DOI: 10.1128/AAC.48.10.4063-4066.2004
Article Figures & Data
Figures
- FIG. 1.
Kaplan-Meier plot of the cumulative mortality of male CD-1 mice challenged with 7.1 × 106 conidia of A. fumigatus (strain 10AF)/mouse through intracerebral inoculation. Groups of mice serving as controls were treated with HPβCD (n = 11) or D5W (n = 10). Six other groups (all n = 10) were treated with AmB at 3 mg/kg; POS at 5, 25, or 100 mg/kg; CAS at 5 mg/kg; or ICZ at 50 mg/kg (twice daily).
- FIG. 2.
Scattergrams reflecting the log10 CFU per indicated organ recovered from the surviving untreated (diluent controls) and treated mice infected with A. fumigatus. Bars, median log10 CFU per organ for each therapy group. A value of 6 represented mice that died of infection (20).
