AAC -- Table of Contents (February 1 2008, 52 [2])

Receive this page by e-mail each issue: [Sign up for eTOCs]

Contents: February 2008, Volume 52, Issue 2

       Minireviews

       Antiviral Agents

       Mechanisms of Action

       Susceptibility

       Experimental Therapeutics

       Mechanisms of Resistance

       Clinical Therapeutics

       Chemistry; Biosynthesis

       Biologic Response Modifiers

       Analytical Procedures

       Letters

       Author's Correction

Other Issues

FREE CONTENT FROM ASM

AUTHOR-SPONSORED OPEN ACCESS

Table of Contents

[Index by Author]

Table of Contents (PDF) »

To see an article, click its [Full Text], [Abstract] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

Minireviews:

Quinolone-Mediated Bacterial Death
Karl Drlica, Muhammad Malik, Robert J. Kerns, and Xilin Zhao
Antimicrob. Agents Chemother. February 2008 52: 385-392; published ahead of print August 27, 2007, doi:10.1128/AAC.01617-06
[Full Text] [PDF] [Reprints and Permissions]

Antiviral Agents:

NS3 Peptide, a Novel Potent Hepatitis C Virus NS3 Helicase Inhibitor: Its Mechanism of Action and Antiviral Activity in the Replicon System
Agnieszka Gozdek, Igor Zhukov, Agnieszka Polkowska, Jaroslaw Poznanski, Anna Stankiewicz-Drogon, Jerzy M. Pawlowicz, Wlodzimierz Zagórski-Ostoja, Peter Borowski, and Anna M. Boguszewska-Chachulska
Antimicrob. Agents Chemother. February 2008 52: 393-401; published ahead of print November 26, 2007, doi:10.1128/AAC.00961-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

The Mechanism of Action of β-D-2'-Deoxy-2'-Fluoro-2'-C-Methylcytidine Involves a Second Metabolic Pathway Leading to β-D-2'-Deoxy-2'-Fluoro-2'-C-Methyluridine 5'-Triphosphate, a Potent Inhibitor of the Hepatitis C Virus RNA-Dependent RNA Polymerase
Eisuke Murakami, Congrong Niu, Haiying Bao, Holly M. Micolochick Steuer, Tony Whitaker, Tammy Nachman, Michael A. Sofia, Peiyuan Wang, Michael J. Otto, and Phillip A. Furman
Antimicrob. Agents Chemother. February 2008 52: 458-464; published ahead of print November 12, 2007, doi:10.1128/AAC.01184-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Effect of Resiquimod 0.01% Gel on Lesion Healing and Viral Shedding When Applied to Genital Herpes Lesions
Kenneth H. Fife, Tze-Chiang Meng, Daron G. Ferris, and Ping Liu
Antimicrob. Agents Chemother. February 2008 52: 477-482; published ahead of print November 26, 2007, doi:10.1128/AAC.01173-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Factors Associated with the Selection of Mutations Conferring Resistance to Protease Inhibitors (PIs) in PI-Experienced Patients Displaying Treatment Failure on Darunavir
Sidonie Lambert-Niclot, Philippe Flandre, Ana Canestri, Gilles Peytavin, Christine Blanc, Rachid Agher, Cathia Soulié, Marc Wirden, Christine Katlama, Vincent Calvez, and Anne-Geneviève Marcelin
Antimicrob. Agents Chemother. February 2008 52: 491-496; published ahead of print November 26, 2007, doi:10.1128/AAC.00909-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Deactivation of Human Immunodeficiency Virus Type 1 in Medium by Copper Oxide-Containing Filters
Gadi Borkow, Humberto H. Lara, Chandice Y. Covington, Adeline Nyamathi, and Jeffrey Gabbay
Antimicrob. Agents Chemother. February 2008 52: 518-525; published ahead of print December 10, 2007, doi:10.1128/AAC.00899-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pharmacokinetic Interaction between Fosamprenavir-Ritonavir and Rifabutin in Healthy Subjects
Susan L. Ford, Ya-Chi Chen, Yu Lou, Julie Borland, Sherene S. Min, Geoffrey J. Yuen, and Mark J. Shelton
Antimicrob. Agents Chemother. February 2008 52: 534-538; published ahead of print December 3, 2007, doi:10.1128/AAC.00724-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Cidofovir and (S)-9-[3-Hydroxy-(2-Phosphonomethoxy)Propyl]Adenine Are Highly Effective Inhibitors of Vaccinia Virus DNA Polymerase When Incorporated into the Template Strand
Wendy C. Magee, Kathy A. Aldern, Karl Y. Hostetler, and David H. Evans
Antimicrob. Agents Chemother. February 2008 52: 586-597; published ahead of print December 3, 2007, doi:10.1128/AAC.01172-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Entecavir for Treatment of Hepatitis B Virus Displays No In Vitro Mitochondrial Toxicity or DNA Polymerase Gamma Inhibition
Charles E. Mazzucco, Robert K. Hamatake, Richard J. Colonno, and Daniel J. Tenney
Antimicrob. Agents Chemother. February 2008 52: 598-605; published ahead of print December 3, 2007, doi:10.1128/AAC.01122-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Pharmacokinetics of Antiretroviral Regimens Containing Tenofovir Disoproxil Fumarate and Atazanavir-Ritonavir in Adolescents and Young Adults with Human Immunodeficiency Virus Infection
Jennifer J. Kiser, Courtney V. Fletcher, Patricia M. Flynn, Coleen K. Cunningham, Craig M. Wilson, Bill G. Kapogiannis, Hanna Major-Wilson, Rolando M. Viani, Nancy X. Liu, Larry R. Muenz, D. Robert Harris, Peter L. Havens and the Adolescent Trials Network for HIV/AIDS Interventions
Antimicrob. Agents Chemother. February 2008 52: 631-637; published ahead of print November 19, 2007, doi:10.1128/AAC.00761-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Intracellular Metabolism of the Nucleotide Prodrug GS-9131, a Potent Anti-Human Immunodeficiency Virus Agent
Adrian S. Ray, Jennifer E. Vela, Constantine G. Boojamra, Lijun Zhang, Hon Hui, Christian Callebaut, Kirsten Stray, Kuei-Ying Lin, Ying Gao, Richard L. Mackman, and Tomas Cihlar
Antimicrob. Agents Chemother. February 2008 52: 648-654; published ahead of print December 3, 2007, doi:10.1128/AAC.01209-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Design and Profiling of GS-9148, a Novel Nucleotide Analog Active against Nucleoside-Resistant Variants of Human Immunodeficiency Virus Type 1, and Its Orally Bioavailable Phosphonoamidate Prodrug, GS-9131
Tomas Cihlar, Adrian S. Ray, Constantine G. Boojamra, Lijun Zhang, Hon Hui, Genevieve Laflamme, Jennifer E. Vela, Deborah Grant, James Chen, Florence Myrick, Kirsten L. White, Ying Gao, Kuei-Ying Lin, Janet L. Douglas, Neil T. Parkin, Anne Carey, Rowchanak Pakdaman, and Richard L. Mackman
Antimicrob. Agents Chemother. February 2008 52: 655-665; published ahead of print December 3, 2007, doi:10.1128/AAC.01215-07
[Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]

Novel Chimeric Genotype 1b/2a Hepatitis C Virus Suitable for High-Throughput Screening
Yingjia Zhang, Peter Weady, Rohit Duggal, and Weidong Hao
Antimicrob. Agents Chemother. February 2008 52: 666-674; published ahead of print November 26, 2007, doi:10.1128/AAC.01133-07
[Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]

In Vitro Resistance Study of AG-021541, a Novel Nonnucleoside Inhibitor of the Hepatitis C Virus RNA-Dependent RNA Polymerase
Stephanie T. Shi, Koleen J. Herlihy, Joanne P. Graham, Shella A. Fuhrman, Chau Doan, Hans Parge, Michael Hickey, Jingjin Gao, Xiu Yu, Fannie Chau, Javier Gonzalez, Hui Li, Cristina Lewis, Amy K. Patick, and Rohit Duggal
Antimicrob. Agents Chemother. February 2008 52: 675-683; published ahead of print December 10, 2007, doi:10.1128/AAC.00834-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Intracellular Efavirenz Levels in Peripheral Blood Mononuclear Cells from Human Immunodeficiency Virus-Infected Individuals
Rie Tanaka, Hideji Hanabusa, Ei Kinai, Naoki Hasegawa, Masayoshi Negishi, and Shingo Kato
Antimicrob. Agents Chemother. February 2008 52: 782-785; published ahead of print December 10, 2007, doi:10.1128/AAC.01613-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mechanisms of Action:

Azurin-Like Protein Blocks Invasion of Toxoplasma gondii through Potential Interactions with Parasite Surface Antigen SAG1
Arunasalam Naguleswaran, Arsenio M. Fialho, Anita Chaudhari, Chang Soo Hong, Ananda M. Chakrabarty, and William J. Sullivan, Jr.
Antimicrob. Agents Chemother. February 2008 52: 402-408; published ahead of print December 10, 2007, doi:10.1128/AAC.01005-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Human Pre-Elafin Inhibits a Pseudomonas aeruginosa-Secreted Peptidase and Prevents Its Proliferation in Complex Media
Audrey Bellemare, Nathalie Vernoux, Dany Morisset, and Yves Bourbonnais
Antimicrob. Agents Chemother. February 2008 52: 483-490; published ahead of print November 19, 2007, doi:10.1128/AAC.00585-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

The P-113 Fragment of Histatin 5 Requires a Specific Peptide Sequence for Intracellular Translocation in Candida albicans, Which Is Independent of Cell Wall Binding
Woong Sik Jang, Xuewei Serene Li, Jianing N. Sun, and Mira Edgerton
Antimicrob. Agents Chemother. February 2008 52: 497-504; published ahead of print November 12, 2007, doi:10.1128/AAC.01199-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Modulation of Gene Expression in Human Macrophages Treated with the Anti-Leishmania Pentavalent Antimonial Drug Sodium Stibogluconate
Karima El Fadili, Michaël Imbeault, Nadine Messier, Gaétan Roy, Benjamin Gourbal, Marc Bergeron, Michel J. Tremblay, Danielle Légaré, and Marc Ouellette
Antimicrob. Agents Chemother. February 2008 52: 526-533; published ahead of print December 10, 2007, doi:10.1128/AAC.01183-07
[Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]

Molecular Mechanism of Target Recognition by Subtilin, a Class I Lanthionine Antibiotic
Judicaël Parisot, Sarah Carey, Eefjan Breukink, Weng C. Chan, Arjan Narbad, and Boyan Bonev
Antimicrob. Agents Chemother. February 2008 52: 612-618; published ahead of print November 12, 2007, doi:10.1128/AAC.00836-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mefloquine-Induced Disruption of Calcium Homeostasis in Mammalian Cells Is Similar to That Induced by Ionomycin
D. Caridha, D. Yourick, M. Cabezas, L. Wolf, T. H. Hudson, and G. S. Dow
Antimicrob. Agents Chemother. February 2008 52: 684-693; published ahead of print November 12, 2007, doi:10.1128/AAC.00874-07
[Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]

Antiplasmodial Activity of [(Aryl)arylsulfanylmethyl]Pyridine
Sanjay Kumar, Sajal Kumar Das, Sumanta Dey, Pallab Maity, Mithu Guha, Vinay Choubey, Gautam Panda, and Uday Bandyopadhyay
Antimicrob. Agents Chemother. February 2008 52: 705-715; published ahead of print November 19, 2007, doi:10.1128/AAC.00898-07
[Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]

Zygomycetes Hyphae Trigger an Early, Robust Proinflammatory Response in Human Polymorphonuclear Neutrophils through Toll-Like Receptor 2 Induction but Display Relative Resistance to Oxidative Damage
G. Chamilos, R. E. Lewis, G. Lamaris, T. J. Walsh, and D. P. Kontoyiannis
Antimicrob. Agents Chemother. February 2008 52: 722-724; published ahead of print November 19, 2007, doi:10.1128/AAC.01136-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Telithromycin and Quinupristin-Dalfopristin Induce Delayed Death in Plasmodium falciparum
Diana Barthel, Martin Schlitzer, and Gabriele Pradel
Antimicrob. Agents Chemother. February 2008 52: 774-777; published ahead of print December 3, 2007, doi:10.1128/AAC.00892-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Susceptibility:

In Vitro Interactions between Tacrolimus and Azoles against Candida albicans Determined by Different Methods
Shujuan Sun, Yan Li, Qiongjie Guo, Changwen Shi, Jinlong Yu, and Lin Ma
Antimicrob. Agents Chemother. February 2008 52: 409-417; published ahead of print December 3, 2007, doi:10.1128/AAC.01070-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Thiopurine Drugs Azathioprine and 6-Mercaptopurine Inhibit Mycobacterium paratuberculosis Growth In Vitro
Sung Jae Shin and Michael T. Collins
Antimicrob. Agents Chemother. February 2008 52: 418-426; published ahead of print December 10, 2007, doi:10.1128/AAC.00678-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Cytotoxic Activity of N-Chlorotaurine on Acanthamoeba spp.
Ursula Fürnkranz, Markus Nagl, Waldemar Gottardi, Martina Köhsler, Horst Aspöck, and Julia Walochnik
Antimicrob. Agents Chemother. February 2008 52: 470-476; published ahead of print November 26, 2007, doi:10.1128/AAC.00715-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

A Sphingolipid Inhibitor Induces a Cytokinesis Arrest and Blocks Stage Differentiation in Giardia lamblia
Sabrina Sonda, Sasa Stefanic, and Adrian B. Hehl
Antimicrob. Agents Chemother. February 2008 52: 563-569; published ahead of print December 17, 2007, doi:10.1128/AAC.01105-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Antimycobacterial Activities of Capuramycin Analogues
Venkata M. Reddy, Leo Einck, and Carol A. Nacy
Antimicrob. Agents Chemother. February 2008 52: 719-721; published ahead of print December 10, 2007, doi:10.1128/AAC.01469-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Antifungal Susceptibilities of Five Species of Sporothrix
Rita Marimon, Carolina Serena, Josepa Gené, Josep Cano, and Josep Guarro
Antimicrob. Agents Chemother. February 2008 52: 732-734; published ahead of print November 26, 2007, doi:10.1128/AAC.01012-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Inhibitory Activities of 11 Antimicrobial Agents and Bactericidal Activities of Vancomycin and Daptomycin against Invasive Methicillin-Resistant Staphylococcus aureus Isolates Obtained from 1999 through 2006
Robert L. Holmes and James H. Jorgensen
Antimicrob. Agents Chemother. February 2008 52: 757-760; published ahead of print November 26, 2007, doi:10.1128/AAC.00945-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activities of Doripenem and Six Comparator Drugs against 423 Aerobic and Anaerobic Bacterial Isolates from Infected Diabetic Foot Wounds
Ellie J. C. Goldstein, Diane M. Citron, C. Vreni Merriam, Yumi A. Warren, Kerin L. Tyrrell, and Helen T. Fernandez
Antimicrob. Agents Chemother. February 2008 52: 761-766; published ahead of print December 10, 2007, doi:10.1128/AAC.01128-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vitro Activities of Voriconazole, Itraconazole, and Terbinafine Alone or in Combination against Pythium insidiosum Isolates from Brazil
Juliana S. Argenta, Janio M. Santurio, Sydney H. Alves, Daniela I. B. Pereira, Ayrton S. Cavalheiro, Andréia Spanamberg, and Laerte Ferreiro
Antimicrob. Agents Chemother. February 2008 52: 767-769; published ahead of print December 3, 2007, doi:10.1128/AAC.01075-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Comparative In Vitro Activities of Caspofungin and Micafungin, Determined Using the Method of the European Committee on Antimicrobial Susceptibility Testing, against Yeast Isolates Obtained in France in 2005-2006
E. Dannaoui, O. Lortholary, D. Raoux, M. E. Bougnoux, G. Galeazzi, C. Lawrence, D. Moissenet, I. Poilane, D. Hoinard, F. Dromer and the YEASTS Group
Antimicrob. Agents Chemother. February 2008 52: 778-781; published ahead of print December 10, 2007, doi:10.1128/AAC.01140-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Experimental Therapeutics:

Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics
Sreedhar Subramanian, Carol L. Roberts, C. Anthony Hart, Helen M. Martin, Steve W. Edwards, Jonathan M. Rhodes, and Barry J. Campbell
Antimicrob. Agents Chemother. February 2008 52: 427-434; published ahead of print December 10, 2007, doi:10.1128/AAC.00375-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Posaconazole Activity against Candida glabrata after Exposure to Caspofungin or Amphotericin B
Elisabetta Spreghini, Carmelo Massimo Maida, Maria Eleonora Milici, Giorgio Scalise, and Francesco Barchiesi
Antimicrob. Agents Chemother. February 2008 52: 513-517; published ahead of print December 3, 2007, doi:10.1128/AAC.01447-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

In Vivo Pharmacodynamic Characterization of Anidulafungin in a Neutropenic Murine Candidiasis Model
D. Andes, D. J. Diekema, M. A. Pfaller, R. A. Prince, K. Marchillo, J. Ashbeck, and J. Hou
Antimicrob. Agents Chemother. February 2008 52: 539-550; published ahead of print December 10, 2007, doi:10.1128/AAC.01061-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Mechanisms of Resistance:

Telithromycin Resistance in Streptococcus pneumoniae Is Conferred by a Deletion in the Leader Sequence of erm(B) That Increases rRNA Methylation
Nicole Wolter, Anthony M. Smith, David J. Farrell, John Blackman Northwood, Stephen Douthwaite, and Keith P. Klugman
Antimicrob. Agents Chemother. February 2008 52: 435-440; published ahead of print December 3, 2007, doi:10.1128/AAC.01074-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Selection of SHV Extended-Spectrum-β-Lactamase-Dependent Cefotaxime and Ceftazidime Resistance in Klebsiella pneumoniae Requires a Plasmid-Borne bla_SHV Gene
David S. Hammond, Tegan Harris, Jan Bell, John Turnidge, and Philip M. Giffard
Antimicrob. Agents Chemother. February 2008 52: 441-445; published ahead of print November 12, 2007, doi:10.1128/AAC.00359-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Vancomycin-Resistant Staphylococcus aureus Isolates Associated with Inc18-Like vanA Plasmids in Michigan
Wenming Zhu, Nancye C. Clark, Linda K. McDougal, Jeffery Hageman, L. Clifford McDonald, and Jean B. Patel
Antimicrob. Agents Chemother. February 2008 52: 452-457; published ahead of print December 3, 2007, doi:10.1128/AAC.00908-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Role of a Sodium-Dependent Symporter Homologue in the Thermosensitivity of β-Lactam Antibiotic Resistance and Cell Wall Composition in Staphylococcus aureus
Krzysztof Sieradzki, Marilyn Chung, and Alexander Tomasz
Antimicrob. Agents Chemother. February 2008 52: 505-512; published ahead of print December 3, 2007, doi:10.1128/AAC.00504-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Genetic and Biochemical Characterization of CAD-1, a Chromosomally Encoded New Class A Penicillinase from Carnobacterium divergens
Djalal Meziane-Cherif, Dominique Decré, E. Arne Høiby, Patrice Courvalin, and Bruno Périchon
Antimicrob. Agents Chemother. February 2008 52: 551-556; published ahead of print December 10, 2007, doi:10.1128/AAC.01145-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

AdeIJK, a Resistance-Nodulation-Cell Division Pump Effluxing Multiple Antibiotics in Acinetobacter baumannii
Laurence Damier-Piolle, Sophie Magnet, Sylvie Brémont, Thierry Lambert, and Patrice Courvalin
Antimicrob. Agents Chemother. February 2008 52: 557-562; published ahead of print December 17, 2007, doi:10.1128/AAC.00732-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Antimicrobial Activities of Tigecycline and Other Broad-Spectrum Antimicrobials Tested against Serine Carbapenemase- and Metallo-β-Lactamase-Producing Enterobacteriaceae: Report from the SENTRY Antimicrobial Surveillance Program
Mariana Castanheira, Hélio S. Sader, Lalitagauri M. Deshpande, Thomas R. Fritsche, and Ronald N. Jones
Antimicrob. Agents Chemother. February 2008 52: 570-573; published ahead of print December 10, 2007, doi:10.1128/AAC.01114-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Complete DNA Sequence and Analysis of the Transferable Multiple-Drug Resistance Plasmids (R Plasmids) from Photobacterium damselae subsp. piscicida Isolates Collected in Japan and the United States
Mi-Jung Kim, Ikuo Hirono, Ken Kurokawa, Takeshi Maki, John Hawke, Hidehiro Kondo, Mudjekeewis D. Santos, and Takashi Aoki
Antimicrob. Agents Chemother. February 2008 52: 606-611; published ahead of print December 10, 2007, doi:10.1128/AAC.01216-07
[Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]

New Genetic Element Carrying the Erythromycin Resistance Determinant erm(TR) in Streptococcus pneumoniae
Romina Camilli, Maria Del Grosso, Francesco Iannelli, and Annalisa Pantosti
Antimicrob. Agents Chemother. February 2008 52: 619-625; published ahead of print December 10, 2007, doi:10.1128/AAC.01081-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Lincomycin Resistance Gene lnu(D) in Streptococcus uberis
Efthymia Petinaki, Véronique Guérin-Faublée, Vianney Pichereau, Corinne Villers, Adeline Achard, Brigitte Malbruny, and Roland Leclercq
Antimicrob. Agents Chemother. February 2008 52: 626-630; published ahead of print December 17, 2007, doi:10.1128/AAC.01126-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Resistance of Porphyromonas gingivalis ATCC 33277 to Direct Killing by Antimicrobial Peptides Is Protease Independent
Gilad Bachrach, Hamutal Altman, Paul E. Kolenbrander, Natalia I. Chalmers, Michal Gabai-Gutner, Amram Mor, Michael Friedman, and Doron Steinberg
Antimicrob. Agents Chemother. February 2008 52: 638-642; published ahead of print December 17, 2007, doi:10.1128/AAC.01271-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Staphylococcus aureus Clinical Isolate with High-Level Methicillin Resistance with an lytH Mutation Caused by IS1182 Insertion
Takaji Fujimura and Kazuhisa Murakami
Antimicrob. Agents Chemother. February 2008 52: 643-647; published ahead of print December 10, 2007, doi:10.1128/AAC.00395-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Multidrug Transporters CaCdr1p and CaMdr1p of Candida albicans Display Different Lipid Specificities: both Ergosterol and Sphingolipids Are Essential for Targeting of CaCdr1p to Membrane Rafts
Ritu Pasrija, Sneh Lata Panwar, and Rajendra Prasad
Antimicrob. Agents Chemother. February 2008 52: 694-704; published ahead of print December 3, 2007, doi:10.1128/AAC.00861-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Prevalence of and Molecular Basis for Tuberculosis Drug Resistance in the Republic of Georgia: Validation of a QIAplex System for Detection of Drug Resistance-Related Mutations
Medea Gegia, Nino Mdivani, Rodrigo E. Mendes, Haijing Li, Maka Akhalaia, Jian Han, George Khechinashvili, and Yi-Wei Tang
Antimicrob. Agents Chemother. February 2008 52: 725-729; published ahead of print December 10, 2007, doi:10.1128/AAC.01124-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Decline in Sulfadoxine-Pyrimethamine-Resistant Alleles after Change in Drug Policy in the Amazon Region of Peru
Zhiyong Zhou, Sean M. Griffing, Alexandre Macedo de Oliveira, Andrea M. McCollum, Wilmer Marquino Quezada, Nancy Arrospide, Ananias A. Escalante, and Venkatachalam Udhayakumar
Antimicrob. Agents Chemother. February 2008 52: 739-741; published ahead of print November 19, 2007, doi:10.1128/AAC.00975-07
[Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]

Tetracycline Resistance in Ureaplasma spp. and Mycoplasma hominis: Prevalence in Bordeaux, France, from 1999 to 2002 and Description of Two tet(M)-Positive Isolates of M. hominis Susceptible to Tetracyclines
S. Dégrange, H. Renaudin, A. Charron, C. Bébéar, and C. M. Bébéar
Antimicrob. Agents Chemother. February 2008 52: 742-744; published ahead of print November 19, 2007, doi:10.1128/AAC.00960-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Are All the DNA Gyrase Mutations Found in Mycobacterium leprae Clinical Strains Involved in Resistance to Fluoroquinolones?
Stéphanie Matrat, Emmanuelle Cambau, Vincent Jarlier, and Alexandra Aubry
Antimicrob. Agents Chemother. February 2008 52: 745-747; published ahead of print December 10, 2007, doi:10.1128/AAC.01095-07
[Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]

In Vitro Capability of Faropenem To Select for Resistant Mutants of Streptococcus pneumoniae and Haemophilus influenzae
Klaudia Kosowska-Shick, Catherine Clark, Kim Credito, Bonifacio Dewasse, Linda Beachel, Lois Ednie, and Peter C. Appelbaum
Antimicrob. Agents Chemother. February 2008 52: 748-752; published ahead of print December 17, 2007, doi:10.1128/AAC.01389-07
[Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]

Combined Real-Time PCR and Pyrosequencing Strategy for Objective, Sensitive, Specific, and High-Throughput Identification of Reduced Susceptibility to Penicillins in Neisseria meningitidis
Sara Thulin, Per Olcén, Hans Fredlund, and Magnus Unemo
Antimicrob. Agents Chemother. February 2008 52: 753-756; published ahead of print December 10, 2007, doi:10.1128/AAC.00914-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Tetracycline Resistance Gene tet(W) in the Pathogenic Bacterium Clostridium difficile
Patrizia Spigaglia, Fabrizio Barbanti, and Paola Mastrantonio
Antimicrob. Agents Chemother. February 2008 52: 770-773; published ahead of print December 10, 2007, doi:10.1128/AAC.00957-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Nationwide Study of the Prevalence, Characteristics, and Molecular Epidemiology of Extended-Spectrum-β-Lactamase-Producing Enterobacteriaceae in France
Muriel Galas, Jean-Winoc Decousser, Nelly Breton, Thierry Godard, Pierre Yves Allouch, Patrick Pina and the Collège de Bactériologie Virologie Hygiène (ColBVH) Study Group
Antimicrob. Agents Chemother. February 2008 52: 786-789; published ahead of print November 19, 2007, doi:10.1128/AAC.00906-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Analysis of the β-Tubulin Gene from Vittaforma corneae Suggests Benzimidazole Resistance
Caspar Franzen and Bernd Salzberger
Antimicrob. Agents Chemother. February 2008 52: 790-793; published ahead of print December 3, 2007, doi:10.1128/AAC.00928-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Clinical Therapeutics:

Interrupted Time Series Analysis of Vancomycin Compared to Cefuroxime for Surgical Prophylaxis in Patients Undergoing Cardiac Surgery
K. W. Garey, D. Lai, T. K. Dao-Tran, L. O. Gentry, L. Y. Hwang, and B. R. Davis
Antimicrob. Agents Chemother. February 2008 52: 446-451; published ahead of print November 19, 2007, doi:10.1128/AAC.00495-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Acquisition of Rectal Colonization by Vancomycin-Resistant Enterococcus among Intensive Care Unit Patients Treated with Piperacillin-Tazobactam versus Those Receiving Cefepime-Containing Antibiotic Regimens
David L. Paterson, Carlene A. Muto, Magdaline Ndirangu, Peter K. Linden, Brian A. Potoski, Blair Capitano, Robert A. Bonomo, David C. Aron, and Curtis J. Donskey
Antimicrob. Agents Chemother. February 2008 52: 465-469; published ahead of print November 19, 2007, doi:10.1128/AAC.01316-06
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Calcineurin Inhibitor Agents Interact Synergistically with Antifungal Agents In Vitro against Cryptococcus neoformans Isolates: Correlation with Outcome in Solid Organ Transplant Recipients with Cryptococcosis
Dimitrios P. Kontoyiannis, Russell E. Lewis, Barbara D. Alexander, Olivier Lortholary, Françoise Dromer, Krishan L. Gupta, George T. John, Ramon del Busto, Goran B. Klintmalm, Jyoti Somani, G. Marshall Lyon, Kenneth Pursell, Valentina Stosor, Patricia Munoz, Ajit P. Limaye, Andre C. Kalil, Timothy L. Pruett, Julia Garcia-Diaz, Atul Humar, Sally Houston, Andrew A. House, Dannah Wray, Susan Orloff, Lorraine A. Dowdy, Robert A. Fisher, Joseph Heitman, Nathaniel D. Albert, Marilyn M. Wagener, and Nina Singh
Antimicrob. Agents Chemother. February 2008 52: 735-738; published ahead of print December 10, 2007, doi:10.1128/AAC.00990-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Chemistry; Biosynthesis:

Biosynthetic Investigations of Lactonamycin and Lactonamycin Z: Cloning of the Biosynthetic Gene Clusters and Discovery of an Unusual Starter Unit
Xiujun Zhang, Lawrence B. Alemany, Hans-Peter Fiedler, Michael Goodfellow, and Ronald J. Parry
Antimicrob. Agents Chemother. February 2008 52: 574-585; published ahead of print December 10, 2007, doi:10.1128/AAC.00717-07
[Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]

Biologic Response Modifiers:

Intranasal Granulocyte-Macrophage Colony-Stimulating Factor Reduces the Aspergillus Burden in an Immunosuppressed Murine Model of Pulmonary Aspergillosis
Gerardo Quezada, Nadezhda V. Koshkina, Patrick Zweidler-McKay, Zichao Zhou, Dimitrios P. Kontoyiannis, and Eugenie S. Kleinerman
Antimicrob. Agents Chemother. February 2008 52: 716-718; published ahead of print November 5, 2007, doi:10.1128/AAC.00760-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Analytical Procedures:

Effect of Calcineurin Inhibitors on Posaconazole Blood Levels as Measured by the MVista Microbiological Assay
David Zhuang, Melinda Smedema, Ann LeMonte, Benita K. Book, Mark D. Pescovitz, and L. Joseph Wheat
Antimicrob. Agents Chemother. February 2008 52: 730-731; published ahead of print November 19, 2007, doi:10.1128/AAC.01096-07
[Abstract] [Full Text] [PDF] [Reprints and Permissions]

Letters:

RmtC 16S rRNA Methyltransferase in Australia
Zhiyong Zong, Sally R. Partridge, and Jonathan R. Iredell
Antimicrob. Agents Chemother. February 2008 52: 794-795; published ahead of print November 19, 2007, doi:10.1128/AAC.01399-07
[Full Text] [PDF] [Reprints and Permissions]

Plasmid-Mediated Carbapenem-Hydrolyzing β-Lactamase KPC-2 in Klebsiella pneumoniae Isolate from Greece
Gaelle Cuzon, Thierry Naas, Marie Claude Demachy, and Patrice Nordmann
Antimicrob. Agents Chemother. February 2008 52: 796-797; published ahead of print December 3, 2007, doi:10.1128/AAC.01180-07
[Full Text] [PDF] [Reprints and Permissions]

Carbapenem-Resistant Isolates of Klebsiella pneumoniae in China and Detection of a Conjugative Plasmid (bla_KPC-2 plus qnrB4) and a bla_IMP-4 Gene
Rodrigo E. Mendes, Jan M. Bell, John D. Turnidge, Qiwen Yang, Yunsong Yu, Ziyong Sun, and Ronald N. Jones
Antimicrob. Agents Chemother. February 2008 52: 798-799; published ahead of print December 17, 2007, doi:10.1128/AAC.01185-07
[Full Text] [PDF] [Reprints and Permissions]

In Vitro-Selected Linezolid-Resistant Mycobacterium tuberculosis Mutants
Doris Hillemann, Sabine Rüsch-Gerdes, and Elvira Richter
Antimicrob. Agents Chemother. February 2008 52: 800-801; published ahead of print December 10, 2007, doi:10.1128/AAC.01189-07
[Full Text] [PDF] [Reprints and Permissions]

In Vitro Activity of Cefpodoxime, an Expanded-Spectrum Cephalosporin, against Salmonella enterica Serotype Typhi
Bhaswati Sen, Manjira Bhattacharya, and Swapan K. Niyogi
Antimicrob. Agents Chemother. February 2008 52: 802-803; published ahead of print November 26, 2007, doi:10.1128/AAC.00867-07
[Full Text] [PDF] [Reprints and Permissions]

Community-Acquired Liver Abscess Caused by Serotype K1 Klebsiella pneumoniae with CTX-M-15-Type Extended-Spectrum β-Lactamase
Sheng-Chiang Su, L. K. Siu, Ling Ma, Kuo-Ming Yeh, Chang-Phone Fung, Jung-Chung Lin, and Feng-Yee Chang
Antimicrob. Agents Chemother. February 2008 52: 804-805; published ahead of print December 3, 2007, doi:10.1128/AAC.01269-07
[Full Text] [PDF] [Reprints and Permissions]

Ciprofloxacin-Resistant Enterobacteria Harboring the aac(6')-Ib-cr Variant Isolated from Feces of Inpatients in an Intensive Care Unit in Uruguay
Nicolás F. Cordeiro, Luciana Robino, Julio Medina, Verónica Seija, Inés Bado, Virginia García, Maximiliano Berro, Julio Pontet, Lucía López, Cristina Bazet, Gloria Rieppi, Gabriel Gutkind, Juan A. Ayala, and Rafael Vignoli
Antimicrob. Agents Chemother. February 2008 52: 806-807; published ahead of print November 12, 2007, doi:10.1128/AAC.00444-07
[Full Text] [PDF] [Reprints and Permissions]

Author's Correction:

Population Pharmacokinetics of Tenofovir in Human Immunodeficiency Virus-Infected Patients Taking Highly Active Antiretroviral Therapy
Vincent Jullien, Jean-Marc Tréluyer, Elisabeth Rey, Patrick Jaffray, Anne Krivine, Laurence Moachon, Agnès Lillo-Le Louet, Anne Lescoat, Nicolas Dupin, Dominique Salmon, Gérard Pons, and Saïk Urien
Antimicrob. Agents Chemother. February 2008 52: 808
[Full Text] [PDF] [Reprints and Permissions]

Novel Carbapenem-Hydrolyzing β-Lactamase, KPC-1, from a Carbapenem-Resistant Strain of Klebsiella pneumoniae
Hesna Yigit, Anne Marie Queenan, Gregory J. Anderson, Antonio Domenech-Sanchez, James W. Biddle, Christine D. Steward, Sebastian Alberti, Karen Bush, and Fred C. Tenover
Antimicrob. Agents Chemother. February 2008 52: 809
[Full Text] [PDF] [Reprints and Permissions]

First Report of the Emergence of CTX-M-Type Extended-Spectrum β-Lactamases (ESBLs) as the Predominant ESBL Isolated in a U.S. Health Care System
James S. Lewis, II, Monica Herrera, Brian Wickes, Jan E. Patterson, and James H. Jorgensen
Antimicrob. Agents Chemother. February 2008 52: 810
[Full Text] [PDF] [Reprints and Permissions]

Predictive Genotypic Algorithm for Virologic Response to Lopinavir-Ritonavir in Protease Inhibitor-Experienced Patients
Martin S. King, Richard Rode, Isabelle Cohen-Codar, Vincent Calvez, Anne-Geneviève Marcelin, George J. Hanna, and Dale J. Kempf
Antimicrob. Agents Chemother. February 2008 52: 811
[Full Text] [PDF] [Reprints and Permissions]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.