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Pharmacology

Pharmacokinetics of SCH 56592, a New Azole Broad-Spectrum Antifungal Agent, in Mice, Rats, Rabbits, Dogs, and Cynomolgus Monkeys

Amin A. Nomeir, Pramila Kumari, Mary Jane Hilbert, Samir Gupta, David Loebenberg, Anthony Cacciapuoti, Roberta Hare, George H. Miller, Chin-Chung Lin, Mitchell N. Cayen
Amin A. Nomeir
Departments of Drug Metabolism and Pharmacokinetics,
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Pramila Kumari
Departments of Drug Metabolism and Pharmacokinetics,
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Mary Jane Hilbert
Biotechnology, and
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Samir Gupta
Departments of Drug Metabolism and Pharmacokinetics,
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David Loebenberg
Chemotherapy and Molecular Genetics, Schering-Plough Research Institute, Kenilworth, New Jersey
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Anthony Cacciapuoti
Chemotherapy and Molecular Genetics, Schering-Plough Research Institute, Kenilworth, New Jersey
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Roberta Hare
Chemotherapy and Molecular Genetics, Schering-Plough Research Institute, Kenilworth, New Jersey
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George H. Miller
Chemotherapy and Molecular Genetics, Schering-Plough Research Institute, Kenilworth, New Jersey
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Chin-Chung Lin
Departments of Drug Metabolism and Pharmacokinetics,
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Mitchell N. Cayen
Departments of Drug Metabolism and Pharmacokinetics,
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DOI: 10.1128/AAC.44.3.727-731.2000
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Article Information

DOI 
https://doi.org/10.1128/AAC.44.3.727-731.2000
PubMed 
10681346

Published By 
American Society for Microbiology Journals
History 
  • Received February 16, 1999
  • Returned for modification September 20, 1999
  • Accepted November 24, 1999
  • Published online March 1, 2000.

Copyright & Usage 
Copyright © 2000 American Society for Microbiology

Author Information

  1. Amin A. Nomeir1*,
  2. Pramila Kumari1,
  3. Mary Jane Hilbert2,
  4. Samir Gupta1,
  5. David Loebenberg3,
  6. Anthony Cacciapuoti3,
  7. Roberta Hare3,
  8. George H. Miller3,
  9. Chin-Chung Lin1 and
  10. Mitchell N. Cayen1
  1. Departments of Drug Metabolism and Pharmacokinetics,1
  2. Biotechnology,2 and
  3. Chemotherapy and Molecular Genetics,3 Schering-Plough Research Institute, Kenilworth, New Jersey
  • ↵* Corresponding author. Mailing address: Department of Drug Metabolism and Pharmacokinetics, Schering-Plough Research Institute, Mail Stop 2880, Kenilworth, NJ 07033-1310. Phone: (908) 740-3190. Fax: (908) 740-3966. E-mail:Amin.Nomeir{at}sprcorp.com.

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Pharmacokinetics of SCH 56592, a New Azole Broad-Spectrum Antifungal Agent, in Mice, Rats, Rabbits, Dogs, and Cynomolgus Monkeys
Amin A. Nomeir, Pramila Kumari, Mary Jane Hilbert, Samir Gupta, David Loebenberg, Anthony Cacciapuoti, Roberta Hare, George H. Miller, Chin-Chung Lin, Mitchell N. Cayen
Antimicrobial Agents and Chemotherapy Mar 2000, 44 (3) 727-731; DOI: 10.1128/AAC.44.3.727-731.2000

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Pharmacokinetics of SCH 56592, a New Azole Broad-Spectrum Antifungal Agent, in Mice, Rats, Rabbits, Dogs, and Cynomolgus Monkeys
Amin A. Nomeir, Pramila Kumari, Mary Jane Hilbert, Samir Gupta, David Loebenberg, Anthony Cacciapuoti, Roberta Hare, George H. Miller, Chin-Chung Lin, Mitchell N. Cayen
Antimicrobial Agents and Chemotherapy Mar 2000, 44 (3) 727-731; DOI: 10.1128/AAC.44.3.727-731.2000
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KEYWORDS

antifungal agents
triazoles

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