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Guest Commentary:

George Jacoby, Vincent Cattoir, David Hooper, Luis Martínez-Martínez, Patrice Nordmann, Alvaro Pascual, Laurent Poirel, and Minggui Wang

qnr Gene Nomenclature
Antimicrob. Agents Chemother. 2008 52: 2297-2299. [Full Text] [PDF] [Reprints and Permissions]  

Pharmacology:

Thomas P. Lodise, Jr., Mark Gotfried, Steven Barriere, and George L. Drusano

Telavancin Penetration into Human Epithelial Lining Fluid Determined by Population Pharmacokinetic Modeling and Monte Carlo Simulation
Antimicrob. Agents Chemother. 2008 52: 2300-2304. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Navita L. Mallalieu, Siân Lennon, Mei Liu, Christopher Kirkpatrick, Richard Robson, Eric Luedin, and Brian E. Davies

Effect of Impaired Renal Function on the Pharmacokinetics of Tomopenem (RO4908463/CS-023), a Novel Carbapenem
Antimicrob. Agents Chemother. 2008 52: 2360-2366. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Aryun Kim, Mary Anne Banevicius, and David P. Nicolau

In Vivo Pharmacodynamic Profiling of Doripenem against Pseudomonas aeruginosa by Simulating Human Exposures
Antimicrob. Agents Chemother. 2008 52: 2497-2502. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Bharat Damle, Martin Stogniew, and James Dowell

Pharmacokinetics and Tissue Distribution of Anidulafungin in Rats
Antimicrob. Agents Chemother. 2008 52: 2673-2676. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Resistance:

Guillermo Garcia-Effron, Santosh K. Katiyar, Steven Park, Thomas D. Edlind, and David S. Perlin

A Naturally Occurring Proline-to-Alanine Amino Acid Change in Fks1p in Candida parapsilosis, Candida orthopsilosis, and Candida metapsilosis Accounts for Reduced Echinocandin Susceptibility
Antimicrob. Agents Chemother. 2008 52: 2305-2312. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Joanna E. Mroczkowska and Miriam Barlow

Fitness Trade-Offs in bla_TEM Evolution
Antimicrob. Agents Chemother. 2008 52: 2340-2345. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Godfrey Lisk, Margaret Pain, Ilya Y. Gluzman, Shivkumar Kambhampati, Tetsuya Furuya, Xin-zhuan Su, Michael P. Fay, Daniel E. Goldberg, and Sanjay A. Desai

Changes in the Plasmodial Surface Anion Channel Reduce Leupeptin Uptake and Can Confer Drug Resistance in Plasmodium falciparum-Infected Erythrocytes
Antimicrob. Agents Chemother. 2008 52: 2346-2354. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ângela Novais, Rafael Cantón, Teresa M. Coque, Andrés Moya, Fernando Baquero, and Juan Carlos Galán

Mutational Events in Cefotaximase Extended-Spectrum β-Lactamases of the CTX-M-1 Cluster Involved in Ceftazidime Resistance
Antimicrob. Agents Chemother. 2008 52: 2377-2382. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Yousef M. Abouzeed, Sylvie Baucheron, and Axel Cloeckaert

ramR Mutations Involved in Efflux-Mediated Multidrug Resistance in Salmonella enterica Serovar Typhimurium
Antimicrob. Agents Chemother. 2008 52: 2428-2434. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Joanna Empel, Anna Baraniak, Elzbieta Literacka, Agnieszka Mrówka, Janusz Fiett, Ewa Sadowy, Waleria Hryniewicz, Marek Gniadkowski and the Beta-PL Study Group

Molecular Survey of β-Lactamases Conferring Resistance to Newer β-Lactams in Enterobacteriaceae Isolates from Polish Hospitals
Antimicrob. Agents Chemother. 2008 52: 2449-2454. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Katy Jeannot, Sylvie Elsen, Thilo Köhler, Ina Attree, Christian van Delden, and Patrick Plésiat

Resistance and Virulence of Pseudomonas aeruginosa Clinical Strains Overproducing the MexCD-OprJ Efflux Pump
Antimicrob. Agents Chemother. 2008 52: 2455-2462. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Magdalena Stoczko, Jean-Marie Frère, Gian Maria Rossolini, and Jean-Denis Docquier

Functional Diversity among Metallo-β-Lactamases: Characterization of the CAR-1 Enzyme of Erwinia carotovora
Antimicrob. Agents Chemother. 2008 52: 2473-2479. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Olga Danilchanka, Claudia Mailaender, and Michael Niederweis

Identification of a Novel Multidrug Efflux Pump of Mycobacterium tuberculosis
Antimicrob. Agents Chemother. 2008 52: 2503-2511. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Renee S. Levings, Steven P. Djordjevic, and Ruth M. Hall

SGI2, a Relative of Salmonella Genomic Island SGI1 with an Independent Origin
Antimicrob. Agents Chemother. 2008 52: 2529-2537. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Te-Li Chen, Roy Chen-Chih Wu, Men-Fang Shaio, Chang-Phone Fung, and Wen-Long Cho

Acquisition of a Plasmid-Borne bla_OXA-58 Gene with an Upstream IS1008 Insertion Conferring a High Level of Carbapenem Resistance to Acinetobacter baumannii
Antimicrob. Agents Chemother. 2008 52: 2573-2580. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Bruno Périchon, Pierre Bogaerts, Thierry Lambert, Lionel Frangeul, Patrice Courvalin, and Marc Galimand

Sequence of Conjugative Plasmid pIP1206 Mediating Resistance to Aminoglycosides by 16S rRNA Methylation and to Hydrophilic Fluoroquinolones by Efflux
Antimicrob. Agents Chemother. 2008 52: 2581-2592. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Michele Iacono, Laura Villa, Daniela Fortini, Roberta Bordoni, Francesco Imperi, Raoul J. P. Bonnal, Thomas Sicheritz-Ponten, Gianluca De Bellis, Paolo Visca, Antonio Cassone, and Alessandra Carattoli

Whole-Genome Pyrosequencing of an Epidemic Multidrug-Resistant Acinetobacter baumannii Strain Belonging to the European Clone II Group
Antimicrob. Agents Chemother. 2008 52: 2616-2625. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Marjo Haanperä, Sofia D. Forssten, Pentti Huovinen, and Jari Jalava

Typing of SHV Extended-Spectrum β-Lactamases by Pyrosequencing in Klebsiella pneumoniae Strains with Chromosomal SHV β-Lactamase
Antimicrob. Agents Chemother. 2008 52: 2632-2635. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mallika Imwong, Sasithon Pukrittayakamee, Wirichada Pongtavornpinyo, Supatchara Nakeesathit, Shalini Nair, Paul Newton, Francois Nosten, Timothy J. C. Anderson, Arjen Dondorp, Nicholas P. J. Day, and Nicholas J. White

Gene Amplification of the Multidrug Resistance 1 Gene of Plasmodium vivax Isolates from Thailand, Laos, and Myanmar
Antimicrob. Agents Chemother. 2008 52: 2657-2659. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

David A. Boyd, Barbara M. Willey, Darlene Fawcett, Nazira Gillani, and Michael R. Mulvey

Molecular Characterization of Enterococcus faecalis N06-0364 with Low-Level Vancomycin Resistance Harboring a Novel D-Ala-D-Ser Gene Cluster, vanL
Antimicrob. Agents Chemother. 2008 52: 2667-2672. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Andrea Endimiani, Lenore L. Carias, Andrea M. Hujer, Christopher R. Bethel, Kristine M. Hujer, Federico Perez, Rebecca A. Hutton, William R. Fox, Geraldine S. Hall, Michael R. Jacobs, David L. Paterson, Louis B. Rice, Stephen G. Jenkins, Fred C. Tenover, and Robert A. Bonomo

Presence of Plasmid-Mediated Quinolone Resistance in Klebsiella pneumoniae Isolates Possessing bla_KPC in the United States
Antimicrob. Agents Chemother. 2008 52: 2680-2682. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

J. M. Sierra, D. Rodriguez-Puig, A. Soriano, J. Mensa, C. Piera, and J. Vila

Accumulation of ^99mTc-Ciprofloxacin in Staphylococcus aureus and Pseudomonas aeruginosa
Antimicrob. Agents Chemother. 2008 52: 2691-2692. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mechanisms of Action:

Gregory T. Robertson, Eric J. Bonventre, Timothy B. Doyle, Qun Du, Leonard Duncan, Timothy W. Morris, Eric D. Roche, Dalai Yan, and A. Simon Lynch

In Vitro Evaluation of CBR-2092, a Novel Rifamycin-Quinolone Hybrid Antibiotic: Studies of the Mode of Action in Staphylococcus aureus
Antimicrob. Agents Chemother. 2008 52: 2313-2323. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Helena M. Linge, Mattias Collin, Pontus Nordenfelt, Matthias Mörgelin, Martin Malmsten, and Arne Egesten

The Human CXC Chemokine Granulocyte Chemotactic Protein 2 (GCP-2)/CXCL6 Possesses Membrane-Disrupting Properties and Is Antibacterial
Antimicrob. Agents Chemother. 2008 52: 2599-2607. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Susceptibility:

Gregory T. Robertson, Eric J. Bonventre, Timothy B. Doyle, Qun Du, Leonard Duncan, Timothy W. Morris, Eric D. Roche, Dalai Yan, and A. Simon Lynch

In Vitro Evaluation of CBR-2092, a Novel Rifamycin-Quinolone Hybrid Antibiotic: Microbiology Profiling Studies with Staphylococci and Streptococci
Antimicrob. Agents Chemother. 2008 52: 2324-2334. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Deborah C. Draghi, Bret M. Benton, Kevin M. Krause, Clyde Thornsberry, Chris Pillar, and Daniel F. Sahm

Comparative Surveillance Study of Telavancin Activity against Recently Collected Gram-Positive Clinical Isolates from across the United States
Antimicrob. Agents Chemother. 2008 52: 2383-2388. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Silvia García-Cobos, José Campos, Federico Román, Cristina Carrera, María Pérez-Vázquez, Belén Aracil, and Jesús Oteo

Low β-Lactamase-Negative Ampicillin-Resistant Haemophilus influenzae Strains Are Best Detected by Testing Amoxicillin Susceptibility by the Broth Microdilution Method
Antimicrob. Agents Chemother. 2008 52: 2407-2414. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Valeria P. Sülsen, Fernanda M. Frank, Silvia I. Cazorla, Claudia A. Anesini, Emilio L. Malchiodi, Blanca Freixa, Roser Vila, Liliana V. Muschietti, and Virginia S. Martino

Trypanocidal and Leishmanicidal Activities of Sesquiterpene Lactones from Ambrosia tenuifolia Sprengel (Asteraceae)
Antimicrob. Agents Chemother. 2008 52: 2415-2419. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

U. Lek-Uthai, R. Suwanarusk, R. Ruengweerayut, T. S. Skinner-Adams, F. Nosten, D. L. Gardiner, P. Boonma, K. A. Piera, K. T. Andrews, B. MacHunter, J. S. McCarthy, N. M. Anstey, R. N. Price, and B. Russell

Stronger Activity of Human Immunodeficiency Virus Type 1 Protease Inhibitors against Clinical Isolates of Plasmodium vivax than against Those of P. falciparum
Antimicrob. Agents Chemother. 2008 52: 2435-2441. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Xing-Cong Li, Melissa R. Jacob, Shabana I. Khan, M. Khalid Ashfaq, K. Suresh Babu, Ameeta K. Agarwal, Hala N. ElSohly, Susan P. Manly, and Alice M. Clark

Potent In Vitro Antifungal Activities of Naturally Occurring Acetylenic Acids
Antimicrob. Agents Chemother. 2008 52: 2442-2448. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Juan Luis Rodriguez-Tudela, Laura Alcazar-Fuoli, Emilia Mellado, Ana Alastruey-Izquierdo, Araceli Monzon, and Manuel Cuenca-Estrella

Epidemiological Cutoffs and Cross-Resistance to Azole Drugs in Aspergillus fumigatus
Antimicrob. Agents Chemother. 2008 52: 2468-2472. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Pauliina Kärpänoja, Solja T. Nyberg, Miika Bergman, Tinna Voipio, Pirkko Paakkari, Pentti Huovinen, Hannu Sarkkinen and the Finnish Study Group for Antimicrobial Resistance (FiRe Network)

Connection between Trimethoprim-Sulfamethoxazole Use and Resistance in Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis
Antimicrob. Agents Chemother. 2008 52: 2480-2485. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

A. Louie, H. S. Heine, K. Kim, D. L. Brown, B. VanScoy, W. Liu, M. Kinzig-Schippers, F. Sörgel, and G. L. Drusano

Use of an In Vitro Pharmacodynamic Model To Derive a Linezolid Regimen That Optimizes Bacterial Kill and Prevents Emergence of Resistance in Bacillus anthracis
Antimicrob. Agents Chemother. 2008 52: 2486-2496. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Doron Steinberg, Daniel Moreinos, John Featherstone, Moshe Shemesh, and Osnat Feuerstein

Genetic and Physiological Effects of Noncoherent Visible Light Combined with Hydrogen Peroxide on Streptococcus mutans in Biofilm
Antimicrob. Agents Chemother. 2008 52: 2626-2631. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Susanne Perkhofer, Maria Locher, Manuel Cuenca-Estrella, Reinhard Rüchel, Reinhard Würzner, Manfred P. Dierich, and Cornelia Lass-Flörl

Posaconazole Enhances the Activity of Amphotericin B against Hyphae of Zygomycetes In Vitro
Antimicrob. Agents Chemother. 2008 52: 2636-2638. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ian A. Critchley, Michael R. Jacobs, Steven D. Brown, Maria M. Traczewski, Glenn S. Tillotson, and Nebojsa Janjic

Prevalence of Serotype 19A Streptococcus pneumoniae among Isolates from U.S. Children in 2005-2006 and Activity of Faropenem
Antimicrob. Agents Chemother. 2008 52: 2639-2643. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Kevin M. Krause, Marika Renelli, Stacey Difuntorum, Terry X. Wu, Dmitri V. Debabov, and Bret M. Benton

In Vitro Activity of Telavancin against Resistant Gram-Positive Bacteria
Antimicrob. Agents Chemother. 2008 52: 2647-2652. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Zhengxiang He, Li Qin, Lili Chen, Nanzheng Peng, Jianlan You, and Xiaoping Chen

Synergy of Human Immunodeficiency Virus Protease Inhibitors with Chloroquine against Plasmodium falciparum In Vitro and Plasmodium chabaudi In Vivo
Antimicrob. Agents Chemother. 2008 52: 2653-2656. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ali A. Abdul Sater, David M. Ojcius, and Matthew P. Meyer

Susceptibility of Chlamydia trachomatis to the Excipient Hydroxyethyl Cellulose: pH and Concentration Dependence of Antimicrobial Activity
Antimicrob. Agents Chemother. 2008 52: 2660-2662. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Gregory G. Stone, Dennis Girard, Steve Finegan, Joan Duignan, John Schafer, Meghan Maloney, Richard P. Zaniewski, Steven J. Brickner, Sarah K. Wade, Phuong T. Le, and Michael D. Huband

In Vitro Antibacterial Activity of CE-156811, a Novel Analog Derived from Hygromycin A
Antimicrob. Agents Chemother. 2008 52: 2663-2666. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Chia-Ying Liu, Yu-Tsung Huang, Chun-Hsing Liao, and Po-Ren Hsueh

In Vitro Activities of Tigecycline against Clinical Isolates of Aeromonas, Vibrio, and Salmonella Species in Taiwan
Antimicrob. Agents Chemother. 2008 52: 2677-2679. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Anna Maria Tortorano, Anna Prigitano, Giovanna Dho, Maria Carmela Esposto, Claudia Gianni, Anna Grancini, Cristina Ossi, and Maria Anna Viviani

Species Distribution and In Vitro Antifungal Susceptibility Patterns of 75 Clinical Isolates of Fusarium spp. from Northern Italy
Antimicrob. Agents Chemother. 2008 52: 2683-2685. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Carmen Betriu, Esther Culebras, María Gómez, Fátima López, Iciar Rodríguez-Avial, and Juan J. Picazo

Resistance Trends of the Bacteroides fragilis Group over a 10-Year Period, 1997 to 2006, in Madrid, Spain
Antimicrob. Agents Chemother. 2008 52: 2686-2690. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Experimental Therapeutics:

Kyriaki Kanellakopoulou, George C. Thivaios, Maria Kolia, Ismini Dontas, Lydia Nakopoulou, Eleftherios Dounis, Evangelos J. Giamarellos-Bourboulis, Andreas Andreopoulos, Panayotis Karagiannakos, and Helen Giamarellou

Local Treatment of Experimental Pseudomonas aeruginosa Osteomyelitis with a Biodegradable Dilactide Polymer Releasing Ciprofloxacin
Antimicrob. Agents Chemother. 2008 52: 2335-2339. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Manjunath P. Pai, Marie L. Samples, Renee-Claude Mercier, and Michael N. Spilde

Activities and Ultrastructural Effects of Antifungal Combinations against Simulated Candida Endocardial Vegetations
Antimicrob. Agents Chemother. 2008 52: 2367-2376. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Somvadee Laohavaleeson, Pamela R. Tessier, and David P. Nicolau

Pharmacodynamic Characterization of Ceftobiprole in Experimental Pneumonia Caused by Phenotypically Diverse Staphylococcus aureus Strains
Antimicrob. Agents Chemother. 2008 52: 2389-2394. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Francesc Marco, Cristina García de la Mària, Yolanda Armero, Eurídice Amat, Dolors Soy, Asunción Moreno, Ana del Río, Manel Almela, Carlos A. Mestres, José M. Gatell, María Teresa Jiménez de Anta, José M. Miró for the Hospital Clinic Experimental Endocarditis Study Group

Daptomycin Is Effective in Treatment of Experimental Endocarditis Due to Methicillin-Resistant and Glycopeptide-Intermediate Staphylococcus aureus
Antimicrob. Agents Chemother. 2008 52: 2538-2543. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ana C. Vallor, William R. Kirkpatrick, Laura K. Najvar, Rosie Bocanegra, Marsha C. Kinney, Annette W. Fothergill, Monica L. Herrera, Brian L. Wickes, John R. Graybill, and Thomas F. Patterson

Assessment of Aspergillus fumigatus Burden in Pulmonary Tissue of Guinea Pigs by Quantitative PCR, Galactomannan Enzyme Immunoassay, and Quantitative Culture
Antimicrob. Agents Chemother. 2008 52: 2593-2598. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Antiviral Agents:

Andreas C. W. Jenke, Andreas D. Wilhelm, Valerie Orth, Hans Joachim Lipps, Ulrike Protzer, and Stefan Wirth

Long-Term Suppression of Hepatitis B Virus Replication by Short Hairpin RNA Expression Using the Scaffold/Matrix Attachment Region-Based Replicating Vector System pEPI-1
Antimicrob. Agents Chemother. 2008 52: 2355-2359. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Yoshiko Fukui, Keiko Shindoh, Yumiko Yamamoto, Shin Koyano, Isao Kosugi, Toyofumi Yamaguchi, Ichiro Kurane, and Naoki Inoue

Establishment of a Cell-Based Assay for Screening of Compounds Inhibiting Very Early Events in the Cytomegalovirus Replication Cycle and Characterization of a Compound Identified Using the Assay
Antimicrob. Agents Chemother. 2008 52: 2420-2427. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Edward G. Bridges, Jules R. Selden, and Shouqi Luo

Nonclinical Safety Profile of Telbivudine, a Novel Potent Antiviral Agent for Treatment of Hepatitis B
Antimicrob. Agents Chemother. 2008 52: 2521-2528. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Katty Terrazas-Aranda, Yven Van Herrewege, Daria Hazuda, Paul Lewi, Roberta Costi, Roberto Di Santo, Andrea Cara, and Guido Vanham

Human Immunodeficiency Virus Type 1 (HIV-1) Integration: a Potential Target for Microbicides To Prevent Cell-Free or Cell-Associated HIV-1 Infection
Antimicrob. Agents Chemother. 2008 52: 2544-2554. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Lucie Durand-Gasselin, Alain Pruvost, Axelle Dehée, Genevieve Vaudre, Marie-Dominique Tabone, Jacques Grassi, Guy Leverger, Antoine Garbarg-Chenon, Henri Bénech, and Catherine Dollfus

High Levels of Zidovudine (AZT) and Its Intracellular Phosphate Metabolites in AZT- and AZT-Lamivudine-Treated Newborns of Human Immunodeficiency Virus-Infected Mothers
Antimicrob. Agents Chemother. 2008 52: 2555-2563. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Signe Fransen, Gary Bridger, Jeannette M. Whitcomb, Jonathan Toma, Eric Stawiski, Neil Parkin, Christos J. Petropoulos, and Wei Huang

Suppression of Dualtropic Human Immunodeficiency Virus Type 1 by the CXCR4 Antagonist AMD3100 Is Associated with Efficiency of CXCR4 Use and Baseline Virus Composition
Antimicrob. Agents Chemother. 2008 52: 2608-2615. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Clinical Therapeutics:

Esther Calbo, Montserrat Alsina, Mónica Rodríguez-Carballeira, Josep Lite, and Javier Garau

Systemic Expression of Cytokine Production in Patients with Severe Pneumococcal Pneumonia: Effects of Treatment with a β-Lactam versus a Fluoroquinolone
Antimicrob. Agents Chemother. 2008 52: 2395-2402. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Wafa N. Al-Nassir, Ajay K. Sethi, Yuejin Li, Michael J. Pultz, Michelle M. Riggs, and Curtis J. Donskey

Both Oral Metronidazole and Oral Vancomycin Promote Persistent Overgrowth of Vancomycin-Resistant Enterococci during Treatment of Clostridium difficile-Associated Disease
Antimicrob. Agents Chemother. 2008 52: 2403-2406. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

David J. Riedel, Elizabeth Weekes, and Graeme N. Forrest

Addition of Rifampin to Standard Therapy for Treatment of Native Valve Infective Endocarditis Caused by Staphylococcus aureus
Antimicrob. Agents Chemother. 2008 52: 2463-2467. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

M. E. Pichichero, J. R. Casey, S. L. Block, R. Guttendorf, H. Flanner, D. Markowitz, and S. Clausen

Pharmacodynamic Analysis and Clinical Trial of Amoxicillin Sprinkle Administered Once Daily for 7 Days Compared to Penicillin V Potassium Administered Four Times Daily for 10 Days in the Treatment of Tonsillopharyngitis Due to Streptococcus pyogenes in Children
Antimicrob. Agents Chemother. 2008 52: 2512-2520. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Raul R. Ribeiro, Eliane P. Moura, Vitor M. Pimentel, Weverton M. Sampaio, Sydnei M. Silva, Dante A. Schettini, Cintia F. Alves, Ferdinan A. Melo, Wagner L. Tafuri, Cynthia Demicheli, Maria N. Melo, Frédéric Frézard, and Marilene S. M. Michalick

Reduced Tissue Parasitic Load and Infectivity to Sand Flies in Dogs Naturally Infected by Leishmania (Leishmania) chagasi following Treatment with a Liposome Formulation of Meglumine Antimoniate
Antimicrob. Agents Chemother. 2008 52: 2564-2572. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Biologic Response Modifiers:

Markus Mezger, Iwona Wozniok, Christian Blockhaus, Oliver Kurzai, Holger Hebart, Hermann Einsele, and Juergen Loeffler

Impact of Mycophenolic Acid on the Functionality of Human Polymorphonuclear Neutrophils and Dendritic Cells during Interaction with Aspergillus fumigatus
Antimicrob. Agents Chemother. 2008 52: 2644-2646. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Letters:

Ricardo Dias, David Félix, and Manuela Caniça

Diversity of Penicillin Binding Proteins among Clinical Streptococcus pneumoniae Strains from Portugal
Antimicrob. Agents Chemother. 2008 52: 2693-2695. [Full Text] [PDF] [Reprints and Permissions]  

Stuart B. Levy

Genome Size and Antibiotic Resistance
Antimicrob. Agents Chemother. 2008 52: 2696. [Full Text] [PDF] [Reprints and Permissions]  

Errata:

R. Doug Wagner, Shemedia J. Johnson, and Carl E. Cerniglia

In Vitro Model of Colonization Resistance by the Enteric Microbiota: Effects of Antimicrobial Agents Used in Food-Producing Animals
Antimicrob. Agents Chemother. 2008 52: 2697. [Full Text] [PDF] [Reprints and Permissions]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.