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Journal Article | Research Support, Non-U.S. Gov't

Canadian national survey of prevalence of antimicrobial resistance among clinical isolates of Streptococcus pneumoniae. Canadian Bacterial Surveillance Network.

A E Simor, M Louie, D E Low
A E Simor
Department of Microbiology, Sunnybrook Health Science Centre, Toronto, Ontario, Canada.
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M Louie
Department of Microbiology, Sunnybrook Health Science Centre, Toronto, Ontario, Canada.
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D E Low
Department of Microbiology, Sunnybrook Health Science Centre, Toronto, Ontario, Canada.
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DOI: 10.1128/AAC.40.9.2190
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ABSTRACT

The antimicrobial susceptibilities of 1,089 clinical isolates of Streptococcus pneumoniae obtained from 39 laboratories across Canada between October 1994 and August 1995 were determined. A total of 91 isolates (8.4%) demonstrated intermediate resistance (MIC, 0.1 to 1.0 microgram/ml) and 36 (3.3%) had high-level resistance (MIC, > or = 2.0 micrograms/ml) to penicillin. Penicillin-resistant strains were more likely to have been recovered from normally sterile sites (P = 0.005) and to be cross-resistant to several beta-lactam and non-beta-lactam antimicrobial agents (P < 0.05). These results indicate that there has been a recent significant increase in the prevalence of antibiotic-resistant S. pneumoniae in Canada.

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Canadian national survey of prevalence of antimicrobial resistance among clinical isolates of Streptococcus pneumoniae. Canadian Bacterial Surveillance Network.
A E Simor, M Louie, D E Low
Antimicrobial Agents and Chemotherapy Sep 1996, 40 (9) 2190-2193; DOI: 10.1128/AAC.40.9.2190

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Canadian national survey of prevalence of antimicrobial resistance among clinical isolates of Streptococcus pneumoniae. Canadian Bacterial Surveillance Network.
A E Simor, M Louie, D E Low
Antimicrobial Agents and Chemotherapy Sep 1996, 40 (9) 2190-2193; DOI: 10.1128/AAC.40.9.2190
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