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Mechanisms of Resistance

Characterization of Class 1 Integrons from Pseudomonas aeruginosa That Contain the blaVIM-2Carbapenem-Hydrolyzing β-Lactamase Gene and of Two Novel Aminoglycoside Resistance Gene Cassettes

Laurent Poirel, Thierry Lambert, Salih Türkoglü, Esthel Ronco, Jean-Louis Gaillard, Patrice Nordmann
Laurent Poirel
Service de Bactériologie-Virologie, Hôpital de Bicêtre, Assistance Publique/Hôpitaux de Paris, Faculté de Médecine Paris-Sud, 94275 Le Kremlin-Bicêtre,
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Thierry Lambert
Centre d'Etudes Pharmaceutiques, 92296 Châtenay-Malabry,and
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Salih Türkoglü
Service de Bactériologie-Virologie, Hôpital de Bicêtre, Assistance Publique/Hôpitaux de Paris, Faculté de Médecine Paris-Sud, 94275 Le Kremlin-Bicêtre,
Department of Virology and Immunology, Istanbul Faculty of Medicine, 34390 Capa Istanbul, Turkey
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Esthel Ronco
Service de Microbiologie, Hôpital Raymond Poincaré, Assistance Publique Hôpitaux de Paris, Faculté de Médecine Paris-Ouest, 92380 Garches, France, and
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Jean-Louis Gaillard
Service de Microbiologie, Hôpital Raymond Poincaré, Assistance Publique Hôpitaux de Paris, Faculté de Médecine Paris-Ouest, 92380 Garches, France, and
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Patrice Nordmann
Service de Bactériologie-Virologie, Hôpital de Bicêtre, Assistance Publique/Hôpitaux de Paris, Faculté de Médecine Paris-Sud, 94275 Le Kremlin-Bicêtre,
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DOI: 10.1128/AAC.45.2.546-552.2001
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Article Information

DOI 
https://doi.org/10.1128/AAC.45.2.546-552.2001
PubMed 
11158753

Published By 
American Society for Microbiology Journals
History 
  • Received May 19, 2000
  • Returned for modification August 24, 2000
  • Accepted November 17, 2000
  • Published online February 1, 2001.

Copyright & Usage 
Copyright © 2001 American Society for Microbiology

Author Information

  1. Laurent Poirel1,
  2. Thierry Lambert2,
  3. Salih Türkoglü1,3,
  4. Esthel Ronco4,
  5. Jean-Louis Gaillard4 and
  6. Patrice Nordmann1*
  1. Service de Bactériologie-Virologie, Hôpital de Bicêtre, Assistance Publique/Hôpitaux de Paris, Faculté de Médecine Paris-Sud, 94275 Le Kremlin-Bicêtre,1
  2. Centre d'Etudes Pharmaceutiques, 92296 Châtenay-Malabry,2and
  3. Service de Microbiologie, Hôpital Raymond Poincaré, Assistance Publique Hôpitaux de Paris, Faculté de Médecine Paris-Ouest, 92380 Garches,4 France, and
  4. Department of Virology and Immunology, Istanbul Faculty of Medicine, 34390 Capa Istanbul, Turkey3
  • ↵* Corresponding author. Mailing address: Service de Bactériologie-Virologie, Hôpital de Bicêtre, 78 rue du Général Leclerc, 94275 Le Kremlin-Bicêtre cedex, France. Phone: 33 1 45 21 36 32. Fax: 33 1 45 21 63 40. E-mail:nordmann.patrice{at}bct.ap-hop-paris.fr.

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Characterization of Class 1 Integrons from Pseudomonas aeruginosa That Contain the blaVIM-2Carbapenem-Hydrolyzing β-Lactamase Gene and of Two Novel Aminoglycoside Resistance Gene Cassettes
Laurent Poirel, Thierry Lambert, Salih Türkoglü, Esthel Ronco, Jean-Louis Gaillard, Patrice Nordmann
Antimicrobial Agents and Chemotherapy Feb 2001, 45 (2) 546-552; DOI: 10.1128/AAC.45.2.546-552.2001

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Characterization of Class 1 Integrons from Pseudomonas aeruginosa That Contain the blaVIM-2Carbapenem-Hydrolyzing β-Lactamase Gene and of Two Novel Aminoglycoside Resistance Gene Cassettes
Laurent Poirel, Thierry Lambert, Salih Türkoglü, Esthel Ronco, Jean-Louis Gaillard, Patrice Nordmann
Antimicrobial Agents and Chemotherapy Feb 2001, 45 (2) 546-552; DOI: 10.1128/AAC.45.2.546-552.2001
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KEYWORDS

Anti-Bacterial Agents
carbapenems
Genes, Bacterial
Pseudomonas aeruginosa
beta-lactamases

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