Antimicrobial Agents and Chemotherapy: 45 (6)

June 1, 2001; Volume 45,Issue 6

Mechanisms of Resistance

Mechanisms of Resistance
Effect of Drug Concentration on Emergence of Macrolide Resistance in Mycobacterium avium
Kevin A. Nash
Mechanisms of Resistance
Oxacillinase-Mediated Resistance to Cefepime and Susceptibility to Ceftazidime in Pseudomonas aeruginosa
Daniel Aubert, Laurent Poirel, Jacqueline Chevalier, Sophie Leotard, Jean-Marie Pages, Patrice Nordmann
Mechanisms of Resistance
Molecular Basis of Rifampin and Isoniazid Resistance in Mycobacterium bovis Strains Isolated in Sardinia, Italy
L. A. Sechi, S. Zanetti, M. Sanguinetti, P. Molicotti, L. Romano, G. Leori, G. Delogu, S. Boccia, M. La Sorda, G. Fadda
Mechanisms of Resistance
Association of Amino Acid Substitutions in Penicillin-Binding Protein 3 with β-Lactam Resistance in β-Lactamase-Negative Ampicillin-Resistant Haemophilus influenzae
Kimiko Ubukata, Yumi Shibasaki, Kentarou Yamamoto, Naoko Chiba, Keiko Hasegawa, Yasuo Takeuchi, Keisuke Sunakawa, Matsuhisa Inoue, Masatoshi Konno
Mechanisms of Resistance
Teicoplanin Stress-Selected Mutations Increasing ς^B Activity in Staphylococcus aureus
Markus Bischoff, Brigitte Berger-Bächi
Mechanisms of Resistance
Real-Time PCR and Melting Curve Analysis for Reliable and Rapid Detection of SHV Extended-Spectrum β-Lactamases
Corinne C. Randegger, Herbert Hächler
Mechanisms of Resistance
Multidrug Efflux Pumps: Expression Patterns and Contribution to Antibiotic Resistance in Pseudomonas aeruginosa Biofilms
Teresa R. De Kievit, Michael D. Parkins, Richard J. Gillis, Ramakrishnan Srikumar, Howard Ceri, Keith Poole, Barbara H. Iglewski, Douglas G. Storey
Mechanisms of Resistance
C-Terminal Region of Pseudomonas aeruginosa Outer Membrane Porin OprD Modulates Susceptibility to Meropenem
Simone F. Epp, Thilo Köhler, Patrick Plésiat, Mehri Michéa-Hamzehpour, Joachim Frey, Jean-Claude Pechère
Mechanisms of Resistance
Resistance Studies with Daptomycin
Jared A. Silverman, Nicole Oliver, Ted Andrew, Tongchuan Li
Mechanisms of Resistance
Activation of Multiple Antibiotic Resistance in Uropathogenic Escherichia coli Strains by Aryloxoalcanoic Acid Compounds
Claudia Balagué, Eleonora Garcı́a Véscovi
Mechanisms of Resistance
CENTA as a Chromogenic Substrate for Studying β-Lactamases
Carine Bebrone, Catherine Moali, Florence Mahy, Sandrine Rival, Jean Denis Docquier, Gian Maria Rossolini, Jacques Fastrez, Rex F. Pratt, Jean-Marie Frère, Moreno Galleni
Mechanisms of Resistance
Expression of Multidrug Efflux Pump SmeDEF by Clinical Isolates of Stenotrophomonas maltophilia
Ana Alonso, Jose L. Martinez
Mechanisms of Resistance
Mechanisms of Macrolide Resistance in Clinical Group B Streptococci Isolated in France
Frederic Fitoussi, Chawki Loukil, Isabelle Gros, Olivier Clermont, Patricia Mariani, Stephane Bonacorsi, Isabelle Le Thomas, Dominique Deforche, Edouard Bingen

Antiviral Agents

Antiviral Agents
Alkylglycerol Prodrugs of Phosphonoformate Are Potent In Vitro Inhibitors of Nucleoside-Resistant Human Immunodeficiency Virus Type 1 and Select for Resistance Mutations That Suppress Zidovudine Resistance
Jennifer L. Hammond, Dianna L. Koontz, Holly Z. Bazmi, James R. Beadle, Saskia E. Hostetler, Ganesh D. Kini, Kathy A. Aldern, Douglas D. Richman, Karl Y. Hostetler, John W. Mellors
Antiviral Agents
Selection and Characterization of Varicella-Zoster Virus Variants Resistant to (R)-9-[4-Hydroxy-2-(Hydroxymethy)Butyl]Guanine
Teresa I. Ng, Yan Shi, H. Janette Huffaker, Warren Kati, Yaya Liu, Chih-Ming Chen, Zhen Lin, Clarence Maring, William E. Kohlbrenner, Akhteruzzaman Molla
Antiviral Agents
Thermoreversible Gel Formulations Containing Sodium Lauryl Sulfate or n-Lauroylsarcosine as Potential Topical Microbicides against Sexually Transmitted Diseases
Sylvie Roy, Pierrette Gourde, Jocelyne Piret, André Désormeaux, Julie Lamontagne, Caroline Haineault, Rabeea F. Omar, Michel G. Bergeron
Antiviral Agents
Cross-Resistance Testing of Antihepadnaviral Compounds Using Novel Recombinant Baculoviruses Which Encode Drug-Resistant Strains of Hepatitis B Virus
William E. Delaney, Ros Edwards, Danni Colledge, Tim Shaw, Joseph Torresi, Thomas G. Miller, Harriet C. Isom, C. Thomas Bock, Michael P. Manns, Christian Trautwein, Stephen Locarnini
Antiviral Agents
Genotypic and Phenotypic Resistance Patterns of Human Immunodeficiency Virus Type 1 Variants with Insertions or Deletions in the Reverse Transcriptase (RT): Multicenter Study of Patients Treated with RT Inhibitors
Bernard Masquelier, Esther Race, Catherine Tamalet, Diane Descamps, Jacques Izopet, Claudine Buffet-Janvresse, Annick Ruffault, Ali Si Mohammed, Jacqueline Cottalorda, Anne Schmuck, Vincent Calvez, Elisabeth Dam, Hervé Fleury, Françoise Brun-Vézinet, the ANRS AC11 Resistance Study Group

Experimental Therapeutics

Experimental Therapeutics
Treatment of Tuberculosis Using a Combination of Sustained-Release Rifampin-Loaded Microspheres and Oral Dosing with Isoniazid
Debra C. Quenelle, Gary A. Winchester, Jay K. Staas, Esther L. W. Barrow, William W. Barrow
Experimental Therapeutics
Activities of Newer Fluoroquinolones against Ciprofloxacin-Resistant Streptococcus pneumoniae
Elizabeth A. Coyle, Glenn W. Kaatz, Michael J. Rybak
Experimental Therapeutics
In Vivo Efficacy of the New Ketolide Telithromycin (HMR 3647) in Murine Infection Models
Alain Bonnefoy, Michele Guitton, Carole Delachaume, Pascal Le Priol, Anne-Marie Girard
Experimental Therapeutics
Trifluoromethionine, a Prodrug Designed against Methionine γ-Lyase-Containing Pathogens, Has Efficacy In Vitro and In Vivo against Trichomonas vaginalis
Graham H. Coombs, Jeremy C. Mottram
Experimental Therapeutics
Atovaquone Nanosuspensions Show Excellent Therapeutic Effect in a New Murine Model of Reactivated Toxoplasmosis
Nadja Schöler, Karsten Krause, Oliver Kayser, Rainer H. Müller, Klaus Borner, Helmut Hahn, Oliver Liesenfeld
Experimental Therapeutics
Inhibition of Group A Streptococcus Infection by Carboxyfullerene
Nina Tsao, Tien-Yau Luh, Chen-Kung Chou, Jiunn-Jong Wu, Yee-Shin Lin, Huan-Yao Lei
Experimental Therapeutics
Human Malaria in Immunocompromised Mice: New In Vivo Model for Chemotherapy Studies
A. Moreno, E. Badell, N. Van Rooijen, P. Druilhe
Experimental Therapeutics
Correlation between Antifungal Susceptibilities ofCoccidioides immitis In Vitro and Antifungal Treatment with Caspofungin in a Mouse Model
Gloria M. González, Rolando Tijerina, Laura K. Najvar, Rosie Bocanegra, Michael Luther, Michael G. Rinaldi, John R. Graybill
Experimental Therapeutics
Activities of Hexadecylphosphocholine (Miltefosine), AmBisome, and Sodium Stibogluconate (Pentostam) againstLeishmania donovani in Immunodeficient scidMice
Patricia Escobar, Vanessa Yardley, Simon L. Croft

Mechanisms of Action

Mechanisms of Action: Physiological Effects
Contributions of the 8-Methoxy Group of Gatifloxacin to Resistance Selectivity, Target Preference, and Antibacterial Activity against Streptococcus pneumoniae
Hideyuki Fukuda, Ryuta Kishii, Masaya Takei, Masaki Hosaka
Mechanisms of Action: Physiological Effects
Genomic Profiling of the Response of Candida albicans to Itraconazole Treatment Using a DNA Microarray
Marianne D. De Backer, Tatiana Ilyina, Xiao-Jun Ma, Sandy Vandoninck, Walter H. M. L. Luyten, Hugo Vanden Bossche
Mechanisms of Action: Physiological Effects
Proinflammatory Activity of a Cecropin-Like Antibacterial Peptide from Helicobacter pylori
Johan Bylund, Thierry Christophe, Francois Boulay, Thomas Nyström, Anna Karlsson, Claes Dahlgren
Mechanisms of Action: Physiological Effects
Mechanism of Synergy between Epigallocatechin Gallate and β-Lactams against Methicillin-Resistant Staphylococcus aureus
Wei-Hua Zhao, Zhi-Qing Hu, Sachie Okubo, Yukihiko Hara, Tadakatsu Shimamura
Mechanisms of Action: Physiological Effects
Katanosin B and Plusbacin A₃, Inhibitors of Peptidoglycan Synthesis in Methicillin-ResistantStaphylococcus aureus
Hideki Maki, Kenji Miura, Yoshinori Yamano
Mechanisms of Action: Physiological Effects
Staphylococcus aureus Cell Extract Transcription-Translation Assay: Firefly Luciferase Reporter System for Evaluating Protein Translation Inhibitors
Robert W. Murray, Earline P. Melchior, Jeanne C. Hagadorn, Keith R. Marotti
Mechanisms of Action: Physiological Effects
Azithromycin Inhibits Quorum Sensing in Pseudomonas aeruginosa
Kazuhiro Tateda, Rachel Comte, Jean-Claude Pechere, Thilo Köhler, Keizo Yamaguchi, Christian Van Delden

Pharmacology

Pharmacology
Pharmacokinetic-Pharmacodynamic Modeling of the Electroencephalogram Effect of Imipenem in Healthy Rats
Antoine Dupuis, William Couet, Joël Paquereau, Stanley Debarre, Agnès Portron, Candice Jamois, Serge Bouquet
Pharmacology
Uptake, Transport, and Delivery of Antimicrobial Agents by Human Polymorphonuclear Neutrophils
Gerald L. Mandell, Elizabeth Coleman
Pharmacology
Population Pharmacokinetics of Intramuscular Quinine in Children with Severe Malaria
Sanjeev Krishna, Nelamangala V. Nagaraja, Tim Planche, Tsiri Agbenyega, George Bedo-Addo, Daniel Ansong, Alex Owusu-Ofori, Albert L. Shroads, George Henderson, Alan Hutson, Hartmut Derendorf, Peter W. Stacpoole
Pharmacology
Pharmacokinetics and Tissue Penetration of Linezolid following Multiple Oral Doses
Thekli Gee, Richard Ellis, Gillian Marshall, Jenny Andrews, Janet Ashby, Richard Wise
Pharmacology
Antibacterial Properties of Gemifloxacin and Trovafloxacin in Urine Ex Vivo: Phase I Study
Gloria Garcı́a-Calvo, Araceli Parra, Lorenzo Aguilar, Carmen Ponte, Marı́a J. Giménez, Antonio Carcas, Martina Kinzig-Schippers, Francisco Soriano
Pharmacology
Sputum Itraconazole Concentrations in Cystic Fibrosis Patients
I. Sermet-Gaudelus, A. Lesne-Hulin, G. Lenoir, E. Singlas, P. Berche, C. Hennequin

Susceptibility

Susceptibility
Antimicrobial Resistance among Clinical Isolates ofStreptococcus pneumoniae in the United States during 1999–2000, Including a Comparison of Resistance Rates since 1994–1995
Gary V. Doern, Kristopher P. Heilmann, Holly K. Huynh, Paul R. Rhomberg, Stacy L. Coffman, Angela B. Brueggemann
Susceptibility
In Vitro Activities of Antibiotics againstPlasmodium falciparum Are Inhibited by Iron
Bruno Pradines, Christophe Rogier, Thierry Fusai, Joel Mosnier, William Daries, Eric Barret, Daniel Parzy
Susceptibility
Drug Susceptibility Testing of Anaerobic Protozoa
Jacqueline A. Upcroft, Peter Upcroft
Susceptibility
Optimal Susceptibility Testing Conditions for Detection of Azole Resistance in Aspergillus spp.: NCCLS Collaborative Evaluation
A. Espinel-Ingroff, M. Bartlett, V. Chaturvedi, M. Ghannoum, K. C. Hazen, M. A. Pfaller, M. Rinaldi, T. J. Walsh
Susceptibility
In Vitro Activities of Ertapenem (MK-0826) against Recent Clinical Bacteria Collected in Europe and Australia
David M. Livermore, Michael W. Carter, Simone Bagel, Bernd Wiedemann, Fernando Baquero, Elena Loza, Hubert P. Endtz, Nicole van den Braak, Clarence J. Fernandes, Lorna Fernandes, Niels Frimodt-Moller, Laura S. Rasmussen, Helen Giamarellou, Evangelos Giamarellos-Bourboulis, Vincent Jarlier, Jacqueline Nguyen, Carl-Erik Nord, Marc J. Struelens, Caire Nonhoff, John Turnidge, Jan Bell, Reinhard Zbinden, Stefan Pfister, Lori Mixson, Daniel L. Shungu
Susceptibility
In Vitro Activities of Terbinafine againstAspergillus Species in Comparison with Those of Itraconazole and Amphotericin B
Caroline B. Moore, Caroline M. Walls, David W. Denning
Susceptibility
In Vitro Activities of DU-1102, a New Trioxaquine Derivative, against Plasmodium falciparum Isolates
Leonardo K. Basco, Odile Dechy-Cabaret, Mathieu Ndounga, Fleurette Solange Meche, Anne Robert, Bernard Meunier
Susceptibility
Effects of Synthetic Cecropin Analogs on in Vitro Growth of Acholeplasma laidlawii
Wayne B. Borth, V. P. Jones, D. E. Ullman, J. S. Hu
Susceptibility
Comparative In Vitro Activities of Gemifloxacin, Other Quinolones, and Nonquinolone Antimicrobials against Obligately Anaerobic Bacteria
Niels Kleinkauf, Grit Ackermann, Reiner Schaumann, Arne C. Rodloff
Susceptibility
Azasordarins: Susceptibility of Fluconazole-Susceptible and Fluconazole-Resistant Clinical Isolates ofCandida spp. to GW 471558
Manuel Cuenca-Estrella, Emilia Mellado, Teresa M. Dı́az-Guerra, Araceli Monzón, Juan L. Rodrı́guez-Tudela
Susceptibility
In Vitro Activities of Moxifloxacin and Other Fluoroquinolones against Mycoplasma pneumoniae
Kumiko Hamamoto, Takashi Shimizu, Naoyuki Fujimoto, Ye Zhang, Sumio Arai
Susceptibility
Evaluation of Susceptibility Testing To Detect Fluoroquinolone Resistance Mechanisms in Streptococcus pneumoniae
David C. Richardson, Darrin Bast, Allison McGeer, Donald E. Low
Susceptibility
In Vitro Activities of Ertapenem (MK-0826) against Clinical Bacterial Isolates from 11 North American Medical Centers
Peter C. Fuchs, Arthur L. Barry, Steven D. Brown
Susceptibility
In Vitro Activities of Daptomycin against 2,789 Clinical Isolates from 11 North American Medical Centers
Arthur L. Barry, Peter C. Fuchs, Steven D. Brown
Susceptibility
In Vitro Activities of Three Nonfluorinated Quinolones against Representative Bacterial Isolates
Arthur L. Barry, Peter C. Fuchs, Steven D. Brown
Susceptibility
In Vitro Growth of Leishmania amazonensisPromastigotes Resistant to Pentamidine Is Dependent on Interactions among Strains
P. Agnew, P. Holzmuller, Y. Michalakis, D. Sereno, J. L. Lemesre, F. Renaud

Biologic Response Modifiers

Biologic Response Modifiers
Antimicrobial Activity of Intraurethrally Administered Probiotic Lactobacillus casei in a Murine Model of Escherichia coli Urinary Tract Infection
Takashi Asahara, Koji Nomoto, Masaaki Watanuki, Teruo Yokokura

Clinical Therapeutics

Clinical Therapeutics
Salmonella Excretion after Cessation of Tosufloxacin Therapy in Acute Nontyphoid Salmonella Enterocolitis
Kenji Ohnishi, Kyoko Kimura

Analytical Procedures

Analytical Procedures
Kanamycin Susceptibility Testing of Mycobacterium tuberculosis Using Mycobacterium Growth Indicator Tube and a Colorimetric Method
Ivan Bastian, Leen Rigouts, Juan Carlos Palomino, Françoise Portaels

Letters

LETTERS TO THE EDITOR
Carbapenem-Resistant Klebsiella pneumoniae in Singapore Producing IMP-1 β-Lactamase and Lacking an Outer Membrane Protein
Tse H. Koh, Li-Hwei Sng, Gioia S. Babini, Neil Woodford, David M. Livermore, Lucinda M. C. Hall

Errata

Erratum
Activities of the Combination of Quinupristin-Dalfopristin with Rifampin In Vitro and in Experimental Endocarditis Due to Staphylococcus aureus Strains with Various Phenotypes of Resistance to Macrolide-Lincosamide-Streptogramin Antibiotics
Virginie Zarrouk, Bülent Bozdogan, Roland Leclercq, Louis Garry, Celine Feger, Claude Carbon, Bruno Fantin

Main menu

User menu

Search

Table of Contents

Mechanisms of Resistance

Antiviral Agents

Experimental Therapeutics

Mechanisms of Action

Pharmacology

Susceptibility

Biologic Response Modifiers

Clinical Therapeutics

Analytical Procedures

Letters

Errata

In This Issue

Jump to