Peptide Hydrophobicity in the Mechanism of Action of -Helical Antimicrobial Peptides
Antimicrob. Agents Chemother. 2007 51: 1398-1406. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

M. Rakotomanga, S. Blanc, K. Gaudin, P. Chaminade, and P. M. Loiseau

Miltefosine Affects Lipid Metabolism in Leishmania donovani Promastigotes
Antimicrob. Agents Chemother. 2007 51: 1425-1430. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Françoise Benoit-Vical, Joël Lelièvre, Antoine Berry, Caroline Deymier, Odile Dechy-Cabaret, Jérôme Cazelles, Christophe Loup, Anne Robert, Jean-François Magnaval, and Bernard Meunier

Trioxaquines Are New Antimalarial Agents Active on All Erythrocytic Forms, Including Gametocytes
Antimicrob. Agents Chemother. 2007 51: 1463-1472. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Oana Dumitrescu, Sandrine Boisset, Cedric Badiou, Michele Bes, Yvonne Benito, Marie-Elisabeth Reverdy, François Vandenesch, Jerome Etienne, and Gerard Lina

Effect of Antibiotics on Staphylococcus aureus Producing Panton-Valentine Leukocidin
Antimicrob. Agents Chemother. 2007 51: 1515-1519. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Tom Coenye, Kris Honraet, Petra Rigole, Pol Nadal Jimenez, and Hans J. Nelis

In Vitro Inhibition of Streptococcus mutans Biofilm Formation on Hydroxyapatite by Subinhibitory Concentrations of Anthraquinones
Antimicrob. Agents Chemother. 2007 51: 1541-1544. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Chemistry; Biosynthesis:

Eric Vivien, Delphine Pitorre, Stéphane Cociancich, Isabelle Pieretti, Dean W. Gabriel, Philippe C. Rott, and Monique Royer

Heterologous Production of Albicidin: a Promising Approach to Overproducing and Characterizing This Potent Inhibitor of DNA Gyrase
Antimicrob. Agents Chemother. 2007 51: 1549-1552. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Letters:

James A. Karlowsky, Nancy M. Laing, Trish Baudry, Nachum Kaplan, David Vaughan, Daryl J. Hoban, and George G. Zhanel

In Vitro Activity of API-1252, a Novel FabI Inhibitor, against Clinical Isolates of Staphylococcus aureus and Staphylococcus epidermidis
Antimicrob. Agents Chemother. 2007 51: 1580-1581. [Full Text] [PDF] [Reprints and Permissions]  

Didier Hocquet, Micheline Roussel-Delvallez, Jean-Didier Cavallo, and Patrick Plésiat

MexAB-OprM- and MexXY-Overproducing Mutants Are Very Prevalent among Clinical Strains of Pseudomonas aeruginosa with Reduced Susceptibility to Ticarcillin
Antimicrob. Agents Chemother. 2007 51: 1582-1583. [Full Text] [PDF] [Reprints and Permissions]  

Pierre Bogaerts, Caroline Bauraing, A. Deplano, and Youri Glupczynski

Emergence and Dissemination of BEL-1-Producing Pseudomonas aeruginosa Isolates in Belgium
Antimicrob. Agents Chemother. 2007 51: 1584-1585. [Full Text] [PDF] [Reprints and Permissions]  

Errata:

Hend Hanna, Paul Bahna, Ruth Reitzel, Tanya Dvorak, Gassan Chaiban, Ray Hachem, and Issam Raad

Comparative In Vitro Efficacies and Antimicrobial Durabilities of Novel Antimicrobial Central Venous Catheters
Antimicrob. Agents Chemother. 2007 51: 1586. [Full Text] [PDF] [Reprints and Permissions]  

Matthieu Prot, Laurence Heripret, Nathalie Cardot-Leccia, Christophe Perrin, Myriam Aouadi, Thibaud Lavrut, Rodolphe Garraffo, Pierre Dellamonica, Jacques Durant, Yannick Le Marchand-Brustel, and Bernard Binétruy

Long-Term Treatment with Lopinavir-Ritonavir Induces a Reduction in Peripheral Adipose Depots in Mice
Antimicrob. Agents Chemother. 2007 51: 1587. [Full Text] [PDF] [Reprints and Permissions]  

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