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Experimental Therapeutics

Disposition of Caspofungin, a Novel Antifungal Agent, in Mice, Rats, Rabbits, and Monkeys

Punam Sandhu, Xin Xu, Peter J. Bondiskey, Suresh K. Balani, Michael L. Morris, Yui S. Tang, Alisha R. Miller, Paul G. Pearson
Punam Sandhu
Department of Drug Metabolism, Merck Research Laboratories, West Point, Pennsylvania 19486
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  • For correspondence: punam_sandhu@merck.com
Xin Xu
Department of Drug Metabolism, Merck Research Laboratories, West Point, Pennsylvania 19486
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Peter J. Bondiskey
Department of Drug Metabolism, Merck Research Laboratories, West Point, Pennsylvania 19486
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Suresh K. Balani
Department of Drug Metabolism, Merck Research Laboratories, West Point, Pennsylvania 19486
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Michael L. Morris
Department of Drug Metabolism, Merck Research Laboratories, West Point, Pennsylvania 19486
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Yui S. Tang
Department of Drug Metabolism, Merck Research Laboratories, West Point, Pennsylvania 19486
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Alisha R. Miller
Department of Drug Metabolism, Merck Research Laboratories, West Point, Pennsylvania 19486
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Paul G. Pearson
Department of Drug Metabolism, Merck Research Laboratories, West Point, Pennsylvania 19486
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DOI: 10.1128/AAC.48.4.1272-1280.2004
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Article Information

DOI 
https://doi.org/10.1128/AAC.48.4.1272-1280.2004
PubMed 
15047529

Published By 
American Society for Microbiology Journals
History 
  • Received October 10, 2003
  • Returned for modification November 5, 2003
  • Accepted November 24, 2003
  • Published online March 26, 2004.

Copyright & Usage 
Copyright © 2004 American Society for Microbiology

Author Information

  1. Punam Sandhu*,
  2. Xin Xu‡,
  3. Peter J. Bondiskey§,
  4. Suresh K. Balani¶,
  5. Michael L. Morris†,
  6. Yui S. Tang,
  7. Alisha R. Miller and
  8. Paul G. Pearson∥
  1. Department of Drug Metabolism, Merck Research Laboratories, West Point, Pennsylvania 19486
  • ↵* Corresponding author. Mailing address: Department of Drug Metabolism, WP75A-203, Merck Research Laboratories, West Point, PA 19486. Phone: (215) 652-9308. Fax: (215) 652-2410. E-mail: punam_sandhu{at}merck.com .
  • ↵† Deceased.

  • ↵‡ Present address: Department of Drug Safety and Metabolism, Wyeth Pharmaceutical, Andover, MA 01810.; § Present address: Department of Vaccine and Sterile Quality Operations, Merck Manufacturing Division, West Point, PA 19486.; ¶ Present address: Department of Drug Safety and Disposition, Millennium Pharmaceuticals, Inc., Cambridge, MA 02139.; ∥ Present address: Department of Pharmacokinetics and Drug Metabolism, Amgen, Thousand Oaks, CA 91320.

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Disposition of Caspofungin, a Novel Antifungal Agent, in Mice, Rats, Rabbits, and Monkeys
Punam Sandhu, Xin Xu, Peter J. Bondiskey, Suresh K. Balani, Michael L. Morris, Yui S. Tang, Alisha R. Miller, Paul G. Pearson
Antimicrobial Agents and Chemotherapy Mar 2004, 48 (4) 1272-1280; DOI: 10.1128/AAC.48.4.1272-1280.2004

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Disposition of Caspofungin, a Novel Antifungal Agent, in Mice, Rats, Rabbits, and Monkeys
Punam Sandhu, Xin Xu, Peter J. Bondiskey, Suresh K. Balani, Michael L. Morris, Yui S. Tang, Alisha R. Miller, Paul G. Pearson
Antimicrobial Agents and Chemotherapy Mar 2004, 48 (4) 1272-1280; DOI: 10.1128/AAC.48.4.1272-1280.2004
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KEYWORDS

antifungal agents
peptides
Peptides, Cyclic

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