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Comparative Study | Journal Article | Research Support, U.S. Gov't, P.H.S.

The erythromycin resistance gene from the Bacteroides conjugal transposon Tcr Emr 7853 is nearly identical to ermG from Bacillus sphaericus.

A J Cooper, N B Shoemaker, A A Salyers
A J Cooper
Department of Microbiology, University of Illinois, Urbana 61801, USA. ajcooper@students.uiuc.edu
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N B Shoemaker
Department of Microbiology, University of Illinois, Urbana 61801, USA. ajcooper@students.uiuc.edu
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A A Salyers
Department of Microbiology, University of Illinois, Urbana 61801, USA. ajcooper@students.uiuc.edu
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DOI: 10.1128/AAC.40.2.506
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ABSTRACT

Tcr Emr 7853, from Bacteroides thetaiotaomicron 7853, is a large chromosomal conjugative transposon which encodes resistance to both tetracycline (Tcr) and erythromycin (Emr). The erythromycin resistance gene of Tcr Emr 7853 did not cross-hybridize with ermF, the Emr gene found on previously studied Bacteroides regular and conjugative transposons. We have cloned and sequenced the erythromycin resistance gene from Tcr Emr 7853. The DNA sequence of this gene was 99.6% identical to that of ermG from Bacillus sphaericus.

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The erythromycin resistance gene from the Bacteroides conjugal transposon Tcr Emr 7853 is nearly identical to ermG from Bacillus sphaericus.
A J Cooper, N B Shoemaker, A A Salyers
Antimicrobial Agents and Chemotherapy Feb 1996, 40 (2) 506-508; DOI: 10.1128/AAC.40.2.506

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The erythromycin resistance gene from the Bacteroides conjugal transposon Tcr Emr 7853 is nearly identical to ermG from Bacillus sphaericus.
A J Cooper, N B Shoemaker, A A Salyers
Antimicrobial Agents and Chemotherapy Feb 1996, 40 (2) 506-508; DOI: 10.1128/AAC.40.2.506
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