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Experimental Therapeutics

Ultrasonic Enhancement of Antibiotic Action on Escherichia coli Biofilms: an In Vivo Model

Andrea M. Rediske, Beverly L. Roeder, Maren K. Brown, Jared L. Nelson, Rachel L. Robison, David O. Draper, G. Bruce Schaalje, Richard A. Robison, William G. Pitt
Andrea M. Rediske
Department of Microbiology,
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Beverly L. Roeder
Department of Animal Science,
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Maren K. Brown
Department of Microbiology,
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Jared L. Nelson
Department of Chemical Engineering,
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Rachel L. Robison
Department of Microbiology,
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David O. Draper
Department of Physical Education, and
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G. Bruce Schaalje
Department of Statistics, Brigham Young University, Provo, Utah
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Richard A. Robison
Department of Microbiology,
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William G. Pitt
Department of Chemical Engineering,
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DOI: 10.1128/AAC.43.5.1211
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    Fig. 1.

    Results for biofilms implanted in rabbits treated with antibiotics and 100- or 300-mW/cm2 ultrasound. The data are log10 viable CFU from biofilm-coated disks. Not Implanted, control disks grown under the same conditions and at the same time as those implanted into the rabbit but plated immediately to determine average CFU in the original biofilm; Implanted Biofilm, disks recovered from the rabbit which received no treatment, removed 48 h postplacement. Error bars indicate one standard deviation from the mean.

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Ultrasonic Enhancement of Antibiotic Action on Escherichia coli Biofilms: an In Vivo Model
Andrea M. Rediske, Beverly L. Roeder, Maren K. Brown, Jared L. Nelson, Rachel L. Robison, David O. Draper, G. Bruce Schaalje, Richard A. Robison, William G. Pitt
Antimicrobial Agents and Chemotherapy May 1999, 43 (5) 1211-1214; DOI: 10.1128/AAC.43.5.1211

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Ultrasonic Enhancement of Antibiotic Action on Escherichia coli Biofilms: an In Vivo Model
Andrea M. Rediske, Beverly L. Roeder, Maren K. Brown, Jared L. Nelson, Rachel L. Robison, David O. Draper, G. Bruce Schaalje, Richard A. Robison, William G. Pitt
Antimicrobial Agents and Chemotherapy May 1999, 43 (5) 1211-1214; DOI: 10.1128/AAC.43.5.1211
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KEYWORDS

biofilms
Escherichia coli
Gentamicins
Prosthesis-Related Infections

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