Article Figures & Data
Figures
- Fig. 1.
Mean (plus SEM) neutrophil and phagocytosing neutrophil counts in BAL fluid (A) and MPO levels in lung homogenates (B) of mice 4 h after the last injection of S. pneumoniae (BACT), CEF, S. pneumoniae plus CEF (BACT-CEF), or the appropriate diluent (CONTROL). ∗∗∗, P < 0.001 compared with counts in control mice.
- Fig. 2.
Mean (plus SEM) levels of TNF-α (A) and IL-6 (B) in BAL fluid and of TNF-α (C), IL-6 (D), and IL-1α (E) in lung homogenates 4 h after the last injection of S. pneumoniae (BACT), CEF, S. pneumoniae plus CEF (BACT-CEF), or the appropriate diluent (CONTROL). ∗, ∗∗, and ∗∗∗, P < 0.05, P < 0.01, andP < 0.001 compared with control value, respectively.
- Fig. 3.
Electron microscopy of lung architecture of mice infected with heat-killed S. pneumoniae and treated with CEF (A) or control diluent (B). Tissue is well preserved and few neutrophils are seen after therapy, while in the untreated infected mouse the tissue contains cell debris and numerous neutrophils. T2, type 2 pneumocytes; A, alveolus; I, interstitium; N, neutrophils; D, debris. Magnification, ×8,300.
