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Mechanisms of Action: Physiological Effects

Mefloquine and New Related Compounds Target the F0 Complex of the F0F1 H+-ATPase of Streptococcus pneumoniae

Antonio Javier Martín-Galiano, Begoña Gorgojo, Calvin M. Kunin, Adela G. de la Campa
Antonio Javier Martín-Galiano
1Unidad de Genética Bacteriana (Consejo Superior de Investigaciones Científicas), Centro Nacional de Microbiología, Instituto de Salud Carlos III, 28220 Majadahonda, Madrid, Spain
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Begoña Gorgojo
1Unidad de Genética Bacteriana (Consejo Superior de Investigaciones Científicas), Centro Nacional de Microbiología, Instituto de Salud Carlos III, 28220 Majadahonda, Madrid, Spain
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Calvin M. Kunin
2Department of Internal Medicine, The Ohio State University, Columbus, Ohio
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Adela G. de la Campa
1Unidad de Genética Bacteriana (Consejo Superior de Investigaciones Científicas), Centro Nacional de Microbiología, Instituto de Salud Carlos III, 28220 Majadahonda, Madrid, Spain
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  • For correspondence: agcampa@isciii.es
DOI: 10.1128/AAC.46.6.1680-1687.2002
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Article Information

DOI 
https://doi.org/10.1128/AAC.46.6.1680-1687.2002
PubMed 
12019076

Published By 
American Society for Microbiology Journals
History 
  • Received November 26, 2001
  • Returned for modification February 7, 2002
  • Accepted February 26, 2002
  • Published online June 1, 2002.

Copyright & Usage 
Copyright © 2002 American Society for Microbiology

Author Information

  1. Antonio Javier Martín-Galiano1,
  2. Begoña Gorgojo1,
  3. Calvin M. Kunin2 and
  4. Adela G. de la Campa1*
  1. 1Unidad de Genética Bacteriana (Consejo Superior de Investigaciones Científicas), Centro Nacional de Microbiología, Instituto de Salud Carlos III, 28220 Majadahonda, Madrid, Spain
  2. 2Department of Internal Medicine, The Ohio State University, Columbus, Ohio
  • ↵* Corresponding author. Mailing address: Unidad de Genética Bacteriana (Consejo Superior de Investigaciones Científicas), Centro Nacional de Microbiología, Instituto de Salud Carlos III, 28220 Majadahonda, Madrid, Spain Phone: (341) 509-7904. Fax: (341) 509-7919. E-mail: agcampa{at}isciii.es .

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Mefloquine and New Related Compounds Target the F0 Complex of the F0F1 H+-ATPase of Streptococcus pneumoniae
Antonio Javier Martín-Galiano, Begoña Gorgojo, Calvin M. Kunin, Adela G. de la Campa
Antimicrobial Agents and Chemotherapy Jun 2002, 46 (6) 1680-1687; DOI: 10.1128/AAC.46.6.1680-1687.2002

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Mefloquine and New Related Compounds Target the F0 Complex of the F0F1 H+-ATPase of Streptococcus pneumoniae
Antonio Javier Martín-Galiano, Begoña Gorgojo, Calvin M. Kunin, Adela G. de la Campa
Antimicrobial Agents and Chemotherapy Jun 2002, 46 (6) 1680-1687; DOI: 10.1128/AAC.46.6.1680-1687.2002
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KEYWORDS

antimalarials
mefloquine
Proton-Translocating ATPases
Streptococcus pneumoniae

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