Ultrasonic Enhancement of Antibiotic Action on Escherichia coli Biofilms: an In Vivo Model

Results for biofilms implanted in rabbits treated with antibiotics and 100- or 300-mW/cm² ultrasound. The data are log₁₀ viable CFU from biofilm-coated disks. Not Implanted, control disks grown under the same conditions and at the same time as those implanted into the rabbit but plated immediately to determine average CFU in the original biofilm; Implanted Biofilm, disks recovered from the rabbit which received no treatment, removed 48 h postplacement. Error bars indicate one standard deviation from the mean.