DOI: 10.1128/AAC.42.1.161
Article Figures & Data
Tables
- Table 1.
In vitro susceptibilities of 394 clinical yeast isolates to voriconazole and other antifungal agents
Organism (no. of isolates) Antifungal agent MIC (μg/ml) Range 50% 90% C. albicans(206) Voriconazole ≤0.015–>16 0.03 0.06 Itraconazole 0.03–>8 0.125 0.25 Fluconazole ≤0.125–>128 0.25 2 Amphotericin B 0.5–2 1 1 5FC ≤0.06–>128 0.25 4 C. glabrata(77) Voriconazole 0.03–8 0.5 1 Itraconazole 0.06–>8 1 4 Fluconazole 0.25–>128 16 64 Amphotericin B 1–2 1 2 5FC ≤0.06–16 0.125 0.25 C. tropicalis(54) Voriconazole ≤0.015–>16 0.06 0.125 Itraconazole 0.03–>8 0.25 0.5 Fluconazole 0.25–>128 0.5 2 Amphotericin B 0.5–2 1 2 5FC ≤0.06–>128 0.25 1 C. parapsilosis(40) Voriconazole ≤0.015–1 0.06 0.25 Itraconazole 0.125–2 0.25 0.5 Fluconazole 0.25–16 1 8 Amphotericin B 0.5–2 1 2 5FC ≤0.06–>128 0.125 1 C. krusei(17) Voriconazole 0.25–1 0.5 1 Itraconazole 0.5–2 1 2 Fluconazole 32–128 64 128 Amphotericin B 1–2 2 2 5FC 16–64 32 64 All organisms (394) Voriconazole ≤0.015–>16 0.06 0.5 Itraconazole 0.03–>8 0.25 2 Fluconazole ≤0.125–>128 0.5 16 Amphotericin B 0.5–2 1 2 5FC ≤0.06–>128 0.25 8
