Table of Contents

Articles

• Journal Article

  Pharmacokinetics of michellamine B, a naphthylisoquinoline alkaloid with in vitro activity against human immunodeficiency virus types 1 and 2, in the mouse and dog.

  J G Supko, L Malspeis
• Journal Article

  Effects of macro- and microcirculatory functions on ceftriaxone concentrations in tissues of patients with stage IV peripheral arterial occlusive disease.

  M Hirschl, M Kundi, A M Hirschl, A Georgopoulos
• Clinical Trial | Comparative Study | Journal Article | Randomized Controlled Trial

  Pharmacokinetics and tolerability of single oral doses of 882C87, a potent, new anti-varicella-zoster virus agent, in healthy volunteers.

  R W Peck, B C Weatherley, R Wootton, P Crome, T A Holdich, J Posner
• Comparative Study | Journal Article | Research Support, Non-U.S. Gov't

  Pharmacokinetics of trimethoprim-sulfamethoxazole in critically ill and non-critically ill AIDS patients.

  T W Chin, A Vandenbroucke, I W Fong
• In Vitro | Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  Macromolecular mechanisms of sputum inhibition of tobramycin activity.

  B E Hunt, A Weber, A Berger, B Ramsey, A L Smith
• Clinical Trial | Comparative Study | Journal Article | Multicenter Study | Randomized Controlled Trial | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  Antifungal susceptibility testing of isolates from a randomized, multicenter trial of fluconazole versus amphotericin B as treatment of nonneutropenic patients with candidemia. NIAID Mycoses Study Group and the Candidemia Study Group.

  J H Rex, M A Pfaller, A L Barry, P W Nelson, C D Webb
• Comparative Study | Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  Effects of two antibiotic regimens on course and persistence of experimental Chlamydia pneumoniae TWAR pneumonitis.

  R Malinverni, C C Kuo, L A Campbell, A Lee, J T Grayston
• Journal Article | Research Support, Non-U.S. Gov't

  Long-chain alkanoylcholines, a new category of soft antimicrobial agents that are enzymatically degradable.

  B Ahlström, M Chelminska-Bertilsson, R A Thompson, L Edebo
• Comparative Study | Journal Article | Research Support, Non-U.S. Gov't

  In vivo antiherpesvirus activity of N-7-substituted acyclic nucleoside analog 2-amino-7-[(1,3-dihydroxy-2-propoxy)methyl]purine.

  J Neyts, G Jähne, G Andrei, R Snoeck, I Winkler, E De Clercq
• Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, Non-P.H.S. | Research Support, U.S. Gov't, P.H.S.

  Antimalarial action of hydroxamate-based iron chelators and potentiation of desferrioxamine action by reversed siderophores.

  J Golenser, A Tsafack, Y Amichai, J Libman, A Shanzer, Z I Cabantchik
• Comparative Study | Journal Article | Research Support, Non-U.S. Gov't

  Utilization of time-kill kinetic methodologies for assessing the bactericidal activities of ampicillin and bismuth, alone and in combination, against Helicobacter pylori in stationary and logarithmic growth phases.

  P E Coudron, C W Stratton
• Comparative Study | Journal Article

  Biliary and renal excretions of cefpiramide in Eisai hyperbilirubinemic rats.

  I Muraoka, T Hasegawa, M Nadai, L Wang, S Haghgoo, O Tagaya, T Nabeshima
• Journal Article

  Chemoprophylaxis of Cryptosporidium parvum infection with paromomycin in kids and immunological study.

  R Mancassola, J M Reperant, M Naciri, C Chartier
• Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  Structure-activity and structure-selectivity studies on diaminoquinazolines and other inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase.

  A Rosowsky, J B Hynes, S F Queener
• Comparative Study | Journal Article

  Frequency and mechanism of resistance to antibacterial action of ZM 240401, (6S)-6-fluoro-shikimic acid.

  C D Ewart, D A Jude, J L Thain, W W Nichols
• Clinical Trial | Journal Article | Randomized Controlled Trial

  Comparison of concentrations of two doses of clavulanic acid (200 and 400 milligrams) administered with amoxicillin (2,000 milligrams) in tissues of patients undergoing colorectal surgery.

  C Martin, M N Mallet, B Sastre, X Viviand, A Martin, P De Micco, F Gouin
• Comparative Study | Journal Article

  Intestinal elimination of sparfloxacin, fleroxacin, and ciprofloxacin in rats.

  E Rubinstein, S Dautrey, R Farinoti, L St Julien, J Ramon, C Carbon
• Comparative Study | Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  Point mutations in Staphylococcus aureus PBP 2 gene affect penicillin-binding kinetics and are associated with resistance.

  C J Hackbarth, T Kocagoz, S Kocagoz, H F Chambers
• Journal Article | Research Support, Non-U.S. Gov't

  Nucleotide sequence of the gyrA gene and characterization of ciprofloxacin-resistant mutants of Helicobacter pylori.

  R A Moore, B Beckthold, S Wong, A Kureishi, L E Bryan
• Comparative Study | Journal Article | Research Support, Non-U.S. Gov't

  Sequence identity with type VIII and association with IS176 of type IIIc dihydrofolate reductase from Shigella sonnei.

  N L Barg, S Register, C Thomson, S Amyes
• Journal Article | Research Support, Non-U.S. Gov't

  Transport of 9-(2-phosphonomethoxyethyl)adenine across plasma membrane of HeLa S3 cells is protein mediated.

  T Cihlár, I Rosenberg, I Votruba, A Holý
• Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  Immediate zidovudine treatment protects simian immunodeficiency virus-infected newborn macaques against rapid onset of AIDS.

  K K Van Rompay, M G Otsyula, M L Marthas, C J Miller, M B McChesney, N C Pedersen
• Comparative Study | Journal Article

  Improved efficacy with nonsimultaneous administration of first doses of gentamicin and ceftazidime in vitro.

  M L Barclay, E J Begg, S T Chambers, D R Boswell
• Journal Article | Research Support, Non-U.S. Gov't

  Study of treatment of congenital Toxoplasma gondii infection in rhesus monkeys with pyrimethamine and sulfadiazine.

  E Schoondermark-van de Ven, J Galama, T Vree, W Camps, I Baars, T Eskes, J Meuwissen, W Melchers
• Comparative Study | Journal Article | Research Support, Non-U.S. Gov't

  Single amino acid replacements at positions altered in naturally occurring extended-spectrum TEM beta-lactamases.

  J Blazquez, M I Morosini, M C Negri, M Gonzalez-Leiza, F Baquero
• Journal Article | Research Support, Non-U.S. Gov't

  Modification of immune response in mice by ciprofloxacin.

  M Jimenez-Valera, A Sampedro, E Moreno, A Ruiz-Bravo
• Comparative Study | Journal Article

  Expression of antibiotic resistance genes in the integrated cassettes of integrons.

  C M Collis, R M Hall
• Comparative Study | Journal Article

  Effect of pyrimido[1,6-a]benzimidazoles, quinolones, and Ca2+ on the DNA gyrase-mediated cleavage reaction.

  H Gmünder, K Kuratli, W Keck
• Clinical Trial | Controlled Clinical Trial | Journal Article

  Pharmacokinetics and tolerance of DU-6859a, a new fluoroquinolone, after single and multiple oral doses in healthy volunteers.

  M Nakashima, T Uematsu, K Kosuge, K Umemura, H Hakusui, M Tanaka
• Clinical Trial | Comparative Study | Journal Article | Randomized Controlled Trial | Research Support, Non-U.S. Gov't

  Comparative study of mupirocin and oral co-trimoxazole plus topical fusidic acid in eradication of nasal carriage of methicillin-resistant Staphylococcus aureus.

  F Parras, M C Guerrero, E Bouza, M J Blázquez, S Moreno, M C Menarguez, E Cercenado
• Journal Article | Research Support, Non-U.S. Gov't

  Chloroquine encapsulated in malaria-infected erythrocyte-specific antibody-bearing liposomes effectively controls chloroquine-resistant Plasmodium berghei infections in mice.

  M Owais, G C Varshney, A Choudhury, S Chandra, C M Gupta
• Journal Article | Research Support, Non-U.S. Gov't

  PCR mapping of integrons reveals several novel combinations of resistance genes.

  C Lévesque, L Piché, C Larose, P H Roy
• Comparative Study | Journal Article | Research Support, Non-U.S. Gov't

  Kinetic analysis of extension of substrate specificity with Xanthomonas maltophilia, Aeromonas hydrophila, and Bacillus cereus metallo-beta-lactamases.

  A Felici, G Amicosante
• Comparative Study | Journal Article

  Nikkomycin Z supersensitivity of an echinocandin-resistant mutant of Saccharomyces cerevisiae.

  M el-Sherbeini, J A Clemas
• Comparative Study | Journal Article | Research Support, Non-U.S. Gov't

  Antimicrobial susceptibilities of Corynebacterium species and other non-spore-forming gram-positive bacilli to 18 antimicrobial agents.

  F Soriano, J Zapardiel, E Nieto
• Clinical Trial | Comparative Study | Journal Article | Multicenter Study | Randomized Controlled Trial

  Randomized, double-blind comparison of single-dose regimens of rufloxacin and pefloxacin for acute uncomplicated cystitis in women. French Multicenter Urinary Tract Infection-Rufloxacin Group.

  A Jardin, M Cesana
• Comparative Study | Journal Article | Research Support, Non-U.S. Gov't

  Postantibiotic effects and postantibiotic sub-MIC effects of roxithromycin, clarithromycin, and azithromycin on respiratory tract pathogens.

  I Odenholt-Tornqvist, E Löwdin, O Cars
• Comparative Study | Journal Article

  Kinetic study of interaction between BRL 42715, beta-lactamases, and D-alanyl-D-alanine peptidases.

  A Matagne, P Ledent, D Monnaie, A Felici, M Jamin, X Raquet, M Galleni, D Klein, I François, J M Frère
• Comparative Study | Journal Article | Research Support, Non-U.S. Gov't

  Relationship between structure and convulsant properties of some beta-lactam antibiotics following intracerebroventricular microinjection in rats.

  A De Sarro, D Ammendola, M Zappala, S Grasso, G B De Sarro
• Comparative Study | Journal Article | Research Support, Non-U.S. Gov't

  In vitro activities of a streptogramin (RP59500), three macrolides, and an azalide against four respiratory tract pathogens.

  A L Barry, P C Fuchs
• Comparative Study | Journal Article | Research Support, Non-U.S. Gov't

  Survey of in vitro susceptibilities of Vibrio cholerae O1 and O139 to antimicrobial agents.

  T Yamamoto, G B Nair, M J Albert, C C Parodi, Y Takeda
• Clinical Trial | Comparative Study | Journal Article | Randomized Controlled Trial | Research Support, Non-U.S. Gov't

  High efficacy of short-term quinine-antibiotic combinations for treating adult malaria patients in an area in which malaria is hyperendemic.

  W Metzger, B Mordmüller, W Graninger, U Bienzle, P G Kremsner
• Journal Article | Research Support, Non-U.S. Gov't

  A novel glycylcycline, 9-(N,N-dimethylglycylamido)-6-demethyl-6-deoxytetracycline, is neither transported nor recognized by the transposon Tn10-encoded metal-tetracycline/H+ antiporter.

  Y Someya, A Yamaguchi, T Sawai
• Journal Article

  Explanations for high rates of eradication with triple therapy using metronidazole in patients harboring metronidazole-resistant Helicobacter pylori strains.

  A A van Zwet, J C Thijs, B de Graaf
• Journal Article

  Cerebrospinal fluid penetration of amikacin in children with community-acquired bacterial meningitis.

  J L Gaillard, C Silly, A Le Masne, B Mahut, F Lacaille, G Cheron, V Abadie, P Hubert, V Matha, C Coustere
• Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  High frequency of strains multiply resistant to ampicillin, trimethoprim-sulfamethoxazole, streptomycin, chloramphenicol, and tetracycline isolated from patients with shigellosis in northeastern Brazil during the period 1988 to 1993.

  A A Lima, N L Lima, M C Pinho, E A Barros Juñior, M J Teixeira, M C Martins, R L Guerrant
• Journal Article | Research Support, Non-U.S. Gov't

  Cloning, sequencing, and site-directed mutagenesis of beta-lactamase gene from Streptomyces fradiae Y59.

  S Kurai, H Urabe, H Ogawara
• Clinical Trial | Controlled Clinical Trial | Journal Article | Research Support, Non-U.S. Gov't

  Amikacin levels in bronchial secretions of 10 pneumonia patients with respiratory support treated once daily versus twice daily.

  C Santré, H Georges, J M Jacquier, O Leroy, C Beuscart, D Buguin, G Beaucaire
• Journal Article | Research Support, Non-U.S. Gov't

  Antimicrobial susceptibilities of Stomatococcus mucilaginosus and of Micrococcus spp.

  C von Eiff, M Herrmann, G Peters
• Journal Article

  In vivo correlates for Streptococcus pneumoniae penicillin resistance in acute otitis media.

  P Gehanno, G Lenoir, P Berche
• Clinical Trial | Journal Article | Randomized Controlled Trial

  Effect of food on absorption of cefpodoxime proxetil oral suspension in adults.

  M T Borin, K K Forbes