Table of Contents

Articles

• Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  Susceptibility of melanized and nonmelanized Cryptococcus neoformans to the melanin-binding compounds trifluoperazine and chloroquine.

  Y Wang, A Casadevall
• Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  Activities of bay Y 3118, levofloxacin, and ofloxacin alone or in combination with ethambutol against Mycobacterium avium complex in vitro, in human macrophages, and in beige mice.

  L E Bermudez, C B Inderlied, P Kolonoski, M Wu, L Barbara-Burnham, L S Young
• Journal Article | Research Support, Non-U.S. Gov't

  Preventive chemotherapy of tuberculosis in Cornell model mice with combinations of rifampin, isoniazid, and pyrazinamide.

  J Dhillon, J M Dickinson, K Sole, D A Mitchison
• Clinical Trial | Controlled Clinical Trial | Journal Article

  Single-dose and steady-state pharmacokinetics of a novel microfluidized suspension of atovaquone in human immunodeficiency virus-seropositive patients.

  R Dixon, A L Pozniak, H M Watt, P Rolan, J Posner
• Comparative Study | Journal Article

  Pharmacokinetics of trovafloxacin (CP-99,219), a new quinolone, in rats, dogs, and monkeys.

  R Teng, D Girard, T D Gootz, G Foulds, T E Liston
• Clinical Trial | Comparative Study | Journal Article

  Influence of maturation and growth on cefetamet pivoxil pharmacokinetics: rational dosing for infants.

  W L Hayton, J Kneer, R de Groot, K Stoeckel
• Journal Article | Meta-Analysis

  Factors influencing elimination and distribution of fleroxacin: metaanalysis of individual data from 10 pharmacokinetic studies.

  B G Reigner, H A Welker
• Journal Article | Research Support, Non-U.S. Gov't

  The macrolide-lincosamide-streptogramin B resistance phenotypes characterized by using a specifically deleted, antibiotic-sensitive strain of Streptomyces lividans.

  J L Pernodet, S Fish, M H Blondelet-Rouault, E Cundliffe
• Journal Article | Research Support, U.S. Gov't, P.H.S.

  Activity of oral atovaquone alone and in combination with antimony in experimental visceral leishmaniasis.

  H W Murray, J Hariprashad
• Journal Article

  Susceptibilities of Candida spp. to antifungal agents visualized by two-dimensional scatterplots of relative growth.

  F C Odds, G Dams, G Just, P Lewi
• Journal Article

  Stereospecific reduction of virginiamycin M1 as the virginiamycin resistance pathway in Streptomyces virginiae.

  C K Lee, M Minami, S Sakuda, T Nihira, Y Yamada
• Comparative Study | Journal Article | Research Support, Non-U.S. Gov't

  Differential in vitro activities of ionophore compounds against Plasmodium falciparum and mammalian cells.

  C Gumila, M L Ancelin, G Jeminet, A M Delort, G Miquel, H J Vial
• Clinical Trial | Journal Article | Randomized Controlled Trial

  Pharmacokinetics of conventional formulation versus fat emulsion formulation of amphotericin B in a group of patients with neutropenia.

  A Ayestarán, R M López, J B Montoro, A Estíbalez, L Pou, A Julià, A López, B Pascual
• Journal Article | Research Support, Non-U.S. Gov't

  Potential use of WR6026 as prophylaxis against transfusion-transmitted American trypanosomiasis.

  E Chiari, A B Oliveira, M A Prado, R J Alves, L M Galvão, F G Araujo
• Journal Article

  Characterization of beta-lactamase gene blaPER-2, which encodes an extended-spectrum class A beta-lactamase.

  A Bauernfeind, I Stemplinger, R Jungwirth, P Mangold, S Amann, E Akalin, O Anğ, C Bal, J M Casellas
• Journal Article

  In vitro antibacterial activity of omeprazole and its selectivity for Helicobacter spp. are dependent on incubation conditions.

  J E Sjöström, J Fryklund, T Kühler, H Larsson
• Journal Article | Research Support, Non-U.S. Gov't

  Twenty-four-hour area under the concentration-time curve/MIC ratio as a generic predictor of fluoroquinolone antimicrobial effect by using three strains of Pseudomonas aeruginosa and an in vitro pharmacodynamic model.

  K J Madaras-Kelly, B E Ostergaard, L B Hovde, J C Rotschafer
• Comparative Study | Journal Article

  Antituberculosis activities of clofazimine and its new analogs B4154 and B4157.

  V M Reddy, G Nadadhur, D Daneluzzi, J F O'Sullivan, P R Gangadharam
• Journal Article

  Amphotericin B enzyme-linked immunosorbent assay.

  J D Cleary, S W Chapman, J Deng, C J Lobb
• Journal Article | Research Support, U.S. Gov't, Non-P.H.S. | Research Support, U.S. Gov't, P.H.S.

  Pharmacokinetics of (-)-2'-3'-dideoxy-3'-thiacytidine in woodchucks.

  P Rajagopalan, F D Boudinot, C K Chu, B C Tennant, B H Baldwin, R F Schinazi
• Journal Article | Research Support, Non-U.S. Gov't

  Rifampin resistance in Neisseria meningitidis due to alterations in membrane permeability.

  F J Abadi, P E Carter, P Cash, T H Pennington
• Journal Article | Research Support, Non-U.S. Gov't

  Transport of the antibacterial agent oxazolidin-2-one and derivatives across intestinal (Caco-2) and renal (MDCK) epithelial cell lines.

  G Ranaldi, P Seneci, W Guba, K Islam, Y Sambuy
• Clinical Trial | Journal Article | Research Support, Non-U.S. Gov't

  Pharmacokinetics of [18F]fleroxacin in patients with acute exacerbations of chronic bronchitis and complicated urinary tract infection studied by positron emission tomography.

  A J Fischman, E Livni, J W Babich, N M Alpert, A Bonab, S Chodosh, F McGovern, P Kamitsuka, Y Y Liu, R Cleeland, B L Prosser, J A Correia, R H Rubin
• Journal Article | Research Support, Non-U.S. Gov't

  Eradication of mucoid Pseudomonas aeruginosa with fluid liposome-encapsulated tobramycin in an animal model of chronic pulmonary infection.

  C Beaulac, S Clément-Major, J Hawari, J Lagacé
• Journal Article | Research Support, Non-U.S. Gov't

  Effects of fasting on temporal variations in nephrotoxicity of gentamicin in rats.

  D Beauchamp, P Collin, L Grenier, M LeBrun, M Couture, L Thibault, G Labrecque, M G Bergeron
• Comparative Study | Journal Article

  Comparison of methodologies for synergism testing of drug combinations against resistant strains of Pseudomonas aeruginosa.

  D M Cappelletty, M J Rybak
• Journal Article

  Activity and mode of action of acridine compounds against Leishmania donovani.

  C M Mesa-Valle, J Castilla-Calvente, M Sanchez-Moreno, V Moraleda-Lindez, J Barbe, A Osuna
• Clinical Trial | Journal Article | Randomized Controlled Trial

  Continuous infusion versus intermittent administration of ceftazidime in critically ill patients with suspected gram-negative infections.

  A S Benko, D M Cappelletty, J A Kruse, M J Rybak
• Clinical Trial | Comparative Study | Journal Article | Randomized Controlled Trial

  Comparison of conventional dosing versus continuous-infusion vancomycin therapy for patients with suspected or documented gram-positive infections.

  J K James, S M Palmer, D P Levine, M J Rybak
• Comparative Study | Journal Article | Research Support, Non-U.S. Gov't

  Pharmacodynamics of once- or twice-daily levofloxacin versus vancomycin, with or without rifampin, against Staphylococcus aureus in an in vitro model with infected platelet-fibrin clots.

  S M Palmer, M J Rybak
• Journal Article | Research Support, U.S. Gov't, P.H.S.

  Effect of mitonafide analogs on topoisomerase II of Leishmania chagasi.

  K M Slunt, J M Grace, T L Macdonald, R D Pearson
• Journal Article | Research Support, Non-U.S. Gov't

  Quinolone-resistant mutants of escherichia coli DNA topoisomerase IV parC gene.

  Y Kumagai, J I Kato, K Hoshino, T Akasaka, K Sato, H Ikeda
• Journal Article | Research Support, Non-U.S. Gov't

  Characterization of the chromosomal cephalosporinases produced by Acinetobacter lwoffii and Acinetobacter baumannii clinical isolates.

  M Perilli, A Felici, A Oratore, G Cornaglia, G Bonfiglio, G M Rossolini, G Amicosante
• Comparative Study | Journal Article | Research Support, Non-U.S. Gov't

  In vitro antimicrobial activities and spectra of U-100592 and U-100766, two novel fluorinated oxazolidinones.

  R N Jones, D M Johnson, M E Erwin
• Journal Article | Research Support, U.S. Gov't, P.H.S.

  Identification of a class of sulfonamides highly active against dihydropteroate synthase form Toxoplasma gondii, Pneumocystis carinii, and Mycobacterium avium.

  L C Chio, L A Bolyard, M Nasr, S F Queener
• Journal Article | Research Support, Non-U.S. Gov't

  Predictors of effect of ampicillin-sulbactam against TEM-1 beta-lactamase-producing Escherichia coli in an in vitro dynamic model: enzyme activity versus MIC.

  A A Firsov, D Saverino, D Savarino, M Ruble, D Gilbert, B Manzano, A A Medeiros, S H Zinner
• In Vitro | Journal Article

  Uptake and intracellular activity of NM394, a new quinolone, in human polymorphonuclear leukocytes.

  M Ozaki, K Komori, M Matsuda, R Yamaguchi, T Honmura, Y Tomii, I Nishimura, T Nishino
• Comparative Study | Journal Article | Research Support, Non-U.S. Gov't

  In vitro activities of rifabutin, azithromycin, ciprofloxacin, clarithromycin, clofazimine, ethambutol, and amikacin in combinations of two, three, and four drugs against Mycobacterium avium.

  D M Yajko, C A Sanders, J J Madej, V L Cawthon, W K Hadley
• Journal Article | Research Support, Non-U.S. Gov't

  Antiviral efficacy in vivo of the anti-human immunodeficiency virus bicyclam SDZ SID 791 (JM 3100), an inhibitor of infectious cell entry.

  R Datema, L Rabin, M Hincenbergs, M B Moreno, S Warren, V Linquist, B Rosenwirth, J Seifert, J M McCune
• Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S.

  Use of standardized SCID-hu Thy/Liv mouse model for preclinical efficacy testing of anti-human immunodeficiency virus type 1 compounds.

  L Rabin, M Hincenbergs, M B Moreno, S Warren, V Linquist, R Datema, B Charpiot, J Seifert, H Kaneshima, J M McCune
• Clinical Trial | Journal Article

  Cerebrospinal fluid ceftazidime kinetics in patients with external ventriculostomies.

  R Nau, H W Prange, M Kinzig, A Frank, A Dressel, P Scholz, H Kolenda, F Sörgel
• Clinical Trial | Journal Article | Randomized Controlled Trial | Research Support, Non-U.S. Gov't

  Didanosine reduces atevirdine absorption in subjects with human immunodeficiency virus infections.

  G D Morse, M A Fischl, M J Shelton, M T Borin, M R Driver, M DeRemer, K Lee, C P Wajszczuk
• Journal Article | Research Support, Non-U.S. Gov't

  Susceptibilities of non-Pseudomonas aeruginosa gram-negative nonfermentative rods to ciprofloxacin, ofloxacin, levofloxacin, D-ofloxacin, sparfloxacin, ceftazidime, piperacillin, piperacillin-tazobactam, trimethoprim-sulfamethoxazole, and imipenem.

  S K Spangler, M A Visalli, M R Jacobs, P C Appelbaum
• Clinical Trial | Journal Article | Research Support, Non-U.S. Gov't

  Pharmacokinetics of sparfloxacin and serum bactericidal activity against pneumococci.

  M Trautmann, M Ruhnke, K Borner, J Wagner, P Koeppe
• Clinical Trial | Controlled Clinical Trial | Journal Article

  Penetration of cefetamet pivoxil and cefuroxime axetil into the maxillary sinus mucosa at steady state.

  K Stoeckel, M Harell, M Dan
• Journal Article

  Alteration of postantibiotic effect during one dosing interval of tobramycin, simulated in an in vitro pharmacokinetic model.

  J G den Hollander, J W Mouton, M P van Goor, F P Vleggaar, H A Verbrugh
• Clinical Trial | Journal Article | Randomized Controlled Trial | Research Support, Non-U.S. Gov't

  Penetration of ciprofloxacin and fleroxacin into biliary tract.

  C E Edmiston, E C Suarez, A P Walker, M P Demeure, C T Frantzides, W J Schulte, S D Wilson
• Clinical Trial | Comparative Study | Journal Article | Randomized Controlled Trial | Research Support, Non-U.S. Gov't

  Pharmacokinetics of oral fleroxacin in male and premenopausal female volunteers.

  J S Bertino, A N Nafziger
• Journal Article | Research Support, Non-U.S. Gov't

  Inhibition of duck hepatitis B virus replication by 2',3'-dideoxy-3'-fluoroguanosine in vitro and in vivo.

  P Hafkemeyer, A Keppler-Hafkemeyer, M A al Haya, M von Janta-Lipinski, E Matthes, C Lehmann, W B Offensperger, S Offensperger, W Gerok, H E Blum
• Journal Article

  Pharmacokinetics in nonhuman primates of a prototype carbapenem active against methicillin-resistant Staphylococcus aureus.

  J G Sundelof, R Thompson, K M White, M W Sasor, L Cama, H Kropp
• Comparative Study | Journal Article | Research Support, Non-U.S. Gov't

  In vitro activities of oxazolidinone compounds U100592 and U100766 against Staphylococcus aureus and Staphylococcus epidermidis.

  G W Kaatz, S M Seo
• Journal Article | Research Support, Non-U.S. Gov't

  Temporal variation in nephrotoxicity of low doses of isepamicin in rats.

  Y Yoshiyama, L Grenier, P Gourde, M Simard, L Lin, N J Morin, M G Bergeron, G Labrecque, D Beauchamp
• Comparative Study | Journal Article | Research Support, Non-U.S. Gov't

  In vitro susceptibilities of Bordetella pertussis and Bordetella parapertussis to four fluoroquinolones (levofloxacin, d-ofloxacin, ofloxacin, and ciprofloxacin), cefpirome, and meropenem.

  J E Hoppe, E Rahimi-Galougahi, G Seibert
• Comparative Study | Journal Article

  Efficacy of clarithromycin versus that of clindamycin for single-dose prophylaxis of experimental streptococcal endocarditis.

  D Vermot, J M Entenza, J Vouillamoz, M P Glauser, P Moreillon
• Clinical Trial | Journal Article | Randomized Controlled Trial

  Penetration of ceftriaxone (1 or 2 grams intravenously) into mediastinal and cardiac tissues in humans.

  C Martin, X Viviand, M Alaya, F Lokiec, K Ennabli, R Said, M Pecking
• Journal Article | Research Support, U.S. Gov't, P.H.S.

  Bleomycin therapy of experimental disseminated candidiasis in mice.

  J R Graybill, R Bocanegra, A Fothergill, M G Rinaldi
• Journal Article | Research Support, Non-U.S. Gov't

  Influence of experimental rat model of multiple organ dysfunction on cefepime and amikacin pharmacokinetics.

  O Mimoz, A Jacolot, C Padoin, J Quillard, M Tod, K Louchahi, K Samii, O Petitjean
• Comparative Study | Journal Article

  In vitro susceptibilities of clinical and environmental isolates of Cryptococcus neoformans to five antifungal drugs.

  S P Franzot, J S Hamdan
• Clinical Trial | Journal Article | Research Support, Non-U.S. Gov't

  Distribution of azithromycin into brain tissue, cerebrospinal fluid, and aqueous humor of the eye.

  S Jaruratanasirikul, R Hortiwakul, T Tantisarasart, N Phuenpathom, S Tussanasunthornwong