Letter to the Editor

Effect of Linezolid in Comparison with That of Vancomycin on Glycocalix Production: In Vitro Study

L. Drago, E. De Vecchi, M. Valli, L. Nicola, M. R. Gismondo
DOI: 10.1128/AAC.46.2.598-599.2002

Article Figures & Data

Figures

  • FIG. 1.
    FIG. 1.

    Bacterial slime of staphylococci before treatment with linezolid and vancomycin (A) or after treatment with 0.5 times the MIC of linezolid (B), 0.25 times the MIC of linezolid (C), or 0.5 times the MIC of vancomycin (D).

Tables

  • TABLE 1.

    Effects of subinhibitory concentrations of linezolid and vancomycin on slime production of S. aureus (n = 8)

    OD340 (mean ± SEM)
    Control0.5× MICa0.25× MICa
    Linezolid0.353 ± 0.0950.063 ± 0.032*0.136 ± 0.056*
    Vancomycin0.353 ± 0.0950.069 ± 0.048*0.191 ± 0.107

    • ↵ a *, P < 0.05 versus control.

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KEYWORDS

Acetamides
Glycocalyx
oxazolidinones
Staphylococcus aureus
vancomycin

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