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Experimental Therapeutics

Efficacy of the Echinocandin Caspofungin against Disseminated Aspergillosis and Candidiasis in Cyclophosphamide-Induced Immunosuppressed Mice

George K. Abruzzo, Charles J. Gill, Amy M. Flattery, Li Kong, Claire Leighton, Jeffrey G. Smith, V. Bill Pikounis, Ken Bartizal, Hugh Rosen
George K. Abruzzo
Infectious Diseases,
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Charles J. Gill
Infectious Diseases,
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Amy M. Flattery
Infectious Diseases,
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Li Kong
Infectious Diseases,
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Claire Leighton
Infectious Diseases,
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Jeffrey G. Smith
Virus and Cell Biology,
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V. Bill Pikounis
Biometrics Research, and
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Ken Bartizal
Animal Health, Merck Research Laboratories, Rahway, New Jersey 07065-0900
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Hugh Rosen
Infectious Diseases,
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DOI: 10.1128/AAC.44.9.2310-2318.2000
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Article Information

DOI 
https://doi.org/10.1128/AAC.44.9.2310-2318.2000
PubMed 
10952573

Published By 
American Society for Microbiology Journals
History 
  • Received November 12, 1999
  • Returned for modification March 30, 2000
  • Accepted June 12, 2000
  • Published online September 1, 2000.

Copyright & Usage 
Copyright © 2000 American Society for Microbiology

Author Information

  1. George K. Abruzzo1*,
  2. Charles J. Gill1,
  3. Amy M. Flattery1,
  4. Li Kong1,
  5. Claire Leighton1,
  6. Jeffrey G. Smith2,
  7. V. Bill Pikounis3,
  8. Ken Bartizal4 and
  9. Hugh Rosen1
  1. Infectious Diseases,1
  2. Virus and Cell Biology,2
  3. Biometrics Research,3 and
  4. Animal Health,4 Merck Research Laboratories, Rahway, New Jersey 07065-0900
  • ↵* Corresponding author. Mailing address: Infectious Diseases (RY80T-100), Merck Research Laboratories, P.O. Box 2000, Rahway, NJ 07065-0900. Phone: (732) 594-6263. Fax: (732) 594-5700. E-mail: george_abruzzo{at}merck.com.

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Efficacy of the Echinocandin Caspofungin against Disseminated Aspergillosis and Candidiasis in Cyclophosphamide-Induced Immunosuppressed Mice
George K. Abruzzo, Charles J. Gill, Amy M. Flattery, Li Kong, Claire Leighton, Jeffrey G. Smith, V. Bill Pikounis, Ken Bartizal, Hugh Rosen
Antimicrobial Agents and Chemotherapy Sep 2000, 44 (9) 2310-2318; DOI: 10.1128/AAC.44.9.2310-2318.2000

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Efficacy of the Echinocandin Caspofungin against Disseminated Aspergillosis and Candidiasis in Cyclophosphamide-Induced Immunosuppressed Mice
George K. Abruzzo, Charles J. Gill, Amy M. Flattery, Li Kong, Claire Leighton, Jeffrey G. Smith, V. Bill Pikounis, Ken Bartizal, Hugh Rosen
Antimicrobial Agents and Chemotherapy Sep 2000, 44 (9) 2310-2318; DOI: 10.1128/AAC.44.9.2310-2318.2000
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KEYWORDS

Anti-Bacterial Agents
antifungal agents
aspergillosis
candidiasis
cyclophosphamide
peptides
Peptides, Cyclic

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