Enzymes Associated with Reductive Activation and Action of Nitazoxanide, Nitrofurans, and Metronidazole in Helicobacter pylori

Gary Sisson; Avery Goodwin; Ausra Raudonikiene; Nicky J. Hughes; Asish K. Mukhopadhyay; Douglas E. Berg; Paul S. Hoffman

doi:10.1128/AAC.46.7.2116-2123.2002

DOI: 10.1128/AAC.46.7.2116-2123.2002

Article Information

DOI

https://doi.org/10.1128/AAC.46.7.2116-2123.2002

PubMed

12069963

Published By

American Society for Microbiology Journals

History

Received December 17, 2001
Returned for modification February 27, 2002
Accepted April 10, 2002
Published online July 1, 2002.

Author Information

Gary Sisson¹,
Avery Goodwin¹,²,
Ausra Raudonikiene¹,
Nicky J. Hughes²,
Asish K. Mukhopadhyay³,
Douglas E. Berg³ and
Paul S. Hoffman¹,²,⁴ *

¹Department of Microbiology and Immunology
⁴Division of Infectious Diseases, Department of Medicine, Faculty of Medicine, Dalhousie University, HaliFax, Nova Scotia B3H 4H7
²GlaxoSmithKline, Collegeville, Pennsylvania
³Department of Molecular Microbiology and Department of Genetics, Washington University Medical School, St. Louis, Missouri

↵* Corresponding author. Mailing address: Department of Microbiology and Immunology, Sir Charles Tupper Medical Bldg., Room 7P, Dalhousie University, Halifax, Nova Scotia B3H 4H7, Canada. Phone: (902) 494-3889. Fax: (902) 494-5125. E-mail: phoffman{at}tupdean2.med.dal.ca .

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