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Minireviews:

Karl Drlica, Muhammad Malik, Robert J. Kerns, and Xilin Zhao

Quinolone-Mediated Bacterial Death
Antimicrob. Agents Chemother. 2008 52: 385-392. [Full Text] [PDF] [Reprints and Permissions]  

Antiviral Agents:

Agnieszka Gozdek, Igor Zhukov, Agnieszka Polkowska, Jaroslaw Poznanski, Anna Stankiewicz-Drogon, Jerzy M. Pawlowicz, Wlodzimierz Zagórski-Ostoja, Peter Borowski, and Anna M. Boguszewska-Chachulska

NS3 Peptide, a Novel Potent Hepatitis C Virus NS3 Helicase Inhibitor: Its Mechanism of Action and Antiviral Activity in the Replicon System
Antimicrob. Agents Chemother. 2008 52: 393-401. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Eisuke Murakami, Congrong Niu, Haiying Bao, Holly M. Micolochick Steuer, Tony Whitaker, Tammy Nachman, Michael A. Sofia, Peiyuan Wang, Michael J. Otto, and Phillip A. Furman

The Mechanism of Action of β-D-2'-Deoxy-2'-Fluoro-2'-C-Methylcytidine Involves a Second Metabolic Pathway Leading to β-D-2'-Deoxy-2'-Fluoro-2'-C-Methyluridine 5'-Triphosphate, a Potent Inhibitor of the Hepatitis C Virus RNA-Dependent RNA Polymerase
Antimicrob. Agents Chemother. 2008 52: 458-464. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kenneth H. Fife, Tze-Chiang Meng, Daron G. Ferris, and Ping Liu

Effect of Resiquimod 0.01% Gel on Lesion Healing and Viral Shedding When Applied to Genital Herpes Lesions
Antimicrob. Agents Chemother. 2008 52: 477-482. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sidonie Lambert-Niclot, Philippe Flandre, Ana Canestri, Gilles Peytavin, Christine Blanc, Rachid Agher, Cathia Soulié, Marc Wirden, Christine Katlama, Vincent Calvez, and Anne-Geneviève Marcelin

Factors Associated with the Selection of Mutations Conferring Resistance to Protease Inhibitors (PIs) in PI-Experienced Patients Displaying Treatment Failure on Darunavir
Antimicrob. Agents Chemother. 2008 52: 491-496. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Gadi Borkow, Humberto H. Lara, Chandice Y. Covington, Adeline Nyamathi, and Jeffrey Gabbay

Deactivation of Human Immunodeficiency Virus Type 1 in Medium by Copper Oxide-Containing Filters
Antimicrob. Agents Chemother. 2008 52: 518-525. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Susan L. Ford, Ya-Chi Chen, Yu Lou, Julie Borland, Sherene S. Min, Geoffrey J. Yuen, and Mark J. Shelton

Pharmacokinetic Interaction between Fosamprenavir-Ritonavir and Rifabutin in Healthy Subjects
Antimicrob. Agents Chemother. 2008 52: 534-538. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Wendy C. Magee, Kathy A. Aldern, Karl Y. Hostetler, and David H. Evans

Cidofovir and (S)-9-[3-Hydroxy-(2-Phosphonomethoxy)Propyl]Adenine Are Highly Effective Inhibitors of Vaccinia Virus DNA Polymerase When Incorporated into the Template Strand
Antimicrob. Agents Chemother. 2008 52: 586-597. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Charles E. Mazzucco, Robert K. Hamatake, Richard J. Colonno, and Daniel J. Tenney

Entecavir for Treatment of Hepatitis B Virus Displays No In Vitro Mitochondrial Toxicity or DNA Polymerase Gamma Inhibition
Antimicrob. Agents Chemother. 2008 52: 598-605. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jennifer J. Kiser, Courtney V. Fletcher, Patricia M. Flynn, Coleen K. Cunningham, Craig M. Wilson, Bill G. Kapogiannis, Hanna Major-Wilson, Rolando M. Viani, Nancy X. Liu, Larry R. Muenz, D. Robert Harris, Peter L. Havens and the Adolescent Trials Network for HIV/AIDS Interventions

Pharmacokinetics of Antiretroviral Regimens Containing Tenofovir Disoproxil Fumarate and Atazanavir-Ritonavir in Adolescents and Young Adults with Human Immunodeficiency Virus Infection
Antimicrob. Agents Chemother. 2008 52: 631-637. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Adrian S. Ray, Jennifer E. Vela, Constantine G. Boojamra, Lijun Zhang, Hon Hui, Christian Callebaut, Kirsten Stray, Kuei-Ying Lin, Ying Gao, Richard L. Mackman, and Tomas Cihlar

Intracellular Metabolism of the Nucleotide Prodrug GS-9131, a Potent Anti-Human Immunodeficiency Virus Agent
Antimicrob. Agents Chemother. 2008 52: 648-654. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Tomas Cihlar, Adrian S. Ray, Constantine G. Boojamra, Lijun Zhang, Hon Hui, Genevieve Laflamme, Jennifer E. Vela, Deborah Grant, James Chen, Florence Myrick, Kirsten L. White, Ying Gao, Kuei-Ying Lin, Janet L. Douglas, Neil T. Parkin, Anne Carey, Rowchanak Pakdaman, and Richard L. Mackman

Design and Profiling of GS-9148, a Novel Nucleotide Analog Active against Nucleoside-Resistant Variants of Human Immunodeficiency Virus Type 1, and Its Orally Bioavailable Phosphonoamidate Prodrug, GS-9131
Antimicrob. Agents Chemother. 2008 52: 655-665. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Yingjia Zhang, Peter Weady, Rohit Duggal, and Weidong Hao

Novel Chimeric Genotype 1b/2a Hepatitis C Virus Suitable for High-Throughput Screening
Antimicrob. Agents Chemother. 2008 52: 666-674. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Stephanie T. Shi, Koleen J. Herlihy, Joanne P. Graham, Shella A. Fuhrman, Chau Doan, Hans Parge, Michael Hickey, Jingjin Gao, Xiu Yu, Fannie Chau, Javier Gonzalez, Hui Li, Cristina Lewis, Amy K. Patick, and Rohit Duggal

In Vitro Resistance Study of AG-021541, a Novel Nonnucleoside Inhibitor of the Hepatitis C Virus RNA-Dependent RNA Polymerase
Antimicrob. Agents Chemother. 2008 52: 675-683. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Rie Tanaka, Hideji Hanabusa, Ei Kinai, Naoki Hasegawa, Masayoshi Negishi, and Shingo Kato

Intracellular Efavirenz Levels in Peripheral Blood Mononuclear Cells from Human Immunodeficiency Virus-Infected Individuals
Antimicrob. Agents Chemother. 2008 52: 782-785. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Action:

Arunasalam Naguleswaran, Arsenio M. Fialho, Anita Chaudhari, Chang Soo Hong, Ananda M. Chakrabarty, and William J. Sullivan, Jr.

Azurin-Like Protein Blocks Invasion of Toxoplasma gondii through Potential Interactions with Parasite Surface Antigen SAG1
Antimicrob. Agents Chemother. 2008 52: 402-408. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Audrey Bellemare, Nathalie Vernoux, Dany Morisset, and Yves Bourbonnais

Human Pre-Elafin Inhibits a Pseudomonas aeruginosa-Secreted Peptidase and Prevents Its Proliferation in Complex Media
Antimicrob. Agents Chemother. 2008 52: 483-490. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Woong Sik Jang, Xuewei Serene Li, Jianing N. Sun, and Mira Edgerton

The P-113 Fragment of Histatin 5 Requires a Specific Peptide Sequence for Intracellular Translocation in Candida albicans, Which Is Independent of Cell Wall Binding
Antimicrob. Agents Chemother. 2008 52: 497-504. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Karima El Fadili, Michaël Imbeault, Nadine Messier, Gaétan Roy, Benjamin Gourbal, Marc Bergeron, Michel J. Tremblay, Danielle Légaré, and Marc Ouellette

Modulation of Gene Expression in Human Macrophages Treated with the Anti-Leishmania Pentavalent Antimonial Drug Sodium Stibogluconate
Antimicrob. Agents Chemother. 2008 52: 526-533. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Judicaël Parisot, Sarah Carey, Eefjan Breukink, Weng C. Chan, Arjan Narbad, and Boyan Bonev

Molecular Mechanism of Target Recognition by Subtilin, a Class I Lanthionine Antibiotic
Antimicrob. Agents Chemother. 2008 52: 612-618. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

D. Caridha, D. Yourick, M. Cabezas, L. Wolf, T. H. Hudson, and G. S. Dow

Mefloquine-Induced Disruption of Calcium Homeostasis in Mammalian Cells Is Similar to That Induced by Ionomycin
Antimicrob. Agents Chemother. 2008 52: 684-693. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Sanjay Kumar, Sajal Kumar Das, Sumanta Dey, Pallab Maity, Mithu Guha, Vinay Choubey, Gautam Panda, and Uday Bandyopadhyay

Antiplasmodial Activity of [(Aryl)arylsulfanylmethyl]Pyridine
Antimicrob. Agents Chemother. 2008 52: 705-715. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

G. Chamilos, R. E. Lewis, G. Lamaris, T. J. Walsh, and D. P. Kontoyiannis

Zygomycetes Hyphae Trigger an Early, Robust Proinflammatory Response in Human Polymorphonuclear Neutrophils through Toll-Like Receptor 2 Induction but Display Relative Resistance to Oxidative Damage
Antimicrob. Agents Chemother. 2008 52: 722-724. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Diana Barthel, Martin Schlitzer, and Gabriele Pradel

Telithromycin and Quinupristin-Dalfopristin Induce Delayed Death in Plasmodium falciparum
Antimicrob. Agents Chemother. 2008 52: 774-777. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Susceptibility:

Shujuan Sun, Yan Li, Qiongjie Guo, Changwen Shi, Jinlong Yu, and Lin Ma

In Vitro Interactions between Tacrolimus and Azoles against Candida albicans Determined by Different Methods
Antimicrob. Agents Chemother. 2008 52: 409-417. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sung Jae Shin and Michael T. Collins

Thiopurine Drugs Azathioprine and 6-Mercaptopurine Inhibit Mycobacterium paratuberculosis Growth In Vitro
Antimicrob. Agents Chemother. 2008 52: 418-426. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ursula Fürnkranz, Markus Nagl, Waldemar Gottardi, Martina Köhsler, Horst Aspöck, and Julia Walochnik

Cytotoxic Activity of N-Chlorotaurine on Acanthamoeba spp.
Antimicrob. Agents Chemother. 2008 52: 470-476. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sabrina Sonda, Sasa Stefanic, and Adrian B. Hehl

A Sphingolipid Inhibitor Induces a Cytokinesis Arrest and Blocks Stage Differentiation in Giardia lamblia
Antimicrob. Agents Chemother. 2008 52: 563-569. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Venkata M. Reddy, Leo Einck, and Carol A. Nacy

In Vitro Antimycobacterial Activities of Capuramycin Analogues
Antimicrob. Agents Chemother. 2008 52: 719-721. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Rita Marimon, Carolina Serena, Josepa Gené, Josep Cano, and Josep Guarro

In Vitro Antifungal Susceptibilities of Five Species of Sporothrix
Antimicrob. Agents Chemother. 2008 52: 732-734. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Robert L. Holmes and James H. Jorgensen

Inhibitory Activities of 11 Antimicrobial Agents and Bactericidal Activities of Vancomycin and Daptomycin against Invasive Methicillin-Resistant Staphylococcus aureus Isolates Obtained from 1999 through 2006
Antimicrob. Agents Chemother. 2008 52: 757-760. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ellie J. C. Goldstein, Diane M. Citron, C. Vreni Merriam, Yumi A. Warren, Kerin L. Tyrrell, and Helen T. Fernandez

In Vitro Activities of Doripenem and Six Comparator Drugs against 423 Aerobic and Anaerobic Bacterial Isolates from Infected Diabetic Foot Wounds
Antimicrob. Agents Chemother. 2008 52: 761-766. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Juliana S. Argenta, Janio M. Santurio, Sydney H. Alves, Daniela I. B. Pereira, Ayrton S. Cavalheiro, Andréia Spanamberg, and Laerte Ferreiro

In Vitro Activities of Voriconazole, Itraconazole, and Terbinafine Alone or in Combination against Pythium insidiosum Isolates from Brazil
Antimicrob. Agents Chemother. 2008 52: 767-769. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

E. Dannaoui, O. Lortholary, D. Raoux, M. E. Bougnoux, G. Galeazzi, C. Lawrence, D. Moissenet, I. Poilane, D. Hoinard, F. Dromer and the YEASTS Group

Comparative In Vitro Activities of Caspofungin and Micafungin, Determined Using the Method of the European Committee on Antimicrobial Susceptibility Testing, against Yeast Isolates Obtained in France in 2005-2006
Antimicrob. Agents Chemother. 2008 52: 778-781. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Experimental Therapeutics:

Sreedhar Subramanian, Carol L. Roberts, C. Anthony Hart, Helen M. Martin, Steve W. Edwards, Jonathan M. Rhodes, and Barry J. Campbell

Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics
Antimicrob. Agents Chemother. 2008 52: 427-434. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Elisabetta Spreghini, Carmelo Massimo Maida, Maria Eleonora Milici, Giorgio Scalise, and Francesco Barchiesi

Posaconazole Activity against Candida glabrata after Exposure to Caspofungin or Amphotericin B
Antimicrob. Agents Chemother. 2008 52: 513-517. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

D. Andes, D. J. Diekema, M. A. Pfaller, R. A. Prince, K. Marchillo, J. Ashbeck, and J. Hou

In Vivo Pharmacodynamic Characterization of Anidulafungin in a Neutropenic Murine Candidiasis Model
Antimicrob. Agents Chemother. 2008 52: 539-550. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Resistance:

Nicole Wolter, Anthony M. Smith, David J. Farrell, John Blackman Northwood, Stephen Douthwaite, and Keith P. Klugman

Telithromycin Resistance in Streptococcus pneumoniae Is Conferred by a Deletion in the Leader Sequence of erm(B) That Increases rRNA Methylation
Antimicrob. Agents Chemother. 2008 52: 435-440. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

David S. Hammond, Tegan Harris, Jan Bell, John Turnidge, and Philip M. Giffard

Selection of SHV Extended-Spectrum-β-Lactamase-Dependent Cefotaxime and Ceftazidime Resistance in Klebsiella pneumoniae Requires a Plasmid-Borne bla_SHV Gene
Antimicrob. Agents Chemother. 2008 52: 441-445. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Wenming Zhu, Nancye C. Clark, Linda K. McDougal, Jeffery Hageman, L. Clifford McDonald, and Jean B. Patel

Vancomycin-Resistant Staphylococcus aureus Isolates Associated with Inc18-Like vanA Plasmids in Michigan
Antimicrob. Agents Chemother. 2008 52: 452-457. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Krzysztof Sieradzki, Marilyn Chung, and Alexander Tomasz

Role of a Sodium-Dependent Symporter Homologue in the Thermosensitivity of β-Lactam Antibiotic Resistance and Cell Wall Composition in Staphylococcus aureus
Antimicrob. Agents Chemother. 2008 52: 505-512. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Djalal Meziane-Cherif, Dominique Decré, E. Arne Høiby, Patrice Courvalin, and Bruno Périchon

Genetic and Biochemical Characterization of CAD-1, a Chromosomally Encoded New Class A Penicillinase from Carnobacterium divergens
Antimicrob. Agents Chemother. 2008 52: 551-556. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Laurence Damier-Piolle, Sophie Magnet, Sylvie Brémont, Thierry Lambert, and Patrice Courvalin

AdeIJK, a Resistance-Nodulation-Cell Division Pump Effluxing Multiple Antibiotics in Acinetobacter baumannii
Antimicrob. Agents Chemother. 2008 52: 557-562. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mariana Castanheira, Hélio S. Sader, Lalitagauri M. Deshpande, Thomas R. Fritsche, and Ronald N. Jones

Antimicrobial Activities of Tigecycline and Other Broad-Spectrum Antimicrobials Tested against Serine Carbapenemase- and Metallo-β-Lactamase-Producing Enterobacteriaceae: Report from the SENTRY Antimicrobial Surveillance Program
Antimicrob. Agents Chemother. 2008 52: 570-573. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mi-Jung Kim, Ikuo Hirono, Ken Kurokawa, Takeshi Maki, John Hawke, Hidehiro Kondo, Mudjekeewis D. Santos, and Takashi Aoki

Complete DNA Sequence and Analysis of the Transferable Multiple-Drug Resistance Plasmids (R Plasmids) from Photobacterium damselae subsp. piscicida Isolates Collected in Japan and the United States
Antimicrob. Agents Chemother. 2008 52: 606-611. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Romina Camilli, Maria Del Grosso, Francesco Iannelli, and Annalisa Pantosti

New Genetic Element Carrying the Erythromycin Resistance Determinant erm(TR) in Streptococcus pneumoniae
Antimicrob. Agents Chemother. 2008 52: 619-625. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Efthymia Petinaki, Véronique Guérin-Faublée, Vianney Pichereau, Corinne Villers, Adeline Achard, Brigitte Malbruny, and Roland Leclercq

Lincomycin Resistance Gene lnu(D) in Streptococcus uberis
Antimicrob. Agents Chemother. 2008 52: 626-630. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Gilad Bachrach, Hamutal Altman, Paul E. Kolenbrander, Natalia I. Chalmers, Michal Gabai-Gutner, Amram Mor, Michael Friedman, and Doron Steinberg

Resistance of Porphyromonas gingivalis ATCC 33277 to Direct Killing by Antimicrobial Peptides Is Protease Independent
Antimicrob. Agents Chemother. 2008 52: 638-642. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Takaji Fujimura and Kazuhisa Murakami

Staphylococcus aureus Clinical Isolate with High-Level Methicillin Resistance with an lytH Mutation Caused by IS1182 Insertion
Antimicrob. Agents Chemother. 2008 52: 643-647. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ritu Pasrija, Sneh Lata Panwar, and Rajendra Prasad

Multidrug Transporters CaCdr1p and CaMdr1p of Candida albicans Display Different Lipid Specificities: both Ergosterol and Sphingolipids Are Essential for Targeting of CaCdr1p to Membrane Rafts
Antimicrob. Agents Chemother. 2008 52: 694-704. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Medea Gegia, Nino Mdivani, Rodrigo E. Mendes, Haijing Li, Maka Akhalaia, Jian Han, George Khechinashvili, and Yi-Wei Tang

Prevalence of and Molecular Basis for Tuberculosis Drug Resistance in the Republic of Georgia: Validation of a QIAplex System for Detection of Drug Resistance-Related Mutations
Antimicrob. Agents Chemother. 2008 52: 725-729. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Zhiyong Zhou, Sean M. Griffing, Alexandre Macedo de Oliveira, Andrea M. McCollum, Wilmer Marquino Quezada, Nancy Arrospide, Ananias A. Escalante, and Venkatachalam Udhayakumar

Decline in Sulfadoxine-Pyrimethamine-Resistant Alleles after Change in Drug Policy in the Amazon Region of Peru
Antimicrob. Agents Chemother. 2008 52: 739-741. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

S. Dégrange, H. Renaudin, A. Charron, C. Bébéar, and C. M. Bébéar

Tetracycline Resistance in Ureaplasma spp. and Mycoplasma hominis: Prevalence in Bordeaux, France, from 1999 to 2002 and Description of Two tet(M)-Positive Isolates of M. hominis Susceptible to Tetracyclines
Antimicrob. Agents Chemother. 2008 52: 742-744. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Stéphanie Matrat, Emmanuelle Cambau, Vincent Jarlier, and Alexandra Aubry

Are All the DNA Gyrase Mutations Found in Mycobacterium leprae Clinical Strains Involved in Resistance to Fluoroquinolones?
Antimicrob. Agents Chemother. 2008 52: 745-747. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Klaudia Kosowska-Shick, Catherine Clark, Kim Credito, Bonifacio Dewasse, Linda Beachel, Lois Ednie, and Peter C. Appelbaum

In Vitro Capability of Faropenem To Select for Resistant Mutants of Streptococcus pneumoniae and Haemophilus influenzae
Antimicrob. Agents Chemother. 2008 52: 748-752. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Sara Thulin, Per Olcén, Hans Fredlund, and Magnus Unemo

Combined Real-Time PCR and Pyrosequencing Strategy for Objective, Sensitive, Specific, and High-Throughput Identification of Reduced Susceptibility to Penicillins in Neisseria meningitidis
Antimicrob. Agents Chemother. 2008 52: 753-756. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Patrizia Spigaglia, Fabrizio Barbanti, and Paola Mastrantonio

Tetracycline Resistance Gene tet(W) in the Pathogenic Bacterium Clostridium difficile
Antimicrob. Agents Chemother. 2008 52: 770-773. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Muriel Galas, Jean-Winoc Decousser, Nelly Breton, Thierry Godard, Pierre Yves Allouch, Patrick Pina and the Collège de Bactériologie Virologie Hygiène (ColBVH) Study Group

Nationwide Study of the Prevalence, Characteristics, and Molecular Epidemiology of Extended-Spectrum-β-Lactamase-Producing Enterobacteriaceae in France
Antimicrob. Agents Chemother. 2008 52: 786-789. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Caspar Franzen and Bernd Salzberger

Analysis of the β-Tubulin Gene from Vittaforma corneae Suggests Benzimidazole Resistance
Antimicrob. Agents Chemother. 2008 52: 790-793. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Clinical Therapeutics:

K. W. Garey, D. Lai, T. K. Dao-Tran, L. O. Gentry, L. Y. Hwang, and B. R. Davis

Interrupted Time Series Analysis of Vancomycin Compared to Cefuroxime for Surgical Prophylaxis in Patients Undergoing Cardiac Surgery
Antimicrob. Agents Chemother. 2008 52: 446-451. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

David L. Paterson, Carlene A. Muto, Magdaline Ndirangu, Peter K. Linden, Brian A. Potoski, Blair Capitano, Robert A. Bonomo, David C. Aron, and Curtis J. Donskey

Acquisition of Rectal Colonization by Vancomycin-Resistant Enterococcus among Intensive Care Unit Patients Treated with Piperacillin-Tazobactam versus Those Receiving Cefepime-Containing Antibiotic Regimens
Antimicrob. Agents Chemother. 2008 52: 465-469. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Dimitrios P. Kontoyiannis, Russell E. Lewis, Barbara D. Alexander, Olivier Lortholary, Françoise Dromer, Krishan L. Gupta, George T. John, Ramon del Busto, Goran B. Klintmalm, Jyoti Somani, G. Marshall Lyon, Kenneth Pursell, Valentina Stosor, Patricia Munoz, Ajit P. Limaye, Andre C. Kalil, Timothy L. Pruett, Julia Garcia-Diaz, Atul Humar, Sally Houston, Andrew A. House, Dannah Wray, Susan Orloff, Lorraine A. Dowdy, Robert A. Fisher, Joseph Heitman, Nathaniel D. Albert, Marilyn M. Wagener, and Nina Singh

Calcineurin Inhibitor Agents Interact Synergistically with Antifungal Agents In Vitro against Cryptococcus neoformans Isolates: Correlation with Outcome in Solid Organ Transplant Recipients with Cryptococcosis
Antimicrob. Agents Chemother. 2008 52: 735-738. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Chemistry; Biosynthesis:

Xiujun Zhang, Lawrence B. Alemany, Hans-Peter Fiedler, Michael Goodfellow, and Ronald J. Parry

Biosynthetic Investigations of Lactonamycin and Lactonamycin Z: Cloning of the Biosynthetic Gene Clusters and Discovery of an Unusual Starter Unit
Antimicrob. Agents Chemother. 2008 52: 574-585. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Biologic Response Modifiers:

Gerardo Quezada, Nadezhda V. Koshkina, Patrick Zweidler-McKay, Zichao Zhou, Dimitrios P. Kontoyiannis, and Eugenie S. Kleinerman

Intranasal Granulocyte-Macrophage Colony-Stimulating Factor Reduces the Aspergillus Burden in an Immunosuppressed Murine Model of Pulmonary Aspergillosis
Antimicrob. Agents Chemother. 2008 52: 716-718. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Analytical Procedures:

David Zhuang, Melinda Smedema, Ann LeMonte, Benita K. Book, Mark D. Pescovitz, and L. Joseph Wheat

Effect of Calcineurin Inhibitors on Posaconazole Blood Levels as Measured by the MVista Microbiological Assay
Antimicrob. Agents Chemother. 2008 52: 730-731. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Letters:

Zhiyong Zong, Sally R. Partridge, and Jonathan R. Iredell

RmtC 16S rRNA Methyltransferase in Australia
Antimicrob. Agents Chemother. 2008 52: 794-795. [Full Text] [PDF] [Reprints and Permissions]  

Gaelle Cuzon, Thierry Naas, Marie Claude Demachy, and Patrice Nordmann

Plasmid-Mediated Carbapenem-Hydrolyzing β-Lactamase KPC-2 in Klebsiella pneumoniae Isolate from Greece
Antimicrob. Agents Chemother. 2008 52: 796-797. [Full Text] [PDF] [Reprints and Permissions]  

Rodrigo E. Mendes, Jan M. Bell, John D. Turnidge, Qiwen Yang, Yunsong Yu, Ziyong Sun, and Ronald N. Jones

Carbapenem-Resistant Isolates of Klebsiella pneumoniae in China and Detection of a Conjugative Plasmid (bla_KPC-2 plus qnrB4) and a bla_IMP-4 Gene
Antimicrob. Agents Chemother. 2008 52: 798-799. [Full Text] [PDF] [Reprints and Permissions]  

Doris Hillemann, Sabine Rüsch-Gerdes, and Elvira Richter

In Vitro-Selected Linezolid-Resistant Mycobacterium tuberculosis Mutants
Antimicrob. Agents Chemother. 2008 52: 800-801. [Full Text] [PDF] [Reprints and Permissions]  

Bhaswati Sen, Manjira Bhattacharya, and Swapan K. Niyogi

In Vitro Activity of Cefpodoxime, an Expanded-Spectrum Cephalosporin, against Salmonella enterica Serotype Typhi
Antimicrob. Agents Chemother. 2008 52: 802-803. [Full Text] [PDF] [Reprints and Permissions]  

Sheng-Chiang Su, L. K. Siu, Ling Ma, Kuo-Ming Yeh, Chang-Phone Fung, Jung-Chung Lin, and Feng-Yee Chang

Community-Acquired Liver Abscess Caused by Serotype K1 Klebsiella pneumoniae with CTX-M-15-Type Extended-Spectrum β-Lactamase
Antimicrob. Agents Chemother. 2008 52: 804-805. [Full Text] [PDF] [Reprints and Permissions]  

Nicolás F. Cordeiro, Luciana Robino, Julio Medina, Verónica Seija, Inés Bado, Virginia García, Maximiliano Berro, Julio Pontet, Lucía López, Cristina Bazet, Gloria Rieppi, Gabriel Gutkind, Juan A. Ayala, and Rafael Vignoli

Ciprofloxacin-Resistant Enterobacteria Harboring the aac(6')-Ib-cr Variant Isolated from Feces of Inpatients in an Intensive Care Unit in Uruguay
Antimicrob. Agents Chemother. 2008 52: 806-807. [Full Text] [PDF] [Reprints and Permissions]  

Author's Correction:

Vincent Jullien, Jean-Marc Tréluyer, Elisabeth Rey, Patrick Jaffray, Anne Krivine, Laurence Moachon, Agnès Lillo-Le Louet, Anne Lescoat, Nicolas Dupin, Dominique Salmon, Gérard Pons, and Saïk Urien

Population Pharmacokinetics of Tenofovir in Human Immunodeficiency Virus-Infected Patients Taking Highly Active Antiretroviral Therapy
Antimicrob. Agents Chemother. 2008 52: 808. [Full Text] [PDF] [Reprints and Permissions]  

Hesna Yigit, Anne Marie Queenan, Gregory J. Anderson, Antonio Domenech-Sanchez, James W. Biddle, Christine D. Steward, Sebastian Alberti, Karen Bush, and Fred C. Tenover

Novel Carbapenem-Hydrolyzing β-Lactamase, KPC-1, from a Carbapenem-Resistant Strain of Klebsiella pneumoniae
Antimicrob. Agents Chemother. 2008 52: 809. [Full Text] [PDF] [Reprints and Permissions]  

James S. Lewis, II, Monica Herrera, Brian Wickes, Jan E. Patterson, and James H. Jorgensen

First Report of the Emergence of CTX-M-Type Extended-Spectrum β-Lactamases (ESBLs) as the Predominant ESBL Isolated in a U.S. Health Care System
Antimicrob. Agents Chemother. 2008 52: 810. [Full Text] [PDF] [Reprints and Permissions]  

Martin S. King, Richard Rode, Isabelle Cohen-Codar, Vincent Calvez, Anne-Geneviève Marcelin, George J. Hanna, and Dale J. Kempf

Predictive Genotypic Algorithm for Virologic Response to Lopinavir-Ritonavir in Protease Inhibitor-Experienced Patients
Antimicrob. Agents Chemother. 2008 52: 811. [Full Text] [PDF] [Reprints and Permissions]  

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