DOI: 10.1128/AAC.43.12.3042
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Tables
- Table 1.
Antibiotic resistance in MRSA and derived benzalkonium chloride-resistant mutants
Antibiotic MIC (μg/ml)a MRSAb MSSAc Parent BZ-R-1 BZ-R-2 BZ-R-3 BZ-R-4 BZ-R-5 Oxacillin 16 512 512 128 64 64 0.3 Cloxacillin 0.5 256 512 128 0.5 8 0.3 Moxalactam 64 256 1024 512 256 256 8 Flomoxef 8 128 128 64 16 16 0.5 Cefmetazole 8 128 64 64 32 32 1 Cefazolin 64 128 128 64 128 128 0.5 Cephalothin 64 128 128 128 128 128 0.5 Ampicillin 16 32 32 16 32 16 0.5 Chloramphenicol 4 4 4 4 4 4 4 Ofloxacin 8 32 32 16 16 16 0.3 Tetracycline 128 128 128 32 128 128 NDd Kanamycin 256 512 512 512 256 256 ND Benzalkonium chloride 5 10 10 10 10 10 0.7 ↵a Full growth of bacteria in LB liquid medium was appropriately diluted, and the bacterial suspension (2 × 103) was streaked on LB agar plates containing various concentrations of antibiotics, followed by incubation at 37°C for 72 h.
↵b MRSA strains were examined by identifying themecA gene by PCR (3) in strains of S. aureus isolated in Kyushu Univeristy Hospital.
↵c MSSA, methicillin-susceptible S. aureus.
↵d ND, not determined.
