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Mechanisms of Action: Physiological Effects

Inhibitors of Sterol Biosynthesis and Amphotericin B Reduce the Viability of Pneumocystis carinii f. sp.carinii

Edna S. Kaneshiro, Margaret S. Collins, Melanie T. Cushion
Edna S. Kaneshiro
Department of Biological Sciences, University of Cincinnati, Cincinnati, Ohio 45221;
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Margaret S. Collins
Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267; and
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Melanie T. Cushion
Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267; and
Veterans Administration Medical Center, Cincinnati, Ohio
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DOI: 10.1128/AAC.44.6.1630-1638.2000
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Article Information

DOI 
https://doi.org/10.1128/AAC.44.6.1630-1638.2000
PubMed 
10817720

Published By 
American Society for Microbiology Journals
History 
  • Received December 17, 1999
  • Returned for modification February 7, 2000
  • Accepted March 21, 2000
  • Published online June 1, 2000.

Copyright & Usage 
Copyright © 2000 American Society for Microbiology

Author Information

  1. Edna S. Kaneshiro1*,
  2. Margaret S. Collins2 and
  3. Melanie T. Cushion2,3
  1. Department of Biological Sciences, University of Cincinnati, Cincinnati, Ohio 452211;
  2. Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio 452672; and
  3. Veterans Administration Medical Center, Cincinnati, Ohio3
  • ↵* Corresponding author. Mailing address: Department of Biological Sciences, University of Cincinnati, Cincinnati, OH 45221-0006. Phone: (513) 556-9712. Fax: (513) 556-5280. E-mail:Edna.Kaneshiro{at}uc.edu.

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Inhibitors of Sterol Biosynthesis and Amphotericin B Reduce the Viability of Pneumocystis carinii f. sp.carinii
Edna S. Kaneshiro, Margaret S. Collins, Melanie T. Cushion
Antimicrobial Agents and Chemotherapy Jun 2000, 44 (6) 1630-1638; DOI: 10.1128/AAC.44.6.1630-1638.2000

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Inhibitors of Sterol Biosynthesis and Amphotericin B Reduce the Viability of Pneumocystis carinii f. sp.carinii
Edna S. Kaneshiro, Margaret S. Collins, Melanie T. Cushion
Antimicrobial Agents and Chemotherapy Jun 2000, 44 (6) 1630-1638; DOI: 10.1128/AAC.44.6.1630-1638.2000
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KEYWORDS

amphotericin B
Enzyme Inhibitors
Lanosterol
Pneumocystis
Sterols

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